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Volumn 18, Issue 6, 2011, Pages 569-578

Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear

Author keywords

AAV vectors; auditory nerves; hearing loss; scala media; sensory hair cells

Indexed keywords

ADENO ASSOCIATED VIRUS 1 VECTOR; ADENO ASSOCIATED VIRUS 2 VECTOR; ADENO ASSOCIATED VIRUS 5 VECTOR; ADENO ASSOCIATED VIRUS 6 VECTOR; ADENO ASSOCIATED VIRUS 8 VECTOR; GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 79958287787     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2010.175     Document Type: Article
Times cited : (94)

References (62)
  • 1
    • 0027976601 scopus 로고
    • Cell division in the gerbil cochlea after acoustic trauma
    • Roberson DW, Rubel EW. Cell division in the gerbil cochlea after acoustic trauma. Am J Otol 1994; 15: 28-34. (Pubitemid 24034513)
    • (1994) American Journal of Otology , vol.15 , Issue.1 , pp. 28-34
    • Roberson, D.W.1    Rubel, E.W.2
  • 2
    • 0032915922 scopus 로고    scopus 로고
    • Cell proliferation in spiral ligament of mouse cochlea damaged by dihydrostreptomycin sulfate
    • DOI 10.1080/00016489950181323
    • Yamashita H, Shimogori H, Sugahara K, Takahashi M. Cell proliferation in spiral ligament of mouse cochlea damaged by dihydrostreptomycin sulfate. Acta Otolaryngol 1999; 119: 322-325. (Pubitemid 29227396)
    • (1999) Acta Oto-Laryngologica , vol.119 , Issue.3 , pp. 322-325
    • Yamashita, H.1    Shimogori, H.2    Sugahara, K.3    Takahashi, M.4
  • 4
    • 67649525809 scopus 로고    scopus 로고
    • Feathers and fins: Non-mammalian models for hair cell regeneration
    • Brignull HR, Raible DW, Stone JS. Feathers and fins: non-mammalian models for hair cell regeneration. Brain Res 2009; 1277: 12-23.
    • (2009) Brain Res , vol.1277 , pp. 12-23
    • Brignull, H.R.1    Raible, D.W.2    Stone, J.S.3
  • 5
    • 77951632470 scopus 로고    scopus 로고
    • The challenge of hair cell regeneration
    • Groves AK. The challenge of hair cell regeneration. Exp Biol Med (Maywood) 2010; 235: 434-446.
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 434-446
    • Groves, A.K.1
  • 7
    • 33846630878 scopus 로고    scopus 로고
    • Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer
    • DOI 10.1097/MAO.0b013e31802b3225, PII 0012949220070200000014
    • Staecker H, Praetorius M, Baker K, Brough DE. Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer. Otol Neurotol 2007; 28: 223-231. (Pubitemid 46175126)
    • (2007) Otology and Neurotology , vol.28 , Issue.2 , pp. 223-231
    • Staecker, H.1    Praetorius, M.2    Baker, K.3    Brough, D.E.4
  • 8
    • 52949112282 scopus 로고    scopus 로고
    • Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
    • Gubbels SP, Woessner DW, Mitchell JC, Ricci AJ, Brigande JV. Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 2008; 455: 537-541.
