In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells

Archives of Toxicology

Volumn 85, Issue 4, 2011, Pages 315-326

  Silva, Renata ^a   Carmo, Helena ^a   Dinis Oliveira, Ricardo ^a,b,c   Cordeiro Da Silva, Anabela ^a,d   Lima, Sofia Costa ^d   Carvalho, Félix ^a   De Lourdes Bastos, Maria ^a   Remião, Fernando ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b University of Porto   (Portugal)

^c CESPU   (Portugal)

^d UNIVERSITY OF PORTO   (Portugal)

Author keywords

Caco 2 cells; P glycoprotein induction; P glycoprotein transport activity; Paraquat toxicity

Indexed keywords

DOXORUBICIN; GLYCOPROTEIN P; PARAQUAT;

ARTICLE; CELL PROTECTION; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ANTIDOTES; CACO-2 CELLS; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG ANTAGONISM; ENTEROCYTES; FLUORESCENT DYES; HUMANS; P-GLYCOPROTEIN; PARAQUAT; RHODAMINE 123;

EID: 79954426149     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-010-0587-8     Document Type: Article

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