Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes

Diabetes

Volumn 53, Issue 12, 2004, Pages 3131-3141

  Lu, Yarong ^a   Herrera, Pedro L ^b   Guo, Yubin ^a   Sun, David ^a   Tang, Zhengyi ^a   LeRoith, Derek ^c   Liu, Jun Li ^a,d,e  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d Shanghai Clin Ctr Endocr M D   (China)

^e ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; MESSENGER RNA; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR; STREPTOZOCIN; TRANSCRIPTION FACTOR PDX 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE; GENE INACTIVATION; GENETIC DISORDER; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN SENSITIVITY; INSULIN SYNTHESIS; LIPID DIET; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; FEMALE; GENE SILENCING; GLUCAGON; GLUCOSE TOLERANCE TEST; IMMUNITY, NATURAL; INSULIN; INSULIN-LIKE GROWTH FACTOR I; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED DBA; MICE, KNOCKOUT; PANCREAS;

EID: 9444293983     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.12.3131     Document Type: Article

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