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Volumn 364, Issue 1847, 2006, Pages 2573-2596

Cationic liposome-DNA complexes: From liquid crystal science to gene delivery applications

Author keywords

Cationic liposomes; Gene delivery; Gene therapy; Liquid crystal phases; Synchrotron X ray scattering; Transfection efficiency

Indexed keywords


EID: 33750515643     PISSN: 1364503X     EISSN: None     Source Type: Journal    
DOI: 10.1098/rsta.2006.1841     Document Type: Article
Times cited : (68)

References (68)
  • 1
    • 12244291636 scopus 로고    scopus 로고
    • New multivalent lipids reveal bell-curve for transfection versus membrane charge density: Lipid-DNA complexes for gene delivery
    • Ahmad, A., Evans, H., Ewert, K., George, C. X., Samuel, C. E. & Safinya, C. R. 2005 New multivalent lipids reveal bell-curve for transfection versus membrane charge density: lipid-DNA complexes for gene delivery. J. Genet. Med. 7, 739-748.
    • (2005) J. Genet. Med. , vol.7 , pp. 739-748
    • Ahmad, A.1    Evans, H.2    Ewert, K.3    George, C.X.4    Samuel, C.E.5    Safinya, C.R.6
  • 2
    • 0031642993 scopus 로고    scopus 로고
    • Electrostatics of DNA cationic lipid complexes: Isoelectric instability
    • doi:10.1007/s100510050353
    • Bruinsma, R. 1998 Electrostatics of DNA cationic lipid complexes: isoelectric instability. Eur. Phys. J. B 4, 75-88. (doi:10.1007/s100510050353)
    • (1998) Eur. Phys. J. B , vol.4 , pp. 75-88
    • Bruinsma, R.1
  • 3
    • 0036190843 scopus 로고    scopus 로고
    • Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems
    • doi:10.1038/sj.gt.3301635
    • Cartier, R. & Reszka, R. 2002 Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems. Gene Ther. 9, 157-167. (doi:10.1038/sj.gt.3301635)
    • (2002) Gene Ther. , vol.9 , pp. 157-167
    • Cartier, R.1    Reszka, R.2
  • 4
    • 0034724857 scopus 로고    scopus 로고
    • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
    • doi:10.1126/science.288.5466.669
    • Cavazzana-Calvo, M. et al. 2000 Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288, 669-672. (doi:10.1126/science. 288.5466.669)
    • (2000) Science , vol.288 , pp. 669-672
    • Cavazzana-Calvo, M.1
  • 5
    • 0033902946 scopus 로고    scopus 로고
    • Structure and function of lipid-DNA complexes for gene delivery
    • doi:10.1146/annurev.biophys.29.1.27
    • Chesnoy, S. & Huang, L. 2000 Structure and function of lipid-DNA complexes for gene delivery. Annu. Rev. Biophys. Biomol. Struct. 29, 27-47. (doi:10.1146/annurev.biophys.29.1.27)
    • (2000) Annu. Rev. Biophys. Biomol. Struct. , vol.29 , pp. 27-47
    • Chesnoy, S.1    Huang, L.2
  • 6
    • 0032965398 scopus 로고    scopus 로고
    • Cationic lipid-mediated gene transfer: Current concepts
    • Clark, P. R. & Hersh, E. M. 1999 Cationic lipid-mediated gene transfer: current concepts. Curr. Opin. Mol. Ther. 1, 158-176.
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , pp. 158-176
    • Clark, P.R.1    Hersh, E.M.2
  • 7
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004 - An overview
    • Edelstein, M. L., Abedi, M. R., Wixon, J. & Edelstein, R. M. 2004 Gene therapy clinical trials worldwide 1989-2004 - an overview. J. Genet. Med. 6, 597-602.
