Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 27, 2009, Pages 11061-11066

  Schulz, Benjamin L ^a   Stirnimann, Christian U ^b   Grimshaw, John P A ^a   Brozzo, Maurice S ^a   Fritsch, Fabienne ^a   Mohorko, Elisabeth ^a   Capitani, Guido ^b   Glockshuber, Rudi ^a   Grütter, Markus G ^b   Aebi, Markus ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Crystal structure; Mass spectrometry; N glycosylation; Protein folding; Thioredoxin like protein

Indexed keywords

CYSTEINE; FUNGAL ENZYME; OLIGOSACCHARYLTRANSFERASE 3P; OLIGOSACCHARYLTRANSFERASE 6P; OXIDOREDUCTASE; THIOREDOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME GLYCOSYLATION; ENZYME STRUCTURE; ENZYME SUBUNIT; GENE MUTATION; MOLECULAR MECHANICS; NONHUMAN; OXIDATION REDUCTION STATE; PARALOGY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION;

AMINO ACID MOTIFS; CATALYTIC DOMAIN; GLYCOSYLATION; HEXOSYLTRANSFERASES; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; OXIDOREDUCTASES; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SULFHYDRYL COMPOUNDS;

EUKARYOTA;

EID: 67650498261     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0812515106     Document Type: Article

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