Inner ear gene transfection in neonatal mice using adeno-associated viral vector: A comparison of two approaches

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Xia, Li ^a   Yin, Shankai ^a   Wang, Jian ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PARVOVIRUS VECTOR; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLINICAL PROTOCOL; COCHLEA FENESTRA; CONTROLLED STUDY; GENETIC TRANSFECTION; HAIR CELL; HEARING ACUITY; INNER EAR; INTERMETHOD COMPARISON; LABORATORY; MORTALITY; MOUSE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PROCESS OPTIMIZATION; PUNCTURE; SAFETY; SCALA TYMPANI; SURVIVAL RATE; VIRAL GENE DELIVERY SYSTEM; VIRUS MUTATION;

ANIMALS; ANIMALS, NEWBORN; DEPENDOVIRUS; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; INJECTIONS; LABYRINTH DISEASES; MICE; MICROSCOPY, CONFOCAL; ROUND WINDOW, EAR; SCALA TYMPANI; TRANSFECTION;

EID: 84865087884     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043218     Document Type: Article

References (39)

1. Keenan JF, (1990) Human gene therapy: an ethical advance? America (NY) 163: 262-263.
2. Agrup C, Gleeson M, Rudge P, (2007) The inner ear and the neurologist. J Neurol Neurosurg Psychiatry 78: 114-122.
3. Cooper LB, Chan DK, Roediger FC, Shaffer BR, Fraser JF, et al. (2006) AAV-mediated delivery of the caspase inhibitor XIAP protects against cisplatin ototoxicity. Otol Neurotol 27: 484-490.
4. Gratton MA, Salvi RJ, Kamen BA, Saunders SS, (1990) Interaction of cisplatin and noise on the peripheral auditory system. Hear Res 50: 211-223.
5. Lalwani AK, Walsh BJ, Reilly PG, Muzyczka N, Mhatre AN, (1996) Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig. Gene Ther 3: 588-592.
6. Marazita ML, Ploughman LM, Rawlings B, Remington E, Arnos KS, et al. (1993) Genetic epidemiological studies of early-onset deafness in the U.S. school-age population. Am J Med Genet 46: 486-491.
7. Morton NE, (1991) Genetic epidemiology of hearing impairment. Ann N Y Acad Sci 630: 16-31.
8. Newton VE (1985) Aetiology of bilateral sensori-neural hearing loss in young children. J Laryngol Otol Suppl 10: 1-57.
9. Ahmad S, Tang W, Chang Q, Qu Y, Hibshman J, et al. (2007) Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A 104: 1337-1341.
10. Coutelle C, Themis M, Waddington SN, Buckley SM, Gregory LG, et al. (2005) Gene therapy progress and prospects: fetal gene therapy-irst proofs of concept-ome adverse effects. Gene Ther 12: 1601-1607.
11. Wenzel GI, Xia A, Funk E, Evans MB, Palmer DJ, et al. (2007) Helper-dependent adenovirus-mediated gene transfer into the adult mouse cochlea. Otol Neurotol 28: 1100-1108.
12. Konishi M, Kawamoto K, Izumikawa M, Kuriyama H, Yamashita T, (2008) Gene transfer into guinea pig cochlea using adeno-associated virus vectors. J Gene Med 10: 610-618.
13. Pietola L, Aarnisalo AA, Joensuu J, Pellinen R, Wahlfors J, et al. (2008) HOX-GFP and WOX-GFP lentivirus vectors for inner ear gene transfer. Acta Otolaryngol 128: 613-620.
14. Carnicero E, Knipper M, Tan J, Alonso MT, Schimmang T, (2002) Herpes simplex virus type 1-mediated transfer of neurotrophin-3 stimulates survival of chicken auditory sensory neurons. Neurosci Lett 321: 149-152.
15. Zhong L, Li B, Jayandharan G, Mah CS, Govindasamy L, et al. (2008) Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression. Virology 381: 194-202.
16. Wang H, Murphy R, Taaffe D, Yin S, Xia L, et al. (2011) Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane. Gene Ther. 2011/06/24 ed.