    • (2008) Nature , vol.455 , pp. 537-541
    • Gubbels, S.P.1    Woessner, D.W.2    Mitchell, J.C.3    Ricci, A.J.4    Brigande, J.V.5
  • 9
    • 0029741373 scopus 로고    scopus 로고
    • Development of in vivo gene therapy for hearing disorders: Introduction of adeno-associated virus into the cochlea of the guinea pig
    • Lalwani AK, Walsh BJ, Reilly PG, Muzyczka N, Mhatre AN. Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig. Gene Therapy 1996; 3: 588-592. (Pubitemid 26258273)
    • (1996) Gene Therapy , vol.3 , Issue.7 , pp. 588-592
    • Lalwani, A.K.1    Walsh, B.J.2    Reilly, P.G.3    Muzyczka, N.4    Mhatre, A.N.5
  • 10
    • 0030794178 scopus 로고    scopus 로고
    • Transfection of neonatal rat cochlear cells in vitro with an adenovirus vector
    • DOI 10.1016/S0736-5748(96)00114-1, PII S0736574896001141
    • Dazert S, Battaglia A, Ryan AF. Transfection of neo-natal rat cochlear cells in vitro with an adenovirus vector. Int J Dev Neurosci 1997; 15: 595-600. (Pubitemid 27332109)
    • (1997) International Journal of Developmental Neuroscience , vol.15 , Issue.4-5 , pp. 595-600
    • Dazert, S.1    Battaglia, A.2    Ryan, A.F.3
  • 11
    • 0031977473 scopus 로고    scopus 로고
    • Expression of adeno-associated virus integrated transgene within the mammalian vestibular organs
    • Lalwani AK, Walsh BJ, Carvalho GJ, Muzyczka N, Mhatre AN. Expression of adenoassociated virus integrated transgene within the mammalian vestibular organs. Am J Otol 1998; 19: 390-395. (Pubitemid 28196827)
    • (1998) American Journal of Otology , vol.19 , Issue.3 , pp. 390-395
    • Lalwani, A.K.1    Walsh, B.J.2    Carvalho, G.J.3    Muzyczka, N.4    Mhatre, A.N.5
  • 12
    • 0031052597 scopus 로고    scopus 로고
    • In vivo gene transfer into the embryonic inner ear using retroviral vectors
    • Kiernan AE, Fekete DM. In vivo gene transfer into the embryonic inner ear using retroviral vectors. Audiol Neurootol 1997; 2: 12-24. (Pubitemid 27083567)
    • (1997) Audiology and Neuro-Otology , vol.2 , Issue.1-2 , pp. 12-24
    • Kiernan, A.E.1    Fekete, D.M.2
  • 15
    • 0032867726 scopus 로고    scopus 로고
    • Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors
    • DOI 10.1016/S0378-5955(99)00045-3, PII S0378595599000453
    • Derby ML, Sena-Esteves M, Breakefield XO, Corey DP. Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors. Hear Res 1999; 134: 1-8. (Pubitemid 29354511)
    • (1999) Hearing Research , vol.134 , Issue.1-2 , pp. 1-8
    • Derby, M.L.1    Sena-Esteves, M.2    Breakefield, X.O.3    Corey, D.P.4
  • 16
    • 0033022208 scopus 로고    scopus 로고
    • Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors
    • Holt JR, John DC, Wang S, Chen ZY, Dunn RI, Marban E et al. Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors. J Neurophysiol 1999; 81: 1881-1888. (Pubitemid 29262519)
    • (1999) Journal of Neurophysiology , vol.81 , Issue.4 , pp. 1881-1888
    • Holt, J.R.1    Johns, D.C.2    Wang, S.3    Chen, Z.-Y.4    Dunn, R.J.5    Marban, E.6    Corey, D.P.7
  • 18
    • 0033586322 scopus 로고    scopus 로고
    • Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac
    • DOI 10.1089/10430349950018526
    • Yamasoba T, Yagi M, Roessler BJ, Miller JM, Raphael Y. Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac. Hum Gene Ther 1999; 10: 769-774. (Pubitemid 29168161)
    • (1999) Human Gene Therapy , vol.10 , Issue.5 , pp. 769-774
    • Yamasoba, T.1    Yagi, M.2    Roessler, B.J.3    Miller, J.M.4    Raphael, Y.5
  • 19
    • 0034964007 scopus 로고    scopus 로고
    • HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage
    • DOI 10.1006/mthe.2001.0334
    • Chen X, Frisina RD, Bowers WJ, Frisina DR, Federoff HJ. HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatininduced damage. Mol Ther 2001; 3: 958-963. (Pubitemid 32611305)
    • (2001) Molecular Therapy , vol.3 , Issue.6 , pp. 958-963
    • Chen, X.1    Frisina, R.D.2    Bowers, W.J.3    Frisina, D.R.4    Federoff, H.J.5
  • 21
    • 0035668697 scopus 로고    scopus 로고
    • The functional and structural outcome of inner ear gene transfer via the vestibular and cochlear fluids in mice
    • DOI 10.1006/mthe.2001.0490
    • Kawamoto K, Oh SH, Kanzaki S, Brown N, Raphael Y. The functional and structural outcome of inner ear gene transfer via the vestibular and cochlear fluids in mice. Mol Ther 2001; 4: 575-585. (Pubitemid 34026873)
    • (2001) Molecular Therapy , vol.4 , Issue.6 , pp. 575-585
    • Kawamoto, K.1    Oh, S.-H.2    Kanzaki, S.3    Brown, N.4    Raphael, Y.5
  • 22
    • 0035064195 scopus 로고    scopus 로고
    • Gene expression in the mammalian cochlea: A study of multiple vector systems
    • DOI 10.1080/000164801300043307
    • Staecker H, Li D, O'Malley Jr BW, Van de Water TR. Gene expression in the mammalian cochlea: a study of multiple vector systems. Acta Otolarngol 2001; 121: 157-163. (Pubitemid 32328558)
    • (2001) Acta Oto-Laryngologica , vol.121 , Issue.2 , pp. 157-163
    • Staecker, H.1    Li, D.2    O'Malley, B.W.3    Van De Water, T.R.4
  • 23
    • 0034919532 scopus 로고    scopus 로고
    • Cochlear function and transgene expression in the guinea pig cochlea, using adenovirus- and adeno-associated virus-directed gene transfer
    • DOI 10.1089/104303401750148702
    • Luebke AE, Foster PK, Muller CD, Peel AL. Cochlear function and transgene expression in the guinea pig cochlea, using adenovirus- and adeno-associated virus-directed gene transfer. Hum Gene Ther 2001; 12: 773-781. (Pubitemid 32692343)
    • (2001) Human Gene Therapy , vol.12 , Issue.7 , pp. 773-781
    • Luebke, A.E.1    Foster, P.K.2    Muller, C.D.3    Peel, A.L.4
  • 24
    • 0036836933 scopus 로고    scopus 로고
    • Gene transfer into supporting cells of the organ of Corti
    • Ishimoto S, Kawamoto K, Kanzaki S, Raphael Y. Gene transfer into supporting cells of the organ of Corti. Hear Res 2002; 173: 187-197.
    • (2002) Hear Res , vol.173 , pp. 187-197
    • Ishimoto, S.1    Kawamoto, K.2    Kanzaki, S.3    Raphael, Y.4
  • 26
    • 19444370909 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea
    • DOI 10.1016/j.ymthe.2005.02.005, PII S1525001605000584
    • Stone IM, Lurie DI, Kelley MW, Poulsen DJ. Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea. Mol Ther 2005; 11: 843-848. (Pubitemid 40724102)
    • (2005) Molecular Therapy , vol.11 , Issue.6 , pp. 843-848
    • Stone, I.M.1    Lurie, D.I.2    Kelley, M.W.3    Poulsen, D.J.4
  • 27
    • 33746865345 scopus 로고    scopus 로고
    • In Vivo Delivery of Recombinant Viruses to the Fetal Murine Cochlea: Transduction Characteristics and Long-Term Effects on Auditory Function
    • DOI 10.1016/j.ymthe.2006.04.003, PII S1525001606001419
    • Bedrosian JC, Gratton MA, Brigande JV, Tang W, Landau J et al. In vivo delivery of recombinant viruses to the fetal murine cochlea: transduction characteristics and longterm effects on auditory function. Mol Ther 2006; 14: 328-335. (Pubitemid 44184963)
    • (2006) Molecular Therapy , vol.14 , Issue.3 , pp. 328-335
    • Bedrosian, J.C.1    Gratton, M.A.2    Brigande, J.V.3    Tang, W.4    Landau, J.5    Bennett, J.6
