-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
PMID:13332224
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11:298-300; PMID:13332224; http://dx.doi.org/10.1093/geronj/11. 3.298
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
2
-
-
0036591853
-
Protein turnover by the proteasome in aging and disease
-
PMID:12031893
-
Shringarpure R, Davies KJ. Protein turnover by the proteasome in aging and disease. Free Radic Biol Med 2002; 32:1084-9; PMID:12031893; http://dx.doi.org/10.1016/S0891-5849(02)00824-9
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1084-1089
-
-
Shringarpure, R.1
Davies, K.J.2
-
3
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
PMID:12200035
-
Krtolica A, Campisi J. Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 2002; 34:1401-14; PMID:12200035; http://dx.doi.org/10.1016/S1357-2725(02)00053-5
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
4
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
PMID:11089981
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408:239-47; PMID:11089981; http://dx.doi.org/10.1038/ 35041687
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
5
-
-
0037202602
-
Mitochondrial DNA repair and aging
-
PMID:12427535
-
Mandavilli BS, Santos JH, Van Houten B. Mitochondrial DNA repair and aging. Mutat Res 2002; 509:127-51; PMID:12427535; http://dx.doi.org/10.1016/ S0027-5107(02)00220-8
-
(2002)
Mutat Res
, vol.509
, pp. 127-151
-
-
Mandavilli, B.S.1
Santos, J.H.2
Van Houten, B.3
-
6
-
-
0031916984
-
The free radical theory of aging matures
-
PMID:9562038
-
Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78:547-81; PMID:9562038
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
7
-
-
0141790263
-
Invited review: Theories of aging
-
PMID:12970376
-
Weinert BT, Timiras PS. Invited review: Theories of aging. J Appl Physiol (1985) 2003; 95:1706-16; PMID:12970376
-
(1985)
J Appl Physiol
, vol.95
, pp. 1706-1716
-
-
Weinert, B.T.1
Timiras, P.S.2
-
8
-
-
84862884156
-
Mitochondrial quality control: An integrated network of pathways
-
PMID:22410198
-
Fischer F, Hamann A, Osiewacz HD. Mitochondrial quality control: an integrated network of pathways. Trends Biochem Sci 2012; 37:284-92; PMID:22410198; http://dx.doi.org/10.1016/j.tibs.2012.02.004
-
(2012)
Trends Biochem Sci
, vol.37
, pp. 284-292
-
-
Fischer, F.1
Hamann, A.2
Osiewacz, H.D.3
-
9
-
-
77951411789
-
Impossibility of obtaining uninterrupted and unlimited multiplication of the ascomycete Podospora anserina
-
(in English) . PMID:13107134
-
Rizet G. Impossibility of obtaining uninterrupted and unlimited multiplication of the ascomycete Podospora anserina . (in English) . C R Hebd Seances Acad Sci 1953; 237:838-40; PMID:13107134
-
(1953)
C R Hebd Seances Acad Sci
, vol.237
, pp. 838-840
-
-
Rizet, G.1
-
10
-
-
0000912663
-
Podospora anserina
-
King RC, ed. New York: Plenum Press
-
Esser K. Podospora anserina . In: King RC, ed. Handbook of Genetics. New York: Plenum Press, 1974; 531-551.
-
(1974)
Handbook of Genetics
, pp. 531-551
-
-
Esser, K.1
-
11
-
-
0025818937
-
Integrative transformation of the ascomycete Podospora anserina: Identification of the mating-type locus on chromosome VII of electrophoretically separated chromosomes
-
PMID:1367277
-
Osiewacz HD, Skaletz A, Esser K. Integrative transformation of the ascomycete Podospora anserina : identification of the mating-type locus on chromosome VII of electrophoretically separated chromosomes. Appl Microbiol Biotechnol 1991; 35:38-45; PMID:1367277; http://dx.doi.org/10.1007/BF00180633
-
(1991)
Appl Microbiol Biotechnol
, vol.35
, pp. 38-45
-
-
Osiewacz, H.D.1
Skaletz, A.2
Esser, K.3
-
12
-
-
28044460497
-
A two-step protocol for efficient deletion of genes in the filamentous ascomycete Podospora anserina
-
PMID:16160832
-
Hamann A, Krause K, Werner A, Osiewacz HD. A two-step protocol for efficient deletion of genes in the filamentous ascomycete Podospora anserina. Curr Genet 2005; 48:270-5; PMID:16160832; http://dx.doi.org/10.1007/s00294-005- 0018-1
-
(2005)
Curr Genet
, vol.48
, pp. 270-275
-
-
Hamann, A.1
Krause, K.2
Werner, A.3
Osiewacz, H.D.4
-
13
-
-
84878419118
-
Assessing organismal aging in the filamentous fungus Podospora anserina
-
PMID:23296676
-
Osiewacz HD, Hamann A, Zintel S. Assessing organismal aging in the filamentous fungus Podospora anserina. Methods Mol Biol 2013; 965:439-62; PMID:23296676; http://dx.doi.org/10.1007/978-1-62703-239-1-29
-
(2013)
Methods Mol Biol
, vol.965
, pp. 439-462
-
-
Osiewacz, H.D.1
Hamann, A.2
Zintel, S.3
-
14
-
-
0030885350
-
Mitochondrial DNA rearrangements of Podospora anserina are under the control of the nuclear gene grisea
-
PMID:9380708
-
Borghouts C, Kimpel E, Osiewacz HD. Mitochondrial DNA rearrangements of Podospora anserina are under the control of the nuclear gene grisea. Proc Natl Acad Sci U S A 1997; 94:10768-73; PMID:9380708; http://dx.doi.org/10.1073/pnas. 94.20.10768
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10768-10773
-
-
Borghouts, C.1
Kimpel, E.2
Osiewacz, H.D.3
-
15
-
-
67651001697
-
A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: Decrease in mitochondrial DNA repair activity during ageing
-
PMID:19486911
-
Soerensen M, Gredilla R, Müller-Ohldach M, Werner A, Bohr VA, Osiewacz HD, Stevnsner T. A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: decrease in mitochondrial DNA repair activity during ageing. Mech Ageing Dev 2009; 130:487-96; PMID:19486911; http://dx.doi.org/10.1016/j.mad.2009.05.003
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 487-496
-
-
Soerensen, M.1
Gredilla, R.2
Müller-Ohldach, M.3
Werner, A.4
Bohr, V.A.5
Osiewacz, H.D.6
Stevnsner, T.7
-
16
-
-
0022372385
-
Despite mtDNA polymorphism the mobile intron (plDNA) of the COI gene is present in ten different races of Podospora anserina
-
Kück U, Kappelhoff B, Esser K. Despite mtDNA polymorphism the mobile intron (plDNA) of the COI gene is present in ten different races of Podospora anserina. Curr Genet 1985; 10:59-67; http://dx.doi.org/10.1007/BF00418494
-
(1985)
Curr Genet
, vol.10
, pp. 59-67
-
-
Kück, U.1
Kappelhoff, B.2
Esser, K.3
-
17
-
-
0036830418
-
Copper homeostasis and aging in the fungal model system Podospora anserina: Differential expression of PaCtr3 encoding a copper transporter
