메뉴 건너뛰기




Volumn 211, Issue 5, 2014, Pages 887-907

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR;

EID: 84899733210     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131314     Document Type: Article
Times cited : (70)

References (125)
  • 1
    • 0034534961 scopus 로고    scopus 로고
    • Nitric oxide is a physiological substrate for mammalian peroxidases
    • Abu-Soud, H.M., and S.L. Hazen. 2000a. Nitric oxide is a physiological substrate for mammalian peroxidases. J. Biol. Chem. http://dx.doi.org/10.1074/jbc.275.48.37524 275:37524-37532
    • (2000) J. Biol. Chem , vol.275 , pp. 37524-37532
    • Abu-Soud, H.M.1    Hazen, S.L.2
  • 2
    • 0034102068 scopus 로고    scopus 로고
    • Nitric oxide modulates the catalytic activity of myeloperoxidase
    • Abu-Soud, H.M., and S.L. Hazen. 2000b. Nitric oxide modulates the catalytic activity of myeloperoxidase. J. Biol. Chem. http://dx.doi.org/10.1074/jbc.275.8.5425 275:5425-5430
    • (2000) J. Biol. Chem. , vol.275 , pp. 5425-5430
    • Abu-Soud, H.M.1    Hazen, S.L.2
  • 3
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
    • Aird, W.C. 2007. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ. Res. http://dx.doi.org/10.1161/01.RES.0000255691.76142.4a 100:158-173
    • (2007) Circ. Res. , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 5
    • 43049156331 scopus 로고    scopus 로고
    • Cardiovascular risk in rheumatoid arthritis: effects of anti-TNF drugs
    • Avouac, J., and Y. Allanore. 2008. Cardiovascular risk in rheumatoid arthritis: effects of anti-TNF drugs. Expert Opin. Pharmacother. http://dx.doi.org/10.1517/14656566.9.7.1121 9:1121-1128
    • (2008) Expert Opin. Pharmacother. , vol.9 , pp. 1121-1128
    • Avouac, J.1    Allanore, Y.2
  • 6
    • 0141727730 scopus 로고    scopus 로고
    • Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
    • and C. Investigators; CAPTURE Investigators
    • Baldus, S., C. Heeschen, T. Meinertz, A.M. Zeiher, J.P. Eiserich, T. Münzel, M.L. Simoons, C.W. Hamm, and C. Investigators; CAPTURE Investigators. 2003. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation. http://dx.doi.org/10.1161/01.CIR.0000090690.67322.51 108:1440-1445
    • (2003) Circulation , vol.108 , pp. 1440-1445
    • Baldus, S.1    Heeschen, C.2    Meinertz, T.3    Zeiher, A.M.4    Eiserich, J.P.5    Münzel, T.6    Simoons, M.L.7    Hamm, C.W.8
  • 10
    • 79954577277 scopus 로고    scopus 로고
    • TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk
    • Brown, J., H. Wang, G.N. Hajishengallis, and M. Martin. 2011. TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J. Dent. Res. http://dx.doi.org/10.1177/0022034510381264 90:417-427
    • (2011) J. Dent. Res. , vol.90 , pp. 417-427
    • Brown, J.1    Wang, H.2    Hajishengallis, G.N.3    Martin, M.4
  • 11
    • 0032774697 scopus 로고    scopus 로고
    • Effects of sex and age on atherosclerosis and autoimmunity in apoE-deficient mice
    • Caligiuri, G., A. Nicoletti, X. Zhou, I. Törnberg, and G.K. Hansson. 1999. Effects of sex and age on atherosclerosis and autoimmunity in apoE-deficient mice. Atherosclerosis. http://dx.doi.org/10.1016/S0021-9150(99)00081-7 145:301-308
    • (1999) Atherosclerosis , vol.145 , pp. 301-308
    • Caligiuri, G.1    Nicoletti, A.2    Zhou, X.3    Törnberg, I.4    Hansson, G.K.5
  • 13
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani, P.D., R. Bibiloni, C. Knauf, A. Waget, A.M. Neyrinck, N.M. Delzenne, and R. Burcelin. 2008. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes. http://dx.doi.org/10.2337/db07-1403 57:1470-1481
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6    Burcelin, R.7
  • 14
    • 33644695684 scopus 로고    scopus 로고
    • Whole-body insulin resistance in the absence of obesity in FVB mice with overexpression of Dgat1 in adipose tissue
    • Chen, N., L. Liu, Y. Zhang, H.N. Ginsberg, and Y.H. Yu. 2005. Whole-body insulin resistance in the absence of obesity in FVB mice with overexpression of Dgat1 in adipose tissue. Diabetes. http://dx.doi.org/10.2337/diabetes.54.12.3379 54:3379-3386
    • (2005) Diabetes , vol.54 , pp. 3379-3386
    • Chen, N.1    Liu, L.2    Zhang, Y.3    Ginsberg, H.N.4    Yu, Y.H.5
  • 15
    • 0034033039 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase
    • Cheung, A.T., J. Wang, D. Ree, J.K. Kolls, and M. Bryer-Ash. 2000. Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase. Diabetes. http://dx.doi.org/10.2337/diabetes.49.5.810 49:810-819
    • (2000) Diabetes , vol.49 , pp. 810-819
    • Cheung, A.T.1    Wang, J.2    Ree, D.3    Kolls, J.K.4    Bryer-Ash, M.5
  • 16
    • 4644280450 scopus 로고    scopus 로고
    • Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications
    • Chi, H., E. Messas, R.A. Levine, D.T. Graves, and S. Amar. 2004. Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications. Circulation. http://dx.doi.org/10.1161/01.CIR.0000142085.39015.31 110:1678-1685
    • (2004) Circulation , vol.110 , pp. 1678-1685
    • Chi, H.1    Messas, E.2    Levine, R.A.3    Graves, D.T.4    Amar, S.5
  • 17
    • 80052761810 scopus 로고    scopus 로고
    • Macrophage polarization in metabolic disorders: functions and regulation
    • Chinetti-Gbaguidi, G., and B. Staels. 2011. Macrophage polarization in metabolic disorders: functions and regulation. Curr. Opin. Lipidol. http://dx.doi.org/10.1097/MOL.0b013e32834a77b4 22:365-372
    • (2011) Curr. Opin. Lipidol. , vol.22 , pp. 365-372
    • Chinetti-Gbaguidi, G.1    Staels, B.2
  • 18
    • 30044448462 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 in immunity and inflammation