    • (2004) J. Genet. Med. , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 8
    • 0347926089 scopus 로고    scopus 로고
    • NLS bioconjugates for targeting therapeutic genes to the nucleus
    • doi:10.1016/S0169-409X(02)00184-9
    • Escriou, V., Carriere, M., Scherman, D. & Wils, P. 2003 NLS bioconjugates for targeting therapeutic genes to the nucleus. Adv. Drug Deliv. Rev. 55, 295-306. (doi:10.1016/S0169-409X(02)00184-9)
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 295-306
    • Escriou, V.1    Carriere, M.2    Scherman, D.3    Wils, P.4
  • 9
    • 0037038309 scopus 로고    scopus 로고
    • Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery
    • doi:10.1021/jm020233w
    • Ewert, K., Ahmad, A., Evans, H. M., Schmidt, H.-W. & Safinya, C. R. 2002 Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery. J. Med. Chem. 45, 5023-5029. (doi:10.1021/jm020233w)
    • (2002) J. Med. Chem. , vol.45 , pp. 5023-5029
    • Ewert, K.1    Ahmad, A.2    Evans, H.M.3    Schmidt, H.-W.4    Safinya, C.R.5
  • 10
    • 1642503835 scopus 로고    scopus 로고
    • Cationic lipid-DNA complexes for gene therapy: Understanding the relationship between complex structure and gene delivery pathways at the molecular level
    • doi:10.2174/0929867043456160
    • Ewert, K., Slack, N. L., Ahmad, A., Evans, H. M., Lin, A. J., Samuel, C. E. & Safinya, C. R. 2004 Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level. Curr. Med. Chem. 11, 133-149. (doi:10.2174/0929867043456160)
    • (2004) Curr. Med. Chem. , vol.11 , pp. 133-149
    • Ewert, K.1    Slack, N.L.2    Ahmad, A.3    Evans, H.M.4    Lin, A.J.5    Samuel, C.E.6    Safinya, C.R.7
  • 11
    • 12244265493 scopus 로고    scopus 로고
    • Cationic lipid-DNA complexes for non-viral gene therapy: Relating supramolecular structures to cellular pathways
    • doi:10.1517/14712598.5.1.33
    • Ewert, K., Ahmad, A., Evans, H. M. & Safinya, C. R. 2005a Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways. Expert Opin. Biol. Ther. 5, 33-53. (doi:10.1517/14712598.5.1.33)
    • (2005) Expert Opin. Biol. Ther. , vol.5 , pp. 33-53
    • Ewert, K.1    Ahmad, A.2    Evans, H.M.3    Safinya, C.R.4
  • 12
    • 33645236403 scopus 로고    scopus 로고
    • Lipoplex structures and their distinct cellular pathways
    • Non-viral vectors for gene therapy (ed. L. Huang, M.-C. Hung & E. Wagner), 2nd edn. San Diego, CA: Elsevier Inc.
    • Ewert, K., Ahmad, A., Evans, H. M., Slack, N. L., Lin, A. J., Martin-Herranz, A. & Safinya, C. R. 2005b Lipoplex structures and their distinct cellular pathways. In Non-viral vectors for gene therapy (ed. L. Huang, M.-C. Hung & E. Wagner), 2nd edn. Advances in genetics, vol. 53. San Diego, CA: Elsevier Inc.
    • (2005) Advances in Genetics , vol.53
    • Ewert, K.1    Ahmad, A.2    Evans, H.M.3    Slack, N.L.4    Lin, A.J.5    Martin-Herranz, A.6    Safinya, C.R.7
  • 13
    • 0029067792 scopus 로고
    • The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
    • doi:10.1016/0005-2736(95)80016-9
    • Farhood, H., Serbina, N. & Huang, L. 1995 The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim. Biophys. Acta 1235, 289-295. (doi:10.1016/0005-2736(95)80016-9)
    • (1995) Biochim. Biophys. Acta , vol.1235 , pp. 289-295
    • Farhood, H.1    Serbina, N.2    Huang, L.3
  • 14
    • 0026430686 scopus 로고
    • Gene therapeutics
    • doi:10.1038/349351a0
    • Feigner, P. L. & Rhodes, G. 1991 Gene therapeutics. Nature 349, 351-352. (doi:10.1038/349351a0)
    • (1991) Nature , vol.349 , pp. 351-352
    • Feigner, P.L.1    Rhodes, G.2
  • 16
    • 0035941087 scopus 로고    scopus 로고
    • Gene therapy: Safer and virus-free?
    • doi:10.1126/science.294.5547.1638
    • Ferber, D. 2001 Gene therapy: safer and virus-free? Science 294, 1638-1642. (doi:10.1126/science.294.5547.1638)
    • (2001) Science , vol.294 , pp. 1638-1642
    • Ferber, D.1
  • 17
    • 0031159392 scopus 로고    scopus 로고
    • Overcoming the obstacles to gene therapy
    • Friedmann, T. 1997 Overcoming the obstacles to gene therapy. Sci. Am. 276, 96-101.
