메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages

Notch Signaling Limits Supporting Cell Plasticity in the Hair Cell-Damaged Early Postnatal Murine Cochlea

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN; NOTCH RECEPTOR; PRESTIN; PROTEIN HEY1; PROTEIN HEY2; PROTEIN HEYL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 84883318455     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073276     Document Type: Article
Times cited : (71)

References (79)
  • 1
    • 0030873162 scopus 로고    scopus 로고
    • Further evidence for supporting cell conversion in the damaged avian basilar papilla
    • Adler HJ, Komeda M, Raphael Y, (1997) Further evidence for supporting cell conversion in the damaged avian basilar papilla. Int J Dev Neurosci 15: 375-385.
    • (1997) Int J Dev Neurosci , vol.15 , pp. 375-385
    • Adler, H.J.1    Komeda, M.2    Raphael, Y.3
  • 2
    • 0024295746 scopus 로고
    • Hair cell regeneration after acoustic trauma in adult Coturnix quail
    • Ryals BM, Rubel EW, (1988) Hair cell regeneration after acoustic trauma in adult Coturnix quail. Science 240: 1774-1776.
    • (1988) Science , vol.240 , pp. 1774-1776
    • Ryals, B.M.1    Rubel, E.W.2
  • 3
    • 0023918917 scopus 로고
    • Regeneration of sensory hair cells after acoustic trauma
    • Corwin JT, Cotanche DA, (1988) Regeneration of sensory hair cells after acoustic trauma. Science 240: 1772-1774.
    • (1988) Science , vol.240 , pp. 1772-1774
    • Corwin, J.T.1    Cotanche, D.A.2
  • 4
    • 33745577647 scopus 로고    scopus 로고
    • Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
    • White PM, Doetzlhofer A, Lee YS, Groves AK, Segil N, (2006) Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature 441: 984-987.
    • (2006) Nature , vol.441 , pp. 984-987
    • White, P.M.1    Doetzlhofer, A.2    Lee, Y.S.3    Groves, A.K.4    Segil, N.5
  • 5
    • 84855387944 scopus 로고    scopus 로고
    • Intrinsic regenerative potential of murine cochlear supporting cells
    • Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, et al. (2011) Intrinsic regenerative potential of murine cochlear supporting cells. Sci Rep 1: 26.
    • (2011) Sci Rep , vol.1 , pp. 26
    • Sinkkonen, S.T.1    Chai, R.2    Jan, T.A.3    Hartman, B.H.4    Laske, R.D.5
  • 6
    • 84861448404 scopus 로고    scopus 로고
    • Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea
    • Chai R, Kuo B, Wang T, Liaw EJ, Xia A, et al. (2012) Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proc Natl Acad Sci U S A 109: 8167-8172.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 8167-8172
    • Chai, R.1    Kuo, B.2    Wang, T.3    Liaw, E.J.4    Xia, A.5
  • 7
    • 84863660179 scopus 로고    scopus 로고
    • Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea
    • Shi F, Kempfle JS, Edge AS, (2012) Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea. J Neurosci 32: 9639-9648.
    • (2012) J Neurosci , vol.32 , pp. 9639-9648
    • Shi, F.1    Kempfle, J.S.2    Edge, A.S.3
  • 8
    • 31444447881 scopus 로고    scopus 로고
    • Notch signalling in vertebrate neural development
    • Louvi A, Artavanis-Tsakonas S, (2006) Notch signalling in vertebrate neural development. Nat Rev Neurosci 7: 93-102.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 93-102
    • Louvi, A.1    Artavanis-Tsakonas, S.2
  • 9
    • 79952213043 scopus 로고    scopus 로고
    • Notch in the vertebrate nervous system: an old dog with new tricks
    • Pierfelice T, Alberi L, Gaiano N, (2011) Notch in the vertebrate nervous system: an old dog with new tricks. Neuron 69: 840-855.
    • (2011) Neuron , vol.69 , pp. 840-855
    • Pierfelice, T.1    Alberi, L.2    Gaiano, N.3
  • 11
    • 0034127584 scopus 로고    scopus 로고
    • Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
    • Zheng JL, Gao WQ, (2000) Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 3: 580-586.
