-
1
-
-
73949139582
-
Generational differences in the prevalence of hearing impairment in older adults
-
doi: 10.1093/aje/kwp370; pmid: 20008889
-
W. Zhan et al., Generational differences in the prevalence of hearing impairment in older adults. Am. J. Epidemiol. 171, 260-266 (2010). doi: 10.1093/aje/kwp370; pmid: 20008889
-
(2010)
Am. J. Epidemiol.
, vol.171
, pp. 260-266
-
-
Zhan, W.1
-
2
-
-
84882720760
-
Age-related cochlear synaptopathy: An early-onset contributor to auditory functional decline
-
doi: 10.1523/JNEUROSCI.1783-13.2013; pmid: 23966690
-
Y. Sergeyenko, K. Lall, M. C. Liberman, S. G. Kujawa, Age-related cochlear synaptopathy: An early-onset contributor to auditory functional decline. J. Neurosci. 33, 13686-13694 (2013). doi: 10.1523/JNEUROSCI.1783-13. 2013; pmid: 23966690
-
(2013)
J. Neurosci.
, vol.33
, pp. 13686-13694
-
-
Sergeyenko, Y.1
Lall, K.2
Liberman, M.C.3
Kujawa, S.G.4
-
3
-
-
0029029622
-
Fundamental immune mechanisms of the brain and inner ear. Otolaryngol
-
doi: 10.1016/S0194-5998(95)70170-2; pmid: 7777346
-
J. P. Harris, A. F. Ryan, Fundamental immune mechanisms of the brain and inner ear. Otolaryngol. Head Neck Surg. 112, 639-653 (1995). doi: 10.1016/S0194-5998(95)70170-2; pmid: 7777346
-
(1995)
Head Neck Surg.
, vol.112
, pp. 639-653
-
-
Harris, J.P.1
Ryan, A.F.2
-
4
-
-
84860538606
-
Drug delivery to the inner ear: Strategies and their therapeutic implications for sensorineural hearing loss
-
doi: 10.2174/156720112800389098; pmid: 22283653
-
T. Rivera, L. Sanz, G. Camarero, I. Varela-Nieto, Drug delivery to the inner ear: strategies and their therapeutic implications for sensorineural hearing loss. Curr. Drug Deliv. 9, 231 -242 (2012). doi: 10.2174/ 156720112800389098; pmid: 22283653
-
(2012)
Curr. Drug Deliv.
, vol.9
, pp. 231-242
-
-
Rivera, T.1
Sanz, L.2
Camarero, G.3
Varela-Nieto, I.4
-
5
-
-
0036106166
-
K+ cycling and the endocochlear potential
-
doi: 10.1016/S0378-5955(02)00279-4; pmid: 12031509
-
P. Wangemann, K+ cycling and the endocochlear potential. Hear. Res. 165, 1-9 (2002). doi: 10.1016/S0378-5955(02)00279-4; pmid: 12031509
-
(2002)
Hear. Res.
, vol.165
, pp. 1-9
-
-
Wangemann, P.1
-
6
-
-
84897570588
-
Conditioning the cochlea to facilitate survival and integration of exogenous cells into the auditory epithelium
-
Y. H. Park et al., Conditioning the cochlea to facilitate survival and integration of exogenous cells into the auditory epithelium. Mol. Ther. 22, 873-880 (2014).
-
(2014)
Mol. Ther.
, vol.22
, pp. 873-880
-
-
Park, Y.H.1
-
7
-
-
84867896931
-
The cochlear implant: Historical aspects and future prospects
-
Hoboken doi: 10.1002/ar.22580; pmid: 23044644
-
A. A. Eshraghi et al., The cochlear implant: Historical aspects and future prospects. Anat. Rec. (Hoboken) 295, 1967- 1980 (2012). doi: 10.1002/ar.22580; pmid: 23044644
-
(2012)
Anat. Rec.
, vol.295
, pp. 1967-1980
-
-
Eshraghi, A.A.1
-
9
-
-
80055102883
-
Cochlear infrastructure for electrical hearing
-
doi: 10.1016/j.heares.2011.05.002; pmid: 21605648
-
B. E. Pfingst et al., Cochlear infrastructure for electrical hearing. Hear. Res. 281, 65-73 (2011). doi: 10.1016/j.heares.2011.05.002; pmid: 21605648
-
(2011)
Hear. Res.
, vol.281
, pp. 65-73
-
-
Pfingst, B.E.1
-
10
-
-
79960688516
-
Towards gene therapy for deafness
-
doi: 10.1002/jcp.22617; pmid: 21792906
-
M. Di Domenico et al., Towards gene therapy for deafness. J. Cell. Physiol. 226, 2494 -2499 (2011). doi: 10.1002/jcp.22617; pmid: 21792906
-
(2011)
J. Cell. Physiol.
, vol.226
, pp. 2494-2499
-
-
Di Domenico, M.1
-
11
-
-
84875379496
-
Gene therapy for the inner ear
-
doi: 10.1016/j.heares.2012.11.017; pmid: 23265411
-
H. Fukui, Y. Raphael, Gene therapy for the inner ear. Hear. Res. 297, 99-105 (2013). doi: 10.1016/j.heares.2012.11.017; pmid: 23265411
-
(2013)
Hear. Res.