    • Chitu, V., and E.R. Stanley. 2006. Colony-stimulating factor-1 in immunity and inflammation. Curr. Opin. Immunol. http://dx.doi.org/10.1016/j.coi.2005.11.006 18:39-48
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 39-48
    • Chitu, V.1    Stanley, E.R.2
  • 20
    • 84855481978 scopus 로고    scopus 로고
    • Toll-like receptors and diabetes: a therapeutic perspective
    • Dasu, M.R., S. Ramirez, and R.R. Isseroff. 2012. Toll-like receptors and diabetes: a therapeutic perspective. Clin. Sci. http://dx.doi.org/10.1042/CS20110357 122:203-214
    • (2012) Clin. Sci. , vol.122 , pp. 203-214
    • Dasu, M.R.1    Ramirez, S.2    Isseroff, R.R.3
  • 22
    • 34347384513 scopus 로고    scopus 로고
    • What effects might anti-TNFalpha treatment be expected to have on cardiovascular morbidity and mortality in rheumatoid arthritis? A review of the role of TNFalpha in cardiovascular pathophysiology
    • Dixon, W.G., and D.P. Symmons. 2007. What effects might anti-TNFalpha treatment be expected to have on cardiovascular morbidity and mortality in rheumatoid arthritis? A review of the role of TNFalpha in cardiovascular pathophysiology. Ann. Rheum. Dis. http://dx.doi.org/10.1136/ard.2006.063867 66:1132-1136
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 1132-1136
    • Dixon, W.G.1    Symmons, D.P.2
  • 24
    • 0032570269 scopus 로고    scopus 로고
    • Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice
    • Elhage, R., A. Maret, M.T. Pieraggi, J.C. Thiers, J.F. Arnal, and F. Bayard. 1998. Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice. Circulation. http://dx.doi.org/10.1161/01.CIR.97.3.242 97:242-244
    • (1998) Circulation , vol.97 , pp. 242-244
    • Elhage, R.1    Maret, A.2    Pieraggi, M.T.3    Thiers, J.C.4    Arnal, J.F.5    Bayard, F.6
  • 25
  • 26
    • 79955531353 scopus 로고    scopus 로고
    • Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease
    • Erridge, C. 2011. Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease. Atherosclerosis. http://dx.doi.org/10.1016/j.atherosclerosis.2011.02.043 216:1-6
    • (2011) Atherosclerosis , vol.216 , pp. 1-6
    • Erridge, C.1
  • 27
    • 0034101821 scopus 로고    scopus 로고
    • Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
    • Febbraio, M., E.A. Podrez, J.D. Smith, D.P. Hajjar, S.L. Hazen, H.F. Hoff, K. Sharma, and R.L. Silverstein. 2000. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J. Clin. Invest. http://dx.doi.org/10.1172/JCI9259 105:1049-1056
    • (2000) J. Clin. Invest. , vol.105 , pp. 1049-1056
    • Febbraio, M.1    Podrez, E.A.2    Smith, J.D.3    Hajjar, D.P.4    Hazen, S.L.5    Hoff, H.F.6    Sharma, K.7    Silverstein, R.L.8
  • 28
    • 10644255811 scopus 로고    scopus 로고
    • Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis
    • Febbraio, M., E. Guy, and R.L. Silverstein. 2004. Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.0000148007.06370.68 24:2333-2338
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 2333-2338
    • Febbraio, M.1    Guy, E.2    Silverstein, R.L.3
  • 30
    • 71349086382 scopus 로고    scopus 로고
    • Long-term anti-tumour necrosis factor therapy reverses the progression of carotid intima-media thickness in female patients with active rheumatoid arthritis
    • Ferrante, A., A.R. Giardina, F. Ciccia, G. Parrinello, G. Licata, G. Avellone, E. Giardina, R. Impastato, and G. Triolo. 2009. Long-term anti-tumour necrosis factor therapy reverses the progression of carotid intima-media thickness in female patients with active rheumatoid arthritis. Rheumatol. Int. http://dx.doi.org/10.1007/s00296-009-0935-2 30:193-198
    • (2009) Rheumatol. Int. , vol.30 , pp. 193-198
    • Ferrante, A.1    Giardina, A.R.2    Ciccia, F.3    Parrinello, G.4    Licata, G.5    Avellone, G.6    Giardina, E.7    Impastato, R.8    Triolo, G.9
  • 31
    • 0037087449 scopus 로고    scopus 로고
    • Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma
    • Fischer, B., A. Von Knethen, and B. Brüne. 2002. Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. J. Immunol. 168:2828-2834
    • (2002) J. Immunol. , vol.168 , pp. 2828-2834
    • Fischer, B.1    Von Knethen, A.2    Brüne, B.3
  • 32
    • 34247124840 scopus 로고    scopus 로고
    • Granulocytemacrophage colony-stimulating factor (CSF) and macrophage CSFdependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation
    • Fleetwood, A.J., T. Lawrence, J.A. Hamilton, and A.D. Cook. 2007. Granulocytemacrophage colony-stimulating factor (CSF) and macrophage CSFdependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation. J. Immunol. 178:5245-5252
    • (2007) J. Immunol. , vol.178 , pp. 5245-5252
    • Fleetwood, A.J.1    Lawrence, T.2    Hamilton, J.A.3    Cook, A.D.4
  • 33
    • 57649138445 scopus 로고    scopus 로고
    • The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation
    • Fraczek, J., T.W. Kim, H. Xiao, J. Yao, Q. Wen, Y. Li, J.L. Casanova, J. Pryjma, and X. Li. 2008. The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation. J. Biol. Chem. http://dx.doi.org/10.1074/jbc. M804779200 283:31697-31705
    • (2008) J. Biol. Chem. , vol.283 , pp. 31697-31705
    • Fraczek, J.1    Kim, T.W.2    Xiao, H.3    Yao, J.4    Wen, Q.5    Li, Y.6    Casanova, J.L.7    Pryjma, J.8    Li, X.9
  • 34
    • 79959267977 scopus 로고    scopus 로고
    • Toll-like receptors, inflammation, metabolism and obesity
    • Fresno, M., R. Alvarez, and N. Cuesta. 2011. Toll-like receptors, inflammation, metabolism and obesity. Arch. Physiol. Biochem. http://dx.doi.org/10.3109/13813455.2011.562514 117:151-164
    • (2011) Arch. Physiol. Biochem. , vol.117 , pp. 151-164
    • Fresno, M.1    Alvarez, R.2    Cuesta, N.3
  • 36