-
PMID:12200031
-
Borghouts C, Scheckhuber CQ, Stephan O, Osiewacz HD. Copper homeostasis and aging in the fungal model system Podospora anserina : differential expression of PaCtr3 encoding a copper transporter. Int J Biochem Cell Biol 2002; 34:1355-71; PMID:12200031; http://dx.doi.org/10.1016/S1357-2725(02)00078-X
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1355-1371
-
-
Borghouts, C.1
Scheckhuber, C.Q.2
Stephan, O.3
Osiewacz, H.D.4
-
18
-
-
0029855375
-
GRISEA, a putative copper-activated transcription factor from Podospora anserina involved in differentiation and senescence
-
PMID:8804410
-
Osiewacz HD, Nuber U. GRISEA, a putative copper-activated transcription factor from Podospora anserina involved in differentiation and senescence. Mol Gen Genet 1996; 252:115-24; PMID:8804410; http://dx.doi.org/10.1007/BF02173211
-
(1996)
Mol Gen Genet
, vol.252
, pp. 115-124
-
-
Osiewacz, H.D.1
Nuber, U.2
-
19
-
-
0036085483
-
Respiration, copper availability and SOD activity in P. Anserina strains with different lifespan
-
PMID:12075133
-
Borghouts C, Scheckhuber CQ, Werner A, Osiewacz HD. Respiration, copper availability and SOD activity in P. anserina strains with different lifespan. Biogerontology 2002; 3:143-53; PMID:12075133; http://dx.doi.org/10.1023/A: 1015696404723
-
(2002)
Biogerontology
, vol.3
, pp. 143-153
-
-
Borghouts, C.1
Scheckhuber, C.Q.2
Werner, A.3
Osiewacz, H.D.4
-
20
-
-
77953230237
-
Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening
-
PMID:20080171
-
Zintel S, Schwitalla D, Luce K, Hamann A, Osiewacz HD. Increasing mitochondrial superoxide dismutase abundance leads to impairments in protein quality control and ROS scavenging systems and to lifespan shortening. Exp Gerontol 2010; 45:525-32; PMID:20080171; http://dx.doi.org/10.1016/j.exger.2010. 01.006
-
(2010)
Exp Gerontol
, vol.45
, pp. 525-532
-
-
Zintel, S.1
Schwitalla, D.2
Luce, K.3
Hamann, A.4
Osiewacz, H.D.5
-
21
-
-
84055225015
-
PaCATB, a secreted catalase protecting Podospora anserin a against exogenous oxidative stress
-
Albany NY PMID:21865610
-
Zintel S, Bernhardt D, Rogowska-Wrzesinska A, Osiewacz HD. PaCATB, a secreted catalase protecting Podospora anserin a against exogenous oxidative stress. Aging (Albany NY) 2011; 3:768-81; PMID:21865610
-
(2011)
Aging
, vol.3
, pp. 768-781
-
-
Zintel, S.1
Bernhardt, D.2
Rogowska-Wrzesinska, A.3
Osiewacz, H.D.4
-
22
-
-
67650091290
-
Increasing organismal health-span by enhancing mitochondrial protein quality control
-
PMID:19543272
-
Luce K, Osiewacz HD. Increasing organismal health-span by enhancing mitochondrial protein quality control. Nat Cell Biol 2009; 11:852-8; PMID:19543272; http://dx.doi.org/10.1038/ncb1893
-
(2009)
Nat Cell Biol
, vol.11
, pp. 852-858
-
-
Luce, K.1
Osiewacz, H.D.2
-
23
-
-
84861715696
-
Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain
-
PMID:22693589
-
Adam C, Picard M, Déquard-Chablat M, Sellem CH, Hermann-Le Denmat S, Contamine V. Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain. PLoS One 2012; 7:e38138; PMID:22693589; http://dx.doi.org/10.1371/journal.pone.0038138
-
(2012)
PLoS One
, vol.7
-
-
Adam, C.1
Picard, M.2
Déquard-Chablat, M.3
Sellem, C.H.4
Hermann-Le Denmat, S.5
Contamine, V.6
-
24
-
-
84879151902
-
Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain
-
PMID:23360988
-
Fischer F, Weil A, Hamann A, Osiewacz HD. Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain. Nat Commun 2013; 4:1397; PMID:23360988; http://dx.doi.org/10.1038/ncomms2397
-
(2013)
Nat Commun
, vol.4
, pp. 1397
-
-
Fischer, F.1
Weil, A.2
Hamann, A.3
Osiewacz, H.D.4
-
25
-
-
84055190025
-
Unmasking a temperature-dependent effect of the P. Anserina i-AAA protease on aging and development
-
PMID:22134244
-
Weil A, Luce K, Dröse S, Wittig I, Brandt U, Osiewacz HD. Unmasking a temperature-dependent effect of the P. anserina i-AAA protease on aging and development. Cell Cycle 2011; 10:4280-90; PMID:22134244; http://dx.doi.org/10. 4161/cc.10.24.18560
-
(2011)
Cell Cycle
, vol.10
, pp. 4280-4290
-
-
Weil, A.1
Luce, K.2
Dröse, S.3
Wittig, I.4
Brandt, U.5
Osiewacz, H.D.6
-
26
-
-
34547656326
-
Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina
-
PMID:17627766
-
Hamann A, Brust D, Osiewacz HD. Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina. Mol Microbiol 2007; 65:948-58; PMID:17627766; http://dx.doi.org/10.1111/j.1365-2958. 2007.05839.x
-
(2007)
Mol Microbiol
, vol.65
, pp. 948-958
-
-
Hamann, A.1
Brust, D.2
Osiewacz, H.D.3
-
27
-
-
78349264668
-
Cyclophilin D links programmed cell death and organismal aging in Podospora anserina
-
PMID:20626725
-
Brust D, Daum B, Breunig C, Hamann A, Kühlbrandt W, Osiewacz HD. Cyclophilin D links programmed cell death and organismal aging in Podospora anserina. Aging Cell 2010; 9:761-75; PMID:20626725; http://dx.doi.org/10.1111/j. 1474-9726.2010.00609.x
-
(2010)
Aging Cell
, vol.9
, pp. 761-775
-
-
Brust, D.1
Daum, B.2
Breunig, C.3
Hamann, A.4
Kühlbrandt, W.5
Osiewacz, H.D.6
-
28
-
-
77953230037
-
Deletion of PaAif2 and PaAmid2, two genes encoding mitochondrial AIF-like oxidoreductases of Podospora anserina, leads to increased stress tolerance and lifespan extension
-
PMID:20306265
-
Brust D, Hamann A, Osiewacz HD. Deletion of PaAif2 and PaAmid2, two genes encoding mitochondrial AIF-like oxidoreductases of Podospora anserina, leads to increased stress tolerance and lifespan extension. Curr Genet 2010; 56:225-35; PMID:20306265; http://dx.doi.org/10.1007/s00294-010-0295-1
-
(2010)
Curr Genet
, vol.56
, pp. 225-235
-
-
Brust, D.1
Hamann, A.2
Osiewacz, H.D.3
-
29
-
-
84864061186
-
Deceleration of fusion-fission cycles improves mitochondrial quality control during aging
-
PMID:22761564
-
Figge MT, Reichert AS, Meyer-Hermann M, Osiewacz HD. Deceleration of fusion-fission cycles improves mitochondrial quality control during aging. PLoS Comput Biol 2012; 8:e1002576; PMID:22761564; http://dx.doi.org/10.1371/journal. pcbi.1002576
-
(2012)
PLoS Comput Biol
, vol.8
-
-
Figge, M.T.1
Reichert, A.S.2
Meyer-Hermann, M.3
Osiewacz, H.D.4
-
30
-
-
84874996381
-
Quality control of mitochondria during aging: Is there a good and a bad side of mitochondrial dynamics?