    • (1997) Sci. Am. , vol.276 , pp. 96-101
    • Friedmann, T.1
  • 18
    • 0037448352 scopus 로고    scopus 로고
    • A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
    • doi:10.1056/NEJM200301163480314
    • Hacein-Bey-Abina, S. et al. 2003a A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348, 255-256. (doi:10.1056/NEJM200301163480314)
    • (2003) N. Engl. J. Med. , vol.348 , pp. 255-256
    • Hacein-Bey-Abina, S.1
  • 19
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • doi:10.1126/science.1088547
    • Hacein-Bey-Abina, S. et al. 2003b LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302, 415-419. (doi:10.1126/science.1088547)
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1
  • 20
    • 0031807139 scopus 로고    scopus 로고
    • Structure, stability, and thermodynamics of lamellar DNA-lipid complexes
    • Harries, D., May, S., Gelbart, W. M. & Ben-Shaul, A. 1998 Structure, stability, and thermodynamics of lamellar DNA-lipid complexes. Biophys. J. 75, 159-173.
    • (1998) Biophys. J. , vol.75 , pp. 159-173
    • Harries, D.1    May, S.2    Gelbart, W.M.3    Ben-Shaul, A.4
  • 21
    • 0030910465 scopus 로고    scopus 로고
    • Formation of de novo centromeres and construction of first-generation human artificial microchromosomes
    • doi:10.1038/ng0497-345
    • Harrington, J. J., Van Bokkelen, G., Mays, R. W., Gustashaw, K. & Williard, H. F. 1997 Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat. Genet. 15, 345-355. (doi:10.1038/ng0497-345)
    • (1997) Nat. Genet. , vol.15 , pp. 345-355
    • Harrington, J.J.1    Van Bokkelen, G.2    Mays, R.W.3    Gustashaw, K.4    Williard, H.F.5
  • 22
    • 0038039166 scopus 로고    scopus 로고
    • Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: A promising way for non-viral gene therapy?
    • doi:10.1016/80248-4900(03)00007-8
    • Hebert, E. 2003 Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: a promising way for non-viral gene therapy? Biol. Cell 95, 59-68. (doi:10.1016/80248-4900(03)00007-8)
    • (2003) Biol. Cell , vol.95 , pp. 59-68
    • Hebert, E.1
  • 23
    • 0002265662 scopus 로고    scopus 로고
    • Gene delivery-without viruses
    • Henry, C. M. 2001 Gene delivery-without viruses. Chem. Eng. News 79, 35-41.
    • (2001) Chem. Eng. News , vol.79 , pp. 35-41
    • Henry, C.M.1
  • 24
    • 0004078385 scopus 로고    scopus 로고
    • Huang, L., Hung, M.-C. & Wagner, E. (eds). San Diego, CA: Academic Press
    • Huang, L., Hung, M.-C. & Wagner, E. (eds) 1999 Non-viral vectors for gene therapy. San Diego, CA: Academic Press.
    • (1999) Non-viral Vectors for Gene Therapy
  • 25
    • 84875834130 scopus 로고    scopus 로고
    • Non-viral vectors for gene therapy, 2nd edn
    • Huang, L., Hung, M.-C. & Wagner, E. (eds). San Diego, CA: Elsevier Inc.
    • Huang, L., Hung, M.-C. & Wagner, E. (eds) 2005 Non-viral vectors for gene therapy, 2nd edn. Advances in genetics, vol. 53. San Diego, CA: Elsevier Inc.
    • (2005) Advances in Genetics , vol.53
  • 26
    • 0344707080 scopus 로고    scopus 로고
    • The role of helper lipids in cationic liposome-mediated gene transfer
    • Hui, S., Langner, M., Zhao, Y., Ross, P., Hurley, E. & Chan, K. 1996 The role of helper lipids in cationic liposome-mediated gene transfer. Biophys. J. 71, 590-599.
