Anionic polyethyleneglycol lipids added to cationic lipoplexes increase their plasmatic circulation time

Journal of Controlled Release

Volumn 88, Issue 3, 2003, Pages 429-443

  Nicolazzi, Céline ^a   Mignet, Nathalie ^a,b   De La Figuera, Natalia ^a   Cadet, Mamonjy ^a   Ibad, Raoul Torero ^a   Seguin, Johanne ^a   Scherman, Daniel ^a,b   Bessodes, Michel ^a  

^a SANOFI   (France)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

Anionic PEG; Colloidal stabilization; Gene delivery; Lipoplex; Tumor delivery

Indexed keywords

COLLOIDS; DNA; ELECTRIC CHARGE; ELECTROSTATICS; POLYETHYLENE GLYCOLS; TUMORS;

CATIONIC LIPOPLEXES;

LIPIDS;

ALPHA METHOXY EPSILON [2 AMINO N [[[(DIOCTADECYLCARBAMOYLMETHYLCARBAMOYL)METHYL]CARBAMOYL]METHYL]ACETAMIDE]POLYET HYLENE GLYCOL; ALPHA METHOXY EPSILON [3 (AMINO 2 CARBOXYPROPIONYLAMINO) N [(DIOCTADECYLCARBAMOYLMETHYLCARBAMOYL)METHYL]SUCCINAMIC ACID]POLYETHYLENE GLYCOL; ALPHA METHOXY EPSILON [3 AMINO N [(DIOCTADECYLCARBAMOYLMETHYLCARBAMOYL)METHYL]SUCCINAMIC ACID]POLYETHYLENE GLYCOL; ALPHA METHOXY EPSILON [4 AMINO 4 [2 CARBOXY 1 [[(DIOCTADECYLCARBAMOYLMETHYLCARBAMOYL)METHYL]CARBAMOYL]ETHYLCARBAMOYL]BUTYRIC ACID]POLYETHYLENE GLYCOL; CHLORAMPHENICOL ACETYLTRANSFERASE; LIPID; LIPOPLEX; LIPOSOME; MACROGOL; PLASMID DNA; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER THERAPY; CIRCULATION; COLLOID; CONTROLLED STUDY; DNA TRANSFER; DRUG BIOAVAILABILITY; DRUG DEGRADATION; DRUG STABILITY; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; VIRAL GENE DELIVERY SYSTEM; ZETA POTENTIAL;

EID: 0037467212     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00067-1     Document Type: Article

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