-
1
-
-
33646867426
-
Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions
-
Jaeschke H. Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions. Am. J. Physiol. Gastrointest. Liver Physiol. 2006; 290: G1083-G1088.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
-
-
Jaeschke, H.1
-
2
-
-
0025687478
-
Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo
-
Jaeschke H, Farhood A, Smith CW. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB J. 1990; 4: 3355-9.
-
(1990)
FASEB J.
, vol.4
, pp. 3355-3359
-
-
Jaeschke, H.1
Farhood, A.2
Smith, C.W.3
-
3
-
-
0027156112
-
Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver
-
Jaeschke H, Farhood A, Bautista AP, Spolarics Z, Spitzer JJ, Smith CW. Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver. Hepatology. 1993; 17: 915-23.
-
(1993)
Hepatology.
, vol.17
, pp. 915-923
-
-
Jaeschke, H.1
Farhood, A.2
Bautista, A.P.3
Spolarics, Z.4
Spitzer, J.J.5
Smith, C.W.6
-
4
-
-
0026341918
-
Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism
-
Jaeschke H, Farhood A, Smith CW. Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am. J. Physiol. 1991; 261: G1051-G1056.
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Jaeschke, H.1
Farhood, A.2
Smith, C.W.3
-
5
-
-
0042766884
-
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice
-
Gujral JS, Farhood A, Bajt ML, Jaeschke H. Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology. 2003; 38: 355-63.
-
(2003)
Hepatology.
, vol.38
, pp. 355-363
-
-
Gujral, J.S.1
Farhood, A.2
Bajt, M.L.3
Jaeschke, H.4
-
6
-
-
0036017173
-
Neutrophilic infiltration in alcoholic hepatitis
-
Bautista AP. Neutrophilic infiltration in alcoholic hepatitis. Alcohol. 2002; 27: 17-21.
-
(2002)
Alcohol.
, vol.27
, pp. 17-21
-
-
Bautista, A.P.1
-
7
-
-
33845681113
-
Role of neutrophils in a mouse model of halothane-induced liver injury
-
You Q, Cheng L, Reilly TP, Wegmann D, Ju C. Role of neutrophils in a mouse model of halothane-induced liver injury. Hepatology. 2006; 44: 1421-31.
-
(2006)
Hepatology.
, vol.44
, pp. 1421-1431
-
-
You, Q.1
Cheng, L.2
Reilly, T.P.3
Wegmann, D.4
Ju, C.5
-
8
-
-
0024427459
-
Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock
-
Vedder NB, Fouty BW, Winn RK, Harlan JM, Rice CL. Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock. Surgery. 1989; 106: 509-16.
-
(1989)
Surgery.
, vol.106
, pp. 509-516
-
-
Vedder, N.B.1
Fouty, B.W.2
Winn, R.K.3
Harlan, J.M.4
Rice, C.L.5
-
9
-
-
0025756580
-
Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver
-
Jaeschke H, Farhood A. Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver. Am. J. Physiol. 1991; 260: G355-G362.
-
(1991)
Am. J. Physiol.
, vol.260
-
-
Jaeschke, H.1
Farhood, A.2
-
10
-
-
0029204907
-
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia
-
Liu P, McGuire GM, Fisher MA, Farhood A, Smith CW, Jaeschke H. Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. Shock. 1995; 3: 56-62.
-
(1995)
Shock.
, vol.3
, pp. 56-62
-
-
Liu, P.1
McGuire, G.M.2
Fisher, M.A.3
Farhood, A.4
Smith, C.W.5
Jaeschke, H.6
-
11
-
-
0026749890
-
Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo
-
Jaeschke H. Enhanced sinusoidal glutathione efflux during endotoxin-induced oxidant stress in vivo. Am. J. Physiol. 1992; 263: G60-G68.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Jaeschke, H.1
-
12
-
-
0023805308
-
Modulation of hepatotoxicity by macrophages in the liver
-
Shiratori Y, Kawase T, Shiina S et al. Modulation of hepatotoxicity by macrophages in the liver. Hepatology. 1988; 8: 815-21.
