Comparison of hepatic oxidative DNA damage in patients with chronic hepatitis B and C

Journal of Viral Hepatitis

Volumn 15, Issue 7, 2008, Pages 498-507

  Fujita, N ^a   Sugimoto, R ^a   Ma, N ^a   Tanaka, H ^a   Iwasa, M ^a   Kobayashi, Y ^a   Kawanishi, S ^b   Watanabe, S ^c   Kaito, M ^a   Takei, Y ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c MIE UNIVERSITY   (Japan)

Author keywords

Alanine aminotransferase aspartate aminotrasferase; hepatitis B virus; Hepatitis C virus; Hepatocellular carcinoma; Iron; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FERRITIN; HEPCIDIN;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; FEMALE; FERRITIN BLOOD LEVEL; HEPATITIS B; HEPATITIS C; HUMAN; IMMUNOHISTOCHEMISTRY; IRON STORAGE; LIVER BIOPSY; LIVER CARCINOGENESIS; LIVER CELL; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; DEOXYGUANOSINE; DNA DAMAGE; FEMALE; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; IRON OVERLOAD; LIVER; MALE; MIDDLE AGED; OXIDATIVE STRESS;

EID: 44849129329     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2008.00972.x     Document Type: Article

References (37)

1. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007 39 : 44 84.
2. Shigenaga M, Gimeno CJ, Ames BN. Urinary 8-hydroxy-2'-deoxyguanosine as a biomarker of in vivo oxidative DNA damage. Proc Natl Acad Sci USA 1989 86 : 9697 9701.
3. Kasai H. Analysis of a form of oxidative DNA damage 8-hydroxy-2'- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res 1997 387 : 147 163.
4. Kuchino Y, Mori F, Kasai H et al. Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Nature 1987 327 : 77 79.
5. El-Serag HB. Hepatocellular carcinoma and hepatitis C in the United States. Hepatology 2002 36 (Suppl. 1 74 83.
6. Kiyosawa K, Tanaka E. Characteristics of hepatocellular carcinoma in Japan. Oncology 2002 62 (Suppl. 1 5 7.
7. Stroffolini T, Chiaramonte M, Tiribelli C et al. Hepatitis C virus infection, HBsAg carrier state and hepatocellular carcinoma: relative risk and population attributable risk from a case-control study in Italy. J Hepatol 1992 16 : 360 363.
8. Ikeda K, Saitoh S, Koida I et al. A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 1993 18 : 47 53.
9. Paradis V, Mathurin P, Kollinger M et al. In situ detection of lipid peroxidation of chronic hepatitis C: correlation with pathological features. J Clin Pathol 1997 50 : 401 406.
10. Larrea E, Beloqui O, Munoz-Navas MA, Civeira MP, Prieto J. Superoxide dismutase in patients with chronic hepatitis C virus infection. Free Radic Biol Med 1998 24 : 1235 1241.
11. Marotta F, Yoshida C, Barreto R, Naito Y, Packer L. Oxidative- inflammatory damage in cirrhosis: effect of vitamin E and a fermented papaya preparation. J Gastroenterol Hepatol 2007 22 : 697 703.
12. Barbaro G, Di Lorenzo G, Ribersani M et al. Serum and hepatic glutathione concentrations in chronic hepatitis C patients related to hepatitis C virus genotype. J Hepatol 1999 30 : 774 782.
13. Mahmood S, Yamada G, Niiyama G et al. Effect of vitamin E on serum aminotransferase and thioredoxin levels in patients with viral hepatitis C. Free Radic Res 2003 37 : 781 785.
14. Shafritz DA, Kew MC. Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. New Engl J Med 1981 305 : 1067 1073.
15. Natoli G, Avantaggiati ML, Chirillo P et al. Ras- and Raf-dependent activation of c-jun transcriptional activity by the hepatitis B virus transactivator pX. Oncogene 1994 9 : 2837 2843.
16. Huang SN, Chisari FV. Strong, sustained hepatocellular proliferation precedes hepatocarcingenesis in hepatitis B surface antigen transgenic mice. Hepatology 1995 21 : 620 626.
17. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994 19 : 1513 1520.
18. Deugnier YM, Loreal O, Turlin B et al. Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations. Gastroenterology 1992 102 : 2050 2059.
19. Deugnier YM, Turlin B, Powell LW et al. Differentiation between heterozygotes and homozygotes in genetic hemochromatosis by means of a histological hepatic iron index: a study of 192 cases. Hepatology 1993 17 : 30 34.
20. Piperno A, Vergani A, Malosio I et al. Hepatic iron overload in patients with chronic viral hepatitis: role of HFE gene mutations. Hepatology 1998 28 : 1105 1109.
21. Silvia IS, Perez RM, Oliveira PV et al. Iron overload in patients with chronic hepatitis C virus infection: clinical and histological study. J Gastroentrol Hepatol 2005 20 : 243 248.
22. Horiike S, Kawanishi S, Kaito M et al. Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. J Hepatol 2005 43 : 403 410.
23. Takeo M, Kobayashi Y, Fujita N et al. Upregulation of transferrin receptor 2 and ferroportin 1 mRNA in the liver of patients with chronic hepatitis C. J Gastroenterol Hepatol 2005 20 : 562 569.
24. Fujita N, Sugimoto R, Takeo M et al. Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C. Mol Med 2007 13 : 97 104.
25. Pigeon C, Ilyin G, Courselaud B et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001 276 : 7811 7819.
26. Frazer DM, Wilkins SJ, Becker EM et al. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 2002 123 : 835 844.
27. Konishi M, Iwasa M, Araki J et al. Increased lipid peroxidation in patients with non-alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8-isoprostane. J Gastroenterol Hepatol 2006 21 : 1821 1825.
28. Shimoda R, Nagashima M, Sakamoto M et al. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res 1994 54 : 3171 3172.
29. Kato J, Kobune M, Nakamura T et al. Normalization of elevated hepatic 8-hydroxy-2'-deoxyguanosine levels in chronic hepatitis C patients by phlebotomy and low iron diet. Cancer Res 2001 61 : 8697 8702.
30. Escodd. Comparative analysis of baseline 8-oxo-7, 8-dihydroguanosine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis 2002 23 : 2129 2133.
31. Sumida Y, Nakashima T, Yoh T et al. Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection. J Hepatol 2000 33 : 616 622.
32. Kubo S, Nishiguchi S, Shuto T et al. Effects of continuous hepatitis with persistent hepatitis C viremia on outcome after resection of hepatocellular carcinoma. Jpn J Cancer Res 1999 90 : 162 170.
33. Nishikawa M, Nishiguchi S, Kioka K, Tomori A, Inoue M. Interferon reduces somatic mutation of mitochondrial DNA in liver tissues from chronic viral hepatitis patients. J Viral Hepat 2005 12 : 494 498.
34. Sebastiani G, Vario A, Ferrari R, Pistis F, Noventa F, Alberti A. Hepatic iron, liver steatosis and viral genotypes in patients with chronic hepatitis C. J Viral Hepat 2005 13 : 199 205.
35. Prieto J, Barry M, Sherlock S. Serum ferritin in patients with iron overload and with acute and chronic liver diseases. Gastroenterology 1975 68 : 525 533.
36. Majano PL, Monzon CG, Cabrera LC et al. Inducible nitric oxide synthase expression in chronic viral hepatitis: evidence for a virus-induced gene upregulation. J Clin Invest 1998 101 : 1343 1352.
37. Wink DA, Kasprzak KS, Maragos CM et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 1991 254 : 1001 1003.