Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea

Stem Cell Reports

Volumn 2, Issue 3, 2014, Pages 311-322

  Bramhall, Naomi F ^a,b,c   Shi, Fuxin ^a,b   Arnold, Katrin ^d   Hochedlinger, Konrad ^d   Edge, Albert S B ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CRE RECOMBINASE; GAMMA SECRETASE; MYOSIN VIIA; NOTCH RECEPTOR; PROTEIN LGR5; TRANSCRIPTION FACTOR POU4F3; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; WNT PROTEIN; ALANINE; AZEPINE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; GENTAMICIN; LGR5 PROTEIN, MOUSE; N2-((2S)-2-(3,5-DIFLUOROPHENYL)-2-HYDROXYETHANOYL)-N1-((7S)-5-METHYL-6-OXO-6,7-DIHYDRO-5H-DIBENZO(B,D)AZEPIN-7-YL)-L-ALANINAMIDE; SECRETASE; TRANSCRIPTION FACTOR SOX; MARKER; N2 [2 (3,5 DIFLUOROPHENYL) 2 HYDROXYACETYL] N1 (6,7 DIHYDRO 5 METHYL 6 OXO 5H DIBENZ[B,D]AZEPIN 7 YL)ALANINAMIDE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CELL POPULATION; CELL REGENERATION; CELL TRANSDIFFERENTIATION; CELL VIABILITY; COCHLEA; COCHLEA INJURY; CONTROLLED STUDY; CORTI ORGAN; ENZYME INHIBITION; HAIR CELL; MITOSIS; MOUSE; NEWBORN; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WNT SIGNALING PATHWAY; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; METABOLISM; STEM CELL; TRANSGENIC MOUSE; CELL DAMAGE; HEARING IMPAIRMENT; IN VITRO STUDY; INNER EAR; INTESTINAL STEM CELL; MAMMAL; PERCEPTION DEAFNESS; POLYMERASE CHAIN REACTION; POSTNATAL DEVELOPMENT;

MAMMALIA;

ALANINE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; AZEPINES; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; COCHLEA; GENTAMICINS; HAIR CELLS, AUDITORY; MICE; MICE, TRANSGENIC; ORGAN OF CORTI; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NOTCH; SOXB1 TRANSCRIPTION FACTORS; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84896102205     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.01.008     Document Type: Article

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