-
(1988)
Hepatology.
, vol.8
, pp. 815-821
-
-
Shiratori, Y.1
Kawase, T.2
Shiina, S.3
-
13
-
-
0022407632
-
Oxygen-derived free radicals promote hepatic injury in the rat
-
Arthur MJ, Bentley IS, Tanner AR, Saunders PK, Millward-Sadler GH, Wright R. Oxygen-derived free radicals promote hepatic injury in the rat. Gastroenterology. 1985; 89: 1114-22.
-
(1985)
Gastroenterology.
, vol.89
, pp. 1114-1122
-
-
Arthur, M.J.1
Bentley, I.S.2
Tanner, A.R.3
Saunders, P.K.4
Millward-Sadler, G.H.5
Wright, R.6
-
14
-
-
0037229864
-
Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning
-
Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am. J. Physiol. Gastrointest. Liver Physiol. 2003; 284: G15-G26.
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.284
-
-
Jaeschke, H.1
-
15
-
-
0024343745
-
Reperfusion injury to endothelial cells following cold ischemic storage of rat livers
-
Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Reperfusion injury to endothelial cells following cold ischemic storage of rat livers. Hepatology. 1989; 10: 292-9.
-
(1989)
Hepatology.
, vol.10
, pp. 292-299
-
-
Caldwell-Kenkel, J.C.1
Currin, R.T.2
Tanaka, Y.3
Thurman, R.G.4
Lemasters, J.J.5
-
16
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002; 418: 191-5.
-
(2002)
Nature.
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
17
-
-
33845951211
-
DAMPs, PAMPs and alarmins: all we need to know about danger
-
Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 2007; 81: 1-5.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
18
-
-
70149084792
-
HMGB1 loves company
-
Bianchi ME. HMGB1 loves company. J. Leukoc. Biol. 2009; 86: 573-6.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 573-576
-
-
Bianchi, M.E.1
-
20
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
Tsung A, Sahai R, Tanaka H et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J. Exp. Med. 2005; 201: 1135-43.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
-
21
-
-
34248228729
-
Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling
-
Fan J, Li Y, Levy RM et al. Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling. J. Immunol. 2007; 178: 6573-80.
-
(2007)
J. Immunol.
, vol.178
, pp. 6573-6580
-
-
Fan, J.1
Li, Y.2
Levy, R.M.3
-
22
-
-
10344264453
-
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway
-
Zhai Y, Shen XD, O'Connell R et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J. Immunol. 2004; 173: 7115-9.
-
(2004)
J. Immunol.
, vol.173
, pp. 7115-7119
-
-
Zhai, Y.1
Shen, X.D.2
O'Connell, R.3
-
23
-
-
75449096565
-
Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury
-
Bamboat ZM, Balachandran VP, Ocuin LM, Obaid H, Plitas G, DeMatteo RP. Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury. Hepatology. 2010; 51: 621-32.
-
(2010)
Hepatology.
, vol.51
, pp. 621-632
-
-
Bamboat, Z.M.1
Balachandran, V.P.2
Ocuin, L.M.3
Obaid, H.4
Plitas, G.5
DeMatteo, R.P.6
-
24
-
-
0027168520
-
Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia
-
Jaeschke H, Farhood A, Bautista AP, Spolarics Z, Spitzer JJ. Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia. Am. J. Physiol. 1993; 264: G801-G809.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Jaeschke, H.1
Farhood, A.2
Bautista, A.P.3
Spolarics, Z.4
Spitzer, J.J.5
-
26
-
-
78349236196
-
Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice
-
Williams CD, Bajt ML, Farhood A, Jaeschke H. Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice. Liver Int. 2010; 30: 1280-92.
-
(2010)
Liver Int.
