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Volumn 142, Issue , 2014, Pages 99-106

Alzheimer's disease: Review of hormone therapy trials and implications for treatment and prevention after menopause

Author keywords

Alzheimer's disease; Estrogen; Hormone therapy; Menopause; Selective estrogen receptor modulator

Indexed keywords

CONJUGATED ESTROGEN; ESTRADIOL; ESTROGEN; PHYTOESTROGEN;

EID: 84899948662     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.05.010     Document Type: Review
Times cited : (129)

References (106)
  • 1
    • 0028222376 scopus 로고
    • Changes of ovarian hormonal function with aging
    • H.L. Judd, and N. Fournet Changes of ovarian hormonal function with aging Experimental Gerontology 29 1994 285 298
    • (1994) Experimental Gerontology , vol.29 , pp. 285-298
    • Judd, H.L.1    Fournet, N.2
  • 2
    • 0034457514 scopus 로고    scopus 로고
    • A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition
    • H.G. Burger, E.C. Dudley, J. Cui, L. Dennerstein, and J.L. Hopper A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition Journal of Clinical Endocrinology and Metabolism 85 2000 2832 2838
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 2832-2838
    • Burger, H.G.1    Dudley, E.C.2    Cui, J.3    Dennerstein, L.4    Hopper, J.L.5
  • 3
    • 84872841524 scopus 로고    scopus 로고
    • Gender, sex steroid hormones, and Alzheimer's disease
    • R.S. Vest, and C.J. Pike Gender, sex steroid hormones, and Alzheimer's disease Hormones and Behavior 63 2013 301 307
    • (2013) Hormones and Behavior , vol.63 , pp. 301-307
    • Vest, R.S.1    Pike, C.J.2
  • 4
    • 0033967348 scopus 로고    scopus 로고
    • Estrogen binding and estrogen receptor characterization (ERα and ERβ) in the cholinergic neurons of the rat basal forebrain
    • P.J. Shughrue, P.J. Scrimo, and I. Merchenthaler Estrogen binding and estrogen receptor characterization (ERα and ERβ) in the cholinergic neurons of the rat basal forebrain Neuroscience 96 2000 41 49
    • (2000) Neuroscience , vol.96 , pp. 41-49
    • Shughrue, P.J.1    Scrimo, P.J.2    Merchenthaler, I.3
  • 5
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β MRNA in the rat central nervous system
    • P.J. Shughrue, M.V. Lane, and I. Merchenthaler Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system Journal of Comparative Neurology 388 1997 507 525
    • (1997) Journal of Comparative Neurology , vol.388 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 12
    • 0028053251 scopus 로고
    • Cognitive deficits of men and women with Alzheimer's disease
    • V.W. Henderson, and J.G. Buckwalter Cognitive deficits of men and women with Alzheimer's disease Neurology 44 1994 90 96
    • (1994) Neurology , vol.44 , pp. 90-96
    • Henderson, V.W.1    Buckwalter, J.G.2
  • 13
    • 0028872284 scopus 로고
    • Gender differences in language of AD patients: A longitudinal study
    • D.N. Ripich, S.A. Petrill, P.J. Whitehouse, and E.W. Ziol Gender differences in language of AD patients: a longitudinal study Neurology 45 1995 299 302
    • (1995) Neurology , vol.45 , pp. 299-302
    • Ripich, D.N.1    Petrill, S.A.2    Whitehouse, P.J.3    Ziol, E.W.4
  • 14
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P301L tau transgenic mice induced by A42 fibrils
    • J. Götz, F. Chen, J. van Dorpe, and R.M. Nitsch Formation of neurofibrillary tangles in P301L tau transgenic mice induced by A42 fibrils Science 293 2001 1491 1495
    • (2001) Science , vol.293 , pp. 1491-1495
    • Götz, J.1    Chen, F.2    Van Dorpe, J.3    Nitsch, R.M.4
  • 22