, vol.297
, pp. 99-105
-
-
Fukui, H.1
Raphael, Y.2
-
12
-
-
84874783720
-
Gene transfer in inner ear cells: A challenging race
-
doi: 10.1038/gt.2012.51; pmid: 22739386
-
R. Sacheli, L. Delacroix, P. Vandenackerveken, L. Nguyen, B. Malgrange, Gene transfer in inner ear cells: A challenging race. Gene Ther. 20, 237-247 (2013). doi: 10.1038/gt.2012.51; pmid: 22739386
-
(2013)
Gene Ther.
, vol.20
, pp. 237-247
-
-
Sacheli, R.1
Delacroix, L.2
Vandenackerveken, P.3
Nguyen, L.4
Malgrange, B.5
-
13
-
-
33947370533
-
Lentiviral gene replacement therapy of retinas in a mouse model for Usher syndrome type 1B
-
doi: 10.1038/sj.gt.3302897; pmid: 17268537
-
T. Hashimoto et al., Lentiviral gene replacement therapy of retinas in a mouse model for Usher syndrome type 1B. Gene Ther. 14, 584-594 (2007). doi: 10.1038/sj.gt.3302897; pmid: 17268537
-
(2007)
Gene Ther.
, vol.14
, pp. 584-594
-
-
Hashimoto, T.1
-
14
-
-
80051850929
-
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice
-
doi: 10.1371/journal.pone.0023279; pmid: 21876744
-
G. Crispino et al., BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice. PLOS ONE 6, e23279 (2011). doi: 10.1371/journal.pone.0023279; pmid: 21876744
-
(2011)
PLOS ONE
, vol.6
-
-
Crispino, G.1
-
15
-
-
84891740321
-
Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice
-
pmid: 24225640
-
Q. Yu et al., Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice. Gene Ther. 21, 71-80 (2013). pmid: 24225640
-
(2013)
Gene Ther.
, vol.21
, pp. 71-80
-
-
Yu, Q.1
-
16
-
-
0034609284
-
Relation between choice of partner and high frequency of connexin-26 deafness
-
doi: 10.1016/S0140-6736(00)02565-4; pmid: 10981905
-
W. E. Nance, X. Z. Liu, A. Pandya, Relation between choice of partner and high frequency of connexin-26 deafness. Lancet 356, 500-501 (2000). doi: 10.1016/S0140-6736(00)02565-4; pmid: 10981905
-
(2000)
Lancet
, vol.356
, pp. 500-501
-
-
Nance, W.E.1
Liu, X.Z.2
Pandya, A.3
-
17
-
-
79959972940
-
Viral vector tropism for supporting cells in the developing murine cochlea
-
doi: 10.1016/j.heares.2011.03.016; pmid: 21530627
-
A. M. Sheffield et al., Viral vector tropism for supporting cells in the developing murine cochlea. Hear. Res. 277, 28-36 (2011). doi: 10.1016/j.heares.2011.03.016; pmid: 21530627
-
(2011)
Hear. Res.
, vol.277
, pp. 28-36
-
-
Sheffield, A.M.1
-
18
-
-
84865087884
-
Inner ear gene transfection in neonatal mice using adeno-associated viral vector: A comparison of two approaches
-
doi: 10.1371/journal.pone.0043218; pmid: 22912830
-
L. Xia, S. Yin, J. Wang, Inner ear gene transfection in neonatal mice using adeno-associated viral vector: A comparison of two approaches. PLOS ONE 7, e43218 (2012). doi: 10.1371/journal.pone.0043218; pmid: 22912830
-
(2012)
PLOS ONE
, vol.7
-
-
Xia, L.1
Yin, S.2
Wang, J.3
-
19
-
-
79958287787
-
Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear
-
doi: 10.1038/gt.2010.175; pmid: 21209625
-
L. A. Kilpatrick et al., Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear. Gene Ther. 18, 569-578 (2011). doi: 10.1038/gt.2010.175; pmid: 21209625
-
(2011)
Gene Ther.
, vol.18
, pp. 569-578
-
-
Kilpatrick, L.A.1
-
20
-
-
84055217017
-
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes
-
doi: 10.1172/JCI60405; pmid: 22105175
-
Y. Kawashima et al., Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J. Clin. Invest. 121, 4796-4809 (2011). doi: 10.1172/JCI60405; pmid: 22105175
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4796-4809
-
-
Kawashima, Y.1
-
21
-
-
84906937946
-
TMC function in hair cell transduction
-
doi: 10.1016/j.heares.2014.01.001; pmid: 24423408
-
J. R. Holt, B. Pan, M. A. Koussa, Y. Asai, TMC function in hair cell transduction. Hear. Res. (2014). doi: 10.1016/j.heares.2014.01.001; pmid: 24423408
-
(2014)
Hear. Res.