, vol.30
, pp. 1280-1292
-
-
Williams, C.D.1
Bajt, M.L.2
Farhood, A.3
Jaeschke, H.4
-
27
-
-
0025330755
-
Superoxide anion generation in the liver during the early stage of endotoxemia in rats
-
Bautista AP, Mészáros K, Bojta J, Spitzer JJ. Superoxide anion generation in the liver during the early stage of endotoxemia in rats. J. Leukoc. Biol. 1990; 48: 123-8.
-
(1990)
J. Leukoc. Biol.
, vol.48
, pp. 123-128
-
-
Bautista, A.P.1
Mészáros, K.2
Bojta, J.3
Spitzer, J.J.4
-
28
-
-
0031008369
-
Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury
-
Chosay JG, Essani NA, Dunn CJ, Jaeschke H. Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury. Am. J. Physiol. 1997; 272: G1195-G1200.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Chosay, J.G.1
Essani, N.A.2
Dunn, C.J.3
Jaeschke, H.4
-
29
-
-
0032055225
-
Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosisand neutrophil-mediated necrosis in a murine endotoxin shock model
-
Jaeschke H, Fisher MA, Lawson JA, Simmons CA, Farhood A, Jones DA. Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosisand neutrophil-mediated necrosis in a murine endotoxin shock model. J. Immunol. 1998; 160: 3480-6.
-
(1998)
J. Immunol.
, vol.160
, pp. 3480-3486
-
-
Jaeschke, H.1
Fisher, M.A.2
Lawson, J.A.3
Simmons, C.A.4
Farhood, A.5
Jones, D.A.6
-
30
-
-
0032987412
-
Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress
-
Jaeschke H, Ho YS, Fisher MA, Lawson JA, Farhood A. Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress. Hepatology. 1999; 29: 443-50.
-
(1999)
Hepatology.
, vol.29
, pp. 443-450
-
-
Jaeschke, H.1
Ho, Y.S.2
Fisher, M.A.3
Lawson, J.A.4
Farhood, A.5
-
32
-
-
1342344120
-
Functional importance of ICAM-1 in the mechanism of neutrophil-induced liver injury in bile duct-ligated mice
-
Gujral JS, Liu J, Farhood A, Hinson JA, Jaeschke H. Functional importance of ICAM-1 in the mechanism of neutrophil-induced liver injury in bile duct-ligated mice. Am. J. Physiol. Gastrointest. Liver Physiol. 2004; 286: G499-G507.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.286
-
-
Gujral, J.S.1
Liu, J.2
Farhood, A.3
Hinson, J.A.4
Jaeschke, H.5
-
33
-
-
0032869839
-
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas
-
Miyoshi H, Rust C, Roberts PJ, Burgart LJ, Gores GJ. Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology. 1999; 117: 669-77.
-
(1999)
Gastroenterology.
, vol.117
, pp. 669-677
-
-
Miyoshi, H.1
Rust, C.2
Roberts, P.J.3
Burgart, L.J.4
Gores, G.J.5
-
34
-
-
78650793157
-
Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis
-
; DOI: 10.1066/j.ajpath.2010.11.026. in press.
-
Allen K, Jaeschke H, Copple BL. Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. Am. J. Pathol. 2011; DOI: 10.1066/j.ajpath.2010.11.026. in press.
-
(2011)
Am. J. Pathol.
-
-
Allen, K.1
Jaeschke, H.2
Copple, B.L.3
-
35
-
-
0023710390
-
Oxidant stress during reperfusion of ischemic liver: no evidence for a role of xanthine oxidase
-
Metzger J, Dore SP, Lauterburg BH. Oxidant stress during reperfusion of ischemic liver: no evidence for a role of xanthine oxidase. Hepatology. 1988; 8: 580-4.
-
(1988)
Hepatology.
, vol.8
, pp. 580-584
-
-
Metzger, J.1
Dore, S.P.2
Lauterburg, B.H.3
-
36
-
-
0026310875
-
Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia
-
Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ. Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia. Free Radic. Res. Commun. 1991; 15: 277-84.
-
(1991)
Free Radic. Res. Commun.