    • 33646692002 scopus 로고    scopus 로고
    • Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent
    • Galkina, E., A. Kadl, J. Sanders, D. Varughese, I.J. Sarembock, and K. Ley. 2006. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J. Exp. Med. http://dx.doi.org/10.1084/jem.20052205 203:1273-1282
    • (2006) J. Exp. Med. , vol.203 , pp. 1273-1282
    • Galkina, E.1    Kadl, A.2    Sanders, J.3    Varughese, D.4    Sarembock, I.J.5    Ley, K.6
  • 37
    • 44649105230 scopus 로고    scopus 로고
    • Arginase I induction by modified lipoproteins in macrophages: a peroxisome proliferator-activated receptorgamma/delta-mediated effect that links lipid metabolism and immunity
    • Gallardo-Soler, A., C. Gómez-Nieto, M.L. Campo, C. Marathe, P. Tontonoz, A. Castrillo, and I. Corraliza. 2008. Arginase I induction by modified lipoproteins in macrophages: a peroxisome proliferator-activated receptorgamma/delta-mediated effect that links lipid metabolism and immunity. Mol. Endocrinol. http://dx.doi.org/10.1210/me.2007-0525 22:1394-1402
    • (2008) Mol. Endocrinol , vol.22 , pp. 1394-1402
    • Gallardo-Soler, A.1    Gómez-Nieto, C.2    Campo, M.L.3    Marathe, C.4    Tontonoz, P.5    Castrillo, A.6    Corraliza, I.7
  • 38
    • 79952100792 scopus 로고    scopus 로고
    • What the Myddosome structure tells us about the initiation of innate immunity
    • Gay, N.J., M. Gangloff, and L.A. O'Neill. 2011. What the Myddosome structure tells us about the initiation of innate immunity. Trends Immunol. http://dx.doi.org/10.1016/j.it.2010.12.005 32:104-109
    • (2011) Trends Immunol , vol.32 , pp. 104-109
    • Gay, N.J.1    Gangloff, M.2    O'Neill, L.A.3
  • 39
    • 34247195133 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor exacerbate atherosclerosis in apolipoprotein E-deficient mice
    • Haghighat, A., D. Weiss, M.K. Whalin, D.P. Cowan, and W.R. Taylor. 2007. Granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor exacerbate atherosclerosis in apolipoprotein E-deficient mice. Circulation. http://dx.doi.org/10.1161/CIRCULATIONAHA.106.665570 115:2049-2054
    • (2007) Circulation , vol.115 , pp. 2049-2054
    • Haghighat, A.1    Weiss, D.2    Whalin, M.K.3    Cowan, D.P.4    Taylor, W.R.5
  • 40
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • Hamilton, J.A. 2008. Colony-stimulating factors in inflammation and autoimmunity. Nat. Rev. Immunol. http://dx.doi.org/10.1038/nri2356 8:533-544
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 533-544
    • Hamilton, J.A.1
  • 41
    • 0032923922 scopus 로고    scopus 로고
    • Oxidized LDL can induce macrophage survival, DNA synthesis, and enhanced proliferative response to CSF-1 and GM-CSF
    • Hamilton, J.A., D. Myers, W. Jessup, F. Cochrane, R. Byrne, G. Whitty, and S. Moss. 1999. Oxidized LDL can induce macrophage survival, DNA synthesis, and enhanced proliferative response to CSF-1 and GM-CSF. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.19.1.98 19:98-105
    • (1999) Arterioscler. Thromb. Vasc. Biol , vol.19 , pp. 98-105
    • Hamilton, J.A.1    Myers, D.2    Jessup, W.3    Cochrane, F.4    Byrne, R.5    Whitty, G.6    Moss, S.7
  • 42
    • 33745053205 scopus 로고    scopus 로고
    • Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway
    • Harari, O.A., P. Alcaide, D. Ahl, F.W. Luscinskas, and J.K. Liao. 2006. Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway. Circ. Res. http://dx.doi.org/10.1161/01.RES.0000220105.85182.28 98:1134-1140
    • (2006) Circ. Res. , vol.98 , pp. 1134-1140
    • Harari, O.A.1    Alcaide, P.2    Ahl, D.3    Luscinskas, F.W.4    Liao, J.K.5
  • 43
    • 0037477790 scopus 로고    scopus 로고
    • Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice
    • Hatley, M.E., S. Srinivasan, K.B. Reilly, D.T. Bolick, and C.C. Hedrick. 2003. Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. J. Biol. Chem. 278:25369-25375
    • (2003) J. Biol. Chem. , vol.278 , pp. 25369-25375
    • Hatley, M.E.1    Srinivasan, S.2    Reilly, K.B.3    Bolick, D.T.4    Hedrick, C.C.5
  • 44
    • 0030979720 scopus 로고    scopus 로고
    • 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima
    • Hazen, S.L., and J.W. Heinecke. 1997. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J. Clin. Invest. http://dx.doi.org/10.1172/JCI119379 99:2075-2081
    • (1997) J. Clin. Invest. , vol.99 , pp. 2075-2081
    • Hazen, S.L.1    Heinecke, J.W.2
  • 45
    • 0002019504 scopus 로고    scopus 로고
    • Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols
    • Hazen, S.L., F.F. Hsu, K. Duffin, and J.W. Heinecke. 1996. Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols. J. Biol. Chem. http://dx.doi.org/10.1074/jbc.271.38.23080 271:23080-23088
    • (1996) J. Biol. Chem. , vol.271 , pp. 23080-23088
    • Hazen, S.L.1    Hsu, F.F.2    Duffin, K.3    Heinecke, J.W.4
  • 46
    • 0032739169 scopus 로고    scopus 로고
    • Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes: pathways for monocyte-mediated protein nitration and lipid peroxidation In vivo
    • Hazen, S.L., R. Zhang, Z. Shen, W. Wu, E.A. Podrez, J.C. MacPherson, D. Schmitt, S.N. Mitra, C. Mukhopadhyay, Y. Chen, et al. 1999. Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes: pathways for monocyte-mediated protein nitration and lipid peroxidation In vivo. Circ. Res. http://dx.doi.org/10.1161/01.RES.85.10.950 85:950-958
    • (1999) Circ. Res. , vol.85 , pp. 950-958
    • Hazen, S.L.1    Zhang, R.2    Shen, Z.3    Wu, W.4    Podrez, E.A.5    MacPherson, J.C.6    Schmitt, D.7    Mitra, S.N.8    Mukhopadhyay, C.9    Chen, Y.10
  • 47
    • 77952315676 scopus 로고    scopus 로고
    • Tlr2 is critical for diet-induced metabolic syndrome in a murine model