    • (2000) Nat Neurosci , vol.3 , pp. 580-586
    • Zheng, J.L.1    Gao, W.Q.2
  • 14
    • 41549095020 scopus 로고    scopus 로고
    • Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development
    • Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, et al. (2008) Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol 8: 20.
    • (2008) BMC Dev Biol , vol.8 , pp. 20
    • Li, S.1    Mark, S.2    Radde-Gallwitz, K.3    Schlisner, R.4    Chin, M.T.5
  • 15
    • 79953029369 scopus 로고    scopus 로고
    • Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development
    • Tateya T, Imayoshi I, Tateya I, Ito J, Kageyama R, (2011) Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev Biol 352: 329-340.
    • (2011) Dev Biol , vol.352 , pp. 329-340
    • Tateya, T.1    Imayoshi, I.2    Tateya, I.3    Ito, J.4    Kageyama, R.5
  • 16
    • 0033710329 scopus 로고    scopus 로고
    • Hes1 is a negative regulator of inner ear hair cell differentiation
    • Zheng JL, Shou J, Guillemot F, Kageyama R, Gao WQ, (2000) Hes1 is a negative regulator of inner ear hair cell differentiation. Development Nov 127: 4551-4560.
    • (2000) Development Nov , vol.127 , pp. 4551-4560
    • Zheng, J.L.1    Shou, J.2    Guillemot, F.3    Kageyama, R.4    Gao, W.Q.5
  • 17
    • 0035400075 scopus 로고    scopus 로고
    • Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear
    • Zine A, Aubert A, Qiu J, Therianos S, Guillemot F, et al. (2001) Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J Neurosci 21: 4712-4720.
    • (2001) J Neurosci , vol.21 , pp. 4712-4720
    • Zine, A.1    Aubert, A.2    Qiu, J.3    Therianos, S.4    Guillemot, F.5
  • 18
    • 27644446538 scopus 로고    scopus 로고
    • The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear
    • Kiernan AE, Cordes R, Kopan R, Gossler A, Gridley T, (2005) The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 132: 4353-4362.
    • (2005) Development , vol.132 , pp. 4353-4362
    • Kiernan, A.E.1    Cordes, R.2    Kopan, R.3    Gossler, A.4    Gridley, T.5
  • 19
    • 33646164664 scopus 로고    scopus 로고
    • Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear
    • Brooker R, Hozumi K, Lewis J (2006) Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development.
    • (2006) Development
    • Brooker, R.1    Hozumi, K.2    Lewis, J.3
  • 20
    • 0036727125 scopus 로고    scopus 로고
    • Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
    • Fortini ME, (2002) Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling. Nat Rev Mol Cell Biol 3: 673-684.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 673-684
    • Fortini, M.E.1
  • 21
    • 33750328964 scopus 로고    scopus 로고
    • COUP-TFI controls Notch regulation of hair cell and support cell differentiation
    • Tang LS, Alger HM, Pereira FA, (2006) COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development 133: 3683-3693.
    • (2006) Development , vol.133 , pp. 3683-3693
    • Tang, L.S.1    Alger, H.M.2    Pereira, F.A.3
  • 22
    • 34250000827 scopus 로고    scopus 로고
    • Multiple roles of Notch signaling in cochlear development
    • Takebayashi S, Yamamoto N, Yabe D, Fukuda H, Kojima K, et al. (2007) Multiple roles of Notch signaling in cochlear development. Dev Biol 307: 165-178.
    • (2007) Dev Biol , vol.307 , pp. 165-178
    • Takebayashi, S.1    Yamamoto, N.2    Yabe, D.3    Fukuda, H.4    Kojima, K.5
  • 23
    • 30744455741 scopus 로고    scopus 로고
    • Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas
    • Yamamoto N, Tanigaki K, Tsuji M, Yabe D, Ito J, et al. (2006) Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med (Berl) 84: 37-45.
    • (2006) J Mol Med (Berl) , vol.84 , pp. 37-45
    • Yamamoto, N.1    Tanigaki, K.2    Tsuji, M.3    Yabe, D.4    Ito, J.5
  • 24
    • 58149477862 scopus 로고    scopus 로고
    • Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
    • Doetzlhofer A, Basch ML, Ohyama T, Gessler M, Groves AK, et al. (2009) Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell 16: 58-69.