-
PMID:23359437
-
Figge MT, Osiewacz HD, Reichert AS. Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics? Bioessays 2013; 35:314-22; PMID:23359437; http://dx.doi.org/10.1002/bies. 201200125
-
(2013)
Bioessays
, vol.35
, pp. 314-322
-
-
Figge, M.T.1
Osiewacz, H.D.2
Reichert, A.S.3
-
31
-
-
33845876643
-
Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models
-
PMID:17173038
-
Scheckhuber CQ, Erjavec N, Tinazli A, Hamann A, Nyström T, Osiewacz HD. Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models. Nat Cell Biol 2007; 9:99-105; PMID:17173038; http://dx.doi.org/10.1038/ncb1524
-
(2007)
Nat Cell Biol
, vol.9
, pp. 99-105
-
-
Scheckhuber, C.Q.1
Erjavec, N.2
Tinazli, A.3
Hamann, A.4
Nyström, T.5
Osiewacz, H.D.6
-
32
-
-
33747877758
-
Mitochondrial free radical generation and lifespan control in the fungal aging model Podospora anserina
-
PMID:16530367
-
Gredilla R, Grief J, Osiewacz HD. Mitochondrial free radical generation and lifespan control in the fungal aging model Podospora anserina. Exp Gerontol 2006; 41:439-47; PMID:16530367; http://dx.doi.org/10.1016/j.exger.2006.01.010
-
(2006)
Exp Gerontol
, vol.41
, pp. 439-447
-
-
Gredilla, R.1
Grief, J.2
Osiewacz, H.D.3
-
33
-
-
0037242201
-
Autophagy is induced during cell death by incompatibility and is essential for differentiation in the filamentous fungus Podospora anserina
-
PMID:12519185
-
Pinan-Lucarré B, Paoletti M, Dementhon K, Coulary-Salin B, Clavé C. Autophagy is induced during cell death by incompatibility and is essential for differentiation in the filamentous fungus Podospora anserina. Mol Microbiol 2003; 47:321-33; PMID:12519185; http://dx.doi.org/10.1046/j.1365- 2958.2003.03208.x
-
(2003)
Mol Microbiol
, vol.47
, pp. 321-333
-
-
Pinan-Lucarré, B.1
Paoletti, M.2
Dementhon, K.3
Coulary-Salin, B.4
Clavé, C.5
-
34
-
-
27744467466
-
Accelerated cell death in Podospora autophagy mutants
-
PMID:16278443
-
Pinan-Lucarré B, Balguerie A, Clavé C. Accelerated cell death in Podospora autophagy mutants. Eukaryot Cell 2005; 4:1765-74; PMID:16278443; http://dx.doi.org/10.1128/EC.4.11.1765-1774.2005
-
(2005)
Eukaryot Cell
, vol.4
, pp. 1765-1774
-
-
Pinan-Lucarré, B.1
Balguerie, A.2
Clavé, C.3
-
35
-
-
33846461226
-
Cell death by incompatibility in the fungus Podospora
-
PMID:17204431
-
Pinan-Lucarré B, Paoletti M, Clavé C. Cell death by incompatibility in the fungus Podospora. Semin Cancer Biol 2007; 17:101-11; PMID:17204431; http://dx.doi.org/10.1016/j.semcancer.2006.11.009
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 101-111
-
-
Pinan-Lucarré, B.1
Paoletti, M.2
Clavé, C.3
-
36
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
PMID:8224160
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 1993; 333:169-74; PMID:8224160; http://dx.doi.org/10.1016/0014-5793(93)80398-E
-
(1993)
FEBS Lett
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
37
-
-
0029913505
-
Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole
-
PMID:8901576
-
Scott SV, Hefner-Gravink A, Morano KA, Noda T, Ohsumi Y, Klionsky DJ. Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc Natl Acad Sci U S A 1996; 93:12304-8; PMID:8901576; http://dx.doi.org/10.1073/pnas.93.22.12304
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 12304-12308
-
-
Scott, S.V.1
Hefner-Gravink, A.2
Morano, K.A.3
Noda, T.4
Ohsumi, Y.5
Klionsky, D.J.6
-
38
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
PMID:11099404
-
Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290:1717-21; PMID:11099404; http://dx.doi.org/10. 1126/science.290.5497.1717
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
39
-
-
0037016752
-
Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation
-
PMID:11675395
-
Kim J, Huang WP, Stromhaug PE, Klionsky DJ. Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation. J Biol Chem 2002; 277:763-73; PMID:11675395; http://dx.doi.org/10.1074/jbc.M109134200
-
(2002)
J Biol Chem
, vol.277
, pp. 763-773
-
-
Kim, J.1
Huang, W.P.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
40
-
-
84934444765
-
Amino acid regulation of autophagosome formation
-
PMID:18425444
-
Meijer AJ. Amino acid regulation of autophagosome formation. Methods Mol Biol 2008; 445:89-109; PMID:18425444; http://dx.doi.org/10.1007/978-1-59745-157- 4-5
-
(2008)
Methods Mol Biol
, vol.445
, pp. 89-109
-
-
Meijer, A.J.1
-
41
-
-
84880133714
-
Live-cell imaging of Aspergillus nidulans autophagy: RAB1 dependence, Golgi independence and ER involvement
-
PMID:23722157
-
Pinar M, Pantazopoulou A, Peñalva MA. Live-cell imaging of Aspergillus nidulans autophagy: RAB1 dependence, Golgi independence and ER involvement. Autophagy 2013; 9:1024-43; PMID:23722157; http://dx.doi.org/10. 4161/auto.24483
-
(2013)
Autophagy
, vol.9
, pp. 1024-1043
-
-
Pinar, M.1
Pantazopoulou, A.2
Peñalva, M.A.3
-
42
-
-
57749121573
-
Mitophagy in yeast occurs through a selective mechanism
-
PMID:18818209
-
Kanki T, Klionsky DJ. Mitophagy in yeast occurs through a selective mechanism. J Biol Chem 2008; 283:32386-93; PMID:18818209; http://dx.doi.org/10. 1074/jbc.M802403200
-
(2008)
J Biol Chem
, vol.283
, pp. 32386-32393
-
-
Kanki, T.1
Klionsky, D.J.2
-
43
-
-
73449118235
-
Monitoring mitophagy in yeast: The Om45-GFP processing assay
-
PMID:19806021
-
Kanki T, Kang D, Klionsky DJ. Monitoring mitophagy in yeast: the Om45-GFP processing assay. Autophagy 2009; 5:1186-9; PMID:19806021; http://dx.doi.org/ 10.4161/auto.5.8.9854
-
(2009)
Autophagy
, vol.5
, pp. 1186-1189
-
-
Kanki, T.1
Kang, D.2
Klionsky, D.J.3
-
44
-
-
84867041125
-
Angiogenesis impairment in diabetes: Role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2
-
PMID:23056421
-
Liu H, Yu S, Zhang H, Xu J. Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. PLoS One 2012; 7:e46720; PMID:23056421; http://dx.doi.org/10.1371/journal.pone.0046720
-
(2012)
PLoS One
, vol.7
-
-
Liu, H.1
Yu, S.2
Zhang, H.3
Xu, J.4
-
45
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
PMID:1400575
-
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J Cell Biol 1992; 119:301-11; PMID:1400575; http://dx.doi.org/10.1083/jcb.119. 2.301
-
(1992)
J Cell Biol