    • Himes, R.W., and C.W. Smith. 2010. Tlr2 is critical for diet-induced metabolic syndrome in a murine model. FASEB J. http://dx.doi.org/10.1096/fj.09-141929 24:731-739
    • (2010) FASEB J , vol.24 , pp. 731-739
    • Himes, R.W.1    Smith, C.W.2
  • 49
    • 44249104442 scopus 로고    scopus 로고
    • Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome
    • Holvoet, P., D.H. Lee, M. Steffes, M. Gross, and D.R. Jacobs Jr. 2008. Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA. http://dx.doi.org/10.1001/jama.299.19.2287 299:2287-2293
    • (2008) JAMA , vol.299 , pp. 2287-2293
    • Holvoet, P.1    Lee, D.H.2    Steffes, M.3    Gross, M.4    Jacobs Jr., D.R.5
  • 50
    • 77958536355 scopus 로고    scopus 로고
    • Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice
    • Hosoi, T., S. Yokoyama, S. Matsuo, S. Akira, and K. Ozawa. 2010. Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. PLoS ONE. http://dx.doi.org/10.1371/journal.pone.0012537 5:5
    • (2010) PLoS ONE , vol.5 , pp. 5
    • Hosoi, T.1    Yokoyama, S.2    Matsuo, S.3    Akira, S.4    Ozawa, K.5
  • 51
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil, G.S. 2006. Inflammation and metabolic disorders. Nature. http://dx.doi.org/10.1038/nature05485 444:860-867
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 52
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
    • Hotamisligil, G.S., N.S. Shargill, and B.M. Spiegelman. 1993. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. http://dx.doi.org/10.1126/science.7678183 259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 53
    • 48749132777 scopus 로고    scopus 로고
    • Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms
    • Hou, B., B. Reizis, and A.L. DeFranco. 2008. Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity. http://dx.doi.org/10.1016/j.immuni.2008.05.016 29:272-282
    • (2008) Immunity , vol.29 , pp. 272-282
    • Hou, B.1    Reizis, B.2    DeFranco, A.L.3
  • 55
    • 80052774978 scopus 로고    scopus 로고
    • The Dynamics of Oxidized LDL during Atherogenesis
    • Itabe, H., T. Obama, and R. Kato. 2011. The Dynamics of Oxidized LDL during Atherogenesis. J. Lipids. http://dx.doi.org/10.1155/2011/418313 2011:418313
    • (2011) J. Lipids , vol.2011 , pp. 418313
    • Itabe, H.1    Obama, T.2    Kato, R.3
  • 56
    • 33845873659 scopus 로고    scopus 로고
    • Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
    • Jager, J., T. Grémeaux, M. Cormont, Y. Le Marchand-Brustel, and J.F. Tanti. 2007. Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression. Endocrinology. http://dx.doi.org/10.1210/en.2006-0692 148:241-251
    • (2007) Endocrinology , vol.148 , pp. 241-251
    • Jager, J.1    Grémeaux, T.2    Cormont, M.3    Le Marchand-Brustel, Y.4    Tanti, J.F.5
  • 57
    • 77949973725 scopus 로고    scopus 로고
    • Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis
    • Kang, Z., C.Z. Altuntas, M.F. Gulen, C. Liu, N. Giltiay, H. Qin, L. Liu, W. Qian, R.M. Ransohoff, C. Bergmann, et al. 2010. Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis. Immunity. http://dx.doi.org/10.1016/j.immuni.2010.03.004 32:414-425
    • (2010) Immunity , vol.32 , pp. 414-425
    • Kang, Z.1    Altuntas, C.Z.2    Gulen, M.F.3    Liu, C.4    Giltiay, N.5    Qin, H.6    Liu, L.7    Qian, W.8    Ransohoff, R.M.9    Bergmann, C.10
  • 58
    • 84861460945 scopus 로고    scopus 로고
    • Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population
    • Kang, Z., S. Swaidani, W. Yin, C. Wang, J.L. Barlow, M.F. Gulen, K. Bulek, J.S. Do, M. Aronica, A.N. McKenzie, et al. 2012. Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population. Immunity. http://dx.doi.org/10.1016/j.immuni.2012.03.021 36:821-833
    • (2012) Immunity , vol.36 , pp. 821-833
    • Kang, Z.1    Swaidani, S.2    Yin, W.3    Wang, C.4    Barlow, J.L.5    Gulen, M.F.6    Bulek, K.7    Do, J.S.8    Aronica, M.9    McKenzie, A.N.10
  • 60
    • 33745116619 scopus 로고    scopus 로고
    • Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis
    • Karaskov, E., C. Scott, L. Zhang, T. Teodoro, M. Ravazzola, and A. Volchuk. 2006. Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology. 147:3398-3407
    • (2006) Endocrinology , vol.147 , pp. 3398-3407
    • Karaskov, E.1    Scott, C.2    Zhang, L.3    Teodoro, T.4    Ravazzola, M.5    Volchuk, A.6
  • 61
    • 51349158231 scopus 로고    scopus 로고
    • Signalling adaptors used by Toll-like receptors: an update
    • Kenny, E.F., and L.A. O'Neill. 2008. Signalling adaptors used by Toll-like receptors: an update. Cytokine. http://dx.doi.org/10.1016/j.cyto.2008.07.010 43:342-349
    • (2008) Cytokine , vol.43 , pp. 342-349
    • Kenny, E.F.1    O'Neill, L.A.2
  • 66
    • 48749110858 scopus 로고    scopus 로고
    • Cytokines and atherosclerosis: a comprehensive review of studies in mice
    • Kleemann, R., S. Zadelaar, and T. Kooistra. 2008. Cytokines and atherosclerosis: a comprehensive review of studies in mice. Cardiovasc. Res. http://dx.doi.org/10.1093/cvr/cvn120 79:360-376
    • (2008) Cardiovasc. Res. , vol.79 , pp. 360-376
    • Kleemann, R.1    Zadelaar, S.2    Kooistra, T.3
  • 67
    • 0242268894 scopus 로고    scopus 로고
    • Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
    • Klover, P.J., T.A. Zimmers, L.G. Koniaris, and R.A. Mooney. 2003. Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes. http://dx.doi.org/10.2337/diabetes.52.11.2784 52:2784-2789
    • (2003) Diabetes , vol.52 , pp. 2784-2789
    • Klover, P.J.1    Zimmers, T.A.2    Koniaris, L.G.3    Mooney, R.A.4
  • 68
    • 78650472774 scopus 로고    scopus 로고
