Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts

Current Biology

Volumn 9, Issue 10, 1999, Pages 505-511

  Su, Jing ^a,b   Muranjan, Madhavi ^a   Sap, Jan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SIBS Novo Nordisk Translational Research Centre for PreDiabetes   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; GALLUS GALLUS;

EID: 0033587069     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80234-6     Document Type: Article

References (39)

1. Thomas SM, Soriano P, Imamoto A: Specific and redundant roles of src and fyn in organizing the cytoskeleton. Nature 1995, 376:267-271.
2. Guan JL, Shalloway D: Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation. Nature 1992, 358:390-392.
3. Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT: P130cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J Biol Chem 1996, 271:13649-13655.
4. Vuori K, Hirai H, Aizawa S, Ruoslahti E: Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: A role for src family kinases. Mol Cell Biol 1996, 16:2606-2613.
5. Schwartz MA, Schaller MD, Ginsberg MH: Integrins: Emerging paradigms of signal transduction. Annu Rev Cell Dev Biol 1995, 11:549-599.
6. Thomas SM, Brugge JS: Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 1997, 13:513-609.
7. Parsons JT, Parsons SJ: Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways. Curr Opin Cell Biol 1997, 9:187-192.
8. Schlaepfer DD, Broome MA, Hunter T: Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: Involvement of the grb2, p130cas, and nck adaptor proteins. Mol Cell Biol 1997, 17:1702-1713.
9. Kaplan KB, Swedlow JR, Morgan DO, Varmus HE: c-Src enhances the spreading of src-/- Fibroblasts on fibronectin by a kinase-independent mechanism. Genes Dev 1995, 9:1505-1517.
10. Wary KK, Mariotti A, Zurzolo C, Giancotti FG: A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 1998, 94:625-634.
11. Nada S, Okada M, Macauley A, Cooper J, Nakagawa H: Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature 1991, 351:69-72.
12. Davidson D, Chow LM, Veillette A: Chk, a Csk family tyrosine protein kinase, exhibits Csk-like activity in fibroblasts, but not in an antigen-specific T-cell line. J Biol Chem 1997, 272:1355-1362.
13. Schwartzberg PL: The many faces of Src: Multiple functions of a prototypical tyrosine kinase. Oncogens 1998, 17:1463-1468.
14. Trowbridge IS, Thomas ML: CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu Rev Immunol 1994, 12:85-116.
15. Neel BG, Tonks NK: Protein tyrosine phosphatases in signal transduction. Curr Opin Cell Biol 1997, 9:193-204.
16. Roach T, Slater S, Koval M, White L, McFarland EC, Okumura M, et al.: CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr Biol 1997, 7:408-417.
17. Sap J, D'Eustacchio P, Givol D, Schlessinger J: Cloning and expression of a widely expressed receptor tyrosine phosphatase. Proc Natl Acad Sci USA 1990, 87:6112-6116.
18. Zheng XM, Wang Y, Pallen CJ: Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase. Nature 1992, 359:336-339.
19. den Hertog J, Pals Cegm, Peppelenbosch M, Tertoolen LGJ, De Laat SW, Kruijer W: Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation. EMBO J 1993, 12:3789-3798.
20. Moller NP, Moller KB, Lammers R, Kharitonenkov A, Hoppe E, Wiberg FC, et al.: Selective down-regulation of the insulin receptor signal by protein-tyrosine phosphatases alpha and epsilon. J Biol Chem 1995 270:23126-23131.
21. Harder KW, Moller NPH, Peacock JW, Jirik FR: Protein-tyrosine phosphatase alpha regulates src family kinases and alters cell-substratum adhesion. J Biol Chem 1998, 273:31890-31900.
22. Kawakatsu H, Sakai T, Takagaki Y, Shinoda Y, Saito M, Owada MK, et al.: A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase. J Biol Chem 1996, 271:5680-5685.
23. Schlaepfer DD, Hanks SK, Hunter T, Van der Geer P: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994, 372:786-791.
24. Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG: The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 1996, 87:733-743.
25. Somani AK, Bignon JS, Mills GB, Siminovitch KA, Branch DR: Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase. J Biol Chem 1997, 272:21113-21119.
26. Lorenz U, Ravichandran KS, Burakoff SJ, Neel BG: Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness. Proc Natl Acad Sci USA 1996, 93:9624-9629.
27. Peng Z-Y, Cartwright CA: Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. Oncogene 1995, 11:1955-1962.
28. Oh E-S, Gu H, Saxton TM, Timms JF, Hausdorff S, Frevert EU, et al.: Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2. Mol Cell Biol 1999, 19:3205-3215.
29. Bhandari V, Lim KL, Pallen CJ: Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn. J Biol Chem 1998, 273:8691-8698.
30. Neel BG: Role of phosphatases in lymphocyte activation. Curr Opin Immunol 1997, 9:405-420.
31. Yu D-H, Qu C-K, Henegariu O, Lu X, Feng G-S: Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J Biol Chem 1998, 273:21125-21131.
32. Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM: Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998, 280:1614-1617.
33. Gu J, Tamura M, Yamada KM: Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 1998, 143:1375-1383.
34. Angers-Loustau A, Cote J-F, Charest A, Dowbenko D, Spencer S, Lasky LA, et al.: Protein tyrosine phosphatase-Pest regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol 1999, 144:1019-1031.
35. Soriano P, Montgomery C, Geske R, Bradley A: Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 1991, 64:693-702.
36. Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, et al.: Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- Mutant mice. Genes Dev 1997, 11:2835-2844.
37. Schmidt A, Rutledge SJ, Endo N, Opas EE, Tanaka H, Wesolowski G, et al.: Protein-tyrosine phosphatase activity regulates osteoclast formation and function: Inhibition by alendronate. Proc Natl Acad Sci USA 1996, 93:3068-3073.
38. Mountford P, Zevnik B, Duwel A, Nichols J, Li M, Dani C, et al.: Dicistronic targeting constructs: Reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci USA 1994, 91:4303-4307.
39. Wong EC, Mullersman JE, Thomas ML: Leukocyte common antigen-related phosphatase (LRP) gene structure: Conservation of the genomic organization of transmembrane protein tyrosine phosphatases. Genomics 1993, 17:33-38.