Liquid crystalline phases of dendritic lipid-DNA self-assemblies: Lamellar, hexagonal, and DNA bundles

Journal of Physical Chemistry B

Volumn 113, Issue 12, 2009, Pages 3694-3703

  Zidovska, Alexandra ^a   Evans, Heather M ^a   Ewert, Kai K ^a   Quispe, Joel ^b   Carragher, Bridget ^b   Potter, Clinton S ^b   Safinya, Cyrus R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DENDRIMERS; DNA; DRUG THERAPY; DYES; GENES; GENETIC ENGINEERING; HONEYCOMB STRUCTURES; LAMELLAR STRUCTURES; LIPOSOMES; MICELLES; OPTICAL MICROSCOPY; PHOSPHOLIPIDS; X RAY DIFFRACTION ANALYSIS;

BELL-SHAPED CURVES; CATIONIC LIPIDS; CATIONIC LIPOSOMES; CLINICAL TRIALS; CRYO-TEM; DNA COMPLEXES; DNA DELIVERIES; GENE THERAPIES; HEAD GROUPS; HEXAGONAL LATTICES; HEXAGONAL PHASE; HEXAGONAL PHASIS; HONEYCOMB LATTICES; KEY PARAMETERS; LAMELLAR PHASE; LIPID MICELLES; LIQUID-CRYSTALLINE PHASIS; MECHANISM OF ACTIONS; MEMBRANE CHARGES; MOLAR FRACTIONS; NON-VIRAL; SELF- ASSEMBLIES; THERAPEUTIC USE; TRANSFECTION EFFICIENCIES; VALENCIES; X-RAY DIFFRACTIONS; XRD;

NUCLEIC ACIDS;

EID: 65249157191     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp806863z     Document Type: Article

References (45)

