Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin

Toxicology Letters

Volumn 205, Issue 3, 2011, Pages 293-301

  Jain, Anil K ^a   Tewari Singh, Neera ^a   Gu, Mallikarjuna ^a   Inturi, Swetha ^a   White, Carl W ^b   Agarwal, Rajesh ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

Author keywords

CEES; DNA damage; Inflammatory mediators; Oxidative stress; SKH 1 hairless mice; Skin injury; Sulfur mustard

Indexed keywords

CYCLOOXYGENASE 2; ETHYL 2 CHLOROETHYL SULFIDE; GELATINASE B; GLUTATHIONE; HISTONE H2AX; INDUCIBLE NITRIC OXIDE SYNTHASE; MUSTARD GAS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; FEMALE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN INJURY; SKIN TOXICITY;

ALKYLATING AGENTS; ANIMALS; ANTIDOTES; BLISTER; CHEMICAL WARFARE AGENTS; CYCLOOXYGENASE 2; DERMATITIS, CONTACT; DNA DAMAGE; FEMALE; GLUTATHIONE; HISTONES; INFLAMMATION MEDIATORS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, HAIRLESS; MUSTARD GAS; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SKIN;

MUS;

EID: 79960906205     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.06.019     Document Type: Article

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