    • (1996) Biophys. J. , vol.71 , pp. 590-599
    • Hui, S.1    Langner, M.2    Zhao, Y.3    Ross, P.4    Hurley, E.5    Chan, K.6
  • 27
    • 0031869439 scopus 로고    scopus 로고
    • Signals mediating nuclear targeting and their regulation: Application in drug delivery
    • doi:10.1002/(SICI)1098-1128(199807)18:4〈;189::AID-MED1〉3.0. CO;2-R
    • Jans, D. A., Chan, C. K. & Hübner, S. 1998 Signals mediating nuclear targeting and their regulation: application in drug delivery. Med. Res. Rev. 18, 189-223. (doi:10.1002/(SICI)1098-1128(199807)18:4〈;189::AID- MED1〉3.0.CO;2-R)
    • (1998) Med. Res. Rev. , vol.18 , pp. 189-223
    • Jans, D.A.1    Chan, C.K.2    Hübner, S.3
  • 28
    • 0032479572 scopus 로고    scopus 로고
    • An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery
    • doi:10.1126/science.281.5373.78
    • Koltover, I., Salditt, T., Rädler, J. O. & Safinya, C. R. 1998 An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 281, 78-81, (doi:10.1126/science.281.5373.78)
    • (1998) Science , vol.281 , pp. 78-81
    • Koltover, I.1    Salditt, T.2    Rädler, J.O.3    Safinya, C.R.4
  • 29
    • 0032805569 scopus 로고    scopus 로고
    • Phase diagram, stability and overcharging of lamellar cationic lipid-DNA self assembled complexes
    • Koltover, I., Salditt, T. & Safinya, C. R. 1999 Phase diagram, stability and overcharging of lamellar cationic lipid-DNA self assembled complexes. Biophys. J. 77, 915-924.
    • (1999) Biophys. J. , vol.77 , pp. 915-924
    • Koltover, I.1    Salditt, T.2    Safinya, C.R.3
  • 30
    • 0034687798 scopus 로고    scopus 로고
    • DNA condensation in two-dimensions
    • doi:10.1073/pnas.97.26.14046
    • Koltover, I., Wagner, K. & Safinya, C. R. 2000 DNA condensation in two-dimensions. Proc. Natl Acad. Sci. USA 97, 14046-14052. (doi:10.1073/pnas.97. 26.14046)
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 14046-14052
    • Koltover, I.1    Wagner, K.2    Safinya, C.R.3
  • 32
    • 84990422191 scopus 로고
    • Distribution of counterions around a cylindrical polyelectrolyte and Manning's condensation theory
    • doi:10.1002/bip.360230209
    • Le Bret, M. & Zimm, B. H. 1984 Distribution of counterions around a cylindrical polyelectrolyte and Manning's condensation theory. Biopolymers 23, 287-312. (doi:10.1002/bip.360230209)
    • (1984) Biopolymers , vol.23 , pp. 287-312
    • Le Bret, M.1    Zimm, B.H.2
  • 34
    • 0037622183 scopus 로고    scopus 로고
    • Three-dimensional imaging of lipid gene-carriers: Membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes
    • Lin, A. J., Slack, N. L., Ahmad, A., George, C. X., Samuel, C. E. & Safinya, C. R. 2003 Three-dimensional imaging of lipid gene-carriers: membrane charge density controls universal transfection behavior in lamellar cationic liposome-DNA complexes. Biophys. J. 84, 3307-3316.