1. Edelstein, M. L.; Abedi, M. R.; Wixon, J.; Edelstein, R. M. J. Gene Med. 2004, 6, 597.
2. Edelstein, M. L.; Abedi, M. R.; Wixon, J. J. Gene Med. 2007, 9, 833.
3. http://www.wiley.co.uk/genetherapy/clinical.
4. Ewert, K.; Slack, N. L.; Ahmad, A.; Evans, H. M.; Lin, A. J.; Samuel, C. E.; Safinya, C. R. Curr. Med. Chem. 2004, 11, 133.
5. Clark, P. R.; Hersh, E. M. Curr. Opin. Mol. Ther. 1999, 1, 158.
6. Chesnoy, S.; Huang, L. Annu. Rev. Biophys. Biomol. Struct. 2000, 29, 27.
7. Byk, G.; Dubertret, C.; Escriou, V.; Frederic, M.; Jaslin, G.; Rangara, R.; Pitard, B.; Crouzet, J.; Wils, P.; Schwartz, B.; Scherman, D. J. Med. Chem. 1998, 41, 224.
8. Huang, L., Hung, M.-C., Wagner, E. Non-Viral Vectors for Gene Therapy, 2nd ed.; Elsevier: San Diego, CA, 2005; Vol. 53.
9. Mahato, R. I., Kim, S. W., Eds. Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics; Taylor & Francis: London and New York, 2002.
10. Ewert, K. K.; Ahmad, A.; Evans, H. M.; Safinya, C. R. Expert Opin. Biol. Ther. 2005, 5, 33.
11. Boussif, O.; Lezoualch, F.; Zanta, M. A.; Mergny, M. D.; Scherman, D.; Demeneix, B.; Behr, J. P. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 7297.
12. Thomas, C. E.; Ehrhardt, A.; Kay, M. A. Nat. Rev. Genet. 2003, 4, 346.
13. Roth, C. M.; Sundaram, S. Annu. Rev. Biomed. Eng. 2004, 6, 397.
14. Byk, G.; Dubertret, C.; Escriou, V.; Frederic, M.; Jaslin, G.; Rangara, R.; Pitard, B.; Crouzet, J.; Wils, P.; Schartz, B.; Scherman, D. J. Med. Chem. 1998, 41, 224.
15. Behr, J. P. Bioconjugate Chem. 1994, 5, 382.
16. Miller, A. D. Angew. Chem., Int. Ed. Engl. 1998, 37, 1768.
17. Zabner, J. Adv. Drug Delivery Rev. 1997, 27, 17.
18. Ewert, K. K.; Evans, H. M.; Zidovska, A.; Bouxsein, N. F.; Ahmad, A.; Safinya, C. R. J. Am. Chem. Soc. 2006, 128, 3998.
19. Koltover, I.; Salditt, T.; Rädler, J. O.; Safinya, C. R. Science 1998, 281, 78.
20. Radler, J. O.; Koltover, I.; Salditt, T.; Safinya, C. R. Science 1997, 275, 810.
21. Tranchant, I.; Thompson, B.; Nicolazzi, C.; Mignet, N.; Scherman, D. J. Gene Med. 2004, 6, S24.
22. Ahmad, A.; Evans, H. M.; Ewert, K.; George, C. X.; Samuel, C. E.; Safinya, C. R. J. Gene Med. 2005, 7, 739.
23. Lin, A. J.; Slack, N. L.; Ahmad, A.; George, C. X.; Samuel, C. E.; Safinya, C. R. Biophys. J. 2003, 84, 3307.
24. Ewert, K.; Ahmad, A.; Evans, H. M.; Schmidt, H. W.; Safinya, C. R. J. Med. Chem. 2002, 45, 5023.
25. Bosman, A. W.; Janssen, H. M.; Meijer, E. W. Chem. Rev. 1999, 99, 1665.
26. Malik, N.; Wiwattanapatapee, R.; Klopsch, R.; Lorenz, K.; Frey, H.; Weener, J. W.; Meijer, E. W.; Paulus, W.; Duncan, R. J. Controlled Release 2000, 65, 133.
27. KukowskaLatallo, J. F.; Bielinska, A. U.; Johnson, J.; Spindler, R.; Tomalia, D. A.; Baker, J. R. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 4897.
28. Rudolph, C.; Lausier, J.; Naundorf, S.; Muller, R. H.; Rosenecker, J. J. Gene Med. 2000, 2, 269.
29. Bielinska, A. U.; Yen, A.; Wu, H. L.; Zahos, K. M.; Sun, R.; Weiner, N. D.; Baker, J. R.; Roessler, B. J. Biomaterials 2000, 21, 877.
30. Braun, C. S.; Fisher, M. T.; Tomalia, D. A.; Koe, G. S.; Koe, J. G.; Middaugh, C. R. Biophys. J. 2005, 88, 4146.
31. Evans, H. M.; Ahmad, A.; Ewert, K.; Pfohl, T.; Martin-Herranz, A.; Bruinsma, R. F.; Safinya, C. R. Phys. Rev. Lett. 2003, 91, 075501-1- 075501-4.
32. Ewert, K. K.; Evans, H. M.; Bouxsein, N. F.; Safinya, C. R. Bioconjugate Chem. 2006, 17, 877.
33. Quispe, J.; Damiano, J.; Mick, S. E.; Nackashi, D. P.; Fellmann, D.; Ajero, T. G.; Carragher, B.; Potter, C. S. Microsc. Microanal. 2007, 13, 365.
34. Suloway, C.; Pulokas, J.; Fellmann, D.; Cheng, A.; Guerra, F.; Quispe, J.; Stagg, S.; Potter, C. S.; Carragher, B. J. Struct. Biol. 2005, 151, 41.
35. Takahashi, T.; Harada, A.; Emi, N.; Kono, K. Bioconjugate Chem. 2005, 16, 1160.
36. Koltover, I.; Salditt, T.; Safinya, C. R. Biophys. J. 1999, 77, 915.
37. Boger, D. L.; Fink, B. E.; Brunette, S. R.; Tse, W. C.; Hedrick, M. P. J. Am. Chem. Soc. 2001, 123, 5878.
38. Tristram-Nagle, S.; Petrache, H. I.; Nagle, J. F. Biophys. J. 1998, 75, 917.
39. Podgornik, R.; Rau, D. C.; Parsegian, V. A. Macromolecules 1989, 22, 1780.
40. Farago, O.; Gronbech-Jensen, N. Biophys. J. 2007, 92, 3228.
41. Zidovska, A., Ewert, K. K., Quispe, J., Carragher, B., Potter, C. S., Safinya, C. R. Langmuir, in press.
42. Conwell, C. C.; Vilfan, I. D.; Hud, N. V. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9296.
43. Hud, N. V.; Downing, K. H. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 14925.
44. Zhou, S. Q.; Liang, D. H.; Burger, C.; Yeh, F. J.; Chu, B. Biomacromolecules 2004, 5, 1256.
45. Ghirlando, R.; Wachtel, E. J.; Arad, T.; Minsky, A. Biochemistry 1992, 31, 7110.