Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells

FEBS Letters

Volumn 588, Issue 11, 2014, Pages 2016-2024

  Liu, Lu ^a   Chowdhury, Subrata ^a   Fang, Xin ^a   Liu, Jun Li ^a   Srikant, Coimbatore B ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Apoptosis; ER stress; Glucose regulated peptide 78; mTORC1; siRNA interference; Unfolded protein response

Indexed keywords

G PROTEIN BETA SUBUNIT LIKE PROTEIN; GLUCOSE REGULATED PROTEIN 78; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN; PROTEIN KINASE B; RAPTOR PROTEIN; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE; GENE OVEREXPRESSION; INSULINOMA CELL LINE; MOUSE; MURINE REGENERATING 2 GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

MURINAE; RAPTORES;

APOPTOSIS; ER STRESS; GLUCOSE-REGULATED PEPTIDE 78; MTORC1; SIRNA INTERFERENCE; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HEAT-SHOCK PROTEINS; INSULINOMA; MICE; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSCRIPTIONAL ACTIVATION; UNFOLDED PROTEIN RESPONSE;

EID: 84901046839     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.04.030     Document Type: Article

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