, vol.15
, pp. 277-284
-
-
Jaeschke, H.1
Bautista, A.P.2
Spolarics, Z.3
Spitzer, J.J.4
-
37
-
-
0028054313
-
Beneficial effects of extracellular glutathione against endotoxin-induced liver injury during ischemia and reperfusion
-
Liu P, Fisher MA, Farhood A, Smith CW, Jaeschke H. Beneficial effects of extracellular glutathione against endotoxin-induced liver injury during ischemia and reperfusion. Circ. Shock. 1994; 43: 64-70.
-
(1994)
Circ. Shock.
, vol.43
, pp. 64-70
-
-
Liu, P.1
Fisher, M.A.2
Farhood, A.3
Smith, C.W.4
Jaeschke, H.5
-
38
-
-
0036971906
-
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation
-
Bilzer M, Baron A, Schauer R, Steib C, Ebensberger S, Gerbes AL. Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation. Digestion. 2002; 66: 49-57.
-
(2002)
Digestion.
, vol.66
, pp. 49-57
-
-
Bilzer, M.1
Baron, A.2
Schauer, R.3
Steib, C.4
Ebensberger, S.5
Gerbes, A.L.6
-
39
-
-
0026713741
-
Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats
-
Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ. Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats. J. Leukoc. Biol. 1992; 52: 377-82.
-
(1992)
J. Leukoc. Biol.
, vol.52
, pp. 377-382
-
-
Jaeschke, H.1
Bautista, A.P.2
Spolarics, Z.3
Spitzer, J.J.4
-
40
-
-
25444519723
-
Generation of hypochlorite-modified proteins by neutrophils during ischemia-reperfusion injury in rat liver: attenuation by ischemic preconditioning
-
Hasegawa T, Malle E, Farhood A, Jaeschke H. Generation of hypochlorite-modified proteins by neutrophils during ischemia-reperfusion injury in rat liver: attenuation by ischemic preconditioning. Am. J. Physiol. Gastrointest. Liver Physiol. 2005; 289: G760-G767.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Hasegawa, T.1
Malle, E.2
Farhood, A.3
Jaeschke, H.4
-
41
-
-
1842329163
-
Mechanisms of neutrophil-induced parenchymal cell injury
-
Jaeschke H, Smith CW. Mechanisms of neutrophil-induced parenchymal cell injury. J. Leukoc. Biol. 1997; 61: 647-53.
-
(1997)
J. Leukoc. Biol.
, vol.61
, pp. 647-653
-
-
Jaeschke, H.1
Smith, C.W.2
-
42
-
-
0025219115
-
Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils
-
Shappell SB, Toman C, Anderson DC, Taylor AA, Entman ML, Smith CW. Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils. J. Immunol. 1990; 144: 2702-11.
-
(1990)
J. Immunol.
, vol.144
, pp. 2702-2711
-
-
Shappell, S.B.1
Toman, C.2
Anderson, D.C.3
Taylor, A.A.4
Entman, M.L.5
Smith, C.W.6
-
43
-
-
0033860297
-
Reactive oxygen and mechanisms of inflammatory liver injury
-
Jaeschke H. Reactive oxygen and mechanisms of inflammatory liver injury. J. Gastroenterol. Hepatol. 2000; 15: 718-24.
-
(2000)
J. Gastroenterol. Hepatol.
, vol.15
, pp. 718-724
-
-
Jaeschke, H.1
-
44
-
-
0023882573
-
In vitro toxicity of polymorphonuclear neutrophils to rat hepatocytes: evidence for a proteinase-mediated mechanism
-
Mavier P, Preaux AM, Guigui B, Lescs MC, Zafrani ES, Dhumeaux D. In vitro toxicity of polymorphonuclear neutrophils to rat hepatocytes: evidence for a proteinase-mediated mechanism. Hepatology. 1988; 8: 254-8.
-
(1988)
Hepatology.
