메뉴 건너뛰기




Volumn 250, Issue 1-2, 2006, Pages 124-132

GABAA-receptor mRNA expression in the prefrontal and temporal cortex of ALS patients

Author keywords

Amyotrophic laterals sclerosis; Extramotor brain regions; GABAA receptors; In situ hybridization histochemistry; Inhibitory neurotransmission

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMATE DECARBOXYLASE; MESSENGER RNA; RECEPTOR SUBUNIT;

EID: 33750509375     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2006.08.005     Document Type: Article
Times cited : (29)

References (46)
  • 1
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 6415 (1993) 59-62
    • (1993) Nature , vol.362 , Issue.6415 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5    Hentati, A.6
  • 2
    • 0030479608 scopus 로고    scopus 로고
    • Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study
    • Abrahams S., Goldstein L.H., Kew J.J., Brooks D.J., Lloyd C.M., Frith C.D., et al. Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study. Brain 119 Pt 6 (1996) 2105-2120
    • (1996) Brain , vol.119 , Issue.PART 6 , pp. 2105-2120
    • Abrahams, S.1    Goldstein, L.H.2    Kew, J.J.3    Brooks, D.J.4    Lloyd, C.M.5    Frith, C.D.6
  • 3
    • 0033765916 scopus 로고    scopus 로고
    • Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil
    • Lloyd C.M., Richardson M.P., Brooks D.J., Al Chalabi A., and Leigh P.N. Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil. Brain 123 Pt 11 (2000) 2289-2296
    • (2000) Brain , vol.123 , Issue.PART 11 , pp. 2289-2296
    • Lloyd, C.M.1    Richardson, M.P.2    Brooks, D.J.3    Al Chalabi, A.4    Leigh, P.N.5
  • 5
    • 16844381835 scopus 로고    scopus 로고
    • Cognitive change in ALS: a prospective study
    • Abrahams S., Leigh P.N., and Goldstein L.H. Cognitive change in ALS: a prospective study. Neurology 64 7 (2005) 1222-1226
    • (2005) Neurology , vol.64 , Issue.7 , pp. 1222-1226
    • Abrahams, S.1    Leigh, P.N.2    Goldstein, L.H.3
  • 6
    • 0024592522 scopus 로고
    • Neuropsychological, electroencephalogram and brain computed tomography findings in motor neuron disease
    • Gallassi R., Montagna P., Morreale A., Lorusso S., Tinuper P., Daidone R., et al. Neuropsychological, electroencephalogram and brain computed tomography findings in motor neuron disease. Eur Neurol 29 2 (1989) 115-120
    • (1989) Eur Neurol , vol.29 , Issue.2 , pp. 115-120
    • Gallassi, R.1    Montagna, P.2    Morreale, A.3    Lorusso, S.4    Tinuper, P.5    Daidone, R.6
  • 7
    • 0027283420 scopus 로고
    • Cortical function in amyotrophic lateral sclerosis. A positron emission tomography study
    • Kew J.J., Leigh P.N., Playford E.D., Passingham R.E., Goldstein L.H., Frackowiak R.S., et al. Cortical function in amyotrophic lateral sclerosis. A positron emission tomography study. Brain 116 Pt 3 (1993) 655-680
    • (1993) Brain , vol.116 , Issue.PART 3 , pp. 655-680
    • Kew, J.J.1    Leigh, P.N.2    Playford, E.D.3    Passingham, R.E.4    Goldstein, L.H.5    Frackowiak, R.S.6
  • 8
    • 0026515287 scopus 로고
    • Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study
    • Ludolph A.C., Langen K.J., Regard M., Herzog H., Kemper B., Kuwert T., et al. Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study. Acta Neurol Scand 85 2 (1992) 81-89
    • (1992) Acta Neurol Scand , vol.85 , Issue.2 , pp. 81-89
    • Ludolph, A.C.1    Langen, K.J.2    Regard, M.3    Herzog, H.4    Kemper, B.5    Kuwert, T.6
  • 10
    • 0034326242 scopus 로고    scopus 로고
    • Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS)
    • Neary D., Snowden J.S., and Mann D.M. Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS). J Neurol Sci 180 1-2 (2000) 15-20
    • (2000) J Neurol Sci , vol.180 , Issue.1-2 , pp. 15-20
    • Neary, D.1    Snowden, J.S.2    Mann, D.M.3
  • 12
    • 0036570159 scopus 로고    scopus 로고
    • Oxidatively modified proteins in aging and disease
    • Beal M.F. Oxidatively modified proteins in aging and disease. Free Radic Biol Med 32 9 (2002) 797-803
