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Volumn 82, Issue , 2014, Pages 101-107

Spinal inhibitory circuits and their role in motor neuron degeneration

Author keywords

Acetylcholine; Amyotrophic lateral sclerosis; GABA; Glycine; Inhibitory circuits; Renshaw cell; Spinal motor neuron degeneration

Indexed keywords

GLUTAMATE RECEPTOR; NEUROTRANSMITTER;

EID: 84901194074     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.10.003     Document Type: Review
Times cited : (35)

References (107)
  • 1
    • 36248944979 scopus 로고    scopus 로고
    • Heterogeneity of V2-derived interneurons in the adult mouse spinal cord
    • DOI 10.1111/j.1460-9568.2007.05907.x
    • A. Al-Mosawie, J.M. Wilson, and R.M. Brownstone Heterogeneity of V2-derived interneurons in the adult mouse spinal cord Eur. J. Neurosci. 26 2007 3003 3015 (Pubitemid 350135168)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.11 , pp. 3003-3015
    • Al-Mosawie, A.1    Wilson, J.M.2    Brownstone, R.M.3
  • 2
    • 34848922166 scopus 로고    scopus 로고
    • The continuing case for the Renshaw cell
    • DOI 10.1113/jphysiol.2007.136200
    • F.J. Alvarez, and R.E. Fyffe The continuing case for the Renshaw cell J. Physiol. 584 2007 31 45 (Pubitemid 47500538)
    • (2007) Journal of Physiology , vol.584 , Issue.1 , pp. 31-45
    • Alvarez, F.J.1    Fyffe, R.E.W.2
  • 4
    • 0032579782 scopus 로고    scopus 로고
    • Distribution of 5-hydroxytryptamine-immunoreactive boutons on α- motoneurons in the lumbar spinal cord of adult cats
    • DOI 10.1002/(SICI)1096-9861(19980330)393:1<69::AID-CNE7>3.0.CO;2-O
    • F.J. Alvarez, J.C. Pearson, D. Harrington, D. Dewey, L. Torbeck, and R.E. Fyffe Distribution of 5-hydroxytryptamine-immunoreactive boutons on alpha-motoneurons in the lumbar spinal cord of adult cats J. Comp. Neurol. 393 1998 69 83 (Pubitemid 28120067)
    • (1998) Journal of Comparative Neurology , vol.393 , Issue.1 , pp. 69-83
    • Alvarez, F.J.1    Pearson, J.C.2    Harrington, D.3    Dewey, D.4    Torbeck, L.5    Fyffe, R.E.W.6
  • 5
    • 58349092087 scopus 로고    scopus 로고
    • Excitatory and inhibitory intermediate zone interneurons in pathways from feline group i and II afferents: Differences in axonal projections and input
    • B.A. Bannatyne, T.T. Liu, I. Hammar, K. Stecina, E. Jankowska, and D.J. Maxwell Excitatory and inhibitory intermediate zone interneurons in pathways from feline group I and II afferents: differences in axonal projections and input J. Physiol. 587 2009 379 399
    • (2009) J. Physiol. , vol.587 , pp. 379-399
    • Bannatyne, B.A.1    Liu, T.T.2    Hammar, I.3    Stecina, K.4    Jankowska, E.5    Maxwell, D.J.6
  • 6
    • 0025264485 scopus 로고
    • The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat
    • DOI 10.1016/0006-8993(90)90435-E
    • H. Barbeau, and S. Rossignol The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat Brain Res. 514 1990 55 67 (Pubitemid 20147587)
    • (1990) Brain Research , vol.514 , Issue.1 , pp. 55-67
    • Barbeau, H.1    Rossignol, S.2
  • 7
    • 11144227641 scopus 로고    scopus 로고
    • Peptidergic neuromodulation of the lumbar locomotor network in the neonatal rat spinal cord
    • DOI 10.1016/j.peptides.2004.09.002, PII S0196978104003997
    • G. Barriere, S. Bertrand, and J.R. Cazalets Peptidergic neuromodulation of the lumbar locomotor network in the neonatal rat spinal cord Peptides 26 2005 277 286 (Pubitemid 40051423)
    • (2005) Peptides , vol.26 , Issue.2 , pp. 277-286
    • Barriere, G.1    Bertrand, S.2    Cazalets, J.-R.3
  • 8
    • 0030801095 scopus 로고    scopus 로고
    • Modulation of the spinal network for locomotion by substance P in the neonatal rat
    • DOI 10.1007/PL00005718
    • J.Y. Barthe, and F. Clarac Modulation of the spinal network for locomotion by substance P in the neonatal rat Exp. Brain Res. 115 1997 485 492 (Pubitemid 27296446)
    • (1997) Experimental Brain Research , vol.115 , Issue.3 , pp. 485-492
    • Barthe, J.-Y.1    Clarac, F.2
  • 10
    • 0030272426 scopus 로고    scopus 로고
    • GABA transporter heterogeneity: Pharmacology and cellular localization
    • DOI 10.1016/0197-0186(95)00158-1
    • L.A. Borden GABA transporter heterogeneity: pharmacology and cellular localization Neurochem. Int. 29 1996 335 356 (Pubitemid 26297678)
    • (1996) Neurochemistry International , vol.29 , Issue.4 , pp. 335-356
    • Borden, L.A.1    Caplan, M.J.2
  • 12
    • 78649490837 scopus 로고    scopus 로고
    • Spinal interneurons providing input to the final common path during locomotion
    • R.M. Brownstone, and T.V. Bui Spinal interneurons providing input to the final common path during locomotion Prog. Brain Res. 187 2010 81 95
    • (2010) Prog. Brain Res. , vol.187 , pp. 81-95
    • Brownstone, R.M.1    Bui, T.V.2
  • 13
    • 0015041150 scopus 로고
    • Spatial synaptic distribution of recurrent and group Ia inhibitory systems in cat spinal motoneurons
    • R.E. Burke, L. Fedina, and A. Lundberg Spatial synaptic distribution of recurrent and group Ia inhibitory systems in cat spinal motoneurons J. Physiol. 214 1971 305 326