  • 29
    • 34447626657 scopus 로고    scopus 로고
    • An in vitro model system to study gene therapy in the human inner ear
    • DOI 10.1038/sj.gt.3302980, PII 3302980
    • Kesser BW, Hashisaki GT, Fletcher K, Eppard H, Holt JR. An in vitro model system to study gene therapy in the human inner ear. Gene Therapy 2007; 14: 1121-1131. (Pubitemid 47086742)
    • (2007) Gene Therapy , vol.14 , Issue.15 , pp. 1121-1131
    • Kesser, B.W.1    Hashisaki, G.T.2    Fletcher, K.3    Eppard, H.4    Holt, J.R.5
  • 30
    • 33845624655 scopus 로고    scopus 로고
    • Coxsackie adenovirus receptor and ανβ3/ανβ5 integrins in adenovirus gene transfer of rat cochlea
    • DOI 10.1038/sj.gt.3302826, PII 3302826
    • Venail F, Wang J, Ruel J, Ballana E, Rebillard G, Eybalin M et al. Coxsackie adenovirus receptor and alpha nu beta3/alpha nu beta5 integrins in adenovirus gene transfer of rat cochlea. Gene Therapy 2007; 14: 30-37. (Pubitemid 44942863)
    • (2007) Gene Therapy , vol.14 , Issue.1 , pp. 30-37
    • Venail, F.1    Wang, J.2    Ruel, J.3    Ballana, E.4    Rebillard, G.5    Eybalin, M.6    Arbones, M.7    Bosch, A.8    Puel, J.-L.9
  • 33
    • 67651204928 scopus 로고    scopus 로고
    • Adenoviral and AAV-Mediated gene transfer to the inner ear: Role of serotype, promoter, and viral load on in vivo and in vitro infection efficiencies
    • Ryan A (ed) Karger: Basel
    • Luebke A, Rova C, Doersten P, Poulsen D. Adenoviral and AAV-Mediated gene transfer to the inner ear: role of serotype, promoter, and viral load on in vivo and in vitro infection efficiencies. In: Ryan A (ed). Gene Therapy of Cochlear Deafness, vol. 66, Karger: Basel, 2009, pp 87-98.
    • (2009) Gene Therapy of Cochlear Deafness , vol.66 , pp. 87-98
    • Luebke, A.1    Rova, C.2    Doersten, P.3    Poulsen, D.4
  • 34
    • 67651236101 scopus 로고    scopus 로고
    • Gene therapy and stem cell transplantation: Strategies for hearing restoration
    • Ryan A (ed) Karger: Basel
    • Kesser B, Lalwani A. Gene therapy and stem cell transplantation: strategies for hearing restoration. In: Ryan A (ed). Gene Therapy of Cochlear Deafness, vol. 66, Karger: Basel, 2009, pp 64-86.
    • (2009) Gene Therapy of Cochlear Deafness , vol.66 , pp. 64-86
    • Kesser, B.1    Lalwani, A.2
  • 35
    • 67651227632 scopus 로고    scopus 로고
    • Gene therapy in the inner ear using adenovirus vectors
    • Ryan A (ed) Karger: Basel
    • Husseman J, Raphael Y. Gene therapy in the inner ear using adenovirus vectors. In: Ryan A (ed). Gene Therapy of Cochlear Deafness, vol. 66, Karger: Basel, 2009, pp 37-51.
    • (2009) Gene Therapy of Cochlear Deafness , vol.66 , pp. 37-51
    • Husseman, J.1    Raphael, Y.2
  • 36
    • 67651236098 scopus 로고    scopus 로고
    • Cellular targeting for cochlear gene therapy
    • Ryan A (ed) Karger: Basel
    • Ryan A, Mullen L, Doherty J. Cellular targeting for cochlear gene therapy. In: Ryan A (ed). Gene Therapy of Cochlear Deafness, vol. 66, Karger: Basel, 2009, pp 99-115.
    • (2009) Gene Therapy of Cochlear Deafness , vol.66 , pp. 99-115
    • Ryan, A.1    Mullen, L.2    Doherty, J.3
  • 38
    • 77951856942 scopus 로고    scopus 로고
    • Guinea pig adenovirus infection does not inhibit cochlear transfection with human adenoviral vectors in a model of hearing loss
    • Hankenson FC, Wathen AB, Eaton KA, Miyazawa T, Swiderski DL, Raphael Y. Guinea pig adenovirus infection does not inhibit cochlear transfection with human adenoviral vectors in a model of hearing loss. Comp Med 2010; 60: 130-135.