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
46
-
-
0032512636
-
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
-
PMID:9461583
-
Noda T, Ohsumi Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem 1998; 273:3963-6; PMID:9461583; http://dx.doi.org/10.1074/jbc.273.7.3963
-
(1998)
J Biol Chem
, vol.273
, pp. 3963-3966
-
-
Noda, T.1
Ohsumi, Y.2
-
47
-
-
4344563878
-
Role and regulation of starvation-induced autophagy in the Drosophila fat body
-
PMID:15296714
-
Scott RC, Schuldiner O, Neufeld TP. Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell 2004; 7:167-78; PMID:15296714; http://dx.doi.org/10.1016/j.devcel.2004.07.009
-
(2004)
Dev Cell
, vol.7
, pp. 167-178
-
-
Scott, R.C.1
Schuldiner, O.2
Neufeld, T.P.3
-
48
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. Elegans
-
PMID:18282106
-
Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 2008; 4:e24; PMID:18282106; http://dx.doi.org/10.1371/journal.pgen. 0040024
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
49
-
-
84883369848
-
Structural basis for phosphorylation-triggered autophagic clearance of Salmonella
-
PMID:23805866
-
Rogov VV, Suzuki H, Fiskin E, Wild P, Kniss A, Rozenknop A, Kato R, Kawasaki M, McEwan DG, Löhr F, et al. Structural basis for phosphorylation-triggered autophagic clearance of Salmonella. Biochem J 2013; 454:459-66; PMID:23805866; http://dx.doi.org/10.1042/BJ20121907
-
(2013)
Biochem J
, vol.454
, pp. 459-466
-
-
Rogov, V.V.1
Suzuki, H.2
Fiskin, E.3
Wild, P.4
Kniss, A.5
Rozenknop, A.6
Kato, R.7
Kawasaki, M.8
McEwan, D.G.9
Löhr, F.10
-
50
-
-
43049138051
-
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
-
PMID:18391941
-
Kraft C, Deplazes A, Sohrmann M, Peter M. Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat Cell Biol 2008; 10:602-10; PMID:18391941; http://dx.doi.org/10.1038/ncb1723
-
(2008)
Nat Cell Biol
, vol.10
, pp. 602-610
-
-
Kraft, C.1
Deplazes, A.2
Sohrmann, M.3
Peter, M.4
-
51
-
-
33845329876
-
The significance of peroxisomes in methanol metabolism in methylotrophic yeast
-
PMID:17023065
-
van der Klei IJ, Yurimoto H, Sakai Y, Veenhuis M. The significance of peroxisomes in methanol metabolism in methylotrophic yeast. Biochim Biophys Acta 2006; 1763:1453-62; PMID:17023065; http://dx.doi.org/10.1016/j.bbamcr.2006.07. 016
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 1453-1462
-
-
Van Der Klei, I.J.1
Yurimoto, H.2
Sakai, Y.3
Veenhuis, M.4
-
52
-
-
33745026738
-
Autophagy and aging: The importance of maintaining "clean" cells
-
PMID:16874025
-
Cuervo AM, Bergamini E, Brunk UT, Dröge W, Ffrench M, Terman A. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 2005; 1:131-40; PMID:16874025; http://dx.doi.org/10.4161/auto.1.3.2017
-
(2005)
Autophagy
, vol.1
, pp. 131-140
-
-
Cuervo, A.M.1
Bergamini, E.2
Brunk, U.T.3
Dröge, W.4
Ffrench, M.5
Terman, A.6
-
53
-
-
57649234905
-
Autophagy genes and ageing
-
PMID:19079287
-
Vellai T. Autophagy genes and ageing. Cell Death Differ 2009; 16:94-102; PMID:19079287; http://dx.doi.org/10.1038/cdd.2008.126
-
(2009)
Cell Death Differ
, vol.16
, pp. 94-102
-
-
Vellai, T.1
-
54
-
-
80052303130
-
Autophagy and aging
-
PMID:21884931
-
Rubinsztein DC, Mariño G, Kroemer G. Autophagy and aging. Cell 2011; 146:682-95; PMID:21884931; http://dx.doi.org/10.1016/j.cell.2011.07.030
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Mariño, G.2
Kroemer, G.3
-
55
-
-
12944308330
-
Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
-
PMID:15680321
-
Levine B. Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. Cell 2005; 120:159-62; PMID:15680321
-
(2005)
Cell
, vol.120
, pp. 159-162
-
-
Levine, B.1
-
56
-
-
34447629523
-
Innate and adaptive immunity through autophagy
-
PMID:17663981
-
Schmid D, Münz C. Innate and adaptive immunity through autophagy. Immunity 2007; 27:11-21; PMID:17663981; http://dx.doi.org/10.1016/j.immuni.2007. 07.004
-
(2007)
Immunity
, vol.27
, pp. 11-21
-
-
Schmid, D.1
Münz, C.2
-
57
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
PMID:18191218
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42; PMID:18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
58
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
PMID:20811354
-
Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12:823-30; PMID:20811354; http://dx.doi.org/10.1038/ncb0910-823
-
(2010)
Nat Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
59
-
-
44649195647
-
Apoptosis pathways in fungal growth, development and ageing
-
PMID:18440231
-
Hamann A, Brust D, Osiewacz HD. Apoptosis pathways in fungal growth, development and ageing. Trends Microbiol 2008; 16:276-83; PMID:18440231; http://dx.doi.org/10.1016/j.tim.2008.03.003
-
(2008)
Trends Microbiol
, vol.16
, pp. 276-283
-
-
Hamann, A.1
Brust, D.2
Osiewacz, H.D.3
-
60
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
PMID:17717517
-
Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007; 8:741-52; PMID:17717517; http://dx.doi.org/10.1038/nrm2239
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
61
-
-
57649149333
-
Nomenclature Committee on Cell Death 2009. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009
-
PMID:18846107
-
Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, Blagosklonny MV, El-Deiry WS, Golstein P, Green DR, et al.; Nomenclature Committee on Cell Death 2009. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009; 16:3-11; PMID:18846107; http://dx.doi.org/10.1038/cdd.2008.150
-
(2009)
Cell Death Differ
, vol.16
, pp. 3-11
-
-
Kroemer, G.1
Galluzzi, L.2
Vandenabeele, P.3
Abrams, J.4
Alnemri, E.S.5
Baehrecke, E.H.6
Blagosklonny, M.V.7
El-Deiry, W.S.8
Golstein, P.9
Green, D.R.10
-
62
-
-
34250798552
-
Involvement of a Magnaporthe grisea serine/threonine kinase gene, MgATG1, in appressorium turgor and pathogenesis
-
PMID:17416896
-
Liu XH, Lu JP, Zhang L, Dong B, Min H, Lin FC. Involvement of a Magnaporthe grisea serine/threonine kinase gene, MgATG1, in appressorium turgor and pathogenesis. Eukaryot Cell 2007; 6:997-1005; PMID:17416896; http://dx.doi.org/10.1128/ EC.00011-07
-
(2007)
Eukaryot Cell
, vol.6
, pp. 997-1005
-
-
Liu, X.H.1
Lu, J.P.2
Zhang, L.3
Dong, B.4
Min, H.5