    • 0037343967 scopus 로고    scopus 로고
    • Apolipoprotein e enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals
    • K.H. Gylys, J.A. Fein, A.M. Tan, and G.M. Cole Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals Journal of Neurochemistry 84 2003 1442 1451
    • (2003) Journal of Neurochemistry , vol.84 , pp. 1442-1451
    • Gylys, K.H.1    Fein, J.A.2    Tan, A.M.3    Cole, G.M.4
  • 24
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiological Reviews 81 2001 741 746
    • (2001) Physiological Reviews , vol.81 , pp. 741-746
    • Selkoe, D.J.1
  • 25
    • 0020686674 scopus 로고
    • Alzheimer's disease: A disorder of cortical cholinergic innervation
    • J.T. Coyle, D.L. Price, and M.R. DeLong Alzheimer's disease: a disorder of cortical cholinergic innervation Science 219 1983 1184 1190
    • (1983) Science , vol.219 , pp. 1184-1190
    • Coyle, J.T.1    Price, D.L.2    Delong, M.R.3
  • 27
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • J.A. Schneider, Z. Arvanitakis, W. Bang, and D.A. Bennett Mixed brain pathologies account for most dementia cases in community-dwelling older persons Neurology 69 2007 2197 2204
    • (2007) Neurology , vol.69 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3    Bennett, D.A.4
  • 30
    • 77956173214 scopus 로고    scopus 로고
    • Influence of different estrogens on neuroplasticity and cognition in the hippocampus
    • C.K. Barha, and L.A. Galea Influence of different estrogens on neuroplasticity and cognition in the hippocampus Biochimica et Biophysica Acta 1800 2010 1056 1067
    • (2010) Biochimica et Biophysica Acta , vol.1800 , pp. 1056-1067
    • Barha, C.K.1    Galea, L.A.2
  • 33
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
    • Y. Goodman, A.J. Bruce, B. Cheng, and M.P. Mattson Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons Journal of Neurochemistry 66 1996 1836 1844
    • (1996) Journal of Neurochemistry , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 34
    • 0032997908 scopus 로고    scopus 로고
    • L expression and β-amyloid-induced apoptosis: Relevance to Alzheimer's disease
    • L expression and β-amyloid-induced apoptosis: relevance to Alzheimer's disease Journal of Neurochemistry 72 1999 1552 1563
    • (1999) Journal of Neurochemistry , vol.72 , pp. 1552-1563
    • Pike, C.J.1
  • 35
    • 0025833161 scopus 로고
    • Organotypic culture of the developing cerebral cortex and hypothalamus: Relevance to sexual differentiation
    • C.D. Toran-Allerand Organotypic culture of the developing cerebral cortex and hypothalamus: relevance to sexual differentiation Psychoneuroendocrinology 16 1991 7 24
    • (1991) Psychoneuroendocrinology , vol.16 , pp. 7-24
    • Toran-Allerand, C.D.1
  • 36
    • 84858702953 scopus 로고    scopus 로고
    • The ageing cortical synapse: Hallmarks and implications for cognitive decline
    • J.H. Morrison, and M.G. Baxter The ageing cortical synapse: hallmarks and implications for cognitive decline Nature Reviews Neuroscience 13 2012 240 250
    • (2012) Nature Reviews Neuroscience , vol.13 , pp. 240-250
    • Morrison, J.H.1    Baxter, M.G.2
  • 38
    • 0028086440 scopus 로고
    • Estrogen replacement therapy in older women: Comparisons between Alzheimer's disease cases and nondemented control subjects
    • V.W. Henderson, A. Paganini-Hill, C.K. Emanuel, M.E. Dunn, and J.G. Buckwalter Estrogen replacement therapy in older women: comparisons between Alzheimer's disease cases and nondemented control subjects Archives of Neurology 51 1994 896 900
    • (1994) Archives of Neurology , vol.51 , pp. 896-900
