Optimizing cationic and neutral lipids for efficient gene delivery at high serum content

Journal of Gene Medicine

Volumn 16, Issue 3-4, 2014, Pages 84-96

  Chan, Chia Ling ^a,b   Ewert, Kai K ^a   Majzoub, Ramsey N ^a   Hwu, Yeu Kuang ^b   Liang, Keng S ^c,d   Leal, Cecília ^a,e   Safinya, Cyrus R ^a  

^a University of California   (United States)

^b INSTITUTE OF PHYSICS   (Taiwan)

^c NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

^d NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^e University of Illinois at Urbana Champaign   (United States)

Author keywords

Cationic liposomes; Gene delivery; Glycerol monooleate; Multivalent cationic lipid; Serum

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; DIOLEOYLPHOSPHATIDYLCHOLINE; DNA; GLYCEROL OLEATE; LIPID; LIPOFECTAMINE; LIPOSOME; 1,2-DIOLEOYLOXY-3-(TRIMETHYLAMMONIUM)PROPANE; BENZAMIDE DERIVATIVE; CATION; MONOUNSATURATED FATTY ACID; N1-(2-(1-((3-AMINOPROPYL)AMINO)-4-(DI-(3-AMINOPROPYL)AMINO)BUTYLCARBOXAMIDO)ETHYL)-3,4-DI-(OLEYLOXY)BENZAMIDE; QUATERNARY AMMONIUM DERIVATIVE; SPERMINE;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; L CELL LINE; LIPID BLOOD LEVEL; LIPID COMPOSITION; LIPOGENESIS; LIPOSOMAL GENE DELIVERY SYSTEM; MELANOMA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; ANALOGS AND DERIVATIVES; CHEMISTRY; ESCHERICHIA COLI; GENE THERAPY; GENE TRANSFER; GENETICS; PLASMID; PROCEDURES; SERUM; TUMOR CELL LINE;

BENZAMIDES; CATIONS; CELL LINE, TUMOR; DNA; ESCHERICHIA COLI; FATTY ACIDS, MONOUNSATURATED; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; LIPIDS; LIPOSOMES; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; SERUM; SPERMINE; TRANSFECTION;

EID: 84900419358     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2762     Document Type: Article

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