    • (2002) Free Radic Biol Med , vol.32 , Issue.9 , pp. 797-803
    • Beal, M.F.1
  • 13
    • 3943102116 scopus 로고    scopus 로고
    • Unraveling the mechanisms involved in motor neuron degeneration in ALS
    • Bruijn L.I., Miller T.M., and Cleveland D.W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 27 (2004) 723-749
    • (2004) Annu Rev Neurosci , vol.27 , pp. 723-749
    • Bruijn, L.I.1    Miller, T.M.2    Cleveland, D.W.3
  • 14
    • 0035978743 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis
    • Rowland L.P., and Shneider N.A. Amyotrophic lateral sclerosis. N Engl J Med 344 22 (2001) 1688-1700
    • (2001) N Engl J Med , vol.344 , Issue.22 , pp. 1688-1700
    • Rowland, L.P.1    Shneider, N.A.2
  • 15
    • 17444367702 scopus 로고    scopus 로고
    • Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis
    • Kiaei M., Kipiani K., Petri S., Choi D.K., Chen J., Calingasan N.Y., et al. Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem 93 2 (2005) 403-411
    • (2005) J Neurochem , vol.93 , Issue.2 , pp. 403-411
    • Kiaei, M.1    Kipiani, K.2    Petri, S.3    Choi, D.K.4    Chen, J.5    Calingasan, N.Y.6
  • 16
    • 25444522220 scopus 로고    scopus 로고
    • Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis
    • Sargsyan S.A., Monk P.N., and Shaw P.J. Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis. Glia 51 4 (2005) 241-253
    • (2005) Glia , vol.51 , Issue.4 , pp. 241-253
    • Sargsyan, S.A.1    Monk, P.N.2    Shaw, P.J.3
  • 17
    • 23844538993 scopus 로고    scopus 로고
    • The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?
    • Strong M.J., Kesavapany S., and Pant H.C. The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?. J Neuropathol Exp Neurol 64 8 (2005) 649-664
    • (2005) J Neuropathol Exp Neurol , vol.64 , Issue.8 , pp. 649-664
    • Strong, M.J.1    Kesavapany, S.2    Pant, H.C.3
  • 18
    • 33750524554 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and amyotrophic lateral sclerosis
    • Hervias I., Beal M.F., and Manfredi G. Mitochondrial dysfunction and amyotrophic lateral sclerosis. Muscle Nerve (2005)
    • (2005) Muscle Nerve
    • Hervias, I.1    Beal, M.F.2    Manfredi, G.3
  • 19
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1 8 (1988) 623-634
    • (1988) Neuron , vol.1 , Issue.8 , pp. 623-634
    • Choi, D.W.1
  • 20
    • 0036787803 scopus 로고    scopus 로고
    • Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
    • Heath P.R., and Shaw P.J. Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis. Muscle Nerve 26 4 (2002) 438-458
    • (2002) Muscle Nerve , vol.26 , Issue.4 , pp. 438-458
    • Heath, P.R.1    Shaw, P.J.2
  • 21
    • 30344437262 scopus 로고    scopus 로고
    • Glutamate AMPA receptors change in motor neurons of SOD1(G93A) transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amyotrophic lateral sclerosis-like disease
    • Tortarolo M., Grignaschi G., Calvaresi N., Zennaro E., Spaltro G., Colovic M., et al. Glutamate AMPA receptors change in motor neurons of SOD1(G93A) transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amyotrophic lateral sclerosis-like disease. J Neurosci Res 83 1 (2006) 134-146
    • (2006) J Neurosci Res , vol.83 , Issue.1 , pp. 134-146
    • Tortarolo, M.1    Grignaschi, G.2    Calvaresi, N.3    Zennaro, E.4    Spaltro, G.5    Colovic, M.6
  • 23
    • 0028338548 scopus 로고
    • Impact of beta and gamma variants on ligand-binding properties of gamma-aminobutyric acid type A receptors
    • Luddens H., Seeburg P.H., and Korpi E.R. Impact of beta and gamma variants on ligand-binding properties of gamma-aminobutyric acid type A receptors. Mol Pharmacol 45 5 (1994) 810-814
    • (1994) Mol Pharmacol , vol.45 , Issue.5 , pp. 810-814
    • Luddens, H.1    Seeburg, P.H.2    Korpi, E.R.3
  • 24
    • 0028978201 scopus 로고
    • Heterogeneity of GABAA-receptors: cell-specific expression, pharmacology, and regulation
    • Mohler H., Knoflach F., Paysan J., Motejlek K., Benke D., Luscher B., et al. Heterogeneity of GABAA-receptors: cell-specific expression, pharmacology, and regulation. Neurochem Res 20 5 (1995) 631-636
