The bip molecular chaperone plays multiple roles during the biogenesis of torsina, an aaa atpase associated with the neurological disease early-onset torsion dystonia

Journal of Biological Chemistry

Volumn 289, Issue 18, 2014, Pages 12727-12747

  Zacchi, Lucía F ^a   Wu, Hui Chuan ^b   Bell, Samantha L ^a   Millen, Linda ^c   Paton, Adrienne W ^d   Paton, James C ^d   Thomas, Philip J ^c   Zolkiewski, Michal ^b   Brodsky, Jeffrey L ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLOGY;

MOLECULAR CHAPERONES; NEUROLOGICAL DISEASE;

TORSIONAL STRESS;

ADENOSINE TRIPHOSPHATASE; CHAPERONE; GLUTAMIC ACID; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; TORSIN A; UNCLASSIFIED DRUG;

ABNORMAL POSTURE; ARTICLE; BIOGENESIS; DISEASE PREDISPOSITION; ENDOPLASMIC RETICULUM; GENE DELETION; GENE EXPRESSION SYSTEM; GENE MUTATION; GLYCOSYLATION; HUMAN; MUSCLE CONTRACTION; NEUROLOGIC DISEASE; PARALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; SOLUBILITY; TORSION DYSTONIA;

BIP; DYT1; GRP78; MOLECULAR CHAPERONE; NEUROLOGICAL DISEASES; PROTEIN DEGRADATION; PROTEIN FOLDING; TORSINA; YEAST;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BLOTTING, WESTERN; CELL LINE; DYSTONIA MUSCULORUM DEFORMANS; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HEAT-SHOCK PROTEINS; HELA CELLS; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; MUTATION; PROTEIN STABILITY; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84899745499     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.529123     Document Type: Article

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