    • (2009) Dev Cell , vol.16 , pp. 58-69
    • Doetzlhofer, A.1    Basch, M.L.2    Ohyama, T.3    Gessler, M.4    Groves, A.K.5
  • 25
    • 80054787667 scopus 로고    scopus 로고
    • Effects of DAPT and Atoh1 overexpression on hair cell production and hair bundle orientation in cultured Organ of Corti from neonatal rats
    • Zhao LD, Guo WW, Lin C, Li LX, Sun JH, et al. (2011) Effects of DAPT and Atoh1 overexpression on hair cell production and hair bundle orientation in cultured Organ of Corti from neonatal rats. PLoS One 6: e23729.
    • (2011) PLoS One , vol.6
    • Zhao, L.D.1    Guo, W.W.2    Lin, C.3    Li, L.X.4    Sun, J.H.5
  • 26
    • 84872173335 scopus 로고    scopus 로고
    • Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma
    • Mizutari K, Fujioka M, Hosoya M, Bramhall N, Okano HJ, et al. (2013) Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron 77: 58-69.
    • (2013) Neuron , vol.77 , pp. 58-69
    • Mizutari, K.1    Fujioka, M.2    Hosoya, M.3    Bramhall, N.4    Okano, H.J.5
  • 28
    • 33645758812 scopus 로고    scopus 로고
    • The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear
    • Kiernan AE, Xu J, Gridley T, (2006) The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear. PLoS Genet 2: e4.
    • (2006) PLoS Genet , vol.2
    • Kiernan, A.E.1    Xu, J.2    Gridley, T.3
  • 29
    • 0033845467 scopus 로고    scopus 로고
    • Notch signaling regulates the pattern of auditory hair cell differentiation in mammals
    • Zine A, Van De Water TR, de Ribaupierre F, (2000) Notch signaling regulates the pattern of auditory hair cell differentiation in mammals. Development 127: 3373-3383.
    • (2000) Development , vol.127 , pp. 3373-3383
    • Zine, A.1    Van De Water, T.R.2    de Ribaupierre, F.3
  • 31
    • 0242401835 scopus 로고    scopus 로고
    • A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
    • Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, et al. (2003) A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425: 917-925.
    • (2003) Nature , vol.425 , pp. 917-925
    • Gong, S.1    Zheng, C.2    Doughty, M.L.3    Losos, K.4    Didkovsky, N.5
  • 32
    • 34948856826 scopus 로고    scopus 로고
    • Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
    • Srinivasan RS, Dillard ME, Lagutin OV, Lin FJ, Tsai S, et al. (2007) Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev 21: 2422-2432.
    • (2007) Genes Dev , vol.21 , pp. 2422-2432
    • Srinivasan, R.S.1    Dillard, M.E.2    Lagutin, O.V.3    Lin, F.J.4    Tsai, S.5
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 46449091667 scopus 로고    scopus 로고
    • Aminoglycoside induced ototoxicity
    • Guthrie OW, (2008) Aminoglycoside induced ototoxicity. Toxicology 249: 91-96.
    • (2008) Toxicology , vol.249 , pp. 91-96
    • Guthrie, O.W.1
  • 36
    • 59449109623 scopus 로고    scopus 로고
    • Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea
    • Chen FQ, Schacht J, Sha SH, (2009) Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. J Neurochem 108: 1226-1236.
    • (2009) J Neurochem , vol.108 , pp. 1226-1236
    • Chen, F.Q.1    Schacht, J.2    Sha, S.H.3
  • 37
    • 33750290919 scopus 로고    scopus 로고
    • Regulation of cell fate in the sensory epithelia of the inner ear
    • Kelley MW, (2006) Regulation of cell fate in the sensory epithelia of the inner ear. Nat Rev Neurosci 7: 837-849.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 837-849
    • Kelley, M.W.1
  • 38
    • 33947326091 scopus 로고    scopus 로고
    • Cell division and maintenance of epithelial integrity in the deafened auditory epithelium
    • Kim YH, Raphael Y, (2007) Cell division and maintenance of epithelial integrity in the deafened auditory epithelium. Cell Cycle 6: 612-619.