    • (2010) Comp Med , vol.60 , pp. 130-135
    • Hankenson, F.C.1    Wathen, A.B.2    Eaton, K.A.3    Miyazawa, T.4    Swiderski, D.L.5    Raphael, Y.6
  • 41
    • 77349089149 scopus 로고    scopus 로고
    • Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue
    • Taura A, Taura K, Choung YH, Masuda M, Pak K, Chavez E et al. Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. Neuroscience 2010; 66: 1185-1193.
    • (2010) Neuroscience , vol.66 , pp. 1185-1193
    • Taura, A.1    Taura, K.2    Choung, Y.H.3    Masuda, M.4    Pak, K.5    Chavez, E.6
  • 42
    • 0034984649 scopus 로고    scopus 로고
    • A modified adenovirus can transfect cochlear hair cells in vivo without compromising cochlear function
    • DOI 10.1038/sj.gt.3301445
    • Luebke AE, Steiger JD, Hodges BL, Amalfitano A. A modified adenovirus can transfect cochlear hair cells in vivo without compromising cochlear function. Gene Therapy 2001; 8: 789-794. (Pubitemid 32509793)
    • (2001) Gene Therapy , vol.8 , Issue.10 , pp. 789-794
    • Luebke, A.E.1    Steiger, J.D.2    Hodges, B.L.3    Amalfitano, A.4
  • 45
    • 40349110922 scopus 로고    scopus 로고
    • Rapid hair cell loss: A mouse model for cochlear lesions
    • Taylor RR, Nevill G, Forge A. Rapid hair cell loss: a mouse model for cochlear lesions. J Assoc Res Otolaryngol 2008; 9: 44-64.
    • (2008) J Assoc Res Otolaryngol , vol.9 , pp. 44-64
    • Taylor, R.R.1    Nevill, G.2    Forge, A.3
  • 46
    • 72249118433 scopus 로고    scopus 로고
    • Supporting cell characteristics in long-deafened aged mouse ears
    • Oesterle EC, Campbell S. Supporting cell characteristics in long-deafened aged mouse ears. J Assoc Res Otolaryngol 2009; 10: 525-544.
    • (2009) J Assoc Res Otolaryngol , vol.10 , pp. 525-544
    • Oesterle, E.C.1    Campbell, S.2
  • 47
    • 0032879483 scopus 로고    scopus 로고
    • Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images
    • DOI 10.1097/00005537-199910000-00021
    • Thorne M, Salt AN, DeMott JE, Henson MM, Henson Jr OW, Gewalt SL. Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images. Laryngoscope 1999; 109: 1661-1668. (Pubitemid 29477235)
    • (1999) Laryngoscope , vol.109 , Issue.10 , pp. 1661-1668
    • Thorne, M.1    Salt, A.N.2    DeMott, J.E.3    Henson, M.M.4    Henson Jr., O.W.5    Gewalt, S.L.6
  • 50
    • 0036806559 scopus 로고    scopus 로고
    • Endocochlear potentials and compound action potential recovery: Functions in the C57BL/6J mouse
    • DOI 10.1016/S0378-5955(02)00552-X, PII S037859550200552X
    • Lang H, Schulte BA, Schmiedt RA. Endocochlear potentials and compound action potential recovery functions in the C57BL/6J mouse. Hear Res 2002; 172: 118-126. (Pubitemid 35299961)
    • (2002) Hearing Research , vol.172 , Issue.1-2 , pp. 118-126
    • Lang, H.1    Schulte, B.A.2    Schmiedt, R.A.3
  • 51
    • 73449091512 scopus 로고    scopus 로고
    • AAV as a gene transfer vector for the treatment of neurological disorders: Novel treatment thoughts for ALS
    • Hester ME, Foust KD, Kaspar RW, Kaspar BK. AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS. Curr Gene Ther 2009; 9: 428-433.