    • (1971) J. Physiol. , vol.214 , pp. 305-326
    • Burke, R.E.1    Fedina, L.2    Lundberg, A.3
  • 14
    • 0033608780 scopus 로고    scopus 로고
    • Distribution of 5-hydroxytryptamine-immunoreactive boutons on immunohistochemically-identified Renshaw cells in cat and rat lumbar spinal cord
    • DOI 10.1016/S0006-8993(98)01210-4, PII S0006899398012104
    • P.A. Carr, J.C. Pearson, and R.E. Fyffe Distribution of 5-hydroxytryptamine-immunoreactive boutons on immunohistochemically-identified Renshaw cells in cat and rat lumbar spinal cord Brain Res. 823 1999 198 201 (Pubitemid 29225509)
    • (1999) Brain Research , vol.823 , Issue.1-2 , pp. 198-201
    • Carr, P.A.1    Pearson, J.C.2    Fyffe, R.E.W.3
  • 15
    • 53149091651 scopus 로고    scopus 로고
    • GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis
    • I. Carunchio, C. Mollinari, M. Pieri, D. Merlo, and C. Zona GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis Eur. J. Neurosci. 28 2008 1275 1285
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 1275-1285
    • Carunchio, I.1    Mollinari, C.2    Pieri, M.3    Merlo, D.4    Zona, C.5
  • 16
    • 84888172861 scopus 로고    scopus 로고
    • Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis
    • C. Casas, M. Herrando-Grabulosa, R. Manzano, R. Mancuso, R. Osta, and X. Navarro Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis Brain Behav. 3 2013 145 158
    • (2013) Brain Behav. , vol.3 , pp. 145-158
    • Casas, C.1    Herrando-Grabulosa, M.2    Manzano, R.3    Mancuso, R.4    Osta, R.5    Navarro, X.6
  • 17
    • 59649104173 scopus 로고    scopus 로고
    • Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: A quantitative confocal analysis
    • Q. Chang, and L.J. Martin Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: a quantitative confocal analysis Am. J. Pathol. 174 2009 574 585
    • (2009) Am. J. Pathol. , vol.174 , pp. 574-585
    • Chang, Q.1    Martin, L.J.2
  • 18
    • 79951991424 scopus 로고    scopus 로고
    • Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis
    • Q. Chang, and L.J. Martin Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurosci. 31 2011 2815 2827
    • (2011) J. Neurosci. , vol.31 , pp. 2815-2827
    • Chang, Q.1    Martin, L.J.2
  • 19
    • 79960831560 scopus 로고    scopus 로고
    • Motoneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis
    • Q. Chang, and L.J. Martin Motoneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis Channels (Austin) 5 2011 299 303
    • (2011) Channels (Austin) , vol.5 , pp. 299-303
    • Chang, Q.1    Martin, L.J.2
  • 20
    • 84881275424 scopus 로고    scopus 로고
    • Genetics of amyotrophic lateral sclerosis: An update
    • S. Chen, P. Sayana, X. Zhang, and W. Le Genetics of amyotrophic lateral sclerosis: an update Mol. Neurodegener. 8 2013 28
    • (2013) Mol. Neurodegener. , vol.8 , pp. 28
    • Chen, S.1    Sayana, P.2    Zhang, X.3    Le, W.4
  • 21
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • DOI 10.1038/35097565
    • D.W. Cleveland, and J.D. Rothstein From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS Nat. Rev. Neurosci. 2 2001 806 819 (Pubitemid 33674062)
    • (2001) Nature Reviews Neuroscience , vol.2 , Issue.11 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 22
    • 0018174024 scopus 로고
    • A new projection from locus coeruleus to the spinal ventral columns: Histochemical and biochemical evidence
    • DOI 10.1016/0006-8993(78)90391-8
    • J.W. Commissiong, S.O. Hellstrom, and N.H. Neff A new projection from locus coeruleus to the spinal ventral columns: histochemical and biochemical evidence Brain Res. 148 1978 207 213 (Pubitemid 8344496)
    • (1978) Brain Research , vol.148 , Issue.1 , pp. 207-213
    • Commissiong, J.W.1    Hellstrom, S.O.2    Neff, N.H.3
  • 23
    • 0032557811 scopus 로고    scopus 로고
    • Neuronal and glial localization of GAT-1, a high-affinity γ- aminobutyric acid plasma membrane transporter, in human cerebral cortex: With a note on its distribution in monkey cortex
    • DOI 10.1002/(SICI)1096-9861(19980622)396:1<51::AID-CNE5>3.0.CO;2-H
    • F. Conti, M. Melone, S. De Biasi, A. Minelli, N.C. Brecha, and A. Ducati Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex J. Comp. Neurol. 396 1998 51 63 (Pubitemid 28242451)
    • (1998) Journal of Comparative Neurology , vol.396 , Issue.1 , pp. 51-63
    • Conti, F.1    Melone, M.2    De Biasi, S.3    Minelli, A.4    Brecha, N.C.5    Ducati, A.6
  • 24
    • 2542498984 scopus 로고    scopus 로고
    • AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo
    • DOI 10.1111/j.1471-4159.2004.02383.x
    • J.C. Corona, and R. Tapia AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo J. Neurochem. 89 2004 988 997 (Pubitemid 38684745)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.4 , pp. 988-997
    • Corona, J.C.1    Tapia, R.2
  • 25
    • 46249106545 scopus 로고    scopus 로고
    • Calpain inhibition protects spinal motoneurons from the excitotoxic effects of AMPA in vivo
