Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein

Molecular Pharmacology

Volumn 79, Issue 3, 2011, Pages 443-452

  Parveen, Zahida ^a   Stockner, Thomas ^a   Bentele, Caterina ^a   Pferschy, Sandra ^a   Kraupp, Martin ^a   Freissmuth, Michael ^a   Ecker, Gerhard F ^b   Chiba, Peter ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 [3 [4 (4 FLUOROPHENYL)PIPERAZIN 1 YL] 2 HYDROXYPROPOXY]PHENYL] 3 PHENYLPROPAN 1 ONE; GLYCOPROTEIN P; GPV 31; GPV 366; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1A; N [2 HYDROXY 3 [2 (3 PHENYLPROPANOYL)PHENOXY]PROPYL] N PROPYLBENZAMIDE; PROPAFENONE; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL; VINBLASTINE;

AMINO ACID SEQUENCE; ARTICLE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG BINDING; DRUG TRANSPORT; GENE MUTATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SITE DIRECTED MUTAGENESIS;

ANIMALS; HEK293 CELLS; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RHODAMINE 123; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79951973326     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.067611     Document Type: Article

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