    • (2009) Curr Gene Ther , vol.9 , pp. 428-433
    • Hester, M.E.1    Foust, K.D.2    Kaspar, R.W.3    Kaspar, B.K.4
  • 52
    • 0031906147 scopus 로고    scopus 로고
    • Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
    • Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998; 72: 1438-1445. (Pubitemid 28116931)
    • (1998) Journal of Virology , vol.72 , Issue.2 , pp. 1438-1445
    • Summerford, C.1    Samulski, R.J.2
  • 53
    • 0032589751 scopus 로고    scopus 로고
    • αVβ5 integrin: A co-receptor for adeno-associated virus type 2 infection
    • DOI 10.1038/4768
    • Summerford C, Bartlett JS, Samulski RJ. AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection. Nat Med 1999; 5: 78-82. (Pubitemid 29051002)
    • (1999) Nature Medicine , vol.5 , Issue.1 , pp. 78-82
    • Summerford, C.1    Bartlett, J.S.2    Samulski, R.J.3
  • 54
    • 33748945422 scopus 로고    scopus 로고
    • The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
    • DOI 10.1128/JVI.00878-06
    • Akache B, Grimm D, Pandey K, Yant SR, Xu H, Kay MA. The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. J Virol 2006; 80: 9831-9836. (Pubitemid 44435657)
    • (2006) Journal of Virology , vol.80 , Issue.19 , pp. 9831-9836
    • Akache, B.1    Grimm, D.2    Pandey, K.3    Yant, S.R.4    Xu, H.5    Kay, M.A.6
  • 55
    • 7244243921 scopus 로고    scopus 로고
    • Analysis of the interaction between adeno-associated virus and heparan sulfate using atomic force microscopy
    • DOI 10.1093/glycob/cwh118
    • Negishi A, Chen J, McCarty DM, Samulski RJ, Liu J, Superfine R. Analysis of the interaction between adeno-associated virus and heparan sulfate using atomic force microscopy. Glycobiology 2004; 14: 969-977. (Pubitemid 39430029)
    • (2004) Glycobiology , vol.14 , Issue.11 , pp. 969-977
    • Negishi, A.1    Chen, J.2    McCarty, D.M.3    Samulski, R.J.4    Liu, J.5    Superfine, R.6
  • 56
    • 0030271580 scopus 로고    scopus 로고
    • The fine structure of spiral ligament cells relates to ion return to the stria and varies with place-frequency
    • DOI 10.1016/0378-5955(96)00106-2
    • Spicer SS, Schulte BA. The fine structure of spiral ligament cells relates to ion return to the stria and varies with place-frequency. Hear Res 1996; 100: 80-100. (Pubitemid 26359766)
    • (1996) Hearing Research , vol.100 , Issue.1-2 , pp. 80-100
    • Spicer, S.S.1    Schulte, B.A.2
  • 57
    • 0033610019 scopus 로고    scopus 로고
    • Perspectives: Biomedicine. The benefits of recycling
    • Steel KP. Perspectives: biomedicine. The benefits of recycling. Science 1999; 285: 1363-1364.
    • (1999) Science , vol.285 , pp. 1363-1364
    • Steel, K.P.1
  • 59
    • 77952554436 scopus 로고    scopus 로고
    • Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleae
    • Shibata SB, Cortez SR, Beyer LA, Wiler JA, Di Polo A, Pfingst BE et al. Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleae. Exp Neurol 2010; 223: 464-472.
    • (2010) Exp Neurol , vol.223 , pp. 464-472
    • Shibata, S.B.1    Cortez, S.R.2    Beyer, L.A.3    Wiler, J.A.4    Di Polo, A.5    Pfingst, B.E.6
  • 60
    • 0034766041 scopus 로고    scopus 로고
    • A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors
    • DOI 10.1006/mthe.2001.0462
    • Auricchio A, O'Connor E, Hildinger M, Wilson JM. A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors. Mol Ther 2001; 4: 372-374. (Pubitemid 33040523)
    • (2001) Molecular Therapy , vol.4 , Issue.4 , pp. 372-374
    • Auricchio, A.1    O'Connor, E.2    Hildinger, M.3    Wilson, J.M.4
  • 61
    • 33645455616 scopus 로고    scopus 로고
    • Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noiseinduced hearing loss
    • Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS, Schmiedt RA. Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noiseinduced hearing loss. J Neurosci 2006; 26: 3541-3550.
    • (2006) J Neurosci , vol.26 , pp. 3541-3550
    • Lang, H.1    Schulte, B.A.2    Zhou, D.3    Smythe, N.4    Spicer, S.S.5    Schmiedt, R.A.6
  • 62
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994; 263: 802-805. (Pubitemid 24093206)
    • (1994) Science , vol.263 , Issue.5148 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.