    • J.C. Corona, and R. Tapia Calpain inhibition protects spinal motoneurons from the excitotoxic effects of AMPA in vivo Neurochem. Res. 33 2008 1428 1434
    • (2008) Neurochem. Res. , vol.33 , pp. 1428-1434
    • Corona, J.C.1    Tapia, R.2
  • 26
    • 36749049874 scopus 로고    scopus 로고
    • Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis
    • DOI 10.1517/14728222.11.11.1415
    • J.C. Corona, L.B. Tovar-y-Romo, and R. Tapia Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis Expert Opin. Ther. Targets 11 2007 1415 1428 (Pubitemid 350200478)
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , Issue.11 , pp. 1415-1428
    • Corona, J.C.1    Tovar-y-Romo, L.B.2    Tapia, R.3
  • 27
    • 0016809656 scopus 로고
    • On the role of central program and afferent inflow in the control of scratching movements in the cat
    • T.G. Deliagnina, A.G. Feldman, I.M. Gelfand, and G.N. Orlovsky On the role of central program and afferent inflow in the control of scratching movements in the cat Brain Res. 100 1975 297 313
    • (1975) Brain Res. , vol.100 , pp. 297-313
    • Deliagnina, T.G.1    Feldman, A.G.2    Gelfand, I.M.3    Orlovsky, G.N.4
  • 28
    • 84870021561 scopus 로고    scopus 로고
    • Inhibitory glycine receptors: An update
    • S. Dutertre, C.M. Becker, and H. Betz Inhibitory glycine receptors: an update J. Biol. Chem. 287 2012 40216 40223
    • (2012) J. Biol. Chem. , vol.287 , pp. 40216-40223
    • Dutertre, S.1    Becker, C.M.2    Betz, H.3
  • 29
    • 0347939352 scopus 로고    scopus 로고
    • Neurophysiological evaluation of cortical function in the early diagnosis of ALS
    • A. Eisen, and M. Weber Neurophysiological evaluation of cortical function in the early diagnosis of ALS Amyotroph. Lateral Scler. Other Motor Neuron Disord. 1 Suppl. 1 2000 S47 S51
    • (2000) Amyotroph. Lateral Scler. Other Motor Neuron Disord. , vol.1 , Issue.SUPPL. 1
    • Eisen, A.1    Weber, M.2
  • 31
    • 84856496749 scopus 로고    scopus 로고
    • Central pattern generators of the mammalian spinal cord
    • A. Frigon Central pattern generators of the mammalian spinal cord Neuroscientist 18 2012 56 69
    • (2012) Neuroscientist , vol.18 , pp. 56-69
    • Frigon, A.1
  • 32
    • 0025887302 scopus 로고
    • Spatial distribution of recurrent inhibitory synapses on spinal motoneurons in the cat
    • R.E. Fyffe Spatial distribution of recurrent inhibitory synapses on spinal motoneurons in the cat J. Neurophysiol. 65 1991 1134 1149
    • (1991) J. Neurophysiol. , vol.65 , pp. 1134-1149
    • Fyffe, R.E.1
  • 34
    • 84868219299 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Drug therapy from the bench to the bedside
    • S.B. Gibson, and M.B. Bromberg Amyotrophic lateral sclerosis: drug therapy from the bench to the bedside Semin. Neurol. 32 2012 173 178
    • (2012) Semin. Neurol. , vol.32 , pp. 173-178
    • Gibson, S.B.1    Bromberg, M.B.2
  • 35
    • 0034283252 scopus 로고    scopus 로고
    • Coupling between serotoninergic and noradrenergic neurones and gamma-motoneurones in the cat
    • M.H. Gladden, D.J. Maxwell, A. Sahal, and E. Jankowska Coupling between serotoninergic and noradrenergic neurones and gamma-motoneurones in the cat J. Physiol. 527 Pt 2 2000 213 223
    • (2000) J. Physiol. , vol.527 , Issue.PART 2 , pp. 213-223
    • Gladden, M.H.1    Maxwell, D.J.2    Sahal, A.3    Jankowska, E.4
  • 36
    • 82255164207 scopus 로고    scopus 로고
    • The role of genetically-defined interneurons in generating the mammalian locomotor rhythm
    • S. Gosgnach The role of genetically-defined interneurons in generating the mammalian locomotor rhythm Integr. Comp. Biol. 51 2011 903 912
    • (2011) Integr. Comp. Biol. , vol.51 , pp. 903-912
    • Gosgnach, S.1
  • 37
    • 72549088712 scopus 로고    scopus 로고
    • Measured motion: Searching for simplicity in spinal locomotor networks
    • S. Grillner, and T.M. Jessell Measured motion: searching for simplicity in spinal locomotor networks Curr. Opin. Neurobiol. 19 2009 572 586
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 572-586
    • Grillner, S.1    Jessell, T.M.2
  • 39
    • 1642301385 scopus 로고    scopus 로고
    • The actions of monoamines and distribution of noradrenergic and serotoninergic contacts on different subpopulations of commissural interneurons in the cat spinal cord
    • DOI 10.1111/j.1460-9568.2004.03239.x
    • I. Hammar, B.A. Bannatyne, D.J. Maxwell, S.A. Edgley, and E. Jankowska The actions of monoamines and distribution of noradrenergic and serotoninergic contacts on different subpopulations of commissural interneurons in the cat spinal cord Eur. J. Neurosci. 19 2004 1305 1316 (Pubitemid 38387207)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.5 , pp. 1305-1316
    • Hammar, I.1    Bannatyne, B.A.2    Maxwell, D.J.3    Edgley, S.A.4    Jankowska, E.5
  • 40
    • 82855165197 scopus 로고    scopus 로고
    • Neuromodulation and flexibility in Central Pattern Generator networks