-
-
Holt, J.R.1
Pan, B.2
Koussa, M.A.3
Asai, Y.4
-
22
-
-
0036510053
-
Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function
-
doi: 10.1038/ng842; pmid: 11850618
-
K. Kurima et al., Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function. Nat. Genet. 30, 277-284 (2002). doi: 10.1038/ng842; pmid: 11850618
-
(2002)
Nat. Genet.
, vol.30
, pp. 277-284
-
-
Kurima, K.1
-
23
-
-
84864297772
-
Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy
-
doi: 10.1016/j.neuron.2012.05.019; pmid: 22841313
-
O. Akil et al., Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy. Neuron 75, 283-293 (2012). doi: 10.1016/j.neuron.2012.05.019; pmid: 22841313
-
(2012)
Neuron
, vol.75
, pp. 283-293
-
-
Akil, O.1
-
24
-
-
84866887475
-
Gene therapy for deaf mice goes viral
-
doi: 10.1038/mt.2012.196; pmid: 23023054
-
J. R. Holt, L. H. Vandenberghe, Gene therapy for deaf mice goes viral. Mol. Ther. 20, 1836-1837 (2012). doi: 10.1038/mt.2012.196; pmid: 23023054
-
(2012)
Mol. Ther.
, vol.20
, pp. 1836-1837
-
-
Holt, J.R.1
Vandenberghe, L.H.2
-
25
-
-
84864320271
-
Have you heard? Viral-mediated gene therapy restores hearing
-
doi: 10.1016/j.neuron.2012.06.008; pmid: 22841304
-
D. M. Martin, Y. Raphael, Have you heard? Viral-mediated gene therapy restores hearing. Neuron 75, 188-190 (2012). doi: 10.1016/j.neuron.2012.06.008; pmid: 22841304
-
(2012)
Neuron
, vol.75
, pp. 188-190
-
-
Martin, D.M.1
Raphael, Y.2
-
26
-
-
0032947634
-
A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness
-
doi: 10.1038/7693; pmid: 10192385
-
S. Yasunaga et al., A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness. Nat. Genet. 21, 363-369 (1999). doi: 10.1038/7693; pmid: 10192385
-
(1999)
Nat. Genet.
, vol.21
, pp. 363-369
-
-
Yasunaga, S.1
-
27
-
-
33749994043
-
Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse
-
doi: 10.1016/j.cell.2006.08.040; pmid: 17055430
-
I. Roux et al., Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127, 277-289 (2006). doi: 10.1016/j.cell.2006.08.040; pmid: 17055430
-
(2006)
Cell
, vol.127
, pp. 277-289
-
-
Roux, I.1
-
28
-
-
79955777937
-
Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis
-
doi: 10.1523/JNEUROSCI.5122-10.2011; pmid: 21451027
-
E. Reisinger et al., Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. J. Neurosci. 31, 4886-4895 (2011). doi: 10.1523/JNEUROSCI.5122-10.2011; pmid: 21451027
-
(2011)
J. Neurosci.
, vol.31
, pp. 4886-4895
-
-
Reisinger, E.1
-
29
-
-
84875380031
-
A brief history of hair cell regeneration research and speculations on the future
-
doi: 10.1016/j.heares.2012.12.014; pmid: 23321648
-
E. W. Rubel, S. A. Furrer, J. S. Stone, A brief history of hair cell regeneration research and speculations on the future. Hear. Res. 297, 42-51 (2013). doi: 10.1016/j.heares.2012.12.014; pmid: 23321648
-
(2013)
Hear. Res.
, vol.297
, pp. 42-51
-
-
Rubel, E.W.1
Furrer, S.A.2
Stone, J.S.3
-
30
-
-
0033546004
-
Math1: An essential gene for the generation of inner ear hair cells
-
doi: 10.1126/science.284.5421.1837; pmid: 10364557
-
N. A. Bermingham et al., Math1: an essential gene for the generation of inner ear hair cells. Science 284, 1837-1841 (1999).doi: 10.1126/science.284. 5421.1837; pmid: 10364557
-
(1999)
Science
, vol.284
, pp. 1837-1841
-
-
Bermingham, N.A.1
-
31
-
-
16244411316
-
Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals
-
doi: 10.1038/nm1193; pmid: 15711559
-
M. Izumikawa et al., Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat. Med. 11, 271 -276 (2005). doi: 10.1038/nm1193; pmid: 15711559
-
(2005)
Nat. Med.