    • Henderson, V.W.1    Paganini-Hill, A.2    Emanuel, C.K.3    Dunn, M.E.4    Buckwalter, J.G.5
  • 39
    • 0030152121 scopus 로고    scopus 로고
    • Cognitive skills associated with estrogen replacement in women with Alzheimer's disease
    • V.W. Henderson, L. Watt, and J.G. Buckwalter Cognitive skills associated with estrogen replacement in women with Alzheimer's disease Psychoneuroendocrinology 21 1996 421 430
    • (1996) Psychoneuroendocrinology , vol.21 , pp. 421-430
    • Henderson, V.W.1    Watt, L.2    Buckwalter, J.G.3
  • 40
    • 0030837745 scopus 로고    scopus 로고
    • The Alzheimer's disease assessment scale: Patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials
    • P.M. Doraiswamy, F. Bieber, L. Kaiser, K.R. Krishnan, J. Reuning-Scherer, and B. Gulanski The Alzheimer's disease assessment scale: patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials Neurology 48 1997 1511 1517
    • (1997) Neurology , vol.48 , pp. 1511-1517
    • Doraiswamy, P.M.1    Bieber, F.2    Kaiser, L.3    Krishnan, K.R.4    Reuning-Scherer, J.5    Gulanski, B.6
  • 41
    • 0029886801 scopus 로고    scopus 로고
    • Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease
    • L.S. Schneider, M.R. Farlow, V.W. Henderson, and J.M. Pogoda Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease Neurology 46 1996 1580 1584
    • (1996) Neurology , vol.46 , pp. 1580-1584
    • Schneider, L.S.1    Farlow, M.R.2    Henderson, V.W.3    Pogoda, J.M.4
  • 44
    • 0028087659 scopus 로고
    • Evaluation of estrogen treatment in female patients with dementia of the Alzheimer type
    • T. Ohkura, K. Isse, K. Akazawa, M. Hamamoto, Y. Yaoi, and N. Hagino Evaluation of estrogen treatment in female patients with dementia of the Alzheimer type Endocrine Journal 41 1994 361 371
    • (1994) Endocrine Journal , vol.41 , pp. 361-371
    • Ohkura, T.1    Isse, K.2    Akazawa, K.3    Hamamoto, M.4    Yaoi, Y.5    Hagino, N.6
  • 45
    • 0033003028 scopus 로고    scopus 로고
    • Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: Results of a placebo-controlled, double-blind, pilot study
    • S. Asthana, S. Craft, L.D. Baker, M.A. Raskind, R.S. Birnbaum, C.P. Lofgreen, R.C. Veith, and S.R. Plymate Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: results of a placebo-controlled, double-blind, pilot study Psychoneuroendocrinology 24 1999 657 677
    • (1999) Psychoneuroendocrinology , vol.24 , pp. 657-677
    • Asthana, S.1    Craft, S.2    Baker, L.D.3    Raskind, M.A.4    Birnbaum, R.S.5    Lofgreen, C.P.6    Veith, R.C.7    Plymate, S.R.8
  • 47
    • 80053482654 scopus 로고    scopus 로고
    • Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: Results of a randomized controlled trial
    • W. Wharton, L.D. Baker, C.E. Gleason, M. Dowling, J.H. Barnet, S. Johnson, C. Carlsson, S. Craft, and S. Asthana Short-term hormone therapy with transdermal estradiol improves cognition for postmenopausal women with Alzheimer's disease: results of a randomized controlled trial Journal of Alzheimer's Disease 26 2011 495 505
    • (2011) Journal of Alzheimer's Disease , vol.26 , pp. 495-505
    • Wharton, W.1    Baker, L.D.2    Gleason, C.E.3    Dowling, M.4    Barnet, J.H.5    Johnson, S.6    Carlsson, C.7    Craft, S.8    Asthana, S.9
  • 49
    • 0037435541 scopus 로고    scopus 로고
    • No additional benefit of HRT on response to rivastigmine in menopausal women with AD
    • A.S. Rigaud, G. Andre, B. Vellas, J. Touchon, and J.J. Pere No additional benefit of HRT on response to rivastigmine in menopausal women with AD Neurology 60 2003 148 149