    • Toll-like receptors: linking inflammation to metabolism
    • Könner, A.C., and J.C. Brüning. 2011. Toll-like receptors: linking inflammation to metabolism. Trends Endocrinol. Metab. http://dx.doi.org/10.1016/j.tem.2010.08.007 22:16-23
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 16-23
    • Könner, A.C.1    Brüning, J.C.2
  • 71
    • 67849128552 scopus 로고    scopus 로고
    • Lipolysis and lipid mobilization in human adipose tissue
    • Lafontan, M., and D. Langin. 2009. Lipolysis and lipid mobilization in human adipose tissue. Prog. Lipid Res. http://dx.doi.org/10.1016/j.plipres.2009.05.001 48:275-297
    • (2009) Prog. Lipid Res. , vol.48 , pp. 275-297
    • Lafontan, M.1    Langin, D.2
  • 72
    • 33746736936 scopus 로고    scopus 로고
    • Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes
    • Lagathu, C., L. Yvan-Charvet, J.P. Bastard, M. Maachi, A. Quignard-Boulangé, J. Capeau, and M. Caron. 2006. Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes. Diabetologia. http://dx.doi.org/10.1007/s00125-006-0335-z 49:2162-2173
    • (2006) Diabetologia , vol.49 , pp. 2162-2173
    • Lagathu, C.1    Yvan-Charvet, L.2    Bastard, J.P.3    Maachi, M.4    Quignard-Boulangé, A.5    Capeau, J.6    Caron, M.7
  • 73
    • 0025047387 scopus 로고
    • Increased insulin resistance and fat cell lipolysis in obese but not lean women with a high waist/hip ratio
    • Landin, K., P. Lönnroth, M. Krotkiewski, G. Holm, and U. Smith. 1990. Increased insulin resistance and fat cell lipolysis in obese but not lean women with a high waist/hip ratio. Eur. J. Clin. Invest. http://dx.doi.org/10.1111/j.1365-2362.1990.tb01922.x 20:530-535
    • (1990) Eur. J. Clin. Invest. , vol.20 , pp. 530-535
    • Landin, K.1    Lönnroth, P.2    Krotkiewski, M.3    Holm, G.4    Smith, U.5
  • 74
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
    • Lin, S.C., Y.C. Lo, and H. Wu. 2010. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. http://dx.doi.org/10.1038/nature09121 465:885-890
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 75
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng, C.N., J.L. Bodzin, and A.R. Saltiel. 2007. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. http://dx.doi.org/10.1172/JCI29881 117:175-184
    • (2007) J. Clin. Invest. , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 76
    • 84878805816 scopus 로고    scopus 로고
    • Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis
    • Lundberg, A.M., D.F. Ketelhuth, M.E. Johansson, N. Gerdes, S. Liu, M. Yamamoto, S. Akira, and G.K. Hansson. 2013. Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis. Cardiovasc. Res. http://dx.doi.org/10.1093/cvr/cvt033 99:364-373
    • (2013) Cardiovasc. Res. , vol.99 , pp. 364-373
    • Lundberg, A.M.1    Ketelhuth, D.F.2    Johansson, M.E.3    Gerdes, N.4    Liu, S.5    Yamamoto, M.6    Akira, S.7    Hansson, G.K.8
  • 77
    • 80053397336 scopus 로고    scopus 로고
    • Epidemiology of the metabolic syndrome in the USA
    • McCullough, A.J. 2011. Epidemiology of the metabolic syndrome in the USA. J. Dig. Dis. http://dx.doi.org/10.1111/j.1751-2980.2010.00469.x 12:333-340
    • (2011) J. Dig. Dis. , vol.12 , pp. 333-340
    • McCullough, A.J.1
  • 78
    • 3242710174 scopus 로고    scopus 로고
    • Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
    • Michelsen, K.S., M.H. Wong, P.K. Shah, W. Zhang, J. Yano, T.M. Doherty, S. Akira, T.B. Rajavashisth, and M. Arditi. 2004. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc. Natl. Acad. Sci. USA. http://dx.doi.org/10.1073/pnas.0403249101 101:10679-10684
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 10679-10684
    • Michelsen, K.S.1    Wong, M.H.2    Shah, P.K.3    Zhang, W.4    Yano, J.5    Doherty, T.M.6    Akira, S.7    Rajavashisth, T.B.8    Arditi, M.9
  • 79
    • 80054941004 scopus 로고    scopus 로고
    • AIMing at metabolic syndrome-Towards the development of novel therapies for metabolic diseases via apoptosis inhibitor of macrophage (AIM)
    • Miyazaki, T., J. Kurokawa, and S. Arai. 2011. AIMing at metabolic syndrome. -Towards the development of novel therapies for metabolic diseases via apoptosis inhibitor of macrophage (AIM).- Circ. J. http://dx.doi.org/10.1253/circj. CJ-11-0891 75:2522-2531
    • (2011) Circ. J. , vol.75 , pp. 2522-2531
    • Miyazaki, T.1    Kurokawa, J.2    Arai, S.3
  • 80
    • 77955362775 scopus 로고    scopus 로고
    • Chronic inflammation in obesity and the metabolic syndrome
    • Monteiro, R., and I. Azevedo. 2010. Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm. http://dx.doi.org/10.1155/2010/289645 2010:2010
    • (2010) Mediators Inflamm , vol.2010 , pp. 2010
    • Monteiro, R.1    Azevedo, I.2
  • 81
    • 84862777755 scopus 로고    scopus 로고
    • CX3CR1 deficiency does not influence trafficking of adipose tissue macrophages in mice with diet-induced obesity
    • Morris, D.L., K.E. Oatmen, T. Wang, J.L. DelProposto, and C.N. Lumeng. 2012. CX3CR1 deficiency does not influence trafficking of adipose tissue macrophages in mice with diet-induced obesity. Obesity (Silver Spring). http://dx.doi.org/10.1038/oby.2012.7 20:1189-1199
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 1189-1199
    • Morris, D.L.1    Oatmen, K.E.2    Wang, T.3    DelProposto, J.L.4    Lumeng, C.N.5
  • 82
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy, L., P. Tontonoz, J.G. Alvarez, H. Chen, and R.M. Evans. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. http://dx.doi.org/10.1016/S0092-8674(00)81574-3 93:229-240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 83
    • 31044447347 scopus 로고    scopus 로고
    • Inflamed fat: what starts the fire?
