Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice

Free Radical Biology and Medicine

Volumn 47, Issue 11, 2009, Pages 1640-1651

  Pal, Arttatrana ^a   Tewari Singh, Neera ^a   Gu, Mallikarjuna ^a   Agarwal, Chapla ^a   Huang, Jie ^b   Day, Brian J ^b   White, Carl W ^b   Agarwal, Rajesh ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

Author keywords

4 HNE; Akt; AP 1; CEES; DMPO; Free radicals; MAPKs; NF B; Oxidative stress; SKH 1 hairless mice

Indexed keywords

4 HYDROXYNONENAL; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ETHYL 2 CHLOROETHYL SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MUSTARD GAS DERIVATIVE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; SERINE; STRESS ACTIVATED PROTEIN KINASE; THREONINE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DNA DAMAGE; ENZYME PHOSPHORYLATION; EXPOSURE; FEMALE; HAIRLESS MOUSE; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SKIN INFLAMMATION; SKIN TOXICITY; TOXICITY TESTING;

ALDEHYDES; ANIMALS; CYCLIC N-OXIDES; DEOXYADENOSINES; DERMATITIS, IRRITANT; DNA DAMAGE; FEMALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, HAIRLESS; MUSTARD GAS; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; SKIN; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

MUS;

EID: 70350622847     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.09.011     Document Type: Article

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