    • (2003) Biophys. J. , vol.84 , pp. 3307-3316
    • Lin, A.J.1    Slack, N.L.2    Ahmad, A.3    George, C.X.4    Samuel, C.E.5    Safinya, C.R.6
  • 36
    • 11644276439 scopus 로고
    • Limiting laws and counterion condensation in polyelectrolyte solutions. I. Colligative properties
    • doi:10.1063/1.1672157
    • Manning, G. S. 1978 Limiting laws and counterion condensation in polyelectrolyte solutions. I. Colligative properties. J. Chem. Phys. 51, 924-933. (doi:10.1063/1.1672157)
    • (1978) J. Chem. Phys. , vol.51 , pp. 924-933
    • Manning, G.S.1
  • 37
    • 0034640230 scopus 로고    scopus 로고
    • Gene therapy on trial
    • doi:10.1126/science.288.5468.951
    • Marshall, E. 2002 Gene therapy on trial. Science 288, 951-952. (doi:10.1126/science.288.5468.951)
    • (2002) Science , vol.288 , pp. 951-952
    • Marshall, E.1
  • 38
    • 1642544672 scopus 로고    scopus 로고
    • Modeling of cationic lipid-DNA complexes
    • doi:10.2174/0929867043456142
    • May, S. & Ben-Shaul, A. 2004 Modeling of cationic lipid-DNA complexes. Curr. Med. Chem. 11, 151-167. (doi:10.2174/0929867043456142)
    • (2004) Curr. Med. Chem. , vol.11 , pp. 151-167
    • May, S.1    Ben-Shaul, A.2
  • 39
    • 0032479769 scopus 로고    scopus 로고
    • Cationic liposomes for gene therapy
    • doi:10.1002/(SICI)1521-3773(19980803)37:13/14〈1768:: AID-ANIE1768〉3.0.CO;2-4
    • Miller, A. D. 1998 Cationic liposomes for gene therapy. Angew. Chem. Int. Ed. 37, 1768-1785. (doi:10.1002/(SICI)1521-3773(19980803)37:13/14〈1768:: AID-ANIE1768〉3.0.CO;2-4)
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 1768-1785
    • Miller, A.D.1
  • 40
    • 0038482054 scopus 로고    scopus 로고
    • The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy
    • doi:10.2174/0929867033457485
    • Miller, A. D. 2003 The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy. Curr. Med. Chem. 10, 1195-1211. (doi:10.2174/0929867033457485)
    • (2003) Curr. Med. Chem. , vol.10 , pp. 1195-1211
    • Miller, A.D.1
  • 41
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • doi:10.1073/pnas.93.22.12349
    • Mislick, K. A. & Baldeschwieler, J. D. 1996 Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc. Natl Acad. Sci. USA 93, 12 349-12 354. (doi:10.1073/pnas.93.22.12349)
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 42
    • 0032475867 scopus 로고    scopus 로고
    • Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo
    • doi:10.1074/jbc.273.40.26164
    • Mounkes, L. C., Zhong, W., Ciprespalacin, G., Heath, T. D. & Debs, R. J. 1998 Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J. Biol. Chem. 273, 26 164-26 170. (doi:10.1074/jbc.273. 40.26164)
    • (1998) J. Biol. Chem. , vol.273 , pp. 26164-26170
    • Mounkes, L.C.1    Zhong, W.2    Ciprespalacin, G.3    Heath, T.D.4    Debs, R.J.5
  • 43
    • 0027517321 scopus 로고
    • Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
    • doi:10.1073/pnas.90.23.11307
    • Nabel, G. et al. 1993 Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc. Natl Acad. Sci. USA 90, 11 307-11 311. (doi:10.1073/pnas.90.23.11307)
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 11307-11311
    • Nabel, G.1
  • 44
    • 19744379853 scopus 로고    scopus 로고
    • Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: A probe of inter-protofilament bond strength
    • doi:10.1103/PhysRevLett.93.198104
    • Needleman, D. J., Ojeda-Lopez, M., Ewert, K., Jones, J., Miller, H. P., Wilson, L. & Safinya, C. R. 2004a Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of inter-protofilament bond strength. Phys. Rev. Lett. 93, 198104-1-198104-4. (doi:10.1103/PhysRevLett.93.198104)
    • (2004) Phys. Rev. Lett. , vol.93 , pp. 1981041-1981044
    • Needleman, D.J.1    Ojeda-Lopez, M.2    Ewert, K.3    Jones, J.4    Miller, H.P.5    Wilson, L.6    Safinya, C.R.7
  • 45
    • 9244244156 scopus 로고    scopus 로고
    • Higher order assembly of microtubules by counter-ions: From hexagonal bundles to living necklaces
    • doi:10.1073/pnas.0406076101