    • Neels, J.G., and J.M. Olefsky. 2006. Inflamed fat: what starts the fire? J. Clin. Invest. http://dx.doi.org/10.1172/JCI27280 116:33-35
    • (2006) J. Clin. Invest. , vol.116 , pp. 33-35
    • Neels, J.G.1    Olefsky, J.M.2
  • 84
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNKdependent pathways
    • Nguyen, M.T., S. Favelyukis, A.K. Nguyen, D. Reichart, P.A. Scott, A. Jenn, R. Liu-Bryan, C.K. Glass, J.G. Neels, and J.M. Olefsky. 2007. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNKdependent pathways. J. Biol. Chem. http://dx.doi.org/10.1074/jbc. M706762200 282:35279-35292
    • (2007) J. Biol. Chem , vol.282 , pp. 35279-35292
    • Nguyen, M.T.1    Favelyukis, S.2    Nguyen, A.K.3    Reichart, D.4    Scott, P.A.5    Jenn, A.6    Liu-Bryan, R.7    Glass, C.K.8    Neels, J.G.9    Olefsky, J.M.10
  • 85
    • 77249132284 scopus 로고    scopus 로고
    • Adipose tissue inflammation in obesity and metabolic syndrome
    • Nishimura, S., I. Manabe, and R. Nagai. 2009. Adipose tissue inflammation in obesity and metabolic syndrome. Discov. Med. 8:55-60
    • (2009) Discov. Med. , vol.8 , pp. 55-60
    • Nishimura, S.1    Manabe, I.2    Nagai, R.3
  • 87
    • 79251482742 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
    • Petrasek, J., A. Dolganiuc, T. Csak, B. Nath, I. Hritz, K. Kodys, D. Catalano, E. Kurt-Jones, P. Mandrekar, and G. Szabo. 2011. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology. http://dx.doi.org/10.1002/hep.24059 53:649-660
    • (2011) Hepatology , vol.53 , pp. 649-660
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Nath, B.4    Hritz, I.5    Kodys, K.6    Catalano, D.7    Kurt-Jones, E.8    Mandrekar, P.9    Szabo, G.10
  • 88
    • 25844456730 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
    • Plomgaard, P., K. Bouzakri, R. Krogh-Madsen, B. Mittendorfer, J.R. Zierath, and B.K. Pedersen. 2005. Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes. http://dx.doi.org/10.2337/diabetes.54.10.2939 54:2939-2945
    • (2005) Diabetes , vol.54 , pp. 2939-2945
    • Plomgaard, P.1    Bouzakri, K.2    Krogh-Madsen, R.3    Mittendorfer, B.4    Zierath, J.R.5    Pedersen, B.K.6
  • 90
    • 79952437112 scopus 로고    scopus 로고
    • Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice
    • Prieur, X., C.Y. Mok, V.R. Velagapudi, V. Núñez, L. Fuentes, D. Montaner, K. Ishikawa, A. Camacho, N. Barbarroja, S. O'Rahilly, et al. 2011. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice. Diabetes. http://dx.doi.org/10.2337/db10-0705 60:797-809
    • (2011) Diabetes , vol.60 , pp. 797-809
    • Prieur, X.1    Mok, C.Y.2    Velagapudi, V.R.3    Núñez, V.4    Fuentes, L.5    Montaner, D.6    Ishikawa, K.7    Camacho, A.8    Barbarroja, N.9    O'Rahilly, S.10
  • 91
    • 84872376537 scopus 로고    scopus 로고
    • The LPS2 mutation in TRIF is atheroprotective in hyperlipidemic low density lipoprotein receptor knockout mice
    • Richards, M.R., A.S. Black, D.J. Bonnet, G.D. Barish, C.W. Woo, I. Tabas, L.K. Curtiss, and P.S. Tobias. 2013. The LPS2 mutation in TRIF is atheroprotective in hyperlipidemic low density lipoprotein receptor knockout mice. Innate Immun. http://dx.doi.org/10.1177/1753425912447130 19:20-29
    • (2013) Innate Immun , vol.19 , pp. 20-29
    • Richards, M.R.1    Black, A.S.2    Bonnet, D.J.3    Barish, G.D.4    Woo, C.W.5    Tabas, I.6    Curtiss, L.K.7    Tobias, P.S.8
  • 92
    • 84860530517 scopus 로고    scopus 로고
    • Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation
    • Rios, F.J., M.M. Koga, M. Ferracini, and S. Jancar. 2012. Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation. PLoS ONE. http://dx.doi.org/10.1371/journal.pone.0036632 7:e36632
    • (2012) PLoS ONE , vol.7
    • Rios, F.J.1    Koga, M.M.2    Ferracini, M.3    Jancar, S.4
  • 93
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • Rotter, V., I. Nagaev, and U. Smith. 2003. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J. Biol. Chem. http://dx.doi.org/10.1074/jbc. M301977200 278:45777-45784
    • (2003) J. Biol. Chem. , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 94
  • 95
    • 33847080411 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions
    • Shaposhnik, Z., X. Wang, M. Weinstein, B.J. Bennett, and A.J. Lusis. 2007. Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.0000254673.55431.e6 27:621-627
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 621-627
    • Shaposhnik, Z.1    Wang, X.2    Weinstein, M.3    Bennett, B.J.4    Lusis, A.J.5
  • 96
    • 77951822653 scopus 로고    scopus 로고
    • Dynamic-M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet-induced obesity in mice. Diabetes
