Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury

American Journal of Respiratory and Critical Care Medicine

Volumn 184, Issue 5, 2011, Pages 547-560

  Janssen, William J ^a   Barthel, Lea ^a   Muldrow, Alaina ^a   Oberley Deegan, Rebecca E ^a   Kearns, Mark T ^b   Jakubzick, Claudia ^a   Henson, Peter M ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Inflammation; Monocyte

Indexed keywords

CASPASE 8; CHIMERIC ANTIBODY; FAS ANTIBODY; FAS ANTIGEN;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CELL FATE; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INFLAMMATION; INFLUENZA VIRUS A; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL;

ACUTE LUNG INJURY; ANIMALS; ANTIGENS, CD95; APOPTOSIS; BRONCHOALVEOLAR LAVAGE FLUID; CASPASE 8; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL;

EID: 80052472550     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201011-1891OC     Document Type: Article

References (63)

1. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149:818-824. (Pubitemid 24082248)
2. Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-1693. (Pubitemid 41464707)
3. Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, Connors AF Jr, Hite RD, Harabin AL. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006;354:2564-2575. (Pubitemid 43882352)
4. Desai SR, Wells AU, Rubens MB, Evans TW, Hansell DM. Acute respiratory distress syndrome: CT abnormalities at long-term followup. Radiology 1999;210:29-35. (Pubitemid 29004279)
5. Herridge MS, Cheung AM, Tansey CM,Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, et al. Oneyear outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003;348:683-693. (Pubitemid 36237037)
6. Orme J Jr, Romney JS, Hopkins RO, Pope D, Chan KJ, Thomsen G, Crapo RO, Weaver LK. Pulmonary function and health-related quality of life in survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 2003;167:690-694. (Pubitemid 36801743)
7. Matute-Bello G, Liles WC, Radella F II, Steinberg KP, Ruzinski JT, Jonas M, Chi EY, Hudson LD, Martin TR. Neutrophil apoptosis in the acute respiratory distress syndrome. Am J Respir Crit Care Med 1997;156:1969-1977. (Pubitemid 28011809)
8. Rosseau S, Hammerl P, Maus U, Walmrath HD, Schutte H, Grimminger F, Seeger W, Lohmeyer J. Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 2000;279:L25-L35. (Pubitemid 30619520)
9. Gallin JI, Snyderman R. Inflammation: basic principles and clinical correlates. Philadelphia: Lippincott Williams & Wilkins; 1999.
10. Kumar V, Abbas AK, Fausto N, Robbins SL, Cotran RS. Robbins and Cotran pathologic basis of disease. Philadelphia: Elsevier Saunders; 2005.
11. Duffield JS, Forbes SJ, Constandinou CM, Clay S, Partolina M, Vuthoori S, Wu S, Lang R, Iredale JP. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 2005;115:56-65. (Pubitemid 40385505)
12. Thepen T, van Vuuren AJ, Kiekens RC, Damen CA, Vooijs WC, van De Winkel JG. Resolution of cutaneous inflammation after local elimination of macrophages. Nat Biotechnol 2000;18:48-51. (Pubitemid 30041171)
13. Bellingan GJ, Caldwell H, Howie SE, Dransfield I, Haslett C. In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes. J Immunol 1996;157:2577-2585. (Pubitemid 126450472)
14. Cao C, Lawrence DA, Strickland DK, Zhang L. A specific role of integrin MAC-1 in accelerated macrophage efflux to the lymphatics. Blood 2005;106:3234-3241. (Pubitemid 41565924)
15. Lan HY, Nikolic-Paterson DJ, Atkins RC. Trafficking of inflammatory macrophages from the kidney to draining lymph nodes during experimental glomerulonephritis. Clin Exp Immunol 1993;92:336-341. (Pubitemid 23151047)
16. Llodra J, Angeli V, Liu J, Trogan E, Fisher EA, Randolph GJ. Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques. Proc Natl Acad Sci USA 2004;101:11779-11784. (Pubitemid 39095371)
17. Kuhlmann T, Bitsch A, Stadelmann C, Siebert H, Bruck W. Macrophages are eliminated from the injured peripheral nerve via local apoptosis and circulation to regional lymph nodes and the spleen. J Neurosci 2001;21:3401-3408. (Pubitemid 32422805)
18. Tidball JG, St Pierre BA. Apoptosis of macrophages during the resolution of muscle inflammation. J Leukoc Biol 1996;59:380-388. (Pubitemid 26135558)
19. Janssen WJ, Muldrow A, Kearns MT, Barthel L, Henson PM. Development and characterization of a lung-protective method of bone marrow transplantation in the mouse. J Immunol Methods 2010;357:1-9.