    • Needleman, D. J., Ojeda-Lopez, M., Raviv, U., Miller, H. P., Wilson, L. & Safinya, C. R. 2004b Higher order assembly of microtubules by counter-ions: from hexagonal bundles to living necklaces. Proc. Natl Acad. Sci. USA 101, 16099-16103. (doi:10.1073/pnas.0406076101)
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 16099-16103
    • Needleman, D.J.1    Ojeda-Lopez, M.2    Raviv, U.3    Miller, H.P.4    Wilson, L.5    Safinya, C.R.6
  • 46
    • 27744552013 scopus 로고    scopus 로고
    • Radial compression of microtubules by osmotic pressure and the mechanism of action of taxol and microtubule associated proteins
    • doi:10.1529/biophysj.104.057679
    • Needleman, D. J., Ojeda-Lopez, M., Raviv, U., Ewert, K., Jones, J., Miller, H. P., Wilson, L. & Safinya, C. R. 2005 Radial compression of microtubules by osmotic pressure and the mechanism of action of taxol and microtubule associated proteins. Biophys. J. 89, 3410-3423. (doi:10.1529/ biophysj.104.057679)
    • (2005) Biophys. J. , vol.89 , pp. 3410-3423
    • Needleman, D.J.1    Ojeda-Lopez, M.2    Raviv, U.3    Ewert, K.4    Jones, J.5    Miller, H.P.6    Wilson, L.7    Safinya, C.R.8
  • 47
    • 0036954247 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Nonviral vectors
    • doi:10.1038/sj.gt.3301923
    • Niidome, T. & Huang, L. 2002 Gene therapy progress and prospects: nonviral vectors. Gene Ther. 9, 1647-1652. (doi:10.1038/sj.gt.3301923)
    • (2002) Gene Ther. , vol.9 , pp. 1647-1652
    • Niidome, T.1    Huang, L.2
  • 48
    • 0031036238 scopus 로고    scopus 로고
    • Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
    • doi:10.1126/science.275.5301.810
    • Rädler, J. O., Koltover, I., Salditt, T. & Safinya, C. R. 1997 Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275, 810-814. (doi:10.1126/science.275.5301.810)
    • (1997) Science , vol.275 , pp. 810-814
    • Rädler, J.O.1    Koltover, I.2    Salditt, T.3    Safinya, C.R.4
  • 49
    • 0032117541 scopus 로고    scopus 로고
    • Structure and interfacial aspects of self- Assembled cationic lipid-DNA gene carrier complexes
    • doi:10.1021/la980360o
    • Rädler, J. O., Koltover, I., Salditt, T., Jamieson, A. & Safinya, C. R. 1998 Structure and interfacial aspects of self- assembled cationic lipid-DNA gene carrier complexes. Langmuir 14, 4272-4283. (doi:10.1021/la980360o)
    • (1998) Langmuir , vol.14 , pp. 4272-4283
    • Rädler, J.O.1    Koltover, I.2    Salditt, T.3    Jamieson, A.4    Safinya, C.R.5
  • 50
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • doi:10.1016/j.ymgme.2003.08.016
    • Raper, S. E., Chirmule, N., Lee, F. S., Wivel, N. A., Bagg, A., Gao, G. P., Wilson, J. M. & Batshaw, M. L. 2003 Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol. Genet. Metab. 80, 148-158. (doi:10.1016/j.ymgme.2003.08. 016)
    • (2003) Mol. Genet. Metab. , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6    Wilson, J.M.7    Batshaw, M.L.8
  • 51
    • 23844479241 scopus 로고    scopus 로고
    • Cationic liposome-microtubule complexes: Pathways to the formation of two state lipid-protein nanotubes with open or closed ends
    • doi:10.1073/pnas.0502183102
    • Raviv, U., Needleman, D. J., Li, Y., Miller, H. P., Wilson, L. & Safinya, C. R. 2005 Cationic liposome-microtubule complexes: pathways to the formation of two state lipid-protein nanotubes with open or closed ends. Proc. Natl Acad. Sci. USA 102, 11 167-11 172. (doi:10.1073/pnas.0502183102)
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 11167-11172
    • Raviv, U.1    Needleman, D.J.2    Li, Y.3    Miller, H.P.4    Wilson, L.5    Safinya, C.R.6
  • 52
    • 0030766190 scopus 로고    scopus 로고
    • Phase 1 trial of recombinant human interleukin-1-beta (rhIL-1-beta), carboplatin, and etoposide in patients with solid cancers: Southwest oncology group study 8940
    • Rinehart, J., Hersh, E., Issell, B., Triozzi, P., Buhles, W. & Neidhart, J. 1997 Phase 1 trial of recombinant human interleukin-1-beta (rhIL-1-beta), carboplatin, and etoposide in patients with solid cancers: southwest oncology group study 8940. Cancer Invest. 15, 403-410.