Lin, F.C.6
-
63
-
-
33747343993
-
Functional analysis of the ATG8 homologue Aoatg8 and role of autophagy in differentiation and germination in Aspergillus oryzae
-
PMID:16896216
-
Kikuma T, Ohneda M, Arioka M, Kitamoto K. Functional analysis of the ATG8 homologue Aoatg8 and role of autophagy in differentiation and germination in Aspergillus oryzae. Eukaryot Cell 2006; 5:1328-36; PMID:16896216; http://dx.doi.org/10.1128/EC.00024-06
-
(2006)
Eukaryot Cell
, vol.5
, pp. 1328-1336
-
-
Kikuma, T.1
Ohneda, M.2
Arioka, M.3
Kitamoto, K.4
-
64
-
-
37549000218
-
Unexpected link between metal ion deficiency and autophagy in Aspergillus fumigatus
-
PMID:17921348
-
Richie DL, Fuller KK, Fortwendel J, Miley MD, McCarthy JW, Feldmesser M, Rhodes JC, Askew DS. Unexpected link between metal ion deficiency and autophagy in Aspergillus fumigatus. Eukaryot Cell 2007; 6:2437-47; PMID:17921348; http://dx.doi.org/10.1128/EC.00224-07
-
(2007)
Eukaryot Cell
, vol.6
, pp. 2437-2447
-
-
Richie, D.L.1
Fuller, K.K.2
Fortwendel, J.3
Miley, M.D.4
McCarthy, J.W.5
Feldmesser, M.6
Rhodes, J.C.7
Askew, D.S.8
-
65
-
-
84872203028
-
Autophagy genes Smatg8 and Smatg4 are required for fruiting-body development, vegetative growth and ascospore germination in the filamentous ascomycete Sordaria macrospora
-
PMID:23064313
-
Voigt O, Pöggeler S. Autophagy genes Smatg8 and Smatg4 are required for fruiting-body development, vegetative growth and ascospore germination in the filamentous ascomycete Sordaria macrospora. Autophagy 2013; 9:33-49; PMID:23064313; http://dx.doi.org/10.4161/auto.22398
-
(2013)
Autophagy
, vol.9
, pp. 33-49
-
-
Voigt, O.1
Pöggeler, S.2
-
66
-
-
67349136020
-
SmATG7 is required for viability in the homothallic ascomycete Sordaria macrospora
-
PMID:19351563
-
Nolting N, Bernhards Y, Pöggeler S. SmATG7 is required for viability in the homothallic ascomycete Sordaria macrospora. Fungal Genet Biol 2009; 46:531-42; PMID:19351563; http://dx.doi.org/10.1016/j.fgb.2009.03.008
-
(2009)
Fungal Genet Biol
, vol.46
, pp. 531-542
-
-
Nolting, N.1
Bernhards, Y.2
Pöggeler, S.3
-
67
-
-
84891634374
-
Autophagic kinases SmVPS34 and SmVPS15 are required for viability in the filamentous ascomycete Sordaria macrospora
-
PMID:23953726
-
Voigt O, Herzog B, Jakobshagen A, Pöggeler S. Autophagic kinases SmVPS34 and SmVPS15 are required for viability in the filamentous ascomycete Sordaria macrospora . Microbiol Res 2014; 169:128-38; PMID:23953726; http://dx.doi.org/10.1016/j.micres.2013.07.012
-
(2014)
Microbiol Res
, vol.169
, pp. 128-138
-
-
Voigt, O.1
Herzog, B.2
Jakobshagen, A.3
Pöggeler, S.4
-
68
-
-
57649227755
-
Autophagy in filamentous fungi
-
PMID:19010432
-
Pollack JK, Harris SD, Marten MR. Autophagy in filamentous fungi. Fungal Genet Biol 2009; 46:1-8; PMID:19010432; http://dx.doi.org/10.1016/j.fgb.2008.10. 010
-
(2009)
Fungal Genet Biol
, vol.46
, pp. 1-8
-
-
Pollack, J.K.1
Harris, S.D.2
Marten, M.R.3
-
69
-
-
78049393407
-
Mitochondrial protein quality control systems in aging and disease
-
Tavernarakis N, ed. New York: Springer Science+Buisiness Media, LLC Landes Bioscience
-
Luce K, Weil AC, Osiewacz HD. Mitochondrial protein quality control systems in aging and disease. In: Tavernarakis N, ed. Protein metabolism and homeostasis in aging. New York: Springer Science+Buisiness Media, LLC Landes Bioscience, 2010; 108-125
-
(2010)
Protein Metabolism and Homeostasis in Aging
, pp. 108-125
-
-
Luce, K.1
Weil, A.C.2
Osiewacz, H.D.3
-
70
-
-
84883460271
-
Mitochondrial quality control: Impact on aging and life span - A mini-review
-
PMID:23615432
-
Osiewacz HD, Bernhardt D. Mitochondrial quality control: impact on aging and life span - a mini-review. Gerontology 2013; 59:413-20; PMID:23615432; http://dx.doi.org/10.1159/000348662
-
(2013)
Gerontology
, vol.59
, pp. 413-420
-
-
Osiewacz, H.D.1
Bernhardt, D.2
-
71
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. Elegans
-
PMID:12958363
-
Meléndez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 2003; 301:1387-91; PMID:12958363; http://dx.doi.org/10.1126/science.1087782
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Meléndez, A.1
Tallóczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
72
-
-
33947401070
-
Autophagy regulates ageing in C. Elegans
-
PMID:17204841
-
Hars ES, Qi H, Ryazanov AG, Jin S, Cai L, Hu C, Liu LF. Autophagy regulates ageing in C. elegans. Autophagy 2007; 3:93-5; PMID:17204841
-
(2007)
Autophagy
, vol.3
, pp. 93-95
-
-
Hars, E.S.1
Qi, H.2
Ryazanov, A.G.3
Jin, S.4
Cai, L.5
Hu, C.6
Liu, L.F.7
-
73
-
-
35848937781
-
Autophagy is required for dietary restriction-mediated life span extension in C. Elegans
-
PMID:17912023
-
Jia K, Levine B. Autophagy is required for dietary restriction-mediated life span extension in C. elegans. Autophagy 2007; 3:597-9; PMID:17912023
-
(2007)
Autophagy
, vol.3
, pp. 597-599
-
-
Jia, K.1
Levine, B.2
-
74
-
-
53549122987
-
The effects of p53 on whole organism longevity are mediated by autophagy
-
PMID:18728385
-
Tavernarakis N, Pasparaki A, Tasdemir E, Maiuri MC, Kroemer G. The effects of p53 on whole organism longevity are mediated by autophagy. Autophagy 2008; 4:870-3; PMID:18728385
-
(2008)
Autophagy
, vol.4
, pp. 870-873
-
-
Tavernarakis, N.1
Pasparaki, A.2
Tasdemir, E.3
Maiuri, M.C.4
Kroemer, G.5
-
75
-
-
41449102024
-
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans
-
PMID:18219227
-
Tóth ML, Sigmond T, Borsos E, Barna J, Erdélyi P, Takács-Vellai K, Orosz L, Kovács AL, Csikós G, Sass M, et al. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy 2008; 4:330-8; PMID:18219227
-
(2008)
Autophagy
, vol.4
, pp. 330-338
-
-
Tóth, M.L.1
Sigmond, T.2
Borsos, E.3
Barna, J.4
Erdélyi, P.5
Takács-Vellai, K.6
Orosz, L.7
Kovács, A.L.8
Csikós, G.9
Sass, M.10
-
76
-
-
0031595780
-
IkappaB is a substrate for a selective pathway of lysosomal proteolysis
-
PMID:9693362
-
Cuervo AM, Hu W, Lim B, Dice JF. IkappaB is a substrate for a selective pathway of lysosomal proteolysis. Mol Biol Cell 1998; 9:1995-2010; PMID:9693362; http://dx.doi.org/10.1091/mbc.9.8.1995
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1995-2010
-
-
