AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP

Nature

Volumn 443, Issue 7111, 2006, Pages 548-552

  Paton, Adrienne W ^a   Beddoe, Travis ^b   Thorpe, Cheleste M ^c   Whisstock, James C ^b   Wilce, Matthew C J ^b   Rossjohn, Jamie ^b   Talbot, Ursula M ^a   Paton, James C ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; ENZYMES; ESCHERICHIA COLI; PATHOLOGY;

ENDOPLASMIC RETICULUM; EUKARYOTIC CELLS; SUBTILASE CYTOTOXIN;

TOXIC MATERIALS;

AB5 SUBTILASE CYTOTOXIN; CHAPERONE; CYTOTOXIN; GLUCOSE REGULATED PROTEIN 78; SERINE PROTEINASE; UNCLASSIFIED DRUG; BACTERIAL TOXIN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; SUBTILISIN;

AMINO ACID; BACTERIUM; CELL ORGANELLE; ENZYME ACTIVITY; PROTEIN; TOXIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBUNIT; EUKARYOTIC CELL; GENE INACTIVATION; GENETIC TRANSFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; TARGET CELL; ANIMAL; BINDING SITE; CATTLE; CERCOPITHECUS; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; MOUSE; MUTAGENESIS; PATHOGENICITY; VERO CELL;

ESCHERICHIA COLI; EUKARYOTA;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CATTLE; CERCOPITHECUS AETHIOPS; CYTOTOXINS; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI; HEAT-SHOCK PROTEINS; MICE; MOLECULAR CHAPERONES; MUTAGENESIS; SUBSTRATE SPECIFICITY; SUBTILISIN; VERO CELLS;

EID: 33749522548     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05124     Document Type: Article

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