    • (2007) Cell Cycle , vol.6 , pp. 612-619
    • Kim, Y.H.1    Raphael, Y.2
  • 39
    • 84856396559 scopus 로고    scopus 로고
    • Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea
    • Taylor RR, Jagger DJ, Forge A, (2012) Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea. PLoS One 7: e30577.
    • (2012) PLoS One , vol.7
    • Taylor, R.R.1    Jagger, D.J.2    Forge, A.3
  • 40
    • 0034212915 scopus 로고    scopus 로고
    • A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea
    • Zhang N, Martin GV, Kelley MW, Gridley T, (2000) A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea. Curr Biol 10: 659-662.
    • (2000) Curr Biol , vol.10 , pp. 659-662
    • Zhang, N.1    Martin, G.V.2    Kelley, M.W.3    Gridley, T.4
  • 42
    • 34548567099 scopus 로고    scopus 로고
    • Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea
    • Jacques BE, Montcouquiol ME, Layman EM, Lewandoski M, Kelley MW, (2007) Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development 134: 3021-3029.
    • (2007) Development , vol.134 , pp. 3021-3029
    • Jacques, B.E.1    Montcouquiol, M.E.2    Layman, E.M.3    Lewandoski, M.4    Kelley, M.W.5
  • 43
    • 33846933074 scopus 로고    scopus 로고
    • Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti
    • Hayashi T, Cunningham D, Bermingham-McDonogh O, (2007) Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn 236: 525-533.
    • (2007) Dev Dyn , vol.236 , pp. 525-533
    • Hayashi, T.1    Cunningham, D.2    Bermingham-McDonogh, O.3
  • 44
    • 16244423015 scopus 로고    scopus 로고
    • Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling
    • Shim K, Minowada G, Coling DE, Martin GR, (2005) Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev Cell 8: 553-564.
    • (2005) Dev Cell , vol.8 , pp. 553-564
    • Shim, K.1    Minowada, G.2    Coling, D.E.3    Martin, G.R.4
  • 45
    • 40949091386 scopus 로고    scopus 로고
    • Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea
    • Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, et al. (2008) Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol 316: 87-99.
    • (2008) Dev Biol , vol.316 , pp. 87-99
    • Hayashi, T.1    Kokubo, H.2    Hartman, B.H.3    Ray, C.A.4    Reh, T.A.5
  • 46
    • 57449114544 scopus 로고    scopus 로고
    • Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea
    • Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, et al. (2008) Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A 105: 18396-18401.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18396-18401
    • Dabdoub, A.1    Puligilla, C.2    Jones, J.M.3    Fritzsch, B.4    Cheah, K.S.5
  • 47
    • 77957663412 scopus 로고    scopus 로고
    • Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear
    • Pan W, Jin Y, Stanger B, Kiernan AE, (2010) Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear. Proc Natl Acad Sci U S A 107: 15798-15803.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15798-15803
    • Pan, W.1    Jin, Y.2    Stanger, B.3    Kiernan, A.E.4
  • 48
    • 77957654320 scopus 로고    scopus 로고
    • Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
    • Hartman BH, Reh TA, Bermingham-McDonogh O, (2010) Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. Proc Natl Acad Sci U S A 107: 15792-15797.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15792-15797
    • Hartman, B.H.1    Reh, T.A.2    Bermingham-McDonogh, O.3
  • 49
    • 0030802157 scopus 로고    scopus 로고
    • Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development
    • Xiang M, Gan L, Li D, Chen ZY, Zhou L, et al. (1997) Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A 94: 9445-9450.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9445-9450
    • Xiang, M.1    Gan, L.2    Li, D.3    Chen, Z.Y.4    Zhou, L.5
  • 50
    • 0028803112 scopus 로고
    • The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
    • Avraham KB, Hasson T, Steel KP, Kingsley DM, Russell LB, et al. (1995) The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nat Genet 11: 369-375.