Cuervo, A.M.1
Hu, W.2
Lim, B.3
Dice, J.F.4
-
77
-
-
33751103909
-
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome
-
PMID:17082767
-
De Domenico I, Vaughn MB, Li L, Bagley D, Musci G, Ward DM, Kaplan J. Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. EMBO J 2006; 25:5396-404; PMID:17082767; http://dx.doi.org/10.1038/sj.emboj.7601409
-
(2006)
EMBO J
, vol.25
, pp. 5396-5404
-
-
De Domenico, I.1
Vaughn, M.B.2
Li, L.3
Bagley, D.4
Musci, G.5
Ward, D.M.6
Kaplan, J.7
-
78
-
-
33748417446
-
Release of iron from ferritin requires lysosomal activity
-
PMID:16611735
-
Kidane TZ, Sauble E, Linder MC. Release of iron from ferritin requires lysosomal activity. Am J Physiol Cell Physiol 2006; 291:C445-55; PMID:16611735; http://dx.doi.org/10.1152/ajpcell.00505.2005
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Kidane, T.Z.1
Sauble, E.2
Linder, M.C.3
-
79
-
-
0041589248
-
Alpha-Synuclein is degraded by both autophagy and the proteasome
-
PMID:12719433
-
Webb JL, Ravikumar B, Atkins J, Skepper JN, Rubinsztein DC. Alpha-Synuclein is degraded by both autophagy and the proteasome. J Biol Chem 2003; 278:25009-13; PMID:12719433; http://dx.doi.org/10.1074/jbc.M300227200
-
(2003)
J Biol Chem
, vol.278
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
80
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
PMID:20959619
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 2010; 90:1383-435; PMID:20959619; http://dx.doi.org/10.1152/physrev.00030. 2009
-
(2010)
Physiol Rev
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
-
81
-
-
84883451249
-
Selective autophagy: Talking with the UPS
-
PMID:23709310
-
Park C, Cuervo AM. Selective autophagy: talking with the UPS. Cell Biochem Biophys 2013; 67:3-13; PMID:23709310; http://dx.doi.org/10.1007/s12013- 013-9623-7
-
(2013)
Cell Biochem Biophys
, vol.67
, pp. 3-13
-
-
Park, C.1
Cuervo, A.M.2
-
82
-
-
69449090071
-
A novel link between autophagy and the ubiquitin-proteasome system
-
PMID:19458478
-
Korolchuk VI, Menzies FM, Rubinsztein DC. A novel link between autophagy and the ubiquitin-proteasome system. Autophagy 2009; 5:862-3; PMID:19458478
-
(2009)
Autophagy
, vol.5
, pp. 862-863
-
-
Korolchuk, V.I.1
Menzies, F.M.2
Rubinsztein, D.C.3
-
83
-
-
77950487987
-
Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
-
PMID:20040365
-
Korolchuk VI, Menzies FM, Rubinsztein DC. Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems. FEBS Lett 2010; 584:1393-8; PMID:20040365; http://dx.doi.org/10.1016/j.febslet.2009.12.047
-
(2010)
FEBS Lett
, vol.584
, pp. 1393-1398
-
-
Korolchuk, V.I.1
Menzies, F.M.2
Rubinsztein, D.C.3
-
84
-
-
10644297368
-
RNA interference toward UMP1 induces proteasome inhibition in Saccharomyces cerevisiae: Evidence for protein oxidation and autophagic cell death
-
PMID:15607905
-
Chen Q, Ding Q, Thorpe J, Dohmen RJ, Keller JN. RNA interference toward UMP1 induces proteasome inhibition in Saccharomyces cerevisiae : evidence for protein oxidation and autophagic cell death. Free Radic Biol Med 2005; 38:226-34; PMID:15607905; http://dx.doi.org/10.1016/j.freeradbiomed.2004.10.019
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 226-234
-
-
Chen, Q.1
Ding, Q.2
Thorpe, J.3
Dohmen, R.J.4
Keller, J.N.5
-
85
-
-
0038493550
-
Characterization of chronic low-level proteasome inhibition on neural homeostasis
-
PMID:12871590
-
Ding Q, Dimayuga E, Martin S, Bruce-Keller AJ, Nukala V, Cuervo AM, Keller JN. Characterization of chronic low-level proteasome inhibition on neural homeostasis. J Neurochem 2003; 86:489-97; PMID:12871590; http://dx.doi.org/10. 1046/j.1471-4159.2003.01885.x
-
(2003)
J Neurochem
, vol.86
, pp. 489-497
-
-
Ding, Q.1
Dimayuga, E.2
Martin, S.3
Bruce-Keller, A.J.4
Nukala, V.5
Cuervo, A.M.6
Keller, J.N.7
-
86
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
PMID:17620365
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171:513-24; PMID:17620365; http://dx.doi.org/10.2353/ajpath.2007.070188
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
87
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
-
PMID:16192271
-
Iwata A, Riley BE, Johnston JA, Kopito RR. HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem 2005; 280:40282-92; PMID:16192271; http://dx.doi.org/10.1074/jbc.M508786200
-
(2005)
J Biol Chem
, vol.280
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
88
-
-
4344583898
-
Involvement of macroautophagy in the dissolution of neuronal inclusions
-
PMID:15325592
-
Rideout HJ, Lang-Rollin I, Stefanis L. Involvement of macroautophagy in the dissolution of neuronal inclusions. Int J Biochem Cell Biol 2004; 36:2551-62; PMID:15325592; http://dx.doi.org/10.1016/j.biocel.2004.05.008
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2551-2562
-
-
Rideout, H.J.1
Lang-Rollin, I.2
Stefanis, L.3
-
89
-
-
51549086469
-
Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement
-
PMID:18640276
-
Pan T, Kondo S, Zhu W, Xie W, Jankovic J, Le W. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. Neurobiol Dis 2008; 32:16-25; PMID:18640276; http://dx.doi.org/10.1016/j.nbd. 2008.06.003
-
(2008)
Neurobiol Dis
, vol.32
, pp. 16-25
-
-
Pan, T.1
Kondo, S.2
Zhu, W.3
Xie, W.4
Jankovic, J.5
Le, W.6
-
90
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
PMID:17568747
-
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007; 447:859-63; PMID:17568747; http://dx.doi.org/10.1038/nature05853
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
DiProspero, N.A.8
Knight, M.A.9
Schuldiner, O.10
-
91
-
-
79952253317
-
Modulation of the glyoxalase system in the aging model Podospora anserina: Effects on growth and lifespan
-
Albany NY PMID:21212464
-
Scheckhuber CQ, Mack SJ, Strobel I, Ricciardi F, Gispert S, Osiewacz HD. Modulation of the glyoxalase system in the aging model Podospora anserina : effects on growth and lifespan. Aging (Albany NY) 2010; 2:969-80; PMID:21212464
-
(2010)
Aging
, vol.2
, pp. 969-980
-
-
Scheckhuber, C.Q.1
Mack, S.J.2
Strobel, I.3
Ricciardi, F.4
Gispert, S.5
Osiewacz, H.D.6
-
92
-
-
84858307371
-
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
-
PMID:22188542
-