    • (1997) Cancer Invest. , vol.15 , pp. 403-410
    • Rinehart, J.1    Hersh, E.2    Issell, B.3    Triozzi, P.4    Buhles, W.5    Neidhart, J.6
  • 53
    • 0030981790 scopus 로고    scopus 로고
    • Molecular biology: Counterfeit chromosomes for humans
    • doi:10.1126/science.276.5309.38
    • Roush, W. 1997 Molecular biology: counterfeit chromosomes for humans. Science 278, 38-39. (doi:10.1126/science.276.5309.38)
    • (1997) Science , vol.278 , pp. 38-39
    • Roush, W.1
  • 54
    • 0035425499 scopus 로고    scopus 로고
    • Structures of lipid-DNA complexes: Supramolecular assembly and gene delivery
    • doi:10.1016/S0959-440X(00)00230-X
    • Safinya, C. R. 2001 Structures of lipid-DNA complexes: supramolecular assembly and gene delivery. Cure. Opin. Struct. Biol. 11, 440-448. (doi:10.1016/S0959-440X(00)00230-X)
    • (2001) Cure. Opin. Struct. Biol. , vol.11 , pp. 440-448
    • Safinya, C.R.1
  • 55
    • 33750519578 scopus 로고    scopus 로고
    • Non-viral vectors for gene therapy and drug delivery
    • Safinya, C. R. (Guest Ed.)
    • Safinya, C. R. (Guest Ed.) 2004 Non-viral vectors for gene therapy and drug delivery. Curr. Med. Chem. 11, 133-220.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 133-220
  • 56
    • 6144247394 scopus 로고
    • Universality in interacting membranes: The effect of cosurfactants on the interfacial rigidity
    • doi:10.1103/PhysRevLett.62.1134
    • Safinya, C. R., Sirota, E. B., Roux, D. & Smith, G. S. 1989 Universality in interacting membranes: the effect of cosurfactants on the interfacial rigidity. Phys. Rev. Lett. 62, 1134-1137. (doi:10.1103/PhysRevLett. 62.1134)
    • (1989) Phys. Rev. Lett. , vol.62 , pp. 1134-1137
    • Safinya, C.R.1    Sirota, E.B.2    Roux, D.3    Smith, G.S.4
  • 57
    • 0011088157 scopus 로고    scopus 로고
    • Cationic lipid-DNA complexes for gene delivery: Structure-function correlations
    • (ed. R. I. Mahato & S. W. Kim). London, UK: Taylor & Francis
    • Safinya, C. R., Slack, N., Lin, A. &: Koltover, I. 2002 Cationic lipid-DNA complexes for gene delivery: structure-function correlations. In Pharmaceutical perspectives of nucleic acid-based therapeutics (ed. R. I. Mahato & S. W. Kim), pp. 190-209. London, UK: Taylor & Francis.
    • (2002) Pharmaceutical Perspectives of Nucleic Acid-based Therapeutics , pp. 190-209
    • Safinya, C.R.1    Slack, N.2    Lin, A.3    Koltover, I.4
  • 58
    • 6144272654 scopus 로고    scopus 로고
    • Two dimensional smectic ordering of linear DNA chains in self-assembled DNA-cationic liposome mixtures
    • doi: 10.1103/PhysRevLett.79.2582
    • Salditt, T., Koltover, I., Rädler, O. & Safinya, C. R. 1997 Two dimensional smectic ordering of linear DNA chains in self-assembled DNA-cationic liposome mixtures. Phys. Rev. Lett. 79, 2582-2585. (doi: 10.1103/PhysRevLett. 79.2582)
    • (1997) Phys. Rev. Lett. , vol.79 , pp. 2582-2585
    • Salditt, T.1    Koltover, I.2    Rädler, O.3    Safinya, C.R.4
  • 59
    • 4243266876 scopus 로고    scopus 로고
    • Self-assembled DNA-cationic-lipid complexes: Two-dimensional smectic ordering, correlations, and interactions
    • doi:10.1103/PhysRevE.58.889
    • Salditt, T., Koltover, I., Rädler, O. & Safinya, C. R. 1998 Self-assembled DNA-cationic-lipid complexes: two-dimensional smectic ordering, correlations, and interactions. Phys. Rev. E 58, 889-904. (doi:10.1103/PhysRevE. 58.889)
    • (1998) Phys. Rev. E , vol.58 , pp. 889-904
    • Salditt, T.1    Koltover, I.2    Rädler, O.3    Safinya, C.R.4
  • 60
    • 0025134135 scopus 로고
    • II) phase, and non-lamellar phase transitions of lipids
    • II) phase, and non-lamellar phase transitions of lipids. Biochim. Biophys. Acta 1031, 1-69.