    • (1995) Nat Genet , vol.11 , pp. 369-375
    • Avraham, K.B.1    Hasson, T.2    Steel, K.P.3    Kingsley, D.M.4    Russell, L.B.5
  • 51
    • 1342344617 scopus 로고    scopus 로고
    • Expression of alpha and beta parvalbumin is differentially regulated in the rat organ of corti during development
    • Yang D, Thalmann I, Thalmann R, Simmons DD, (2004) Expression of alpha and beta parvalbumin is differentially regulated in the rat organ of corti during development. J Neurobiol 58: 479-492.
    • (2004) J Neurobiol , vol.58 , pp. 479-492
    • Yang, D.1    Thalmann, I.2    Thalmann, R.3    Simmons, D.D.4
  • 53
    • 84883405771 scopus 로고    scopus 로고
    • Beyond generalized hair cells: Molecular cues for hair cell types
    • Jahan I, Pan N, Kersigo J, Fritzsch B (2012) Beyond generalized hair cells: Molecular cues for hair cell types. Hear Res.
    • (2012) Hear Res
    • Jahan, I.1    Pan, N.2    Kersigo, J.3    Fritzsch, B.4
  • 54
    • 33749994043 scopus 로고    scopus 로고
    • Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse
    • Roux I, Safieddine S, Nouvian R, Grati M, Simmler MC, et al. (2006) Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127: 277-289.
    • (2006) Cell , vol.127 , pp. 277-289
    • Roux, I.1    Safieddine, S.2    Nouvian, R.3    Grati, M.4    Simmler, M.C.5
  • 55
    • 33748910801 scopus 로고    scopus 로고
    • Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia
    • Kruger M, Schmid T, Kruger S, Bober E, Braun T, (2006) Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci 24: 1581-1590.
    • (2006) Eur J Neurosci , vol.24 , pp. 1581-1590
    • Kruger, M.1    Schmid, T.2    Kruger, S.3    Bober, E.4    Braun, T.5
  • 56
    • 0036337481 scopus 로고    scopus 로고
    • The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
    • Chen P, Johnson JE, Zoghbi HY, Segil N, (2002) The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination. Development May 129: 2495-2505.
    • (2002) Development May , vol.129 , pp. 2495-2505
    • Chen, P.1    Johnson, J.E.2    Zoghbi, H.Y.3    Segil, N.4
  • 57
    • 84055217017 scopus 로고    scopus 로고
    • Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes
    • Kawashima Y, Geleoc GS, Kurima K, Labay V, Lelli A, et al. (2011) Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J Clin Invest 121: 4796-4809.
    • (2011) J Clin Invest , vol.121 , pp. 4796-4809
    • Kawashima, Y.1    Geleoc, G.S.2    Kurima, K.3    Labay, V.4    Lelli, A.5
  • 58
    • 20244389145 scopus 로고    scopus 로고
    • Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus
    • Verpy E, Masmoudi S, Zwaenepoel I, Leibovici M, Hutchin TP, et al. (2001) Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus. Nat Genet 29: 345-349.
    • (2001) Nat Genet , vol.29 , pp. 345-349
    • Verpy, E.1    Masmoudi, S.2    Zwaenepoel, I.3    Leibovici, M.4    Hutchin, T.P.5
  • 59
    • 0034672784 scopus 로고    scopus 로고
    • Expression and localization of prestin and the sugar transporter GLUT-5 during development of electromotility in cochlear outer hair cells
    • Belyantseva IA, Adler HJ, Curi R, Frolenkov GI, Kachar B, (2000) Expression and localization of prestin and the sugar transporter GLUT-5 during development of electromotility in cochlear outer hair cells. J Neurosci 20: RC116.
    • (2000) J Neurosci , vol.20
    • Belyantseva, I.A.1    Adler, H.J.2    Curi, R.3    Frolenkov, G.I.4    Kachar, B.5
  • 60
    • 77955683363 scopus 로고    scopus 로고
    • Oncomodulin identifies different hair cell types in the mammalian inner ear
    • Simmons DD, Tong B, Schrader AD, Hornak AJ, (2010) Oncomodulin identifies different hair cell types in the mammalian inner ear. J Comp Neurol 518: 3785-3802.