, vol.11
, pp. 271-276
-
-
Izumikawa, M.1
-
32
-
-
52949112282
-
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
-
doi: 10.1038/nature07265; pmid: 18754012
-
S. P. Gubbels, D. W. Woessner, J. C. Mitchell, A. J. Ricci, J. V. Brigande, Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 455, 537-541 (2008). doi: 10.1038/nature07265; pmid: 18754012
-
(2008)
Nature
, vol.455
, pp. 537-541
-
-
Gubbels, S.P.1
Woessner, D.W.2
Mitchell, J.C.3
Ricci, A.J.4
Brigande, J.V.5
-
33
-
-
84866916331
-
Regeneration of stereocilia of hair cells by forced Atoh1 expression in the adult mammalian cochlea
-
doi: 10.1371/journal.pone.0046355; pmid: 23029493
-
S. M. Yang et al ., Regeneration of stereocilia of hair cells by forced Atoh1 expression in the adult mammalian cochlea. PLOS ONE 7, e46355 (2012). doi: 10.1371/journal.pone.0046355; pmid: 23029493
-
(2012)
PLOS ONE
, vol.7
-
-
Yang, S.M.1
-
34
-
-
70449643246
-
Adding insult to injury: Cochlear nerve degeneration after "temporary" noise-induced hearing loss
-
doi: 10.1523/JNEUROSCI.2845-09.2009; pmid: 19906956
-
S. G. Kujawa, M. C. Liberman, Adding insult to injury: Cochlear nerve degeneration after "temporary" noise-induced hearing loss. J. Neurosci. 29, 14077-14085 (2009). doi: 10.1523/JNEUROSCI.2845-09.2009; pmid: 19906956
-
(2009)
J. Neurosci.
, vol.29
, pp. 14077-14085
-
-
Kujawa, S.G.1
Liberman, M.C.2
-
35
-
-
0029014667
-
Complementary roles of BDNF and NT-3 in vestibular and auditory development
-
doi: 10.1016/0896-6273(95)90263-5; pmid: 7605630
-
P. Ernfors, T. Van De Water, J. Loring, R. Jaenisch, Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14, 1153-1164 (1995). doi: 10.1016/0896-6273(95)90263-5; pmid: 7605630
-
(1995)
Neuron
, vol.14
, pp. 1153-1164
-
-
Ernfors, P.1
Van De Water, T.2
Loring, J.3
Jaenisch, R.4
-
36
-
-
0030731181
-
Expression of neurotrophins and Trk receptors in the developing, adult, and regenerating avian cochlea
-
doi: 10.1002/(SICI)1097-4695(199712)33:7〈1019::AID
-
U. Pirvola et al., Expression of neurotrophins and Trk receptors in the developing, adult, and regenerating avian cochlea. J. Neurobiol. 33, 1019 -1033 (1997). doi: 10.1002/(SICI)1097-4695(199712)33:7〈1019::AIDNEU11〉3.0. CO;2-A; pmid: 9407020
-
(1997)
J. Neurobiol.
, vol.33
, pp. 1019-1033
-
-
Pirvola, U.1
-
37
-
-
33846542432
-
Dynamic patterns of neurotrophin 3 expression in the postnatal mouse inner ear
-
doi: 10.1002/cne.21227; pmid: 17206617
-
M. Sugawara, J. C. Murtie, K. M. Stankovic, M. C. Liberman, G. Corfas, Dynamic patterns of neurotrophin 3 expression in the postnatal mouse inner ear. J. Comp. Neurol. 501, 30-37 (2007). doi: 10.1002/cne.21227; pmid: 17206617
-
(2007)
J. Comp. Neurol.
, vol.501
, pp. 30-37
-
-
Sugawara, M.1
Murtie, J.C.2
Stankovic, K.M.3
Liberman, M.C.4
Corfas, G.5
-
38
-
-
84855680854
-
Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea
-
doi: 10.1523/JNEUROSCI.4678-11.2012; pmid: 22238076
-
Y. Zilberstein, M. C. Liberman, G. Corfas, Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea. J. Neurosci. 32, 405-410 (2012). doi: 10.1523/JNEUROSCI.4678-11.2012; pmid: 22238076
-
(2012)
J. Neurosci.
, vol.32
, pp. 405-410
-
-
Zilberstein, Y.1
Liberman, M.C.2
Corfas, G.3
-
39
-
-
0030046365
-
Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: Model for treatment of neuron loss following cochlear degeneration
-
doi: 10.1089/hum.1996.7.2-173; pmid: 8788168
-
M. D. Geschwind et al., Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: model for treatment of neuron loss following cochlear degeneration. Hum. Gene Ther. 7, 173-182 (1996). doi: 10.1089/hum.1996.7.2-173; pmid: 8788168
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 173-182
-
-
Geschwind, M.D.1
-
40
-
-
77953138652
-
Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea
-
doi: 10.1038/mt.2010.28; pmid: 20216530
-
A. K. Wise et al., Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea. Mol. Ther. 18, 1111-1122 (2010). doi: 10.1038/mt.2010.28; pmid: 20216530
-
(2010)
Mol. Ther.