    • R.M. Harris-Warrick Neuromodulation and flexibility in Central Pattern Generator networks Curr. Opin. Neurobiol. 21 2011 685 692
    • (2011) Curr. Opin. Neurobiol. , vol.21 , pp. 685-692
    • Harris-Warrick, R.M.1
  • 41
    • 0019491773 scopus 로고
    • Reduced glycine receptor in the spinal cord in amyotrophic lateral sclerosis
    • DOI 10.1002/ana.410090313
    • H. Hayashi, M. Suga, M. Satake, and T. Tsubaki Reduced glycine receptor in the spinal cord in amyotrophic lateral sclerosis Ann. Neurol. 9 1981 292 294 (Pubitemid 11147147)
    • (1981) Annals of Neurology , vol.9 , Issue.3 , pp. 292-294
    • Hayashi, H.1    Suga, M.2    Satake, M.3    Tsubaki, T.4
  • 42
    • 79961022340 scopus 로고    scopus 로고
    • Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice
    • M. Hossaini, S. Cardona Cano, V. van Dis, E.D. Haasdijk, C.C. Hoogenraad, J.C. Holstege, and D. Jaarsma Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice J. Neuropathol. Exp. Neurol. 70 2011 662 677
    • (2011) J. Neuropathol. Exp. Neurol. , vol.70 , pp. 662-677
    • Hossaini, M.1    Cardona Cano, S.2    Van Dis, V.3    Haasdijk, E.D.4    Hoogenraad, C.C.5    Holstege, J.C.6    Jaarsma, D.7
  • 43
    • 79956276658 scopus 로고    scopus 로고
    • Activation of group i metabotropic glutamate receptors modulates locomotor-related motoneuron output in mice
    • N. Iwagaki, and G.B. Miles Activation of group I metabotropic glutamate receptors modulates locomotor-related motoneuron output in mice J. Neurophysiol. 105 2011 2108 2120
    • (2011) J. Neurophysiol. , vol.105 , pp. 2108-2120
    • Iwagaki, N.1    Miles, G.B.2
  • 44
    • 0037338360 scopus 로고    scopus 로고
    • Neuronal basis of crossed actions from the reticular formation on feline hindlimb motoneurons
    • E. Jankowska, I. Hammar, U. Slawinska, K. Maleszak, and S.A. Edgley Neuronal basis of crossed actions from the reticular formation on feline hindlimb motoneurons J. Neurosci. 23 2003 1867 1878 (Pubitemid 36314742)
    • (2003) Journal of Neuroscience , vol.23 , Issue.5 , pp. 1867-1878
    • Jankowska, E.1    Hammar, I.2    Slawinska, U.3    Maleszak, K.4    Edgley, S.A.5
  • 45
    • 0345700290 scopus 로고    scopus 로고
    • Gabapentin therapy for amyotrophic lateral sclerosis: Lack of improvement in neuronal integrity shown by MR spectroscopy
    • S. Kalra, N.R. Cashman, Z. Caramanos, A. Genge, and D.L. Arnold Gabapentin therapy for amyotrophic lateral sclerosis: lack of improvement in neuronal integrity shown by MR spectroscopy AJNR Am. J. Neuroradiol 24 2003 476 480 (Pubitemid 36361991)
    • (2003) American Journal of Neuroradiology , vol.24 , Issue.3 , pp. 476-480
    • Kalra, S.1    Cashman, N.R.2    Caramanos, Z.3    Genge, A.4    Arnold, D.L.5
  • 46
    • 0036382663 scopus 로고    scopus 로고
    • GATA proteins identify a novel ventral interneuron subclass in the developing chick spinal cord
    • A. Karunaratne, M. Hargrave, A. Poh, and T. Yamada GATA proteins identify a novel ventral interneuron subclass in the developing chick spinal cord Dev. Biol. 249 2002 30 43
    • (2002) Dev. Biol. , vol.249 , pp. 30-43
    • Karunaratne, A.1    Hargrave, M.2    Poh, A.3    Yamada, T.4
  • 47
    • 0029862950 scopus 로고    scopus 로고
    • Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat
    • O. Kiehn, and O. Kjaerulff Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat J. Neurophysiol. 75 1996 1472 1482 (Pubitemid 26114058)
    • (1996) Journal of Neurophysiology , vol.75 , Issue.4 , pp. 1472-1482
    • Kiehn, O.1    Kjaerulff, O.2
  • 48
    • 58149139574 scopus 로고    scopus 로고
    • V2a and V2b neurons are generated by the final divisions of pair-producing progenitors in the zebrafish spinal cord
    • Y. Kimura, C. Satou, and S. Higashijima V2a and V2b neurons are generated by the final divisions of pair-producing progenitors in the zebrafish spinal cord Development 135 2008 3001 3005
    • (2008) Development , vol.135 , pp. 3001-3005
    • Kimura, Y.1    Satou, C.2    Higashijima, S.3
  • 51
    • 2342497711 scopus 로고    scopus 로고
    • Genetic identification of spinal interneurons that coordinate left-right locomotor activity necessary for walking movements
    • DOI 10.1016/S0896-6273(04)00249-1, PII S0896627304002491
    • G.M. Lanuza, S. Gosgnach, A. Pierani, T.M. Jessell, and M. Goulding Genetic identification of spinal interneurons that coordinate left-right locomotor activity necessary for walking movements Neuron 42 2004 375 386 (Pubitemid 38610137)
    • (2004) Neuron , vol.42 , Issue.3 , pp. 375-386
    • Lanuza, G.M.1    Gosgnach, S.2    Pierani, A.3    Jessell, T.M.4    Goulding, M.5
  • 52
    • 33745203481 scopus 로고    scopus 로고
    • Differential expression of GABAA and glycine receptors in ALS-resistant vs. ALS-vulnerable motoneurons: Possible implications for selective vulnerability of motoneurons
    • L.E. Lorenzo, A. Barbe, P. Portalier, J.M. Fritschy, and H. Bras Differential expression of GABAA and glycine receptors in ALS-resistant vs. ALS-vulnerable motoneurons: possible implications for selective vulnerability of motoneurons Eur. J. Neurosci. 23 2006 3161 3170