    • (2010) J Comp Neurol , vol.518 , pp. 3785-3802
    • Simmons, D.D.1    Tong, B.2    Schrader, A.D.3    Hornak, A.J.4
  • 61
    • 77951656332 scopus 로고    scopus 로고
    • In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice
    • Yu Y, Weber T, Yamashita T, Liu Z, Valentine MB, et al. (2010) In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice. J Neurosci 30: 5927-5936.
    • (2010) J Neurosci , vol.30 , pp. 5927-5936
    • Yu, Y.1    Weber, T.2    Yamashita, T.3    Liu, Z.4    Valentine, M.B.5
  • 62
    • 0037731494 scopus 로고    scopus 로고
    • Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells
    • Marcotti W, Johnson SL, Holley MC, Kros CJ, (2003) Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells. J Physiol 548: 383-400.
    • (2003) J Physiol , vol.548 , pp. 383-400
    • Marcotti, W.1    Johnson, S.L.2    Holley, M.C.3    Kros, C.J.4
  • 63
    • 0033230252 scopus 로고    scopus 로고
    • Developmental expression of the potassium current IK, n contributes to maturation of mouse outer hair cells
    • Marcotti W, Kros CJ, (1999) Developmental expression of the potassium current IK, n contributes to maturation of mouse outer hair cells. J Physiol 520 Pt 3: 653-660.
    • (1999) J Physiol 520 Pt , vol.3 , pp. 653-660
    • Marcotti, W.1    Kros, C.J.2
  • 65
    • 35948971774 scopus 로고    scopus 로고
    • The origin of spontaneous activity in the developing auditory system
    • Tritsch NX, Yi E, Gale JE, Glowatzki E, Bergles DE, (2007) The origin of spontaneous activity in the developing auditory system. Nature 450: 50-55.
    • (2007) Nature , vol.450 , pp. 50-55
    • Tritsch, N.X.1    Yi, E.2    Gale, J.E.3    Glowatzki, E.4    Bergles, D.E.5
  • 66
    • 0031424914 scopus 로고    scopus 로고
    • Sodium current expression during postnatal development of rat outer hair cells
    • Oliver D, Plinkert P, Zenner HP, Ruppersberg JP, (1997) Sodium current expression during postnatal development of rat outer hair cells. Pflugers Arch 434: 772-778.
    • (1997) Pflugers Arch , vol.434 , pp. 772-778
    • Oliver, D.1    Plinkert, P.2    Zenner, H.P.3    Ruppersberg, J.P.4
  • 67
    • 84859641744 scopus 로고    scopus 로고
    • Functional assembly of mammalian cochlear hair cells
    • Marcotti W, (2012) Functional assembly of mammalian cochlear hair cells. Exp Physiol 97: 438-451.
    • (2012) Exp Physiol , vol.97 , pp. 438-451
    • Marcotti, W.1
  • 68
    • 33747080821 scopus 로고    scopus 로고
    • The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea
    • Glowatzki E, Cheng N, Hiel H, Yi E, Tanaka K, et al. (2006) The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea. J Neurosci 26: 7659-7664.
    • (2006) J Neurosci , vol.26 , pp. 7659-7664
    • Glowatzki, E.1    Cheng, N.2    Hiel, H.3    Yi, E.4    Tanaka, K.5
  • 69
    • 0032537773 scopus 로고    scopus 로고
    • Expression of a potassium current in inner hair cells during development of hearing in mice
    • Kros CJ, Ruppersberg JP, Rusch A, (1998) Expression of a potassium current in inner hair cells during development of hearing in mice. Nature 394: 281-284.
    • (1998) Nature , vol.394 , pp. 281-284
    • Kros, C.J.1    Ruppersberg, J.P.2    Rusch, A.3
  • 70
    • 10944252852 scopus 로고    scopus 로고
    • Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear
    • Geleoc GS, Risner JR, Holt JR, (2004) Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear. J Neurosci 24: 11148-11159.
    • (2004) J Neurosci , vol.24 , pp. 11148-11159
    • Geleoc, G.S.1    Risner, J.R.2    Holt, J.R.3
  • 71
    • 72249118433 scopus 로고    scopus 로고
    • Supporting cell characteristics in long-deafened aged mouse ears
    • Oesterle EC, Campbell S, (2009) Supporting cell characteristics in long-deafened aged mouse ears. J Assoc Res Otolaryngol 10: 525-544.
