Effects of soluble and insoluble fractions from bilberries, black currants, and raspberries on short-chain fatty acid formation, anthocyanin excretion, and cholesterol in rats

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 19, 2014, Pages 4359-4368

  Jakobsdottir, Greta ^a   Nilsson, Ulf ^a   Blanco, Narda ^b   Sterner, Olov ^b   Nyman, Margareta ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

anthocyanins; berries; cholesterol; fiber; SCFAs

Indexed keywords

BODY FLUIDS; CHAINS; CHOLESTEROL; FATTY ACIDS; FIBERS; FRUITS; PHYSIOLOGY; RATS; ANTHOCYANINS; BUTYRIC ACID; FLAVONOIDS;

BERRIES; BLACK CURRANT; DIETARY FIBERS; DISTAL COLONS; SCFAS; SHORT CHAIN FATTY ACIDS (SCFAS); SHORT-CHAIN FATTY ACIDS; CYANIDIN;

ANTHOCYANINS; FATTY ACIDS;

RATTUS; RIBES HUDSONIANUM; RUBUS GLAUCUS; VACCINIUM MYRTILLUS;

ANTHOCYANIN; CHOLESTEROL; PLANT EXTRACT; VOLATILE FATTY ACID;

ANIMAL; CHEMISTRY; COMPARATIVE STUDY; FRUIT; ISOLATION AND PURIFICATION; LIVER; MALE; METABOLISM; RAT; RIBES; RUBUS; SOLUBILITY; VACCINIUM MYRTILLUS; WISTAR RAT;

ANIMALS; ANTHOCYANINS; CHOLESTEROL; FATTY ACIDS, VOLATILE; FRUIT; LIVER; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; RIBES; RUBUS; SOLUBILITY; VACCINIUM MYRTILLUS;

EID: 84900793800     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf5007566     Document Type: Article

References (42)

