Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice

Gene Therapy

Volumn 21, Issue 1, 2014, Pages 71-80

  Yu, Q ^a,b   Wang, Y ^c   Chang, Q ^b   Wang, J ^b   Gong, S ^a   Li, H ^c   Lin, X ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

cochlea; connexin26; deafness; gene therapy; Gjb2; hearing; scala media

Indexed keywords

CONNEXIN 26; PARVOVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; CELL DEATH; CELL MEMBRANE; COCHLEA DUCT; CONTROLLED STUDY; CORTI ORGAN; EVOKED BRAIN STEM AUDITORY RESPONSE; GAP JUNCTION; INOCULATION; KNOCKOUT MOUSE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPIRAL GANGLION; VIRAL GENE THERAPY; VIRUS EXPRESSION;

EPITONIUM; MUS;

ANIMALS; ANIMALS, NEWBORN; COCHLEAR DUCT; CONNEXINS; DEAFNESS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GAP JUNCTIONS; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN OF CORTI; PROTEIN TRANSPORT;

EID: 84891740321     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2013.59     Document Type: Article

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