    • (1995) Neurochem Res , vol.20 , Issue.5 , pp. 631-636
    • Mohler, H.1    Knoflach, F.2    Paysan, J.3    Motejlek, K.4    Benke, D.5    Luscher, B.6
  • 26
    • 0027764618 scopus 로고
    • The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study
    • Kew J.J., Goldstein L.H., Leigh P.N., Abrahams S., Cosgrave N., Passingham R.E., et al. The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study. Brain 116 Pt 6 (1993) 1399-1423
    • (1993) Brain , vol.116 , Issue.PART 6 , pp. 1399-1423
    • Kew, J.J.1    Goldstein, L.H.2    Leigh, P.N.3    Abrahams, S.4    Cosgrave, N.5    Passingham, R.E.6
  • 27
    • 0031799363 scopus 로고    scopus 로고
    • International Union of Pharmacology: XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function
    • Barnard E.A., Skolnick P., Olsen R.W., Mohler H., Sieghart W., Biggio G., et al. International Union of Pharmacology: XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacol Rev 50 2 (1998) 291-313
    • (1998) Pharmacol Rev , vol.50 , Issue.2 , pp. 291-313
    • Barnard, E.A.1    Skolnick, P.2    Olsen, R.W.3    Mohler, H.4    Sieghart, W.5    Biggio, G.6
  • 29
    • 0028971245 scopus 로고
    • GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls
    • Akbarian S., Huntsman M.M., Kim J.J., Tafazzoli A., Potkin S.G., Bunney Jr. W.E., et al. GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls. Cereb Cortex 5 6 (1995) 550-560
    • (1995) Cereb Cortex , vol.5 , Issue.6 , pp. 550-560
    • Akbarian, S.1    Huntsman, M.M.2    Kim, J.J.3    Tafazzoli, A.4    Potkin, S.G.5    Bunney Jr., W.E.6
  • 30
    • 0030512464 scopus 로고    scopus 로고
    • Motor neurone disease-inclusion dementia
    • Jackson M., Lennox G., and Lowe J. Motor neurone disease-inclusion dementia. Neurodegeneration 5 4 (1996) 339-350
    • (1996) Neurodegeneration , vol.5 , Issue.4 , pp. 339-350
    • Jackson, M.1    Lennox, G.2    Lowe, J.3
  • 31
    • 3142628291 scopus 로고    scopus 로고
    • Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study
    • Abrahams S., Goldstein L.H., Simmons A., Brammer M., Williams S.C., Giampietro V., et al. Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain 127 Pt 7 (2004) 1507-1517
    • (2004) Brain , vol.127 , Issue.PART 7 , pp. 1507-1517
    • Abrahams, S.1    Goldstein, L.H.2    Simmons, A.3    Brammer, M.4    Williams, S.C.5    Giampietro, V.6
  • 32
    • 0028092904 scopus 로고
    • Frontal lobe atrophy in motor neuron diseases
    • Kiernan J.A., and Hudson A.J. Frontal lobe atrophy in motor neuron diseases. Brain 117 Pt 4 (1994) 747-757
    • (1994) Brain , vol.117 , Issue.PART 4 , pp. 747-757
    • Kiernan, J.A.1    Hudson, A.J.2
  • 33
    • 0029000507 scopus 로고
    • A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis
    • Abrahams S., Leigh P.N., Kew J.J., Goldstein L.H., Lloyd C.M., and Brooks D.J. A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis. J Neurol Sci 129 Suppl (1995) 44-46
    • (1995) J Neurol Sci , vol.129 , Issue.SUPPL , pp. 44-46
    • Abrahams, S.1    Leigh, P.N.2    Kew, J.J.3    Goldstein, L.H.4    Lloyd, C.M.5    Brooks, D.J.6
  • 34
    • 0032905779 scopus 로고    scopus 로고
    • Selective attention is impaired in amyotrophic lateral sclerosis-a study of event-related EEG potentials
    • Vieregge P., Wauschkuhn B., Heberlein I., Hagenah J., and Verleger R. Selective attention is impaired in amyotrophic lateral sclerosis-a study of event-related EEG potentials. Brain Res Cogn Brain Res 8 1 (1999) 27-35
    • (1999) Brain Res Cogn Brain Res , vol.8 , Issue.1 , pp. 27-35
    • Vieregge, P.1    Wauschkuhn, B.2    Heberlein, I.3    Hagenah, J.4    Verleger, R.5
  • 35
    • 0026341587 scopus 로고
    • Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study
    • Waldemar G., Vorstrup S., Jensen T.S., Johnsen A., and Boysen G. Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study. J Neurol Sci 107 1 (1992) 19-28
    • (1992) J Neurol Sci , vol.107 , Issue.1 , pp. 19-28
