Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection

Neurobiology of Disease

Volumn 21, Issue 3, 2006, Pages 556-567

  Ganel, Raquelli ^a   Ho, Tony ^a   Maragakis, Nicholas J ^a   Jackson, Mandy ^a   Steiner, Joseph P ^a   Rothstein, Jeffrey D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ALS; EAAT2; GLT1; Glutamate; Motor neuron; Neuroimmunophilin; Neuroprotection; Transport

Indexed keywords

1 (3,3 DIMETHYL 1,2 DIOXOPENTYL) 2 PYRROLIDINECARBOXYLIC ACID 3 (3 PYRIDYL)PROPYL ESTER; DIHYDROKAINIC ACID; GLT1; GLUTAMATE TRANSPORTER; NEUROIMMUNOPHILIN; SODIUM; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DISEASE MODEL; EXCITOTOXICITY; FEMALE; GLIA; MALE; MOTONEURON; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SURVIVAL; UPREGULATION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID TRANSPORTER 2; FEMALE; IMMUNOBLOTTING; LIGANDS; MALE; MICE; MICE, TRANSGENIC; NEUROGLIA; NEUROPROTECTIVE AGENTS; ORGAN CULTURE TECHNIQUES; PYRROLIDINES; RATS; SPINAL CORD; TACROLIMUS BINDING PROTEINS; UP-REGULATION;

EID: 33244464506     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.08.014     Document Type: Article

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