    • Shaul, M.E., G. Bennett, K.J. Strissel, A.S. Greenberg, and M.S. Obin. 2010. Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet-induced obesity in mice. Diabetes. http://dx.doi.org/10.2337/db09-1402 59:1171-1181
    • (2010) , vol.59 , pp. 1171-1181
    • Shaul, M.E.1    Bennett, G.2    Strissel, K.J.3    Greenberg, A.S.4    Obin, M.S.5
  • 97
    • 0034604223 scopus 로고    scopus 로고
    • Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice
    • Shi W., M.E. Haberland, M.L. Jien, D.M. Shih, and A.J. Lusis. Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. Circulation. 2000. 102:75-81
    • (2000) Circulation , vol.102 , pp. 75-81
    • Shi, W.1    Haberland, M.E.2    Jien, M.L.3    Shih, D.M.4    Lusis, A.J.5
  • 98
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi, H., M.V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J.S. Flier. 2006. TLR4 links innate immunity and fatty acid-induced insulin resistance. J. Clin. Invest. http://dx.doi.org/10.1172/JCI28898 116:3015-3025
    • (2006) J. Clin. Invest. , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 99
    • 77957089193 scopus 로고    scopus 로고
    • Increased aortic atherosclerotic plaque development in female apolipoprotein E-null mice is associated with elevated thromboxane A2 and decreased prostacyclin production
    • Smith, D.D., X. Tan, O. Tawfik, G. Milne, D.J. Stechschulte, and K.N. Dileepan. 2010. Increased aortic atherosclerotic plaque development in female apolipoprotein E-null mice is associated with elevated thromboxane A2 and decreased prostacyclin production. J. Physiol. Pharmacol. 61:309-316
    • (2010) J. Physiol. Pharmacol. , vol.61 , pp. 309-316
    • Smith, D.D.1    Tan, X.2    Tawfik, O.3    Milne, G.4    Stechschulte, D.J.5    Dileepan, K.N.6
  • 100
    • 0037071851 scopus 로고    scopus 로고
    • Cardiovascular biology: a cholesterol tether
    • Staels, B. 2002. Cardiovascular biology: a cholesterol tether. Nature. http://dx.doi.org/10.1038/417699a 417:699-701
    • (2002) Nature , vol.417 , pp. 699-701
    • Staels, B.1
  • 102
    • 79953295363 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein induces bone morphogenetic protein-2 in coronary artery endothelial cells via Toll-like receptors 2 and 4
    • Su, X., L. Ao, Y. Shi, T.R. Johnson, D.A. Fullerton, and X. Meng. 2011. Oxidized low density lipoprotein induces bone morphogenetic protein-2 in coronary artery endothelial cells via Toll-like receptors 2 and 4. J. Biol. Chem. http://dx.doi.org/10.1074/jbc. M110.214619 286:12213-12220
    • (2011) J. Biol. Chem. , vol.286 , pp. 12213-12220
    • Su, X.1    Ao, L.2    Shi, Y.3    Johnson, T.R.4    Fullerton, D.A.5    Meng, X.6
  • 103
    • 84873814446 scopus 로고    scopus 로고
    • Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs
    • Subramanian, M., E. Thorp, G.K. Hansson, and I. Tabas. 2013. Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs. J. Clin. Invest. http://dx.doi.org/10.1172/JCI64617 123:179-188
    • (2013) J. Clin. Invest. , vol.123 , pp. 179-188
    • Subramanian, M.1    Thorp, E.2    Hansson, G.K.3    Tabas, I.4
  • 104
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha
    • Suganami, T., J. Nishida, and Y. Ogawa. 2005. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.0000183883.72263.13 25: 2062-2068
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 105
    • 33846323706 scopus 로고    scopus 로고
    • Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages
    • Suganami, T., K. Tanimoto-Koyama, J. Nishida, M. Itoh, X. Yuan, S. Mizuarai, H. Kotani, S. Yamaoka, K. Miyake, S. Aoe, et al. 2007. Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.0000251608.09329.9a 27:84-91
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 84-91
    • Suganami, T.1    Tanimoto-Koyama, K.2    Nishida, J.3    Itoh, M.4    Yuan, X.5    Mizuarai, S.6    Kotani, H.7    Yamaoka, S.8    Miyake, K.9    Aoe, S.10
  • 106
    • 79957916782 scopus 로고    scopus 로고
    • Adipose tissue remodeling and obesity
    • Sun, K., C.M. Kusminski, and P.E. Scherer. 2011. Adipose tissue remodeling and obesity. J. Clin. Invest. http://dx.doi.org/10.1172/JCI45887 121:2094-2101
    • (2011) J. Clin. Invest. , vol.121 , pp. 2094-2101
    • Sun, K.1    Kusminski, C.M.2    Scherer, P.E.3
  • 107
    • 0036448929 scopus 로고    scopus 로고
    • MyD88 as a bottle neck in Toll/IL-1 signaling
    • Takeuchi, O., and S. Akira. 2002. MyD88 as a bottle neck in Toll/IL-1 signaling. Curr. Top. Microbiol. Immunol. 270:155-167
    • (2002) Curr. Top. Microbiol. Immunol. , vol.270 , pp. 155-167
    • Takeuchi, O.1    Akira, S.2
  • 110
    • 0029440585 scopus 로고
    • Mechanism of increase in basal lipolysis of enlarged adipocytes in obese animals
    • Tsujita, T., C. Morimoto, and H. Okuda. 1995. Mechanism of increase in basal lipolysis of enlarged adipocytes in obese animals. Obes. Res. http://dx.doi.org/10.1002/j.1550-8528.1995.tb00478.x 3(Suppl 5): 633S-636S