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 3161-3170
    • Lorenzo, L.E.1    Barbe, A.2    Portalier, P.3    Fritschy, J.M.4    Bras, H.5
  • 53
    • 36248989583 scopus 로고    scopus 로고
    • Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord
    • DOI 10.1111/j.1460-9568.2007.05906.x
    • L. Lundfald, C.E. Restrepo, S.J. Butt, C.Y. Peng, S. Droho, T. Endo, H.U. Zeilhofer, K. Sharma, and O. Kiehn Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord Eur. J. Neurosci. 26 2007 2989 3002 (Pubitemid 350135167)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.11 , pp. 2989-3002
    • Lundfald, L.1    Restrepo, C.E.2    Butt, S.J.B.3    Peng, C.-Y.4    Droho, S.5    Endo, T.6    Zeilhofer, H.U.7    Sharma, K.8    Kiehn, O.9
  • 54
    • 0026040366 scopus 로고
    • Amyotrophic lateral sclerosis: Glutamate dehydrogenase and transmitter amino acids in the spinal cord
    • S. Malessa, P.N. Leigh, O. Bertel, E. Sluga, and O. Hornykiewicz Amyotrophic lateral sclerosis: glutamate dehydrogenase and transmitter amino acids in the spinal cord J. Neurol. Neurosurg. Psychiatry 54 1991 984 988
    • (1991) J. Neurol. Neurosurg. Psychiatry , vol.54 , pp. 984-988
    • Malessa, S.1    Leigh, P.N.2    Bertel, O.3    Sluga, E.4    Hornykiewicz, O.5
  • 55
    • 33845361630 scopus 로고    scopus 로고
    • Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death
    • DOI 10.1002/cne.21160
    • L.J. Martin, Z. Liu, K. Chen, A.C. Price, Y. Pan, J.A. Swaby, and W.C. Golden Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death J. Comp. Neurol. 500 2007 20 46 (Pubitemid 44904300)
    • (2007) Journal of Comparative Neurology , vol.500 , Issue.1 , pp. 20-46
    • Martin, L.J.1    Liu, Z.2    Chen, K.3    Price, A.C.4    Yan, P.5    Swaby, J.A.6    Golden, W.C.7
  • 56
    • 0034090696 scopus 로고    scopus 로고
    • Serotoninergic and noradrenergic axonal contacts associated with premotor interneurons in spinal pathways from group II muscle afferents
    • DOI 10.1046/j.1460-9568.2000.00022.x
    • D.J. Maxwell, J.S. Riddell, and E. Jankowska Serotoninergic and noradrenergic axonal contacts associated with premotor interneurons in spinal pathways from group II muscle afferents Eur. J. Neurosci. 12 2000 1271 1280 (Pubitemid 30224231)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.4 , pp. 1271-1280
    • Maxwell, D.J.1    Riddell, J.S.2    Jankowska, E.3
  • 57
    • 77950258755 scopus 로고    scopus 로고
    • Role of Renshaw cells in amyotrophic lateral sclerosis
    • R. Mazzocchio, and A. Rossi Role of Renshaw cells in amyotrophic lateral sclerosis Muscle Nerve 41 2010 441 443
    • (2010) Muscle Nerve , vol.41 , pp. 441-443
    • Mazzocchio, R.1    Rossi, A.2
  • 58
    • 39749149898 scopus 로고    scopus 로고
    • Intrathecal baclofen for spasticity-related pain in amyotrophic lateral sclerosis: Efficacy and factors associated with pain relief
    • DOI 10.1002/mus.20900
    • S. McClelland 3rd, F.A. Bethoux, N.M. Boulis, M.H. Sutliff, D.K. Stough, K.M. Schwetz, D.M. Gogol, M. Harrison, and E.P. Pioro Intrathecal baclofen for spasticity-related pain in amyotrophic lateral sclerosis: efficacy and factors associated with pain relief Muscle Nerve 37 2008 396 398 (Pubitemid 351304800)
    • (2008) Muscle and Nerve , vol.37 , Issue.3 , pp. 396-398
    • McClelland III, S.1    Bethoux, F.A.2    Boulis, N.M.3    Sutliff, M.H.4    Stough, D.K.5    Schwetz, K.M.6    Gogol, D.M.7    Harrison, M.8    Pioro, E.P.9
  • 59
    • 0030734546 scopus 로고    scopus 로고
    • Identification and characterization of the vesicular GABA transporter
    • DOI 10.1038/39908
    • S.L. McIntire, R.J. Reimer, K. Schuske, R.H. Edwards, and E.M. Jorgensen Identification and characterization of the vesicular GABA transporter Nature 389 1997 870 876 (Pubitemid 27462983)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 870-876
    • McIntire, S.L.1    Reimer, R.J.2    Schuske, K.3    Edwards, R.H.4    Jorgensen, E.M.5
  • 60
    • 33845781979 scopus 로고    scopus 로고
    • Primary afferent synapses on developing and adult Renshaw cells
    • DOI 10.1523/JNEUROSCI.2945-06.2006
    • G.Z. Mentis, V.C. Siembab, R. Zerda, M.J. O'Donovan, and F.J. Alvarez Primary afferent synapses on developing and adult Renshaw cells J. Neurosci. 26 2006 13297 13310 (Pubitemid 46011640)
    • (2006) Journal of Neuroscience , vol.26 , Issue.51 , pp. 13297-13310
    • Mentis, G.Z.1    Siembab, V.C.2    Zerda, R.3    O'Donovan, M.J.4    Alvarez, F.J.5
  • 61
    • 77949737571 scopus 로고    scopus 로고
    • In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis
    • M. Milanese, S. Zappettini, E. Jacchetti, T. Bonifacino, C. Cervetto, C. Usai, and G. Bonanno In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis J. Neurochem. 113 2010 489 501
    • (2010) J. Neurochem. , vol.113 , pp. 489-501
    • Milanese, M.1    Zappettini, S.2    Jacchetti, E.3    Bonifacino, T.4    Cervetto, C.5    Usai, C.6    Bonanno, G.7