, vol.18
, pp. 1111-1122
-
-
Wise, A.K.1
-
41
-
-
84871289089
-
Neurotrophin gene therapy for sustained neural preservation after deafness
-
doi: 10.1371/journal.pone.0052338; pmid: 23284995
-
P. J. Atkinson et al., Neurotrophin gene therapy for sustained neural preservation after deafness. PLOS ONE 7, e52338 (2012). doi: 10.1371/journal.pone.0052338; pmid: 23284995
-
(2012)
PLOS ONE
, vol.7
-
-
Atkinson, P.J.1
-
42
-
-
84899507779
-
Close-field electroporation gene delivery using the cochlear implant electrode array enhances the bionic ear
-
Jeremy L. Pinyon et al., Close-field electroporation gene delivery using the cochlear implant electrode array enhances the bionic ear. Sci. Transl. Med. 6, 233ra54 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Jeremy, L.P.E.A.1
-
43
-
-
66149168687
-
Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells
-
doi: 10.1002/stem.62; pmid: 19418454
-
W. Chen et al., Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells. Stem Cells 27, 1196-1204 (2009). doi: 10.1002/stem.62; pmid: 19418454
-
(2009)
Stem Cells
, vol.27
, pp. 1196-1204
-
-
Chen, W.1
-
44
-
-
0344633590
-
Generation of hair cells by stepwise differentiation of embryonic stem cells
-
doi: 10.1073/pnas.2334503100; pmid: 14593207
-
H. Li, G. Roblin, H. Liu, S. Heller, Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 100, 13495-13500 (2003). doi: 10.1073/pnas.2334503100; pmid: 14593207
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 13495-13500
-
-
Li, H.1
Roblin, G.2
Liu, H.3
Heller, S.4
-
45
-
-
77952493569
-
Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells
-
doi: 10.1016/j.cell.2010.03.035; pmid: 20478259
-
K. Oshima et al., Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell 141, 704-716 (2010). doi: 10.1016/j.cell.2010.03.035; pmid: 20478259
-
(2010)
Cell
, vol.141
, pp. 704-716
-
-
Oshima, K.1
-
46
-
-
10944252852
-
Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear
-
doi: 10.1523/JNEUROSCI.2662-04.2004; pmid: 15590931
-
G. S. Géléoc, J. R. Risner, J. R. Holt, Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear. J. Neurosci. 24, 11148-11159 (2004). doi: 10.1523/JNEUROSCI.2662-04.2004; pmid: 15590931
-
(2004)
J. Neurosci.
, vol.24
, pp. 11148-11159
-
-
Géléoc, G.S.1
Risner, J.R.2
Holt, J.R.3
-
47
-
-
84881474378
-
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
-
doi: 10.1038/nature12298; pmid: 23842490
-
K. R. Koehler, A. M. Mikosz, A. I. Molosh, D. Patel, E. Hashino, Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature 500, 217-221 (2013). doi: 10.1038/nature12298; pmid: 23842490
-
(2013)
Nature
, vol.500
, pp. 217-221
-
-
Koehler, K.R.1
Mikosz, A.M.2
Molosh, A.I.3
Patel, D.4
Hashino, E.5
-
48
-
-
84855661191
-
Age-related primary cochlear neuronal degeneration in human temporal bones
-
doi: 10.1007/s10162-011-0283-2; pmid: 21748533
-
C. A. Makary, J. Shin, S. G. Kujawa, M. C. Liberman, S. N. Merchant, Age-related primary cochlear neuronal degeneration in human temporal bones. J. Assoc. Res. Otolaryngol. 12, 711-717 (2011). doi: 10.1007/s10162-011-0283-2; pmid: 21748533
-
(2011)
J. Assoc. Res. Otolaryngol.
, vol.12
, pp. 711-717
-
-
Makary, C.A.1
Shin, J.2
Kujawa, S.G.3
Liberman, M.C.4
Merchant, S.N.5
-
49
-
-
84863660179
-
Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea
-
doi: 10.1523/JNEUROSCI.1064-12.2012; pmid: 22787049
-
F. Shi, J. S. Kempfle, A. S. Edge, Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea. J. Neurosci. 32, 9639-9648 (2012). doi: 10.1523/JNEUROSCI.1064-12.2012; pmid: 22787049
-
(2012)
J. Neurosci.
, vol.32
, pp. 9639-9648
-
-
Shi, F.1
Kempfle, J.S.2
Edge, A.S.3
-
50
-
-
58549103703
-
Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage
-
doi: 10.1073/pnas.0808044105; pmid: 19064919
-
D. Wei et al., Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage. Proc. Natl. Acad. Sci. U.S.A. 105, 21000-21005 (2008). doi: 10.1073/pnas. 0808044105; pmid: 19064919
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 21000-21005
-
-
Wei, D.1
-
51
-
-
36249013594
-
BMP4 induction of sensory neurons from human embryonic stem cells and reinnervation of sensory epithelium
-
doi: 10.1111/j.1460-9568.2007.05909.x; pmid: 18005071
-
F. Shi, C. E. Corrales, M. C. Liberman, A. S. Edge, BMP4 induction of sensory neurons from human embryonic stem cells and reinnervation of sensory epithelium. Eur. J. Neurosci. 26, 3016-3023 (2007). doi: 10.1111/j.1460-9568. 2007.05909.x; pmid: 18005071
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 3016-3023
-
-
Shi, F.1
Corrales, C.E.2
Liberman, M.C.3
Edge, A.S.4
-
52
-
-
84867337075
-
Restoration of auditory evoked responses by human ES-cell-derived otic progenitors
-
doi: 10.1038/nature11415; pmid: 22972191
-
W. Chen et al., Restoration of auditory evoked responses by human ES-cell-derived otic progenitors. Nature 490, 278-282 (2012). doi: 10.1038/nature11415; pmid: 22972191
-
(2012)
Nature
, vol.490
, pp. 278-282
-
-
Chen, W.1
-
53
-
-
44449116119
-
Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells
-
doi: 10.1073/pnas.0708704105; pmid: 18391221
-
T. Kondo et al., Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 105, 5780- 5785 (2008). doi: 10.1073/pnas.0708704105; pmid: 18391221
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 5780-5785
-
-
Kondo, T.1
-
54
-
-
58149387077
-
Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: In vitro and in vivo studies
-
doi: 10.1523/JNEUROSCI.0563-08.2008; pmid: 19036956
-
J. H. Reyes et al., Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. J. Neurosci. 28, 12622-12631 (2008). doi: 10.1523/JNEUROSCI.0563-08.2008; pmid: 19036956
-
(2008)
