Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness

American Journal of Pathology

Volumn 184, Issue 5, 2014, Pages 1489-1502

  Aschner, Yael ^a,b   Khalifah, Anthony P ^a,b   Briones, Natalie ^a   Yamashita, Cory ^a,d   Dolgonos, Lior ^a,b   Young, Scott K ^a   Campbell, Megan N ^a   Riches, David W H ^a   Redente, Elizabeth F ^a   Janssen, William J ^a,b   Henson, Peter M ^a,b,c   Sap, Jan ^e   Vacaresse, Nathalie ^f   Kapus, Andras ^g,h   McCulloch, Christopher A G ^f   Zemans, Rachel L ^a,b   Downey, Gregory P ^a,b,c  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e Université Sorbonne Paris Cité   (France)

^f UNIVERSITY OF TORONTO   (Canada)

^g ST MICHAEL'S HOSPITAL   (Canada)

^h UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; COLLAGEN TYPE 1A; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE ALPHA; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CYTOKINE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW CELL; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; EMBRYO; GENE DELETION; GENE EXPRESSION; INFLAMMATION; LUNG ALVEOLUS CELL; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG PARENCHYMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WILD TYPE; 3T3 CELL LINE; ADENOVIRIDAE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; COMPLICATION; DEFICIENCY; FIBROBLAST; GENETIC TRANSCRIPTION; LUNG; METABOLISM; PATHOLOGY; PNEUMONIA; PULMONARY FIBROSIS; REPORTER GENE;

ADENOVIRIDAE; ANIMALS; BLEOMYCIN; CYTOKINES; FIBROBLASTS; GENE DELETION; GENES, REPORTER; LUNG; MICE; MICE, INBRED C57BL; NIH 3T3 CELLS; PNEUMONIA; PULMONARY FIBROSIS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 4; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899570578     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.01.016     Document Type: Article

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