  • 62
    • 83455163700 scopus 로고    scopus 로고
    • Neuromodulation of vertebrate locomotor control networks
    • G.B. Miles, and K.T. Sillar Neuromodulation of vertebrate locomotor control networks Physiology (Bethesda) 26 2011 393 411
    • (2011) Physiology (Bethesda) , vol.26 , pp. 393-411
    • Miles, G.B.1    Sillar, K.T.2
  • 65
    • 57449092655 scopus 로고    scopus 로고
    • Voronoi-based spatial analysis reveals selective interneuron changes in the cortex of FALS mice
    • D. Minciacchi, R.M. Kassa, C. Del Tongo, R. Mariotti, and M. Bentivoglio Voronoi-based spatial analysis reveals selective interneuron changes in the cortex of FALS mice Exp. Neurol. 215 2009 77 86
    • (2009) Exp. Neurol. , vol.215 , pp. 77-86
    • Minciacchi, D.1    Kassa, R.M.2    Del Tongo, C.3    Mariotti, R.4    Bentivoglio, M.5
  • 66
    • 0032472831 scopus 로고    scopus 로고
    • Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice
    • DOI 10.1002/(SICI)1096-9861(19980202)391:1<64::AID-CNE6>3.0.CO;2-P
    • B.M. Morrison, W.G. Janssen, J.W. Gordon, and J.H. Morrison Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice J. Comp. Neurol. 391 1998 64 77 (Pubitemid 28109620)
    • (1998) Journal of Comparative Neurology , vol.391 , Issue.1 , pp. 64-77
    • Morrison, B.M.1    Janssen, W.G.2    Gordon, J.W.3    Morrison, J.H.4
  • 67
    • 0027329088 scopus 로고
    • Evidence for the cholinergic nature of C-terminals associated with subsurface cisterns in α-motoneurons of rat
    • J.I. Nagy, T. Yamamoto, and L.M. Jordan Evidence for the cholinergic nature of C-terminals associated with subsurface cisterns in alpha-motoneurons of rat Synapse 15 1993 17 32 (Pubitemid 23262752)
    • (1993) Synapse , vol.15 , Issue.1 , pp. 17-32
    • Nagy, J.I.1    Yamamoto, T.2    Jordan, L.M.3
  • 69
    • 79951823551 scopus 로고    scopus 로고
    • Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS
    • J.L. Nieto-Gonzalez, J. Moser, M. Lauritzen, T. Schmitt-John, and K. Jensen Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS Cereb. Cortex 21 2011 625 635
    • (2011) Cereb. Cortex , vol.21 , pp. 625-635
    • Nieto-Gonzalez, J.L.1    Moser, J.2    Lauritzen, M.3    Schmitt-John, T.4    Jensen, K.5
  • 70
    • 0029595287 scopus 로고
    • Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis
    • Y. Oda, S. Imai, I. Nakanishi, T. Ichikawa, and T. Deguchi Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis Pathol. Int. 45 1995 933 939 (Pubitemid 26036958)
    • (1995) Pathology International , vol.45 , Issue.12 , pp. 933-939
    • Oda, Y.1    Imai, S.2    Nakanishi, I.3    Ichikawa, T.4    Deguchi, T.5
  • 72
    • 33747605320 scopus 로고    scopus 로고
    • Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
    • DOI 10.1038/nrn1971, PII NRN1971
    • P. Pasinelli, and R.H. Brown Molecular biology of amyotrophic lateral sclerosis: insights from genetics Nat. Rev. Neurosci. 7 2006 710 723 (Pubitemid 44267495)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.9 , pp. 710-723
    • Pasinelli, P.1    Brown, R.H.2
  • 74
    • 0242442553 scopus 로고    scopus 로고
    • Peptidergic Activation of Locomotor Pattern Generators in the Neonatal Spinal Cord
    • S.A. Pearson, A. Mouihate, Q.J. Pittman, and P.J. Whelan Peptidergic activation of locomotor pattern generators in the neonatal spinal cord J. Neurosci. 23 2003 10154 10163 (Pubitemid 37392564)
    • (2003) Journal of Neuroscience , vol.23 , Issue.31 , pp. 10154-10163
    • Pearson, S.A.1    Mouihate, A.2    Pittman, Q.J.3    Whelan, P.J.4
  • 75
    • 33847772647 scopus 로고    scopus 로고
    • Notch and MAML Signaling Drives Scl-Dependent Interneuron Diversity in the Spinal Cord
    • DOI 10.1016/j.neuron.2007.02.019, PII S0896627307001390
    • C.Y. Peng, H. Yajima, C.E. Burns, L.I. Zon, S.S. Sisodia, S.L. Pfaff, and K. Sharma Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord Neuron 53 2007 813 827 (Pubitemid 46389564)
    • (2007) Neuron , vol.53 , Issue.6 , pp. 813-827
    • Peng, C.-Y.1    Yajima, H.2    Burns, C.E.3    Zon, L.I.4    Sisodia, S.S.5    Pfaff, S.L.6    Sharma, K.7
  • 78
    • 59149096854 scopus 로고    scopus 로고
    • Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression
    • A.H. Pullen, and D. Athanasiou Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression Eur. J. Neurosci. 29 2009 551 561
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 551-561
    • Pullen, A.H.1    Athanasiou, D.2
  • 79
    • 0026649710 scopus 로고
    • Immunocytochemical mapping of noradrenergic projections to the rat spinal cord with an antiserum against noradrenaline
    • N. Rajaofetra, J.L. Ridet, P. Poulat, L. Marlier, F. Sandillon, M. Geffard, and A. Privat Immunocytochemical mapping of noradrenergic projections to the rat spinal cord with an antiserum against noradrenaline J. Neurocytol. 21 1992 481 494
    • (1992) J. Neurocytol. , vol.21 , pp. 481-494
    • Rajaofetra, N.1    Ridet, J.L.2    Poulat, P.3    Marlier, L.4    Sandillon, F.5    Geffard, M.6    Privat, A.7
  • 81