J. Neurosci.
, vol.28
, pp. 12622-12631
-
-
Reyes, J.H.1
-
55
-
-
33750820223
-
Engraftment and differentiation of embryonic stem cell-derived neural progenitor cells in the cochlear nerve trunk: Growth of processes into the organ of Corti
-
doi: 10.1002/neu.20310; pmid: 17013931
-
C. E. Corrales et al ., Engraftment and differentiation of embryonic stem cell-derived neural progenitor cells in the cochlear nerve trunk: Growth of processes into the organ of Corti. J. Neurobiol. 66, 1489-1500 (2006). doi: 10.1002/neu.20310; pmid: 17013931
-
(2006)
J. Neurobiol.
, vol.66
, pp. 1489-1500
-
-
Corrales, C.E.1
-
56
-
-
84875374779
-
Prospects for replacement of auditory neurons by stem cells
-
doi: 10.1016/j.heares.2013.01.017; pmid: 23370457
-
F. Shi, A. S. Edge, Prospects for replacement of auditory neurons by stem cells. Hear. Res. 297, 106-112 (2013). doi: 10.1016/j.heares.2013.01.017; pmid: 23370457
-
(2013)
Hear. Res.
, vol.297
, pp. 106-112
-
-
Shi, F.1
Edge, A.S.2
-
57
-
-
33745577647
-
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
-
doi: 10.1038/nature04849; pmid: 16791196
-
P. M. White, A. Doetzlhofer, Y. S. Lee, A. K. Groves, N. Segil, Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature 441, 984-987 (2006). doi: 10.1038/nature04849; pmid: 16791196
-
(2006)
Nature
, vol.441
, pp. 984-987
-
-
White, P.M.1
Doetzlhofer, A.2
Lee, Y.S.3
Groves, A.K.4
Segil, N.5
-
58
-
-
84861448404
-
Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea
-
doi: 10.1073/pnas.1202774109; pmid: 22562792
-
R. Chai et al., Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proc. Natl. Acad. Sci. U.S.A. 109, 8167- 8172 (2012). doi: 10.1073/pnas.1202774109; pmid: 22562792
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 8167-8172
-
-
Chai, R.1
-
59
-
-
80054790130
-
Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea
-
doi: 10.1007/s10162-011-0267-2; pmid: 21472479
-
R. Chai et al., Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea. J. Assoc. Res. Otolaryngol. 12, 455-469 (2011). doi: 10.1007/s10162-011-0267-2; pmid: 21472479
-
(2011)
J. Assoc. Res. Otolaryngol.
, vol.12
, pp. 455-469
-
-
Chai, R.1
-
60
-
-
84882736739
-
Generation of hair cells in neonatal mice by b-catenin overexpression in Lgr5-positive cochlear progenitors
-
doi: 10.1073/pnas.1219952110; pmid: 23918377
-
F. Shi, L. Hu, A. S. Edge, Generation of hair cells in neonatal mice by b-catenin overexpression in Lgr5-positive cochlear progenitors. Proc. Natl. Acad. Sci. U.S.A. 110, 13851-13856 (2013). doi: 10.1073/pnas.1219952110; pmid: 23918377
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 13851-13856
-
-
Shi, F.1
Hu, L.2
Edge, A.S.3
-
61
-
-
84896102205
-
Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea
-
doi: 10.1016/j.stemcr.2014.01.008; pmid: 24672754
-
N. F. Bramhall, F. Shi, K. Arnold, K. Hochedlinger, A. S. Edge, Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea. Stem Cell Rev. 2, 311-322 (2014). doi: 10.1016/j.stemcr.2014.01.008; pmid: 24672754
-
(2014)
Stem Cell Rev.