17. Friedman LM, Dror AA, Avraham KB, (2007) Mouse models to study inner ear development and hereditary hearing loss. Int J Dev Biol 51: 609-631.
18. Dror AA, Avraham KB, (2009) Hearing loss: mechanisms revealed by genetics and cell biology. Annu Rev Genet 43: 411-437.
19. Richardson GP, de Monvel JB, Petit C, (2011) How the genetics of deafness illuminates auditory physiology. Annu Rev Physiol 73: 311-334.
20. Chang EH, Van Camp G, Smith RJ, (2003) The role of connexins in human disease. Ear Hear 24: 314-323.
21. Cohen-Salmon M, Ott T, Michel V, Hardelin JP, Perfettini I, et al. (2002) Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death. Curr Biol 12: 1106-1111.
22. Nickel R, Forge A, (2008) Gap junctions and connexins in the inner ear: their roles in homeostasis and deafness. Curr Opin Otolaryngol Head Neck Surg 16: 452-457.
23. Lv P, Wei D, Yamoah EN, (2010) Kv7-type channel currents in spiral ganglion neurons: involvement in sensorineural hearing loss. J Biol Chem 285: 34699-34707.
24. Leibovici M, Safieddine S, Petit C, (2008) Mouse models for human hereditary deafness. Curr Top Dev Biol 84: 385-429.
25. Teubner B, Michel V, Pesch J, Lautermann J, Cohen-Salmon M, et al. (2003) Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential. Hum Mol Genet 12: 13-21.
26. Iizuka T, Kanzaki S, Mochizuki H, Inoshita A, Narui Y, et al. (2008) Noninvasive in vivo delivery of transgene via adeno-associated virus into supporting cells of the neonatal mouse cochlea. Hum Gene Ther 19: 384-390.
27. Zhong L, Li B, Mah CS, Govindasamy L, Agbandje-McKenna M, et al. (2008) Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses. Proc Natl Acad Sci U S A 105: 7827-7832.
28. Mann MA, Kinsley C, Broida J, Svare B, (1983) Infanticide exhibited by female mice: genetic, developmental and hormonal influences. Physiol Behav 30: 697-702.
29. Svare B, Kinsley CH, Mann MA, Broida J, (1984) Infanticide: accounting for genetic variation in mice. Physiol Behav 33: 137-152.
30. Jero J, Mhatre AN, Tseng CJ, Stern RE, Coling DE, et al. (2001) Cochlear gene delivery through an intact round window membrane in mouse. Hum Gene Ther 12: 539-548.
31. Anderson DR, Mitcheltree LW, Brobst DE, Byers SL, Merz DF, et al. (2002) A vapor exposure model for neonatal mice. Toxicol Mech Methods 12: 59-70.
32. Kilpatrick LA, Li Q, Yang J, Goddard JC, Fekete DM, et al. (2011) Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear. Gene Ther 18: 569-578.
33. Imamura S, Adams JC, (2003) Distribution of gentamicin in the guinea pig inner ear after local or systemic application. J Assoc Res Otolaryngol 4: 176-195.
34. Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, et al. (2007) Structure of adeno-associated virus serotype 8, a gene therapy vector. J Virol 81: 12260-12271.
35. Kimura RS, (1975) The ultrastructure of the organ of Corti. Int Rev Cytol 42: 173-222.
36. Nadol JB Jr, (1978) Intercellular junctions in the organ of Corti. Ann Otol Rhinol Laryngol 87: 70-80.
37. Fritzsch B, Farinas I, Reichardt LF, (1997) Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in a region-specific fashion. J Neurosci 17: 6213-6225.
38. Salt AN, Kellner C, Hale S, (2003) Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid. Hear Res 182: 24-33.
39. Thorne M, Salt AN, DeMott JE, Henson MM, Henson OW Jr, et al. (1999) Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images. Laryngoscope 109: 1661-1668.