20. Hoffmann E, Krauss S, Perez D, Webby R, Webster RG. Eight-plasmid system for rapid generation of influenza virus vaccines. Vaccine 2002; 20:3165-3170.
21. Matute-Bello G, Lee JS, Frevert CW, Liles WC, Sutlief S, Ballman K, Wong V, Selk A, Martin TR. Optimal timing to repopulation of resident alveolar macrophages with donor cells following total body irradiation and bone marrow transplantation in mice. J Immunol Methods 2004;292:25-34. (Pubitemid 39179861)
22. Vermaelen K, Pauwels R. Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights. Cytometry A 2004;61:170-177. (Pubitemid 39362291)
23. Prieto J, Eklund A, Patarroyo M. Regulated expression of integrins and other adhesion molecules during differentiation of monocytes into macrophages. Cell Immunol 1994;156:191-211. (Pubitemid 24197252)
24. Curtin JF, Cotter TG. Live and let die: regulatory mechanisms in fasmediated apoptosis. Cell Signal 2003;15:983-992. (Pubitemid 37130156)
25. Baumann WR, Jung RC, Koss M, Boylen CT, Navarro L, Sharma OP. Incidence and mortality of adult respiratory distress syndrome: a prospective analysis from a large metropolitan hospital. Crit Care Med 1986;14:1-4. (Pubitemid 16188983)
26. Maus UA, Janzen S, Wall G, Srivastava M, Blackwell TS, Christman JW, Seeger W, Welte T, Lohmeyer J. Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol 2006;35:227-235. (Pubitemid 44175323)
27. Murphy J, Summer R, Wilson AA, Kotton DN, Fine A. The prolonged life-span of alveolar macrophages. Am J Respir Cell Mol Biol 2008;38: 380-385. (Pubitemid 351758683)
28. Tarling JD, Lin HS, Hsu S. Self-renewal of pulmonary alveolar macrophages: evidence from radiation chimera studies. J Leukoc Biol 1987;42:443-446.
29. Landsman L, Jung S. Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J Immunol 2007;179:3488-3494.
30. Bitterman PB, Saltzman LE, Adelberg S, Ferrans VJ, Crystal RG. Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung. J Clin Invest 1984;74:460-469. (Pubitemid 14053994)
31. Ghosh SN, Wu Q, Mader M, Fish BL, Moulder JE, Jacobs ER, Medhora M, Molthen RC. Vascular injury after whole thoracic x-ray irradiation in the rat. Int J Radiat Oncol Biol Phys 2009;74:192-199.
32. Zhang R, Ghosh SN, Zhu D, North PE, Fish BL, Morrow NV, Lowry T, Nanchal R, Jacobs ER, Moulder JE, et al. Structural and functional alterations in the rat lung following whole thoracic irradiation with moderate doses: injury and recovery. Int J Radiat Biol 2008;84:487-497. (Pubitemid 351878832)
33. Colson YL, Li H, Boggs SS, Patrene KD, Johnson PC, Ildstad ST. Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach. J Immunol 1996;157:2820-2829. (Pubitemid 126450035)
34. Johnston CJ, Williams JP, Okunieff P, Finkelstein JN. Radiationinduced pulmonary fibrosis: examination of chemokine and chemokine receptor families. Radiat Res 2002;157:256-265. (Pubitemid 34263838)
35. Soderling CC, Song CW, Blazar BR, Vallera DA. A correlation between conditioning and engraftment in recipients of MHC-mismatched T cell-depleted murine bone marrow transplants. J Immunol 1985;135: 941-946. (Pubitemid 16242780)
36. Baskiewicz-Masiuk M, Grymula K, Halasa M, Pius E, Boehlke M, Machalinski B. Induction of mixed chimerism in mice by employing different conditioning protocols and bone marrow cell transplantation. Transplant Proc 2009;41:1894-1899.
37. Kezic J, McMenamin PG. Differential turnover rates of monocytederived cells in varied ocular tissue microenvironments. J Leukoc Biol 2008;84:721-729.
38. Wacker HH, Radzun HJ, Parwaresch MR. Kinetics of Kupffer cells as shown by parabiosis and combined autoradiographic/immunohistochemical analysis. Virchows Arch B Cell Pathol Incl Mol Pathol 1986; 51:71-78. (Pubitemid 16082880)
39. Gardai SJ, Xiao YQ, Dickinson M, Nick JA, Voelker DR, Greene KE, Henson PM. By binding sirpalpha or calreticulin/cd91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell 2003;115:13-23. (Pubitemid 37255314)
40. Neznanov N, Neznanova L, Kondratov RV, Burdelya L, Kandel ES, O'Rourke DM, Ullrich A, Gudkov AV. Dominant negative form of signal-regulatory protein-alpha (sirpalpha/SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-kappa B. J Biol Chem 2003;278:3809-3815. (Pubitemid 36801108)