, vol.2
, pp. 311-322
-
-
Bramhall, N.F.1
Shi, F.2
Arnold, K.3
Hochedlinger, K.4
Edge, A.S.5
-
62
-
-
84893220555
-
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo
-
doi: 10.1242/dev.103036; pmid: 24496619
-
B. C. Cox et al., Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo. Development 141, 816-829 (2014). doi: 10.1242/dev.103036; pmid: 24496619
-
(2014)
Development
, vol.141
, pp. 816-829
-
-
Cox, B.C.1
-
63
-
-
79958249971
-
Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells
-
doi: 10.1523/JNEUROSCI.6366-10.2011; pmid: 21653840
-
S. J. Jeon, M. Fujioka, S. C. Kim, A. S. Edge, Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells. J. Neurosci. 31, 8351-8358 (2011). doi: 10.1523/JNEUROSCI.6366-10.2011; pmid: 21653840
-
(2011)
J. Neurosci.
, vol.31
, pp. 8351-8358
-
-
Jeon, S.J.1
Fujioka, M.2
Kim, S.C.3
Edge, A.S.4
-
64
-
-
84883318455
-
Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea
-
doi: 10.1371/journal.pone.0073276; pmid: 24023676
-
S. Korrapati, I. Roux, E. Glowatzki, A. Doetzlhofer, Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. PLOS ONE 8, e73276 (2013). doi: 10.1371/journal.pone.0073276; pmid: 24023676
-
(2013)
PLOS ONE
, vol.8
-
-
Korrapati, S.1
Roux, I.2
Glowatzki, E.3
Doetzlhofer, A.4
-
65
-
-
84872173335
-
Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma
-
doi: 10.1016/j.neuron.2012.10.032; pmid: 23312516
-
K. Mizutari et al., Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron 77, 58- 69 (2013). doi: 10.1016/j.neuron.2012.10.032; pmid: 23312516
-
(2013)
Neuron
, vol.77
, pp. 58-69
-
-
Mizutari, K.1
-
66
-
-
13844309351
-
Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein
-
doi: 10.1126/science.1106642; pmid: 15653467
-
C. Sage et al., Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science 307, 1114-1118 (2005).doi: 10.1126/science.1106642; pmid: 15653467
-
(2005)
Science
, vol.307
, pp. 1114-1118
-
-
Sage, C.1
-
67
-
-
33846982227
-
p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis
-
doi: 10.1523/JNEUROSCI.4956-06.2007; pmid: 17287518
-
H. Laine et al., p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. J. Neurosci. 27, 1434-1444 (2007). doi: 10.1523/JNEUROSCI.4956-06.2007; pmid: 17287518
-
(2007)
J. Neurosci.
, vol.27
, pp. 1434-1444
-
-
Laine, H.1
-
68
-
-
84875212043
-
Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness
-
doi: 10.1038/nm.3106; pmid: 23380860
-
J. J. Lentz et al., Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness. Nat. Med. 19, 345-350 (2013). doi: 10.1038/nm.3106; pmid: 23380860
-
(2013)
Nat. Med.
, vol.19
, pp. 345-350
-
-
Lentz, J.J.1
-
69
-
-
0033816925
-
A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C
-
doi: 10.1038/79171; pmid: 10973247
-
E. Verpy et al., A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C. Nat. Genet. 26, 51-55 (2000). doi: 10.1038/79171; pmid: 10973247
-
(2000)
Nat. Genet.
, vol.26
, pp. 51-55
-
-
Verpy, E.1
-
70
-
-
0033822063
-
A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene
-
doi: 10.1038/79178; pmid: 10973248
-
M. Bitner-Glindzicz et al., A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene. Nat. Genet. 26, 56-60 (2000). doi: 10.1038/79178; pmid: 10973248
-
(2000)
Nat. Genet.
, vol.26
, pp. 56-60
-
-
Bitner-Glindzicz, M.1
-
71
-
-
73949146587
-
Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells
-
doi: 10.1007/s00424-009-0711-x; pmid: 19756723
-
N. Michalski et al., Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells. Pflugers Arch. 459, 115-130 (2009). doi: 10.1007/s00424-009-0711-x; pmid: 19756723
-
(2009)
Pflugers Arch.
, vol.459
, pp. 115-130
-
-
Michalski, N.1
-
72
-
-
77649114893
-
Deafness and retinal degeneration in a novel USH1C knock-in mouse model
-
doi: 10.1002/dneu.20771; pmid: 20095043
-
J. J. Lentz et al., Deafness and retinal degeneration in a novel USH1C knock-in mouse model. Dev. Neurobiol. 70, 253-267 (2010). doi: 10.1002/dneu.20771; pmid: 20095043
-
(2010)
Dev. Neurobiol.
, vol.70
, pp. 253-267
-
-
Lentz, J.J.1
-
73
-
-
67651209091
-
Therapeutic regulation of gene expression in the inner ear using RNA interference
-
doi: 10.1159/000218205; pmid: 19494570
-
Y. Maeda, A. M. Sheffield, R. J. Smith, Therapeutic regulation of gene expression in the inner ear using RNA interference. Adv. Otorhinolaryngol. 66, 13-36 (2009). doi: 10.1159/000218205; pmid: 19494570
-
(2009)
Adv. Otorhinolaryngol.
, vol.66
, pp. 13-36
-
-
Maeda, Y.1
Sheffield, A.M.2
Smith, R.J.3
-
74
-
-
84879264708
-
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
-
doi: 10.1016/j.tibtech.2013.04.004; pmid: 23664777
-
T. Gaj, C. A. Gersbach, C. F. Barbas 3rd, ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 31, 397-405 (2013). doi: 10.1016/j.tibtech.2013.04.004; pmid: 23664777
-
(2013)
Trends Biotechnol.