, vol.8
, pp. 254-258
-
-
Mavier, P.1
Preaux, A.M.2
Guigui, B.3
Lescs, M.C.4
Zafrani, E.S.5
Dhumeaux, D.6
-
45
-
-
0030803161
-
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation
-
Hazen SL, Crowley JR, Mueller DM, Heinecke JW. Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation. Free Radic. Biol. Med. 1997; 23: 909-16.
-
(1997)
Free Radic. Biol. Med.
, vol.23
, pp. 909-916
-
-
Hazen, S.L.1
Crowley, J.R.2
Mueller, D.M.3
Heinecke, J.W.4
-
46
-
-
0038452749
-
Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide
-
Lehnert M, Arteel GE, Smutney OM et al. Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock. 2003; 19: 345-51.
-
(2003)
Shock.
, vol.19
, pp. 345-351
-
-
Lehnert, M.1
Arteel, G.E.2
Smutney, O.M.3
-
47
-
-
0037309542
-
Induction of cellular resistance against Kupffer cell-derived oxidant stress: a novel concept of hepatoprotection by ischemic preconditioning
-
Schauer RJ, Gerbes AL, Vonier D, op den Winkel M, Fraunberger P, Bilzer M. Induction of cellular resistance against Kupffer cell-derived oxidant stress: a novel concept of hepatoprotection by ischemic preconditioning. Hepatology. 2003; 37: 286-95.
-
(2003)
Hepatology.
, vol.37
, pp. 286-295
-
-
Schauer, R.J.1
Gerbes, A.L.2
Vonier, D.3
op den Winkel, M.4
Fraunberger, P.5
Bilzer, M.6
-
48
-
-
16244397365
-
Neutrophil serine proteases: potential key regulators of cell signalling during inflammation
-
Wiedow O, Meyer-Hoffert U. Neutrophil serine proteases: potential key regulators of cell signalling during inflammation. J. Intern. Med. 2005; 257: 319-28.
-
(2005)
J. Intern. Med.
, vol.257
, pp. 319-328
-
-
Wiedow, O.1
Meyer-Hoffert, U.2
-
49
-
-
77951817301
-
The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury
-
Uchida Y, Freitas MC, Zhao D, Busuttil RW, Kupiec-Weglinski JW. The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury. Transplantation. 2010; 89: 1050-6.
-
(2010)
Transplantation.
, vol.89
, pp. 1050-1056
-
-
Uchida, Y.1
Freitas, M.C.2
Zhao, D.3
Busuttil, R.W.4
Kupiec-Weglinski, J.W.5
-
50
-
-
0024602827
-
Tissue destruction by neutrophils
-
Weiss SJ. Tissue destruction by neutrophils. N. Engl. J. Med. 1989; 320: 365-76.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 365-376
-
-
Weiss, S.J.1
-
51
-
-
85012844007
-
Comprehensive Toxicology
-
In: McQueen CA, ed., Oxford: Academic Press,
-
Jaeschke H. Antioxidant Defense Mechanisms. In: McQueen CA, ed. Comprehensive Toxicology. Vol. 9, Oxford: Academic Press, 2010; 319-37.
-
(2010)
Antioxidant Defense Mechanisms
, vol.9
, pp. 319-337
-
-
Jaeschke, H.1
-
52
-
-
0019518322
-
Drug-induced lipid peroxidation in mice-I. Modulation by monooxygenase activity, glutathione and selenium status
-
Wendel A, Feuerstein S. Drug-induced lipid peroxidation in mice-I. Modulation by monooxygenase activity, glutathione and selenium status. Biochem. Pharmacol. 1981; 30: 2513-20.
-
(1981)
Biochem. Pharmacol.
, vol.30
, pp. 2513-2520
-
-
Wendel, A.1
Feuerstein, S.2
-
53
-
-
77956919580
-
The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes
-
Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes. Toxicol. Sci. 2010; 117: 515-23.
-
(2010)
Toxicol. Sci.
, vol.117
, pp. 515-523
-
-
Yan, H.M.1
Ramachandran, A.2
Bajt, M.L.3
Lemasters, J.J.4
Jaeschke, H.5
-
54
-
-
0037430971
-
Oxidative stress in cell culture: an under-appreciated problem?