    • (2003) Neurology , vol.60 , pp. 148-149
    • Rigaud, A.S.1    Andre, G.2    Vellas, B.3    Touchon, J.4    Pere, J.J.5
  • 53
    • 74349086281 scopus 로고    scopus 로고
    • Effects of hormone therapy on depressive symptoms and cognitive functions in women with Alzheimer disease: A 12 month randomized, double-blind, placebo-controlled study of low-dose estradiol and norethisterone
    • A. Valen-Sendstad, K. Engedal, B. Stray-Pedersen, C. Strobel, L. Barnett, N. Meyer, and M. Nurminemi Effects of hormone therapy on depressive symptoms and cognitive functions in women with Alzheimer disease: a 12 month randomized, double-blind, placebo-controlled study of low-dose estradiol and norethisterone American Journal of Geriatric Psychiatry 18 2010 11 20
    • (2010) American Journal of Geriatric Psychiatry , vol.18 , pp. 11-20
    • Valen-Sendstad, A.1    Engedal, K.2    Stray-Pedersen, B.3    Strobel, C.4    Barnett, L.5    Meyer, N.6    Nurminemi, M.7
  • 54
    • 0000366424 scopus 로고
    • An evaluation of psychologic effects of sex hormone administration in aged women. I. Results of therapy after six months
    • B.M. Caldwell, and R.I. Watson An evaluation of psychologic effects of sex hormone administration in aged women. I. Results of therapy after six months Journal of Gerontology 7 1952 228 244
    • (1952) Journal of Gerontology , vol.7 , pp. 228-244
    • Caldwell, B.M.1    Watson, R.I.2
  • 56
    • 0030942683 scopus 로고    scopus 로고
    • The role of estrogen in the treatment of Alzheimer's disease
    • S.J. Birge The role of estrogen in the treatment of Alzheimer's disease Neurology 48 Suppl. 7 1997 S36 S41
    • (1997) Neurology , vol.48 , Issue.SUPPL. 7
    • Birge, S.J.1
  • 58
    • 84864311250 scopus 로고    scopus 로고
    • Estrogen regulation of mitochondrial bioenergetics: Implications for prevention of Alzheimer's disease
    • J. Yao, and R.D. Brinton Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease Advances in Pharmacology 64 2012 327 371
    • (2012) Advances in Pharmacology , vol.64 , pp. 327-371
    • Yao, J.1    Brinton, R.D.2
  • 59
  • 61
    • 84863505421 scopus 로고    scopus 로고
    • Reconciling subjective memory complaints with objective memory performance in the menopausal transition
    • M.T. Weber, M. Mapstone, J. Staskiewicz, and P.M. Maki Reconciling subjective memory complaints with objective memory performance in the menopausal transition Menopause 19 2012 735 741
    • (2012) Menopause , vol.19 , pp. 735-741
    • Weber, M.T.1    Mapstone, M.2    Staskiewicz, J.3    Maki, P.M.4
  • 62
    • 0036792775 scopus 로고    scopus 로고
    • Dementia and Alzheimer disease incidence rates do not vary by sex in Rochester, Minn
    • S.D. Edland, W.A. Rocca, R.C. Petersen, R.H. Cha, and E. Kokmen Dementia and Alzheimer disease incidence rates do not vary by sex in Rochester, Minn Archives of Neurology 59 2002 1589 1593
    • (2002) Archives of Neurology , vol.59 , pp. 1589-1593
    • Edland, S.D.1    Rocca, W.A.2    Petersen, R.C.3    Cha, R.H.4    Kokmen, E.5
  • 64
    • 0029844969 scopus 로고    scopus 로고
    • Estrogen replacement therapy and risk of Alzheimer's disease
    • A. Paganini-Hill, and V.W. Henderson Estrogen replacement therapy and risk of Alzheimer's disease Archives of Internal Medicine 156 1996 2213 2217
    • (1996) Archives of Internal Medicine , vol.156 , pp. 2213-2217
    • Paganini-Hill, A.1    Henderson, V.W.2
  • 68
    • 34948829010 scopus 로고    scopus 로고
    • Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause
    • W.A. Rocca, J.H. Bower, J.E. Ahlskog, B.R. Grossardt, M. de Andrade, and L.J. Melton III Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause Neurology 69 2007 1074 1083
    • (2007) Neurology , vol.69 , pp. 1074-1083
    • Rocca, W.A.1    Bower, J.H.2    Ahlskog, J.E.3    Grossardt, B.R.4    De Andrade, M.5    Melton III, L.J.6
  • 71
    • 33645980353 scopus 로고    scopus 로고
    • Cognitive function across the life course and the menopausal transition in a British birth cohort
    • H.S. Kok, D. Kuh, R. Cooper, Y.T. van der Schouw, D.E. Grobbee, W.M. E, and M. Richards Cognitive function across the life course and the menopausal transition in a British birth cohort Menopause 13 2006 19 27
    • (2006) Menopause , vol.13 , pp. 19-27
    • Kok, H.S.1    Kuh, D.2    Cooper, R.3    Van Der Schouw, Y.T.4    Grobbee, D.E.5    Richards, M.6
  • 72
    • 34248172932 scopus 로고    scopus 로고
    • Surgical versus natural menopause: Cognitive issues
    • V.W. Henderson, and B.B. Sherwin Surgical versus natural menopause: cognitive issues Menopause 14 2007 572 579
    • (2007) Menopause , vol.14 , pp. 572-579
    • Henderson, V.W.1    Sherwin, B.B.2
  • 75
    • 16844368852 scopus 로고    scopus 로고
    • Effect of raloxifene on the prevention of dementia and cognitive impairment in older women: The Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial
    • K. Yaffe, K. Krueger, S.R. Cummings, T. Blackwell, V.W. Henderson, S. Sarkar, K. Ensrud, and D. Grady Effect of raloxifene on the prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial American Journal of Psychiatry 162 2005 683 690
    • (2005) American Journal of Psychiatry , vol.162 , pp. 683-690
    • Yaffe, K.1    Krueger, K.2    Cummings, S.R.3    Blackwell, T.4    Henderson, V.W.5    Sarkar, S.6    Ensrud, K.7    Grady, D.8
  • 76
    • 0034669062 scopus 로고    scopus 로고
    • The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: A meta-analysis
    • E. Hogervorst, J. Williams, M. Budge, W. Riedel, and J. Jolles The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis Neuroscience 101 2000 485 512
    • (2000) Neuroscience , vol.101 , pp. 485-512
    • Hogervorst, E.1    Williams, J.2    Budge, M.3    Riedel, W.4    Jolles, J.5
  • 80
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • C. Kawas, S. Resnick, A. Morrison, R. Brookmeyer, M. Corrada, A. Zonderman, C. Bacal, D. Donnell Lingle, and E. Metter A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging Neurology 48 1997 1517 1521
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3    Brookmeyer, R.4    Corrada, M.5    Zonderman, A.6    Bacal, C.7    Donnell Lingle, D.8    Metter, E.9
  • 84
    • 33644499808 scopus 로고    scopus 로고
    • Estrogen-containing hormone therapy and Alzheimer's disease risk: Understanding discrepant inferences from observational and experimental research
    • V.W. Henderson Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research Neuroscience 138 2006 1031 1039
    • (2006) Neuroscience , vol.138 , pp. 1031-1039
    • Henderson, V.W.1
  • 85
    • 0034594465 scopus 로고    scopus 로고
    • Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats
    • R.B. Gibbs Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats Neurobiology of Aging 21 2000 107 116
    • (2000) Neurobiology of Aging , vol.21 , pp. 107-116
    • Gibbs, R.B.1
  • 86
    • 0035683871 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on cognitive and brain aging
    • S.M. Resnick, and P.M. Maki Effects of hormone replacement therapy on cognitive and brain aging Annals of the New York Academy of Sciences 949 2001 303 314
    • (2001) Annals of the New York Academy of Sciences , vol.949 , pp. 303-314