    • 84875441083 scopus 로고    scopus 로고
    • The changing scene of amyotrophic lateral sclerosis
    • W. Robberecht, and T. Philips The changing scene of amyotrophic lateral sclerosis Nat. Rev. Neurosci. 14 2013 248 264
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 248-264
    • Robberecht, W.1    Philips, T.2
  • 82
    • 0029839395 scopus 로고    scopus 로고
    • Reduction of fasciculations in patients with amyotrophic lateral sclerosis with the use of gabapentin [4]
    • J.G. Romano Reduction of fasciculations in patients with amyotrophic lateral sclerosis with the use of gabapentin Arch. Neurol. 53 1996 716 (Pubitemid 26266915)
    • (1996) Archives of Neurology , vol.53 , Issue.8 , pp. 716
    • Romano, J.G.1
  • 83
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • J.D. Rothstein, L.J. Martin, and R.W. Kuncl Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis N. Engl. J. Med. 326 1992 1464 1468
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 84
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • J.D. Rothstein, M. Van Kammen, A.I. Levey, L.J. Martin, and R.W. Kuncl Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis Ann. Neurol. 38 1995 73 84
    • (1995) Ann. Neurol. , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 85
    • 0030840107 scopus 로고    scopus 로고
    • Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases
    • DOI 10.1016/S0014-5793(97)01279-9, PII S0014579397012799
    • C. Sagne, S. El Mestikawy, M.F. Isambert, M. Hamon, J.P. Henry, B. Giros, and B. Gasnier Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases FEBS Lett. 417 1997 177 183 (Pubitemid 27491728)
    • (1997) FEBS Letters , vol.417 , Issue.2 , pp. 177-183
    • Sagne, C.1    El Mestikawy, S.2    Isambert, M.-F.3    Hamon, M.4    Henry, J.-P.5    Giros, B.6    Gasnier, B.7
  • 86
    • 84872878354 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in motor neuron degeneration in ALS
    • M.H. Maurer, InTech Croatia
    • L.D. Santa-Cruz, U.N. Ramírez-Jarquín, and R. Tapia Role of mitochondrial dysfunction in motor neuron degeneration in ALS M.H. Maurer, Amyotrophic Lateral Sclerosis 2012 InTech Croatia 197 224
    • (2012) Amyotrophic Lateral Sclerosis , pp. 197-224
    • Santa-Cruz, L.D.1    Ramírez-Jarquín, U.N.2    Tapia, R.3
  • 87
    • 0026733697 scopus 로고
    • Involvement of GABA and glycine in recurrent inhibition of spinal motoneurons
    • S.P. Schneider, and R.E. Fyffe Involvement of GABA and glycine in recurrent inhibition of spinal motoneurons J. Neurophysiol. 68 1992 397 406
    • (1992) J. Neurophysiol. , vol.68 , pp. 397-406
    • Schneider, S.P.1    Fyffe, R.E.2
  • 88
  • 89
    • 77958535264 scopus 로고    scopus 로고
    • Target selection of proprioceptive and motor axon synapses on neonatal V1-derived Ia inhibitory interneurons and Renshaw cells
    • V.C. Siembab, C.A. Smith, L. Zagoraiou, M.C. Berrocal, G.Z. Mentis, and F.J. Alvarez Target selection of proprioceptive and motor axon synapses on neonatal V1-derived Ia inhibitory interneurons and Renshaw cells J. Comp. Neurol. 518 2010 4675 4701
    • (2010) J. Comp. Neurol. , vol.518 , pp. 4675-4701
    • Siembab, V.C.1    Smith, C.A.2    Zagoraiou, L.3    Berrocal, M.C.4    Mentis, G.Z.5    Alvarez, F.J.6
  • 90
    • 1242295358 scopus 로고    scopus 로고
    • Modulation of rhythmic patterns and cumulative depolarization by group I metabotropic glutamate receptors in the neonatal rat spinal cord in vitro
    • DOI 10.1111/j.0953-816X.2003.03148.x
    • G. Taccola, C. Marchetti, and A. Nistri Modulation of rhythmic patterns and cumulative depolarization by group I metabotropic glutamate receptors in the neonatal rat spinal cord in vitro Eur. J. Neurosci. 19 2004 533 541 (Pubitemid 38241293)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.3 , pp. 533-541
    • Taccola, G.1    Marchetti, C.2    Nistri, A.3
  • 91
    • 3042518935 scopus 로고    scopus 로고
    • Role of group II and III metabotropic glutamate receptors in rhythmic patterns of the neonatal rat spinal cord in vitro
    • DOI 10.1007/s00221-003-1798-5
    • G. Taccola, C. Marchetti, and A. Nistri Role of group II and III metabotropic glutamate receptors in rhythmic patterns of the neonatal rat spinal cord in vitro Exp. Brain Res. 156 2004 495 504 (Pubitemid 38822617)
    • (2004) Experimental Brain Research , vol.156 , Issue.4 , pp. 495-504
    • Taccola, G.1    Marchetti, C.2    Nistri, A.3
  • 92
    • 0029860502 scopus 로고    scopus 로고
    • Diversity and pattern in the developing spinal cord
    • Y. Tanabe, and T.M. Jessell Diversity and pattern in the developing spinal cord Science 274 1996 1115 1123
    • (1996) Science , vol.274 , pp. 1115-1123
    • Tanabe, Y.1    Jessell, T.M.2
  • 93
    • 0025368953 scopus 로고
    • Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat
    • DOI 10.1002/cne.902960312
    • A.J. Todd, and A.C. Sullivan Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat J. Comp. Neurol. 296 1990 496 505 (Pubitemid 20188821)