    • Waldemar, G.1    Vorstrup, S.2    Jensen, T.S.3    Johnsen, A.4    Boysen, G.5
  • 36
    • 1842471942 scopus 로고    scopus 로고
    • Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
    • Turner M.R., Cagnin A., Turkheimer F.E., Miller C.C., Shaw C.E., Brooks D.J., et al. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis 15 3 (2004) 601-609
    • (2004) Neurobiol Dis , vol.15 , Issue.3 , pp. 601-609
    • Turner, M.R.1    Cagnin, A.2    Turkheimer, F.E.3    Miller, C.C.4    Shaw, C.E.5    Brooks, D.J.6
  • 38
    • 0033974104 scopus 로고    scopus 로고
    • Pharmacologic reversal of cortical hyperexcitability in patients with ALS
    • Caramia M.D., Palmieri M.G., Desiato M.T., Iani C., Scalise A., Telera S., et al. Pharmacologic reversal of cortical hyperexcitability in patients with ALS. Neurology 54 1 (2000) 58-64
    • (2000) Neurology , vol.54 , Issue.1 , pp. 58-64
    • Caramia, M.D.1    Palmieri, M.G.2    Desiato, M.T.3    Iani, C.4    Scalise, A.5    Telera, S.6
  • 39
    • 0035965267 scopus 로고    scopus 로고
    • Subunit arrangement of gamma-aminobutyric acid type A receptors
    • Baumann S.W., Baur R., and Sigel E. Subunit arrangement of gamma-aminobutyric acid type A receptors. J Biol Chem 276 39 (2001) 36275-36280
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36275-36280
    • Baumann, S.W.1    Baur, R.2    Sigel, E.3
  • 40
    • 0035575860 scopus 로고    scopus 로고
    • Alternate use of distinct intersubunit contacts controls GABAA receptor assembly and stoichiometry
    • Klausberger T., Sarto I., Ehya N., Fuchs K., Furtmuller R., Mayer B., et al. Alternate use of distinct intersubunit contacts controls GABAA receptor assembly and stoichiometry. J Neurosci 21 23 (2001) 9124-9133
    • (2001) J Neurosci , vol.21 , Issue.23 , pp. 9124-9133
    • Klausberger, T.1    Sarto, I.2    Ehya, N.3    Fuchs, K.4    Furtmuller, R.5    Mayer, B.6
  • 41
    • 0028981088 scopus 로고
    • Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes
    • Sieghart W. Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. Pharmacol Rev 47 2 (1995) 181-234
    • (1995) Pharmacol Rev , vol.47 , Issue.2 , pp. 181-234
    • Sieghart, W.1
  • 43
    • 0029174650 scopus 로고
    • Structure and pharmacology of vertebrate GABAA receptor subtypes
    • Whiting P.J., McKernan R.M., and Wafford K.A. Structure and pharmacology of vertebrate GABAA receptor subtypes. Int Rev Neurobiol 38 (1995) 95-138
    • (1995) Int Rev Neurobiol , vol.38 , pp. 95-138
    • Whiting, P.J.1    McKernan, R.M.2    Wafford, K.A.3
  • 44
    • 0027210116 scopus 로고
    • Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease
    • Ince P., Stout N., Shaw P., Slade J., Hunziker W., Heizmann C.W., et al. Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease. Neuropathol Appl Neurobiol 19 4 (1993) 291-299
    • (1993) Neuropathol Appl Neurobiol , vol.19 , Issue.4 , pp. 291-299
    • Ince, P.1    Stout, N.2    Shaw, P.3    Slade, J.4    Hunziker, W.5    Heizmann, C.W.6
  • 45
    • 0033981257 scopus 로고    scopus 로고
    • Unchanged total number of neurons in motor cortex and neocortex in amyotrophic lateral sclerosis: a stereological study
    • Gredal O., Pakkenberg H., Karlsborg M., and Pakkenberg B. Unchanged total number of neurons in motor cortex and neocortex in amyotrophic lateral sclerosis: a stereological study. J Neurosci Methods 95 2 (2000) 171-176
    • (2000) J Neurosci Methods , vol.95 , Issue.2 , pp. 171-176
    • Gredal, O.1    Pakkenberg, H.2    Karlsborg, M.3    Pakkenberg, B.4
  • 46
    • 0028948389 scopus 로고
    • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
    • Akbarian S., Kim J.J., Potkin S.G., Hagman J.O., Tafazzoli A., Bunney Jr. W.E., et al. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry 52 4 (1995) 258-266
    • (1995) Arch Gen Psychiatry , vol.52 , Issue.4 , pp. 258-266
    • Akbarian, S.1    Kim, J.J.2    Potkin, S.G.3    Hagman, J.O.4    Tafazzoli, A.5    Bunney Jr., W.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.