-
Halliwell B. Oxidative stress in cell culture: an under-appreciated problem? FEBS Lett. 2003; 540: 3-6.
-
(2003)
FEBS Lett.
, vol.540
, pp. 3-6
-
-
Halliwell, B.1
-
55
-
-
0028225261
-
Lipid peroxidation as molecular mechanism of liver cell injury during reperfusion after ischemia
-
Mathews WR, Guido DM, Fisher MA, Jaeschke H. Lipid peroxidation as molecular mechanism of liver cell injury during reperfusion after ischemia. Free Radic. Biol. Med. 1994; 16: 763-70.
-
(1994)
Free Radic. Biol. Med.
, vol.16
, pp. 763-770
-
-
Mathews, W.R.1
Guido, D.M.2
Fisher, M.A.3
Jaeschke, H.4
-
56
-
-
0242363202
-
Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice
-
Knight TR, Fariss MW, Farhood A, Jaeschke H. Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice. Toxicol. Sci. 2003; 76: 229-36.
-
(2003)
Toxicol. Sci.
, vol.76
, pp. 229-236
-
-
Knight, T.R.1
Fariss, M.W.2
Farhood, A.3
Jaeschke, H.4
-
57
-
-
34249789027
-
Regulation of hepatocyte apoptosis by oxidative stress
-
(Suppl.
-
Singh R, Czaja MJ. Regulation of hepatocyte apoptosis by oxidative stress. J. Gastroenterol. Hepatol. 2007; 22 (Suppl. 1): S45-S48.
-
(2007)
J. Gastroenterol. Hepatol.
, vol.22
, Issue.1
-
-
Singh, R.1
Czaja, M.J.2
-
58
-
-
0038580372
-
Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling
-
Czaja MJ, Liu H, Wang Y. Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling. Hepatology. 2003; 37: 1405-13.
-
(2003)
Hepatology.
, vol.37
, pp. 1405-1413
-
-
Czaja, M.J.1
Liu, H.2
Wang, Y.3
-
59
-
-
33645771481
-
Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases
-
Conde de la Rosa L, Schoemaker MH, Vrenken TE et al. Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. J. Hepatol. 2006; 44: 918-29.
-
(2006)
J. Hepatol.
, vol.44
, pp. 918-929
-
-
Conde de la Rosa, L.1
Schoemaker, M.H.2
Vrenken, T.E.3
-
60
-
-
0030963238
-
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species
-
Nieminen AL, Byrne AM, Herman B, Lemasters JJ. Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. Am. J. Physiol. 1997; 272: C1286-C1294.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Nieminen, A.L.1
Byrne, A.M.2
Herman, B.3
Lemasters, J.J.4
-
61
-
-
65349122497
-
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation
-
Hong JY, Lebofsky M, Farhood A, Jaeschke H. Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2009; 296: G572-G581.
-
(2009)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.296
-
-
Hong, J.Y.1
Lebofsky, M.2
Farhood, A.3
Jaeschke, H.4
-
62
-
-
0023501875
-
Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vivo
-
Smith CV. Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vivo. Mol. Pharmacol. 1987; 32: 417-22.
-
(1987)
Mol. Pharmacol.
, vol.32
, pp. 417-422
-
-
Smith, C.V.1
-
63
-
-
0035140552
-
Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?
-
Gujral JS, Bucci TJ, Farhood A, Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology. 2001; 33: 397-405.
-
(2001)
Hepatology.
, vol.33
, pp. 397-405
-
-
Gujral, J.S.1
Bucci, T.J.2
Farhood, A.3
Jaeschke, H.4
-
64
-
-
4644238904
-
Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation
-
Gujral JS, Liu J, Farhood A, Jaeschke H. Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation. Hepatology. 2004; 40: 998-1007.
-
(2004)
Hepatology.