Xue M, Rabbani N, Momiji H, Imbasi P, Anwar MM, Kitteringham N, Park BK, Souma T, Moriguchi T, Yamamoto M, et al. Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. Biochem J 2012; 443:213-22; PMID:22188542; http://dx.doi.org/10.1042/BJ20111648
-
(2012)
Biochem J
, vol.443
, pp. 213-222
-
-
Xue, M.1
Rabbani, N.2
Momiji, H.3
Imbasi, P.4
Anwar, M.M.5
Kitteringham, N.6
Park, B.K.7
Souma, T.8
Moriguchi, T.9
Yamamoto, M.10
-
93
-
-
77951227871
-
TOR-dependent control of autophagy: Biting the hand that feeds
-
PMID:20006481
-
Neufeld TP. TOR-dependent control of autophagy: biting the hand that feeds. Curr Opin Cell Biol 2010; 22:157-68; PMID:20006481; http://dx.doi.org/10. 1016/j.ceb.2009.11.005
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 157-168
-
-
Neufeld, T.P.1
-
94
-
-
24744441497
-
Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation
-
PMID:16027116
-
Onodera J, Ohsumi Y. Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem 2005; 280:31582-6; PMID:16027116; http://dx.doi.org/10.1074/jbc.M506736200
-
(2005)
J Biol Chem
, vol.280
, pp. 31582-31586
-
-
Onodera, J.1
Ohsumi, Y.2
-
95
-
-
84883464793
-
Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast
-
PMID:23337777
-
Aris JP, Alvers AL, Ferraiuolo RA, Fishwick LK, Hanvivatpong A, Hu D, Kirlew C, Leonard MT, Losin KJ, Marraffini M, et al. Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast. Exp Gerontol 2013; 48:1107-19; PMID:23337777; http://dx.doi.org/10.1016/j.exger.2013.01.006
-
(2013)
Exp Gerontol
, vol.48
, pp. 1107-1119
-
-
Aris, J.P.1
Alvers, A.L.2
Ferraiuolo, R.A.3
Fishwick, L.K.4
Hanvivatpong, A.5
Hu, D.6
Kirlew, C.7
Leonard, M.T.8
Losin, K.J.9
Marraffini, M.10
-
96
-
-
84899759498
-
Rapamycin slows aging in mice
-
PMID:22587563
-
Wilkinson JE, Burmeister L, Brooks SV, Chan CC, Friedline S, Harrison DE, Hejtmancik JF, Nadon N, Strong R, Wood LK, et al. Rapamycin slows aging in mice. Aging Cell 2012; 8:1371-82; PMID:22587563
-
(2012)
Aging Cell
, vol.8
, pp. 1371-1382
-
-
Wilkinson, J.E.1
Burmeister, L.2
Brooks, S.V.3
Chan, C.C.4
Friedline, S.5
Harrison, D.E.6
Hejtmancik, J.F.7
Nadon, N.8
Strong, R.9
Wood, L.K.10
-
97
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
PMID:19587680
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460:392-5; PMID:19587680
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
-
98
-
-
73049115041
-
Effect of rapamycin on lifespan in Drosophila
-
PMID:20102391
-
Harrison B, Tran TT, Taylor D, Lee SD, Min KJ. Effect of rapamycin on lifespan in Drosophila. Geriatr Gerontol Int 2010; 10:110-2; PMID:20102391; http://dx.doi.org/10.1111/j.1447-0594.2009.00569.x
-
(2010)
Geriatr Gerontol Int
, vol.10
, pp. 110-112
-
-
Harrison, B.1
Tran, T.T.2
Taylor, D.3
Lee, S.D.4
Min, K.J.5
-
99
-
-
69449106873
-
Autophagy is required for extension of yeast chronological life span by rapamycin
-
PMID:19458476
-
Alvers AL, Wood MS, Hu D, Kaywell AC, Dunn WA Jr., Aris JP. Autophagy is required for extension of yeast chronological life span by rapamycin. Autophagy 2009; 5:847-9; PMID:19458476
-
(2009)
Autophagy
, vol.5
, pp. 847-849
-
-
Alvers, A.L.1
Wood, M.S.2
Hu, D.3
Kaywell, A.C.4
Dunn Jr., W.A.5
Aris, J.P.6
-
100
-
-
72649091698
-
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
-
PMID:20074526
-
Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab 2010; 11:35-46; PMID:20074526; http://dx.doi.org/10. 1016/j.cmet.2009.11.010
-
(2010)
Cell Metab
, vol.11
, pp. 35-46
-
-
Bjedov, I.1
Toivonen, J.M.2
Kerr, F.3
Slack, C.4
Jacobson, J.5
Foley, A.6
Partridge, L.7
-
101
-
-
27544500981
-
Growing roles for the mTOR pathway
-
PMID:16226444
-
Sarbassov DD, Ali SM, Sabatini DM. Growing roles for the mTOR pathway. Curr Opin Cell Biol 2005; 17:596-603; PMID:16226444; http://dx.doi.org/10.1016/ j.ceb.2005.09.009
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
102
-
-
84893364380
-
A genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina
-
PMID:24376646
-
Philipp O, Hamann A, Servos J, Werner A, Koch I, Osiewacz HD. A genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina. PLoS One 2013; 8:e83109; PMID:24376646; http://dx.doi.org/10.1371/ journal.pone.0083109
-
(2013)
PLoS One
, vol.8
-
-
Philipp, O.1
Hamann, A.2
Servos, J.3
Werner, A.4
Koch, I.5
Osiewacz, H.D.6
-
103
-
-
0020405985
-
Altered degradation of proteins microinjected into senescent human fibroblasts
-
PMID:7174658
-
Dice JF. Altered degradation of proteins microinjected into senescent human fibroblasts. J Biol Chem 1982; 257:14624-7; PMID:7174658
-
(1982)
J Biol Chem
, vol.257
, pp. 14624-14627
-
-
Dice, J.F.1
-
104
-
-
0034613294
-
Age-related decline in chaperone-mediated autophagy
-
PMID:10806201
-
Cuervo AM, Dice JF. Age-related decline in chaperone-mediated autophagy. J Biol Chem 2000; 275:31505-13; PMID:10806201; http://dx.doi.org/10.1074/jbc. M002102200
-
(2000)
J Biol Chem
, vol.275
, pp. 31505-31513
-
-
Cuervo, A.M.1
Dice, J.F.2
-
105
-
-
33744916798
-
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
-
PMID:16522639
-
Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 2006; 281:14474-85; PMID:16522639; http://dx.doi.org/10.1074/jbc.M600364200
-
(2006)
J Biol Chem
, vol.281
, pp. 14474-14485
-
-
Shibata, M.1
Lu, T.2
Furuya, T.3
Degterev, A.4
Mizushima, N.5
Yoshimori, T.6
MacDonald, M.7
Yankner, B.8
Yuan, J.9
-
106
-
-
84863229947
-
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis
-
PMID:22249165
-
Kaushik S, Arias E, Kwon H, Lopez NM, Athonvarangkul D, Sahu S, Schwartz GJ, Pessin JE, Singh R. Loss of autophagy in hypothalamic POMC neurons impairs lipolysis. EMBO Rep 2012; 13:258-65; PMID:22249165; http://dx.doi.org/10.1038/ embor.2011.260
-
(2012)
EMBO Rep
, vol.13
, pp. 258-265
-
-
Kaushik, S.1
Arias, E.2
Kwon, H.3
Lopez, N.M.4
Athonvarangkul, D.5
Sahu, S.6
Schwartz, G.J.7
Pessin, J.E.8
Singh, R.9
-
107
-
-
77956274584
-
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
-
PMID:20660724
-
Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, et al. Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. Proc Natl Acad Sci U S A 2010; 107:14164-9; PMID:20660724; http://dx.doi.org/10.1073/pnas.1009485107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14164-14169