41. White MK, Baireddy V, Strayer DS. Natural protection from apoptosis by surfactant protein A in type II pneumocytes. Exp Cell Res 2001; 263:183-192. (Pubitemid 32989092)
42. Monick MM, Mallampalli RK, Bradford M, McCoy D, Gross TJ, Flaherty DM, Powers LS, Cameron K, Kelly S, Merrill AH Jr, et al. Cooperative prosurvival activity by erk and akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. J Immunol 2004;173:123-135. (Pubitemid 38797333)
43. Taut K, Winter C, Briles DE, Paton JC, Christman JW, Maus R, Baumann R, Welte T, Maus UA. Macrophage turnover kinetics in the lungs of mice infected with Streptococcus pneumoniae. Am J Respir Cell Mol Biol 2008;38:105-113.
44. Gross NJ. Alveolar macrophage number: an index of the effect of radiation on the lungs. Radiat Res 1977;72:325-332. (Pubitemid 8220386)
45. Peel DM, Coggle JE. The effect of x irradiation on alveolar macrophages in mice. Radiat Res 1980;81:10-19. (Pubitemid 10180199)
46. Marguet D, Luciani MF, Moynault A, Williamson P, Chimini G. Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyte and prey. Nat Cell Biol 1999; 1:454-456. (Pubitemid 129502814)
47. Dockrell DH, Marriott HM, Prince LR, Ridger VC, Ince PG, Hellewell PG, Whyte MK. Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection. J Immunol 2003;171:5380-5388. (Pubitemid 37432824)
48. Kirby AC, Coles MC, Kaye PM. Alveolar macrophages transport pathogens to lung draining lymph nodes. J Immunol 2009;183:1983-1989.
49. Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol 2002; 161:1783-1796. (Pubitemid 35265536)
50. Matute-Bello G, Liles WC, Steinberg KP, Kiener PA, Mongovin S, Chi EY, Jonas M, Martin TR. Soluble fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol 1999; 163:2217-2225. (Pubitemid 29382230)
51. Kitamura Y, Hashimoto S, Mizuta N, Kobayashi A, Kooguchi K, Fujiwara I, Nakajima H. Fas/fasl-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice. Am J Respir Crit Care Med 2001;163:762-769. (Pubitemid 32230841)
52. Wajant H. The fas signaling pathway: More than a paradigm. Science 2002;296:1635-1636. (Pubitemid 34579146)
53. Dalton JE, Howell G, Pearson J, Scott P, Carding SR. Fas-fas ligand interactions are essential for the binding to and killing of activated macrophages by gamma delta T cells. J Immunol 2004;173:3660-3667. (Pubitemid 39280726)
54. Kirby AC, Newton DJ, Carding SR, Kaye PM. Pulmonary dendritic cells and alveolar macrophages are regulated by gammadelta T cells during the resolution of S. pneumoniae-induced inflammation. J Pathol 2007; 212:29-37. (Pubitemid 46746287)
55. Brown SB, Savill J. Phagocytosis triggers macrophage release of fas ligand and induces apoptosis of bystander leukocytes. J Immunol 1999;162:480-485. (Pubitemid 29018957)
56. Matute-Bello G, Liles WC, Frevert CW, Nakamura M, Ballman K, Vathanaprida C, Kiener PA, Martin TR. Recombinant human fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits. Am J Physiol Lung Cell Mol Physiol 2001;281:L328-L335.
57. Matute-Bello G, Winn RK, Jonas M, Chi EY, Martin TR, Liles WC. Fas (cd95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation. Am J Pathol 2001;158:153-161. (Pubitemid 32096480)
58. Neff TA, Guo RF, Neff SB, Sarma JV, Speyer CL, Gao H, Bernacki KD, Huber-Lang M, McGuire S, Hoesel LM, et al. Relationship of acute lung inflammatory injury to fas/fasl system. Am J Pathol 2005; 166:685-694. (Pubitemid 40315626)
59. Perl M, Chung CS, Perl U, Lomas-Neira J, de PaepeM, Cioffi WG, Ayala A. Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury. Am J Respir Crit Care Med 2007;176:591-601. (Pubitemid 47403277)
60. Matute-Bello G, Lee JS, Liles WC, Frevert CW, Mongovin S, Wong V, Ballman K, Sutlief S, Martin TR. Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol 2005;175:4069-4075. (Pubitemid 41292070)
61. Janssen WJ, McPhillips KA, Dickinson MG, Linderman DJ, Morimoto K, Xiao YQ, Oldham KM, Vandivier RW, Henson PM, Gardai SJ. Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha. Am J Respir Crit Care Med 2008;178:158-167. (Pubitemid 351957774)
62. Wiezorek J, Holland P, Graves J. Death receptor agonists as a targeted therapy for cancer. Clin Cancer Res 2010;16:1701-1708.
63. Micheau O. Cellular flice-inhibitory protein: An attractive therapeutic target? Expert Opin Ther Targets 2003;7:559-573. (Pubitemid 37063342)