1. Borges, G.; Degeneve, A.; Mullen, W. Identification of flavonoid and phenolic antioxidants in black currants, blueberries, raspberries, red currants, and cranberries J. Agric. Food Chem. 2010, 58, 3901-3909
2. Anderson, J. W.; Baird, P.; Davis, R. H., Jr. Health benefits of dietary fiber Nutr Rev. 2009, 67, 188-205
3. Lock, K.; Pomerleau, J.; Causer, L. The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet Bull. WHO 2005, 83, 100-108
4. de Mello, V. D. F.; Schwab, U.; Kolehminen, M. A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: the Sysdimet study Diabetologia 2011, 54, 2755-2767
5. Landete, J. M. Updated knowledge about polyphenols: functions, bioavailability, metabolism, and health Crit Rev. Food Sci. Nutr. 2012, 52, 936-948
6. Puupponen-Pimia, R.; Nohynek, L.; Meier, C. Antimicrobial properties of phenolic compounds from berries J. Appl. Microbiol. 2001, 90, 494-507
7. Wang, H.; Cao, G.; Prior, R. Oxygen radical absorbing capacity of anthocyanins J. Agric. Food Chem. 1997, 45, 304-309
8. Heinonen, M. Antioxidant activity and antimicorobial effects of berry phenolics-a Finnish perspective Mol. Nutr. Food Res. 2007, 51, 684-691
9. Wong, J. M.; de Souza, R.; Kendall, C. W. Colonic health: fermentation and short chain fatty acids J. Clin. Gastroenterol. 2006, 40, 235-243
10. Macfarlane, S.; Macfarlane, G. T. Regulation of short-chain fatty acid production Proc. Nutr. Soc. 2003, 62, 67-72
11. Macfarlane, G. T.; Macfarlane, S. Bacteria, colonic fermentation, and gastrointestinal health J. AOAC Int. 2012, 95, 50-60
12. Bach Knudsen, K. E.; Serena, A.; Canibe, N. New insight into butyrate metabolism Proc. Nutr. Soc. 2003, 62, 81-86
13. Scheppach, W.; Bartram, H. P.; Richter, F. Role of short-chain fatty acids in the prevention of colorectal cancer Eur. J. Cancer 1995, 31A, 1077-1080
14. Galisteo, M.; Duarte, J.; Zarzuelo, A. Effects of dietary fibers on disturbances clustered in the metabolic syndrome J. Nutr. Biochem. 2008, 19, 71-84
15. Lunn, J.; Buttriss, J. Carbohydrates and dietary fibre Nutr. Bull. 2007, 32, 21-64
16. Palafox-Carlos, H.; Ayala-Zavala, J. F.; Gonzalez-Aguilar, G. A. The role of dietary fiber in the bioaccessibility and bioavailability of fruit and vegetable antioxidants J. Food Sci. 2011, 76, R6-R15
17. Wawer, I.; Wolniak, M.; Paradowska, K. Solid state NMR study of dietary fiber powders from aronia, bilberry, black currant and apple Solid State Nucl. Magn. Reson. 2006, 30, 106-113
18. Theander, O.; Åman, P.; Westerlund, E. Total dietary fiber determined as neutral sugar residues, uronic acid residues, and Klason lignin (the Uppsala method): collaborative study J. AOAC Int. 1995, 78, 1030-1044
19. Asp, N. G.; Johansson, C. G.; Hallmer, H. Rapid enzymatic assay of insoluble and soluble dietary fiber J. Agric. Food Chem. 1983, 31, 476-482
20. Björck, I.; Nyman, E. M.; Pedersen, B. Formation of enzyme resistant starch during autoclaving of wheat starch: studies in vitro and in vivo J. Cereal Sci. 1987, 6, 159-172
21. Animal Specific Training: Rats. University of Wisconsin-Milwaukee, USA; http://www4.uwm.edu/usa/acp/training/manual/manual-rats.cfm (accessed January 22, 2014).
22. Nyman, M.; Asp, N. G. Fermentation of dietary fibre components in the rat intestinal tract Br. J. Nutr. 1982, 47, 357-366
23. Zhao, G.; Liu, J. F.; Nyman, M. Determination of short-chain fatty acids in serum by hollow fiber supported liquid membrane extraction coupled with gas chromatography J. Chromatogr. 2007, 846, 202-208
24. Nyman, M.; Björck, I.; Siljeström, M.; Dietary fibre in cereals-composition, fermentation and effect of processing. In Proceedings from an International Symposium in Cereal Science and Technology in Sweden, June 13-16, 1988; Asp, N. G., Ed.; Lund University BTJ tryck: Lund, Sweden, 1989; pp 40-54.
25. Jakobsdottir, G.; Jädert, C.; Holm, L. Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum Br. J. Nutr. 2013, 110, 1565-1572
26. Zhao, G.; Nyman, M.; Jönsson, J. A. Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography Biomed. Chromatogr. 2006, 20, 674-682
27. Jakobsdottir, G.; Blanco, N.; Xu, J.; Formation of short-chain fatty acids, excretion of anthocyanins, and microbial diversity in rats fed blackcurrants, blackberries, and raspberries. J. Nutr. Metab. 2013, DOI: 10.1155/2013/202534.
28. Wu, X.; Gu, L.; Prior, R. L. Characterization of anthocyanins and proanthocyanidins in some cultivars of Ribes, Aronia, and Sambucus and their antioxidant capacity J. Agric. Food Chem. 2004, 52, 7846-7856
29. Ogawa, K.; Sakakibara, H.; Iwata, R. Anthocyanin composition and antioxidant activity of the vrowberry (Empetrum nigrum) and other berries J. Agric. Food Chem. 2008, 56, 4457-4462
30. Mullen, W.; Larcombe, S.; Arnold, K. Use of accurate mass full scan mass spectrometry for the analysis of anthocyanins in berries and berry-fed tissues J. Agric. Food Chem. 2010, 58, 3910-3915
31. Kim, B.; Ku, C. S.; Pham, T. X. Aronia melanocarpa (chokeberry) polyphenol-rich extract improves antioxidant function and reduces total plasma cholesterol in apolipoprotein E knockout mice Nutr. Res. (N.Y.) 2013, 33, 406-413
32. Felgines, C.; Talavera, S.; Texier, O. Blackberry anthocyanins are mainly recovered from urine as mthylated and glucuronidated conjugates in humans J. Agric. Food Chem. 2005, 53, 7721-7727
33. Fleshhut, J.; Kratzer, F.; Rechkemmer, G. Stability and biotransformation of various dietary anthocyanins in vitro Eur. J. Nutr. 2006, 45, 7-18
34. McGhie, T. K.; Walton, M. C. The bioavailability and absorption of anthocyanins: towards a better understanding Mol. Nutr. Food Res. 2007, 51, 702-713
35. Bäckhed, F.; Ding, H.; Wang, T. The gut microbiota as an environmental factor that regulates fat storage Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 15718-15723
36. Ekström, L. M.; Björck, I. M.; Östman, E. M. On the possibility to affect the course of glycaemia, insulinaemia, and perceived hunger/satiety to bread meals in healthy volunteers Food Funct. 2013, 4, 522-529
37. Haska, L.; Andersson, R.; Nyman, M. The effect of dietary fiber from wheat processing streams on the formation of carboxylic acids and microbiota in the hindgut of rats J. Agric. Food Chem. 2011, 59, 3406-3413
38. Berggren, A. M.; Nyman, E. M.; Lundquist, I. Influence of orally and rectally administered propionate on cholesterol and glucose metabolism in obese rats Br. J. Nutr. 1996, 76, 287-294
39. Marcil, V.; Delvin, E.; Garofalo, C. Butyrate impairs lipid transport by inhibiting microsomal triglyceride transfer protein in Caco-2 cells J. Nutr. 2003, 133, 2180-2183
40. Jakobsdottir, G.; Xu, J.; Molin, G. High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects PLoS One 2013, 13, 8-11
41. Nilsson, U.; Nyman, E. M. Carboxylic acids in the hindgut of rats fed higly soluble inulin and Bifidobacterium lactis (Bb-123), Lactobacillus salivarius (UCC 500) or Lactobacillus rhamnous (GG) Scand. J. Food Nutr. 2007, 51, 13-21
42. Berggren, A.; Björck, I. M. E.; Nyman, M. Short-chain fatty acid content and pH in caecum of rats given various sources of carbohydrates J. Sci. Food Agric. 1993, 63, 397-406