    • (1995) Obes. Res. , vol.3 , Issue.SUPPL. 5
    • Tsujita, T.1    Morimoto, C.2    Okuda, H.3
  • 111
    • 79151484549 scopus 로고    scopus 로고
    • Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppellike factor 2
    • van Tits, L.J., R. Stienstra, P.L. Van Lent, M.G. Netea, L.A. Joosten, and A.F. Stalenhoef. 2011. Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppellike factor 2. Atherosclerosis. http://dx.doi.org/10.1016/j.atherosclerosis.2010.11.018 214:345-349
    • (2011) Atherosclerosis , vol.214 , pp. 345-349
    • van Tits, L.J.1    Stienstra, R.2    Van Lent, P.L.3    Netea, M.G.4    Joosten, L.A.5    Stalenhoef, A.F.6
  • 114
    • 67649406270 scopus 로고    scopus 로고
    • Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis
    • Wajchenberg, B.L., M. Nery, M.R. Cunha, and M.E. Silva. 2009. Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis. Arq. Bras. Endocrinol. Metabol. http://dx.doi.org/10.1590/S0004-27302009000200005 53:145-150
    • (2009) Arq. Bras. Endocrinol. Metabol. , vol.53 , pp. 145-150
    • Wajchenberg, B.L.1    Nery, M.2    Cunha, M.R.3    Silva, M.E.4
  • 115
    • 42049098600 scopus 로고    scopus 로고
    • Heterogeneity of human macrophages in culture and in atherosclerotic plaques
    • Waldo, S.W., Y. Li, C. Buono, B. Zhao, E.M. Billings, J. Chang, and H.S. Kruth. 2008. Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am. J. Pathol. http://dx.doi.org/10.2353/ajpath.2008.070513 172:1112-1126
    • (2008) Am. J. Pathol. , vol.172 , pp. 1112-1126
    • Waldo, S.W.1    Li, Y.2    Buono, C.3    Zhao, B.4    Billings, E.M.5    Chang, J.6    Kruth, H.S.7
  • 118
    • 80155214124 scopus 로고    scopus 로고
    • Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation
    • Wolfs, I.M., M.M. Donners, and M.P. de Winther. 2011. Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation. Thromb. Haemost. http://dx.doi.org/10.1160/TH11-05-0320 106:763-771
    • (2011) Thromb. Haemost. , vol.106 , pp. 763-771
    • Wolfs, I.M.1    Donners, M.M.2    De Winther, M.P.3
  • 120
    • 34249017742 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification
    • Yao, J., T.W. Kim, J. Qin, Z. Jiang, Y. Qian, H. Xiao, Y. Lu, W. Qian, M.F. Gulen, N. Sizemore, et al. 2007. Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification. J. Biol. Chem. http://dx.doi.org/10.1074/jbc. M609039200 282:6075-6089
    • (2007) J. Biol. Chem. , vol.282 , pp. 6075-6089
    • Yao, J.1    Kim, T.W.2    Qin, J.3    Jiang, Z.4    Qian, Y.5    Xiao, H.6    Lu, Y.7    Qian, W.8    Gulen, M.F.9    Sizemore, N.10
  • 121
    • 34548477639 scopus 로고    scopus 로고
    • Adipose tissue macrophages
    • Zeyda, M., and T.M. Stulnig. 2007. Adipose tissue macrophages. Immunol. Lett. http://dx.doi.org/10.1016/j.imlet.2007.07.003 112:61-67
    • (2007) Immunol. Lett. , vol.112 , pp. 61-67
    • Zeyda, M.1    Stulnig, T.M.2
  • 122
    • 78650176649 scopus 로고    scopus 로고
    • Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression
    • Zeyda, M., K. Gollinger, E. Kriehuber, F.W. Kiefer, A. Neuhofer, and T.M. Stulnig. 2010. Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression. Int J Obes (Lond). http://dx.doi.org/10.1038/ijo.2010.103 34:1684-1694
    • (2010) Int J Obes (Lond) , vol.34 , pp. 1684-1694
    • Zeyda, M.1    Gollinger, K.2    Kriehuber, E.3    Kiefer, F.W.4    Neuhofer, A.5    Stulnig, T.M.6
  • 124
    • 70350455635 scopus 로고    scopus 로고
    • GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions
    • Zhu, S.N., M. Chen, J. Jongstra-Bilen, and M.I. Cybulsky. 2009. GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions. J. Exp. Med. http://dx.doi.org/10.1084/jem.20090866 206:2141-2149
    • (2009) J. Exp. Med. , vol.206 , pp. 2141-2149
    • Zhu, S.N.1    Chen, M.2    Jongstra-Bilen, J.3    Cybulsky, M.I.4
  • 125
    • 20144365612 scopus 로고    scopus 로고
    • Elevated serum Creactive protein levels and advanced atherosclerosis in youth
    • Pathobiological Determinants of Atherosclerosis in Youth Research Group
    • Zieske, A.W., R.P. Tracy, C.A. McMahan, E.E. Herderick, S. Homma, G.T. Malcom, H.C. McGill Jr., and J.P. Strong; Pathobiological Determinants of Atherosclerosis in Youth Research Group. 2005. Elevated serum Creactive protein levels and advanced atherosclerosis in youth. Arterioscler. Thromb. Vasc. Biol. http://dx.doi.org/10.1161/01.ATV.0000164625.93129.64 25:1237-1243
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 1237-1243
    • Zieske, A.W.1    Tracy, R.P.2    McMahan, C.A.3    Herderick, E.E.4    Homma, S.5    Malcom, G.T.6    McGill Jr., H.C.7    Strong, J.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.