    • (1990) Journal of Comparative Neurology , vol.296 , Issue.3 , pp. 496-505
    • Todd, A.J.1    Sullivan, A.C.2
  • 94
    • 68949121232 scopus 로고    scopus 로고
    • Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis
    • L.B. Tovar-y-Romo, L.D. Santa-Cruz, and R. Tapia Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis Mol. Neurodegener. 4 2009 31
    • (2009) Mol. Neurodegener. , vol.4 , pp. 31
    • Tovar-Y-Romo, L.B.1    Santa-Cruz, L.D.2    Tapia, R.3
  • 95
    • 60949096316 scopus 로고    scopus 로고
    • Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo
    • L.B. Tovar-y-Romo, L.D. Santa-Cruz, A. Zepeda, and R. Tapia Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo Neurochem. Int. 54 2009 186 191
    • (2009) Neurochem. Int. , vol.54 , pp. 186-191
    • Tovar-Y-Romo, L.B.1    Santa-Cruz, L.D.2    Zepeda, A.3    Tapia, R.4
  • 96
    • 33745270015 scopus 로고    scopus 로고
    • Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade
    • DOI 10.1016/j.expneurol.2005.11.005, PII S0014488605004097
    • L.B. Tovar-y-Romo, and R. Tapia Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade Exp. Neurol. 199 2006 281 290 (Pubitemid 43928956)
    • (2006) Experimental Neurology , vol.199 , Issue.2 , pp. 281-290
    • Tovar-y-Romo, L.B.1    Tapia, R.2
  • 97
    • 78149277977 scopus 로고    scopus 로고
    • VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK
    • L.B. Tovar-y-Romo, and R. Tapia VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK J. Neurochem. 115 2010 1090 1101
    • (2010) J. Neurochem. , vol.115 , pp. 1090-1101
    • Tovar-Y-Romo, L.B.1    Tapia, R.2
  • 98
    • 34948909599 scopus 로고    scopus 로고
    • Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration
    • DOI 10.1097/nen.0b013e3181567c16, PII 0000507220071000000005
    • L.B. Tovar-y-Romo, A. Zepeda, and R. Tapia Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration J. Neuropathol. Exp. Neurol. 66 2007 913 922 (Pubitemid 47530830)
    • (2007) Journal of Neuropathology and Experimental Neurology , vol.66 , Issue.10 , pp. 913-922
    • Tovar-Y-Romo, L.B.1    Zepeda, A.2    Tapia, R.3
  • 99
    • 58149173426 scopus 로고    scopus 로고
    • Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis
    • B. van Zundert, M.H. Peuscher, M. Hynynen, A. Chen, R.L. Neve, R.H. Brown Jr., M. Constantine-Paton, and M.C. Bellingham Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis J. Neurosci. 28 2008 10864 10874
    • (2008) J. Neurosci. , vol.28 , pp. 10864-10874
    • Van Zundert, B.1    Peuscher, M.H.2    Hynynen, M.3    Chen, A.4    Neve, R.L.5    Brown, Jr.R.H.6    Constantine-Paton, M.7    Bellingham, M.C.8
  • 100
    • 0026438284 scopus 로고
    • Characterisation of the distribution of choline acetyltransferase messenger RNA in human spinal cord and its depletion in motor neurone disease
    • L. Virgo, J. de Belleroche, M. Rossi, and T.J. Steiner Characterisation of the distribution of choline acetyltransferase messenger RNA in human spinal cord and its depletion in motor neurone disease J. Neurol. Sci. 112 1992 126 132
    • (1992) J. Neurol. Sci. , vol.112 , pp. 126-132
    • Virgo, L.1    De Belleroche, J.2    Rossi, M.3    Steiner, T.J.4
  • 101
    • 70349748799 scopus 로고    scopus 로고
    • Defining the mechanisms that underlie cortical hyperexcitability in amyotrophic lateral sclerosis
    • S. Vucic, B.C. Cheah, and M.C. Kiernan Defining the mechanisms that underlie cortical hyperexcitability in amyotrophic lateral sclerosis Exp. Neurol. 220 2009 177 182
    • (2009) Exp. Neurol. , vol.220 , pp. 177-182
    • Vucic, S.1    Cheah, B.C.2    Kiernan, M.C.3
  • 102
    • 0020684208 scopus 로고
    • Noradrenergic projections to the spinal cord of the rat
    • DOI 10.1016/0006-8993(83)91196-4
    • K.N. Westlund, R.M. Bowker, M.G. Ziegler, and J.D. Coulter Noradrenergic projections to the spinal cord of the rat Brain Res. 263 1983 15 31 (Pubitemid 13160133)
    • (1983) Brain Research , vol.263 , Issue.1 , pp. 15-31
    • Westlund, K.N.1    Bowker, R.M.2    Ziegler, M.G.3    Coulter, J.D.4
  • 103
    • 0020630063 scopus 로고
    • Amyotrophic lateral sclerosis: Alterations in neurotransmitter receptors
    • P.J. Whitehouse, J.K. Wamsley, M.A. Zarbin, D.L. Price, W.W. Tourtellotte, and M.J. Kuhar Amyotrophic lateral sclerosis: alterations in neurotransmitter receptors Ann. Neurol. 14 1983 8 16 (Pubitemid 13070065)
    • (1983) Annals of Neurology , vol.14 , Issue.1 , pp. 8-16
    • Whitehouse, P.J.1    Wamsley, J.K.2    Zarbin, M.A.3
  • 106
    • 71149108487 scopus 로고    scopus 로고
    • A cluster of cholinergic premotor interneurons modulates mouse locomotor activity
    • L. Zagoraiou, T. Akay, J.F. Martin, R.M. Brownstone, T.M. Jessell, and G.B. Miles A cluster of cholinergic premotor interneurons modulates mouse locomotor activity Neuron 64 2009 645 662
    • (2009) Neuron , vol.64 , pp. 645-662
    • Zagoraiou, L.1    Akay, T.2    Martin, J.F.3    Brownstone, R.M.4    Jessell, T.M.5    Miles, G.B.6


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