, vol.31
, pp. 397-405
-
-
Gaj, T.1
Gersbach, C.A.2
Barbas III, C.F.3
-
75
-
-
84864439768
-
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
-
doi: 10.1038/nmeth.2030; pmid: 22751204
-
T. Gaj, J. Guo, Y. Kato, S. J. Sirk, C. F. Barbas 3rd, Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Nat. Methods 9, 805-807 (2012). doi: 10.1038/nmeth.2030; pmid: 22751204
-
(2012)
Nat. Methods
, vol.9
, pp. 805-807
-
-
Gaj, T.1
Guo, J.2
Kato, Y.3
Sirk, S.J.4
Barbas III, C.F.5
-
76
-
-
84884856342
-
Cas9 as a versatile tool for engineering biology
-
doi: 10.1038/nmeth.2649; pmid: 24076990
-
P. Mali, K. M. Esvelt, G. M. Church, Cas9 as a versatile tool for engineering biology. Nat. Methods 10, 957-963 (2013). doi: 10.1038/nmeth.2649; pmid: 24076990
-
(2013)
Nat. Methods
, vol.10
, pp. 957-963
-
-
Mali, P.1
Esvelt, K.M.2
Church, G.M.3
-
77
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
doi: 10.1126/science.1232033; pmid: 23287722
-
P. Mali et al., RNA-guided human genome engineering via Cas9. Science 339, 823-826 (2013).doi: 10.1126/science.1232033; pmid: 23287722
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
-
78
-
-
84865574313
-
The convergence of cochlear implantation with induced pluripotent stem cell therapy
-
doi: 10.1007/s12015-011-9320-0; pmid: 21956409
-
N. Gunewardene, M. Dottori, B. A. Nayagam, The convergence of cochlear implantation with induced pluripotent stem cell therapy. Stem Cell Rev. 8, 741-754 (2012). doi: 10.1007/s12015-011-9320-0; pmid: 21956409
-
(2012)
Stem Cell Rev.
, vol.8
, pp. 741-754
-
-
Gunewardene, N.1
Dottori, M.2
Nayagam, B.A.3
-
79
-
-
84896786196
-
Optogenetic stimulation of the auditory pathway
-
doi: 10.1172/JCI69050; pmid: 24509078
-
V. H. Hernandez et al ., Optogenetic stimulation of the auditory pathway. J. Clin. Invest. 124, 1114-1129 (2014). doi: 10.1172/JCI69050; pmid: 24509078
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 1114-1129
-
-
Hernandez, V.H.1
-
80
-
-
34447626657
-
An in vitro model system to study gene therapy in the human inner ear
-
doi: 10.1038/sj.gt.3302980; pmid: 17568767
-
B. W. Kesser, G. T. Hashisaki, K. Fletcher, H. Eppard, J. R. Holt, An in vitro model system to study gene therapy in the human inner ear. Gene Ther. 14, 1121-1131 (2007). doi: 10.1038/sj.gt.3302980; pmid: 17568767
-
(2007)
Gene Ther.
, vol.14
, pp. 1121-1131
-
-
Kesser, B.W.1
Hashisaki, G.T.2
Fletcher, K.3
Eppard, H.4
Holt, J.R.5
-
81
-
-
0000996699
-
-
Oxford Univ. Press, New York
-
Y. Nelson, S. Kang, in Handbook of Physiology, The Nervous System, Sensory Processes (Oxford Univ. Press, New York, 1984), vol. 3, pp. 639-674.
-
(1984)
Handbook of Physiology, the Nervous System, Sensory Processes
, vol.3
, pp. 639-674
-
-
Nelson, Y.1
Kang, S.2
-
82
-
-
0017868523
-
A technique for preparation of cochlear specimens for assessment with the scanning electron microscope
-
doi: 10.3109/00016487809122718; pmid: 352089
-
I. M. Hunter-Duvar, A technique for preparation of cochlear specimens for assessment with the scanning electron microscope. Acta Otolaryngol. Suppl. 351, 3-23 (1978). doi: 10.3109/00016487809122718; pmid: 352089
-
(1978)
Acta Otolaryngol. Suppl.
, vol.351
, pp. 3-23
-
-
Hunter-Duvar, I.M.1
-
83
-
-
33845265640
-
The multiple-channel cochlear implant: The interface between sound and the central nervous system for hearing, speech, and language in deaf people-a personal perspective
-
doi: 10.1098/rstb.2005.1782; pmid: 16627295
-
G. M. Clark, The multiple-channel cochlear implant: the interface between sound and the central nervous system for hearing, speech, and language in deaf people-a personal perspective. Philos. Trans. R. Soc. London B Biol. Sci. 361, 791-810 (2006). doi: 10.1098/rstb.2005.1782; pmid: 16627295
-
(2006)
Philos. Trans. R. Soc. London B Biol. Sci.
, vol.361
, pp. 791-810
-
-
Clark, G.M.1
|