The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein

Journal of Cell Biology

Volumn 168, Issue 6, 2005, Pages 855-862

  Goodchild, Rose E ^a   Dauer, William T ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ENDOPLASMIC RETICULUM PROTEIN; LAMINA ASSOCIATED POLYPEPTIDE 1; PROTEIN AAA; PROTEIN TORSINA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DYSTONIA; EMBRYO; ENDOPLASMIC RETICULUM; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL LINE; CONSERVED SEQUENCE; CRICETINAE; ENDOPLASMIC RETICULUM; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GREEN FLUORESCENT PROTEINS; HELA CELLS; HSC70 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KINETICS; MEMBRANE PROTEINS; MICE; MICROSCOPY, CONFOCAL; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; NUCLEAR ENVELOPE; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION;

ANIMALIA;

EID: 15444374750     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200411026     Document Type: Article

References (22)

1. Berardelli, A., J.C. Rothwell, M. Hallett, P.D. Thompson, M. Manfredi, and C.D. Marsden. 1998. The pathophysiology of primary dystonia. Brain. 121:1195-1212.
2. Burke, B., and C.L. Stewart. 2002. Life at the edge: the nuclear envelope and human disease. Nat. Rev. Mol. Cell Biol. 3:575-585.
3. Daigle, N., J. Beaudouin, L. Hartnell, G. Imreh, E. Hallberg, J. Lippincott-Schwartz, and J. Ellenberg. 2001. Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells. J. Cell Biol. 154:71-84.
4. De Sandre-Giovannoli, A., R. Bernard, P. Cau, C. Navarro, J. Amiel, I. Boccaccio, S. Lyonnet, C.L. Stewart, A. Munnich, M. Le Merrer, and N. Levy. 2003. Lamin a truncation in Hutchinson-Gilford progeria. Science. 300:2055.
5. Ellenberg, J., E.D. Siggia, J.E. Moreira, C.L. Smith, J.F. Presley, H.J. Worman, and J. Lippincott-Schwartz. 1997. Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis. J. Cell Biol. 138:1193-1206.
6. Fahn, S., C.D. Marsden, and D.B. Calne. 1987. Classification and investigation of dystonia. In Movement Disorders 2. C.D. Marsden and S. Fahn, editors. Butterworths, London. 332-358.
7. Fitzgerald, J., D. Kennedy, N. Viseshakul, B.N. Cohen, J. Mattick, J.F. Bateman, and J.R. Forsayeth. 2000. UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein. Brain Res. 877:110-123.
8. Foisner, R., and L. Gerace. 1993. Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell. 73:1267-1279.
9. Gerace, L. 2004. TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope. Proc. Natl. Acad. Sci. USA. 101:8839-8840.
10. Goodchild, R.E., and W.T. Dauer. 2004. Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation. Proc. Natl. Acad. Sci. USA. 101:847-852.
11. Kondo, Y., J. Kondoh, D. Hayashi, T. Ban, M. Takagi, Y. Kamei, L. Tsuji, J. Kim, and Y. Yoneda. 2002. Molecular cloning of one isotype of human lamina-associated polypeptide Is and a topological analysis using its deletion mutants. Biochem. Biophys. Res. Commun. 294:770-778.
12. Martin, L., C. Crimaudo, and L. Gerace. 1995. cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane. J. Biol. Chem. 270:8822-8828.
13. Naismith, T.V., J.E. Heuser, X.O. Breakefield, and P.I. Hanson. 2004. TorsinA in the nuclear envelope. Proc. Natl. Acad. Sci. USA. 101:7612-7617.
14. Östlund, C., J. Ellenberg, E. Hallberg, J. Lippincott-Schwartz, and H.J. Worman. 1999. Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein. J. Cell Sci. 112:1709-1719.
15. Ozelius, L.J., J.W. Hewett, C.E. Page, S.B. Bressman, P.L. Kramer, C. Shalish, D. de Leon, M.F. Brin, D. Raymond, D.P. Corey, et al. 1997. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat. Genet. 17:40-48.
16. Schirmer, E.C., L. Florens, T. Guan, J.R. Yates III, and L. Gerace. 2003. Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science. 301:1380-1382.
17. Senior, A., and L. Gerace. 1988. Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamina. J. Cell Biol. 107:2029-2036.
18. Shimi, T., T. Koujin, M. Segura-Totten, K.L. Wilson, T. Haraguchi, and Y. Hiraoka. 2004. Dynamic interaction between BAF and emerin revealed by FRAP, FLIP, and FRET analyses in living HeLa cells. J. Struct. Biol. 147:31-41.
19. Sullivan, T., D. Escalante-Alcalde, H. Bhatt, M. Anver, N. Bhat, K. Nagashima, C.L. Stewart, and B. Burke. 1999. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J. Cell Biol. 147:913-920.
20. Vale, R.D. 2000. AAA proteins. Lords of the ring. J. Cell Biol. 150:F13-F19.
21. Whiteheart, S.W., K. Rossnagel, S.A. Buhrow, M. Brunner, R. Jaenicke, and J.E. Rothman. 1994. N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. J. Cell Biol. 126:945-954.
22. Wozniak, R.W., and G. Blobel. 1992. The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope. J. Cell Biol. 119:1441-1449.