Colchicine effect on P-glycoprotein expression and activity: In silico and in vitro studies

Chemico-Biological Interactions

Volumn 218, Issue , 2014, Pages 50-62

  Silva, Renata ^a   Carmo, Helena ^a   Vilas Boas, Vânia ^a   Barbosa, Daniel José ^a   Palmeira, Andreia ^a   Sousa, Emília ^a,b   Carvalho, Félix ^a   De Lourdes Bastos, Maria ^a   Remião, Fernando ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

ATPase activity; Caco 2 cells; Colchicine; In silico; P glycoprotein induction; P glycoprotein transport activity

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COLCHICINE; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; BINDING AFFINITY; CACO 2 CELL LINE; COMPETITIVE INHIBITION; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; PHARMACOPHORE; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ATPASE ACTIVITY; CACO-2 CELLS; COLCHICINE; IN SILICO; P-GLYCOPROTEIN INDUCTION; P-GLYCOPROTEIN TRANSPORT ACTIVITY;

BINDING, COMPETITIVE; CACO-2 CELLS; COLCHICINE; COMPUTER SIMULATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; P-GLYCOPROTEIN;

EID: 84901254592     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.04.009     Document Type: Article

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