Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response

Experimental Neurology

Volumn 237, Issue 2, 2012, Pages 396-406

  Camacho, Alberto ^a   Rodriguez Cuenca, Sergio ^a   Blount, Margaret ^a   Prieur, Xavier ^a   Barbarroja, Nuria ^a,b   Fuller, Maria ^d   Hardingham, Giles E ^c   Vidal Puig, Antonio ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

Amino acids; Brain; Endoplasmic reticulum stress; Mitochondria; MTOR; PGC 1 beta

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; THAPSIGARGIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN MITOCHONDRION; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; HYPOTHALAMUS; IN VITRO STUDY; LIPID DIET; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DIET; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN; DIET, HIGH-FAT; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANS-ACTIVATORS;

EID: 84864932595     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.06.031     Document Type: Article

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