    • (2009) J Assoc Res Otolaryngol , vol.10 , pp. 525-544
    • Oesterle, E.C.1    Campbell, S.2
  • 72
    • 36048982581 scopus 로고    scopus 로고
    • Non-sensory cells in the deafened organ of Corti: approaches for repair
    • Raphael Y, Kim YH, Osumi Y, Izumikawa M, (2007) Non-sensory cells in the deafened organ of Corti: approaches for repair. Int J Dev Biol 51: 649-654.
    • (2007) Int J Dev Biol , vol.51 , pp. 649-654
    • Raphael, Y.1    Kim, Y.H.2    Osumi, Y.3    Izumikawa, M.4
  • 73
    • 77956798907 scopus 로고    scopus 로고
    • Supporting cells eliminate dying sensory hair cells to maintain epithelial integrity in the avian inner ear
    • Bird JE, Daudet N, Warchol ME, Gale JE, (2010) Supporting cells eliminate dying sensory hair cells to maintain epithelial integrity in the avian inner ear. J Neurosci 30: 12545-12556.
    • (2010) J Neurosci , vol.30 , pp. 12545-12556
    • Bird, J.E.1    Daudet, N.2    Warchol, M.E.3    Gale, J.E.4
  • 74
    • 77954757692 scopus 로고    scopus 로고
    • Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear
    • Hartman BH, Nelson BR, Reh TA, Bermingham-McDonogh O, (2010) Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear. J Assoc Res Otolaryngol 11: 187-201.
    • (2010) J Assoc Res Otolaryngol , vol.11 , pp. 187-201
    • Hartman, B.H.1    Nelson, B.R.2    Reh, T.A.3    Bermingham-McDonogh, O.4
  • 75
    • 84860683510 scopus 로고    scopus 로고
    • Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression
    • Liu Z, Dearman JA, Cox BC, Walters BJ, Zhang L, et al. (2012) Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression. J Neurosci 32: 6600-6610.
    • (2012) J Neurosci , vol.32 , pp. 6600-6610
    • Liu, Z.1    Dearman, J.A.2    Cox, B.C.3    Walters, B.J.4    Zhang, L.5
  • 76
    • 57649240258 scopus 로고    scopus 로고
    • Spontaneous hair cell regeneration in the mouse utricle following gentamicin ototoxicity
    • Kawamoto K, Izumikawa M, Beyer LA, Atkin GM, Raphael Y, (2009) Spontaneous hair cell regeneration in the mouse utricle following gentamicin ototoxicity. Hear Res 247: 17-26.
    • (2009) Hear Res , vol.247 , pp. 17-26
    • Kawamoto, K.1    Izumikawa, M.2    Beyer, L.A.3    Atkin, G.M.4    Raphael, Y.5
  • 77
    • 84867749413 scopus 로고    scopus 로고
    • Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin
    • Golub JS, Tong L, Ngyuen TB, Hume CR, Palmiter RD, et al. (2012) Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin. J Neurosci 32: 15093-15105.
    • (2012) J Neurosci , vol.32 , pp. 15093-15105
    • Golub, J.S.1    Tong, L.2    Ngyuen, T.B.3    Hume, C.R.4    Palmiter, R.D.5
  • 78
    • 80054932116 scopus 로고    scopus 로고
    • Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles
    • Lin V, Golub JS, Nguyen TB, Hume CR, Oesterle EC, et al. (2011) Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles. J Neurosci 31: 15329-15339.
    • (2011) J Neurosci , vol.31 , pp. 15329-15339
    • Lin, V.1    Golub, J.S.2    Nguyen, T.B.3    Hume, C.R.4    Oesterle, E.C.5
  • 79
    • 84860657802 scopus 로고    scopus 로고
    • Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal Mammalian cochlea in vivo
    • Kelly MC, Chang Q, Pan A, Lin X, Chen P, (2012) Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal Mammalian cochlea in vivo. J Neurosci 32: 6699-6710.
    • (2012) J Neurosci , vol.32 , pp. 6699-6710
    • Kelly, M.C.1    Chang, Q.2    Pan, A.3    Lin, X.4    Chen, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.