, vol.40
, pp. 998-1007
-
-
Gujral, J.S.1
Liu, J.2
Farhood, A.3
Jaeschke, H.4
-
65
-
-
0030021473
-
Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis
-
Aguilar HI, Botla R, Arora AS, Bronk SF, Gores GJ. Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis. Gastroenterology. 1996; 110: 558-66.
-
(1996)
Gastroenterology.
, vol.110
, pp. 558-566
-
-
Aguilar, H.I.1
Botla, R.2
Arora, A.S.3
Bronk, S.F.4
Gores, G.J.5
-
66
-
-
56149121299
-
Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury
-
Uchiyama A, Kim JS, Kon K et al. Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology. 2008; 48: 1644-54.
-
(2008)
Hepatology.
, vol.48
, pp. 1644-1654
-
-
Uchiyama, A.1
Kim, J.S.2
Kon, K.3
-
67
-
-
0030863299
-
Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide
-
Ollinger K, Roberg K. Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide. J. Biol. Chem. 1997; 272: 23707-11.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23707-23711
-
-
Ollinger, K.1
Roberg, K.2
-
68
-
-
0025881223
-
Effects of hypochlorous acid and chloramines on vascular resistance, cell integrity, and biliary glutathione disulfide in the perfused rat liver: modulation by glutathione
-
Bilzer M, Lauterburg BH. Effects of hypochlorous acid and chloramines on vascular resistance, cell integrity, and biliary glutathione disulfide in the perfused rat liver: modulation by glutathione. J. Hepatol. 1991; 13: 84-9.
-
(1991)
J. Hepatol.
, vol.13
, pp. 84-89
-
-
Bilzer, M.1
Lauterburg, B.H.2
-
70
-
-
0346874206
-
Sub-lethal oxidative stress triggers the protective effects of ischemic preconditioning in the mouse liver
-
Rüdiger HA, Graf R, Clavien PA. Sub-lethal oxidative stress triggers the protective effects of ischemic preconditioning in the mouse liver. J. Hepatol. 2003; 39: 972-7.
-
(2003)
J. Hepatol.
, vol.39
, pp. 972-977
-
-
Rüdiger, H.A.1
Graf, R.2
Clavien, P.A.3
-
71
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007; 47: 89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
73
-
-
33745522546
-
Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity
-
Cover C, Liu J, Farhood A et al. Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity. Toxicol. Appl. Pharmacol. 2006; 216: 98-107.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.216
, pp. 98-107
-
-
Cover, C.1
Liu, J.2
Farhood, A.3
-
74
-
-
57149108312
-
Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury
-
Holt MP, Cheng L, Ju C. Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury. J. Leukoc. Biol. 2008; 84: 1410-21.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 1410-1421
-
-
Holt, M.P.1
Cheng, L.2
Ju, C.3
-
75
-
-
62749148283
-
Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium
-
Smedsrød B, Le Couteur D, Ikejima K et al. Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium. Liver Int. 2009; 29: 490-501.
-
(2009)
Liver Int.
, vol.29
, pp. 490-501
-
-
Smedsrød, B.1
Le Couteur, D.2
Ikejima, K.3
-
76
-
-
1242336977
-
Dual role of tumor necrosis factor-alpha in hepatic ischemia-reperfusion injury: studies in tumor necrosis factor-alpha gene knockout mice
-
Teoh N, Field J, Sutton J, Farrell G. Dual role of tumor necrosis factor-alpha in hepatic ischemia-reperfusion injury: studies in tumor necrosis factor-alpha gene knockout mice. Hepatology. 2004; 39: 412-21.
-
(2004)
Hepatology.
, vol.39
, pp. 412-421
-
-
Teoh, N.1
Field, J.2
Sutton, J.3
Farrell, G.4
-
77
-
-
68849091034
-
A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice
-
He S, Atkinson C, Qiao F, Cianflone K, Chen X, Tomlinson S. A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. J. Clin. Invest. 2009; 119: 2304-16.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2304-2316
-
-
He, S.1
Atkinson, C.2
Qiao, F.3
Cianflone, K.4
Chen, X.5
Tomlinson, S.6
|