-
-
Lipinski, M.M.1
Zheng, B.2
Lu, T.3
Yan, Z.4
Py, B.F.5
Ng, A.6
Xavier, R.J.7
Li, C.8
Yankner, B.A.9
Scherzer, C.R.10
-
108
-
-
0032860808
-
The age-related accumulation of protein carbonyl in rat liver correlates with the age-related decline in liver proteolytic activities
-
PMID:10496537
-
Vittorini S, Paradiso C, Donati A, Cavallini G, Masini M, Gori Z, Pollera M, Bergamini E. The age-related accumulation of protein carbonyl in rat liver correlates with the age-related decline in liver proteolytic activities. J Gerontol A Biol Sci Med Sci 1999; 54:B318-23; PMID:10496537; http://dx.doi.org/10.1093/gerona/54.8.B318
-
(1999)
J Gerontol A Biol Sci Med Sci
, vol.54
-
-
Vittorini, S.1
Paradiso, C.2
Donati, A.3
Cavallini, G.4
Masini, M.5
Gori, Z.6
Pollera, M.7
Bergamini, E.8
-
109
-
-
65449117176
-
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
-
PMID:19229298
-
Gamerdinger M, Hajieva P, Kaya AM, Wolfrum U, Hartl FU, Behl C. Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. EMBO J 2009; 28:889-901; PMID:19229298; http://dx.doi.org/10.1038/ emboj.2009.29
-
(2009)
EMBO J
, vol.28
, pp. 889-901
-
-
Gamerdinger, M.1
Hajieva, P.2
Kaya, A.M.3
Wolfrum, U.4
Hartl, F.U.5
Behl, C.6
-
110
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
PMID:18059160
-
Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008; 4:176-84; PMID:18059160
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
111
-
-
77956241785
-
Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans
-
PMID:20346072
-
Yang W, Hekimi S. Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans. Aging Cell 2010; 9:433-47; PMID:20346072; http://dx.doi.org/10.1111/j.1474-9726.2010.00571.x
-
(2010)
Aging Cell
, vol.9
, pp. 433-447
-
-
Yang, W.1
Hekimi, S.2
-
112
-
-
84872566075
-
Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. Elegans
-
PMID:23247094
-
Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, et al. Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans. Exp Gerontol 2013; 48:191-201; PMID:23247094; http://dx.doi.org/10. 1016/j.exger.2012.12.002
-
(2013)
Exp Gerontol
, vol.48
, pp. 191-201
-
-
Schiavi, A.1
Torgovnick, A.2
Kell, A.3
Megalou, E.4
Castelein, N.5
Guccini, I.6
Marzocchella, L.7
Gelino, S.8
Hansen, M.9
Malisan, F.10
-
113
-
-
0037029072
-
Mitochondrial functions and aging
-
PMID:11943461
-
Osiewacz HD. Mitochondrial functions and aging. Gene 2002; 286:65-71; PMID:11943461; http://dx.doi.org/10.1016/S0378-1119(01)00804-6
-
(2002)
Gene
, vol.286
, pp. 65-71
-
-
Osiewacz, H.D.1
-
114
-
-
80053342165
-
Mitochondrial quality control in aging and lifespan control of the fungal aging model Podospora anserina
-
PMID:21936839
-
Osiewacz HD. Mitochondrial quality control in aging and lifespan control of the fungal aging model Podospora anserina. Biochem Soc Trans 2011; 39:1488-92; PMID:21936839; http://dx.doi.org/10.1042/BST0391488
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 1488-1492
-
-
Osiewacz, H.D.1
-
115
-
-
0037591619
-
Versatile EGFP reporter plasmids for cellular localization of recombinant gene products in filamentous fungi
-
PMID:12684845
-
Pöggeler S, Masloff S, Hoff B, Mayrhofer S, Kück U. Versatile EGFP reporter plasmids for cellular localization of recombinant gene products in filamentous fungi. Curr Genet 2003; 43:54-61; PMID:12684845
-
(2003)
Curr Genet
, vol.43
, pp. 54-61
-
-
Pöggeler, S.1
Masloff, S.2
Hoff, B.3
Mayrhofer, S.4
Kück, U.5
-
116
-
-
0028358576
-
A versatile shuttle cosmid vector for the efficient construction of genomic libraries and for the cloning of fungal genes
-
PMID:7954902
-
Osiewacz HD. A versatile shuttle cosmid vector for the efficient construction of genomic libraries and for the cloning of fungal genes. Curr Genet 1994; 26:87-90; PMID:7954902; http://dx.doi.org/10.1007/BF00326309
-
(1994)
Curr Genet
, vol.26
, pp. 87-90
-
-
Osiewacz, H.D.1
-
117
-
-
1242345186
-
Impact of a disruption of a pathway delivering copper to mitochondria on Podospora anserina metabolism and life span
-
PMID:14871950
-
Stumpferl SW, Stephan O, Osiewacz HD. Impact of a disruption of a pathway delivering copper to mitochondria on Podospora anserina metabolism and life span. Eukaryot Cell 2004; 3:200-11; PMID:14871950; http://dx.doi.org/10.1128/EC. 3.1.200-211.2004
-
(2004)
Eukaryot Cell
, vol.3
, pp. 200-211
-
-
Stumpferl, S.W.1
Stephan, O.2
Osiewacz, H.D.3
-
118
-
-
0034668869
-
A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans
-
PMID:11071951
-
Chaveroche MK, Ghigo JM, d'Enfert C. A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans. Nucleic Acids Res 2000; 28:E97; PMID:11071951; http://dx.doi.org/10.1093/nar/28.22.e97
-
(2000)
Nucleic Acids Res
, vol.28
-
-
Chaveroche, M.K.1
Ghigo, J.M.2
D'Enfert, C.3
-
119
-
-
0028069681
-
Rapid methods for nucleic acids extraction from Petri dish-grown mycelia
-
PMID:8087879
-
Lecellier G, Silar P. Rapid methods for nucleic acids extraction from Petri dish-grown mycelia. Curr Genet 1994; 25:122-3; PMID:8087879; http://dx.doi.org/10.1007/BF00309536
-
(1994)
Curr Genet
, vol.25
, pp. 122-123
-
-
Lecellier, G.1
Silar, P.2
-
120
-
-
52649084803
-
Over-expression of an S-adenosylmethionine-dependent methyltransferase leads to an extended lifespan of Podospora anserina without impairments in vital functions
-
PMID:18616635
-
Kunstmann B, Osiewacz HD. Over-expression of an S-adenosylmethionine- dependent methyltransferase leads to an extended lifespan of Podospora anserina without impairments in vital functions. Aging Cell 2008; 7:651-62; PMID:18616635; http://dx.doi.org/10.1111/j.1474-9726.2008.00412.x
-
(2008)
Aging Cell
, vol.7
, pp. 651-662
-
-
Kunstmann, B.1
Osiewacz, H.D.2
-
121
-
-
77955172060
-
Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy
-
PMID:20601950
-
Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EH. Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Nat Methods 2010; 7:637-42; PMID:20601950; http://dx.doi.org/10.1038/nmeth.1476
-
(2010)
Nat Methods
, vol.7
, pp. 637-642
-
-
Keller, P.J.1
Schmidt, A.D.2
Santella, A.3
Khairy, K.4
Bao, Z.5
Wittbrodt, J.6
Stelzer, E.H.7
|