    • Resnick, S.M.1    Maki, P.M.2
  • 88
    • 13444256287 scopus 로고    scopus 로고
    • Early postmenopausal hormone replacement therapy may prevent cognitive impairment later in life
    • Y.Z. Bagger, L.B. Tankó, P. Alexandersen, G. Qin, and C. Christiansen Early postmenopausal hormone replacement therapy may prevent cognitive impairment later in life Menopause 12 2005 12 17
    • (2005) Menopause , vol.12 , pp. 12-17
    • Bagger, Y.Z.1    Tankó, L.B.2    Alexandersen, P.3    Qin, G.4    Christiansen, C.5
  • 90
    • 79551493889 scopus 로고    scopus 로고
    • Timing of hormone therapy and dementia: The critical window theory revisited
    • R.A. Whitmer, C.P. Quesenberry, J. Zhou, and K. Yaffe Timing of hormone therapy and dementia: the critical window theory revisited Annals of Neurology 69 2011 163 169
    • (2011) Annals of Neurology , vol.69 , pp. 163-169
    • Whitmer, R.A.1    Quesenberry, C.P.2    Zhou, J.3    Yaffe, K.4
  • 94
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • J. Nilsen, and R.D. Brinton Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling Proceedings of the National Academy of Sciences of the United States of America 100 2003 10506 10511
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 95
    • 33749824242 scopus 로고    scopus 로고
    • Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: Therapeutic implications
    • S. Chen, J. Nilsen, and R.D. Brinton Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implications Endocrinology 147 2006 5303 5313
    • (2006) Endocrinology , vol.147 , pp. 5303-5313
    • Chen, S.1    Nilsen, J.2    Brinton, R.D.3
  • 97
    • 84876059228 scopus 로고    scopus 로고
    • Progestogens used in postmenopausal hormone therapy: Differences in their pharmacological properties, intracellular actions, and clinical effects
    • F.Z. Stanczyk, J.P. Hapgood, S. Winer, and D.R. Mishell Jr. Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects Endocrine Reviews 34 2013 171 208
    • (2013) Endocrine Reviews , vol.34 , pp. 171-208
    • Stanczyk, F.Z.1    Hapgood, J.P.2    Winer, S.3    Mishell Jr., D.R.4
  • 99
    • 38149075863 scopus 로고    scopus 로고
    • Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women
    • R. Karim, H.N. Hodis, F.Z. Stanczyk, R.A. Lobo, and W.J. Mack Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women Journal of Clinical Endocrinology and Metabolism 93 2008 131 138
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 131-138
    • Karim, R.1    Hodis, H.N.2    Stanczyk, F.Z.3    Lobo, R.A.4    Mack, W.J.5
  • 101
    • 34447282249 scopus 로고    scopus 로고
    • Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression
    • T.B. Clarkson Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression Menopause 14 2007 373 384
    • (2007) Menopause , vol.14 , pp. 373-384
    • Clarkson, T.B.1
  • 104
    • 69549133273 scopus 로고    scopus 로고
    • Frontiers proposal. National Institute of Aging "bench to bedside: Estrogen as a case study"
    • Proposal For Estrogen And Cognitive Aging Work Groups
    • S. Asthana, R.D. Brinton, V.W. Henderson, B.S. McEwen, J.H. Morrison, P.J. Schmidt, and Frontiers Proposal for Estrogen and Cognitive Aging Work Groups Frontiers proposal. National Institute of Aging "bench to bedside: estrogen as a case study" Age (Dordrecht, Netherlands) 31 2009 199 210
    • (2009) Age (Dordrecht, Netherlands) , vol.31 , pp. 199-210
    • Asthana, S.1    Brinton, R.D.2    Henderson, V.W.3    McEwen, B.S.4    Morrison, J.H.5    Schmidt, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.