Hepatitis B virus x protein inhibits nucleotide excision repair

International Journal of Cancer

Volumn 80, Issue 6, 1999, Pages 875-879

  Jia, Libin ^a   Wang, Xin Wei ^a   Harris, Curtis C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HELICASE; HEPATITIS B VIRUS X PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; CANCER RISK; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; EXCISION REPAIR; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; MUTATION RATE; NONHUMAN; PHOTOSENSITIVITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; TRANSCRIPTION REGULATION; ULTRAVIOLET C RADIATION; VIRUS CARCINOGENESIS; VIRUS CELL INTERACTION;

EID: 0033559939     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0215(19990315)80:6<875::aid-ijc13>3.0.co;2-z     Document Type: Article

References (21)

1. BEASLEY, R.P., HWANG, L.Y., LIN, C.C. and CHIEN, C.S., Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22.707 men in Taiwan. Lancet, 2, 1129-1133 (1981).
2. BECKER, S.A., LEE, T.H., BUTEL, J.S. and SLAGLE, B.L., Hepatitis B virus X protein interferes with cellular DNA repair. J Virol., 72, 266-272 (1998).
3. BENN, J. and SCHNEIDER, R.J., Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade. Proc. nat. Acad. Sci. (Wash.), 91, 10350-10354 (1994).
4. BENN, J. and SCHNEIDER, R.J., Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls. Proc. nat. Acad. Sci (Wash.), 92, 11215-11219 (1995).
5. CAPOVILLA, A., CARMONA, S. and ARBUTHNOT, P., Hepatitis B virus X-protein binds damaged DNA and sensitizes liver cells to ultraviolet irradiation. Biochem. biophys. Res Comm., 232, 255-260 (1997).
6. ELMORE, L.W., HANCOCK, A.R., CHANG, S.F., WANG, X.W., CHANG, S., CALLAHAN, C.P., GELLER, D.A., WILL, H. and HARRIS, C.C., Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc. nat. Acad. Sci. (Wash.), 94, 14707-14712 (1997).
7. ELMORE, L.W. and HARRIS, C.C., Hepatocellular carcinoma. In: B. Vogelstein and K.W. Kinzler (eds.), The genetic basis of human cancer, pp. 682-689, McGraw-Hill, New York (1998).
8. FEITELSON, M.A. and DUAN, L.X., Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. Amer. J Pathol., 150, 1141-1157 (1997).
9. FEITELSON, M.A., ZHU, M., DUAN, L.X. and LONDON, W.T., Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Oncogene, 8, 1109-1117 (1993).
10. HARRIS, C.C., WESTON, A., WILLEY, J.C., TRIVERS, G.E. and MANN, D.L., Biochemical and molecular epidemiology of human cancer: indicators of carcinogen exposure, DNA damage, and genetic predisposition. Environ. Hlth. Perspect., 75, 109-119 (1987).
11. JIA, L., WANG, X.W., SUN, Z. and HARRIS, C.C., Interactive effects of p53 tumor suppressor gene and hepatitis B virus in hepatocellular carcinogenesis. In: E. Tahara (ed.), Molecular pathology of gastroenterological cancer: application to clinical practice, pp. 209-218, Springer-Verlag, Tokyo (1997).
12. LEE, T.H., ELLEDGE, S.J. and BUTEL, J.S., Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J. Virol., 69, 1107-1114 (1995).
13. LEVEILLARD, T., ANDERA, L., BISSONNETTE, N., SCHAEFFER, L., BRACCO, L., EGLY, J.M. and WASYLYK, B., Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J., 15, 1615-1624 (1996).
14. QADRI, I., CONAWAY, J.W., CONAWAY, R.C., SCHAACK, J. and SIDDIQUI, A., Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH. Proc. nat. Acad. Sci (Wash.), 93, 10578-10583 (1996).
15. SMITH, M.L., CHEN, I.T., ZHAN, Q., O'CONNOR, P.M. and FORNACE, A.J., JR., Involvement of the p53 tumor suppressor in repair of UV-type DNA damage. Oncogene, 10, 1053-1059 (1995).
16. SONG, B.J., GELBOIN, H.V., PARK, S.S., TSOKOS, G.C. and FRIEDMAN, F.K., Monoclonal antibody-directed radioimmunoassay detects cytochrome P-450 in human placenta and lymphocytes. Science, 228, 490-492 (1985).
17. TAKADA, S., KANENIWA, N., TSUCHIDA, N. and KOIKE, K., Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells. Oncogene, 15, 1895-1901 (1997).
18. UEDA, H., ULLRICH, S.J., GANGEMI, J.D., KAPPEL, C.A., NGO, L., FEITELSON, M.A. and JAY, G., Functional inactivation but not structural mutation of p53 causes liver cancer. Nature (Genet.), 9, 41-47 (1995).
19. WANG, X.W., FORRESTER, K., YEH, H., FEITELSON, M.A., GU, J.R. and HARRIS, C.C., Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. nat. Acad. Sci. (Wash.), 91, 2230-2234 (1994).
20. WANG, X.W., GIBSON, M.K., VERMEULEN, W., YEH, H., FORRESTER, K., STURZBECHER, H.W., HOEIJMAKERS, J.H.J. and HARRIS, C.C., Abrogation of p53-induced apoptosis by the hepatitis B virus X gene. Cancer Res., 55, 6012-6016 (1995a).
21. WANG, X.W. and 14 OTHERS, p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature (Genet.), 10, 188-195 (1995b).