    • (1990) Biochim. Biophys. Acta , vol.1031 , pp. 1-69
    • Seddon, J.M.1
  • 61
    • 0032017880 scopus 로고    scopus 로고
    • Transfection of primary tumor cells and tumor cell lines with plasmid DNA/lipid complexes
    • Stopeck, A. T., Hersh, E. M., Brailey, J. L., Clark, P. R., Norman, J. & Parker, S. E. 1998 Transfection of primary tumor cells and tumor cell lines with plasmid DNA/lipid complexes. Cancer Gene Ther. 5, 119-126.
    • (1998) Cancer Gene Ther. , vol.5 , pp. 119-126
    • Stopeck, A.T.1    Hersh, E.M.2    Brailey, J.L.3    Clark, P.R.4    Norman, J.5    Parker, S.E.6
  • 62
    • 0034639426 scopus 로고    scopus 로고
    • Structure of complexes of cationic lipids and poly(glutamic acid) polypeptides: A pinched lamellar phase
    • doi:10.1021/ja991905j
    • Subramanian, G., Hjelm, R. P., Deming, T. J., Smith, G. S., Li, Y. & Safinya, C. R. 2000 Structure of complexes of cationic lipids and poly(glutamic acid) polypeptides: a pinched lamellar phase. J. Am. Chem. Soc. 122, 26-34. (doi:10.1021/ja991905j)
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 26-34
    • Subramanian, G.1    Hjelm, R.P.2    Deming, T.J.3    Smith, G.S.4    Li, Y.5    Safinya, C.R.6
  • 63
    • 0034680527 scopus 로고    scopus 로고
    • Genomics and gene therapy: Artificial chromosomes coming to life
    • doi:10.1126/science.290.5495.1308
    • Willard, H. F. 2000 Genomics and gene therapy: artificial chromosomes coming to life. Science 290, 1308-1309. (doi:10.1126/science.290.5495.1308)
    • (2000) Science , vol.290 , pp. 1308-1309
    • Willard, H.F.1
  • 64
    • 0242367234 scopus 로고    scopus 로고
    • Gene therapy - New challenges ahead
    • doi:10.1126/science,1091258
    • Williams, D. A. & Baum, C. 2003 Gene therapy - new challenges ahead. Science 302, 400-401. (doi:10.1126/science,1091258)
    • (2003) Science , vol.302 , pp. 400-401
    • Williams, D.A.1    Baum, C.2
  • 66
    • 0034674445 scopus 로고    scopus 로고
    • Hierarchical self-assembly of f-actin and cationic lipid complexes: Stacked three-layer tubule networks
    • doi:10.1126/science.288.5473.2035
    • Wong, G. C. L., Tang, J. X., Lin, A., Li, Y., Janmey, P. A. & Safinya, C. R. 2000 Hierarchical self-assembly of f-actin and cationic lipid complexes: stacked three-layer tubule networks. Science 288, 2035-2039. (doi:10.1126/science.288.5473.2035)
    • (2000) Science , vol.288 , pp. 2035-2039
    • Wong, G.C.L.1    Tang, J.X.2    Lin, A.3    Li, Y.4    Janmey, P.A.5    Safinya, C.R.6
  • 67
    • 0029019120 scopus 로고
    • Fusion of cationic liposomes with mammalian cells occurs after endocytosis
    • doi:10.1016/0005-2736(95)80017-A
    • Wrobel, I. & Collins, D. 1995 Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim. Biophys. Acta 1235, 296-304. (doi:10.1016/0005-2736(95)80017-A)
    • (1995) Biochim. Biophys. Acta , vol.1235 , pp. 296-304
    • Wrobel, I.1    Collins, D.2
  • 68
    • 33645454902 scopus 로고    scopus 로고
    • A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: Hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice
    • Ewert, K. K., Evans, H. M., Zidovska, A., Bouxsein, N. F., Ahmad, A. & Safinya, C. R. 2006 A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice. J. Am. Chem. Soc. 128, 3998-4006.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 3998-4006
    • Ewert, K.K.1    Evans, H.M.2    Zidovska, A.3    Bouxsein, N.F.4    Ahmad, A.5    Safinya, C.R.6


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