-
2
-
-
0000683245
-
Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins
-
Scriver CR, Sly WS, Childs B, et al, editors 8th edition. New York: McGraw-Hill Professional
-
Kane JP. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In: Scriver CR, Sly WS, Childs B, et al, editors. The metabolic and molecular bases of inherited disease, 8th edition. New York: McGraw-Hill Professional, 2001.
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
-
-
Kane, J.P.1
-
3
-
-
0026470990
-
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
-
1439810
-
Wetterau JR, Aggerbeck LP, Bouma ME, Eisenberg C, Munck A, Hermier M, Schmitz J, Gay G, Rader DJ, Gregg RE. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science. 1992;258:999-1001.
-
(1992)
Science
, vol.258
, pp. 999-1001
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Bouma, M.E.3
Eisenberg, C.4
Munck, A.5
Hermier, M.6
Schmitz, J.7
Gay, G.8
Rader, D.J.9
Gregg, R.E.10
-
4
-
-
33846151732
-
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
-
17215532
-
Cuchel M, Bloedon LT, Szapary PO, Kolansky DM, Wolfe ML, Sarkis A, Millar JS, Ikewaki K, Siegelman ES, Gregg RE, Rader DJ. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N Engl J Med. 2007;356:148-56.
-
(2007)
N Engl J Med
, vol.356
, pp. 148-156
-
-
Cuchel, M.1
Bloedon, L.T.2
Szapary, P.O.3
Kolansky, D.M.4
Wolfe, M.L.5
Sarkis, A.6
Millar, J.S.7
Ikewaki, K.8
Siegelman, E.S.9
Gregg, R.E.10
Rader, D.J.11
-
5
-
-
84871945617
-
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: A single-arm, open-label, phase 3 study
-
23122768
-
Cuchel M, Meagher EA, du Toit TH, Blom DJ, Marais AD, Hegele RA, Averna MR, Sirtori CR, Shah PK, Gaudet D, Stefanutti C, Vigna GB, Du Plessis AM, Propert KJ, Sasiela WJ, Bloedon LT, Rader DJ. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. Lancet. 2013;381:40-6.
-
(2013)
Lancet
, vol.381
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
Du Toit, T.H.3
Blom, D.J.4
Marais, A.D.5
Hegele, R.A.6
Averna, M.R.7
Sirtori, C.R.8
Shah, P.K.9
Gaudet, D.10
Stefanutti, C.11
Vigna, G.B.12
Du Plessis, A.M.13
Propert, K.J.14
Sasiela, W.J.15
Bloedon, L.T.16
Rader, D.J.17
-
7
-
-
48349088178
-
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
-
18506154
-
Samaha FF, McKenney J, Bloedon LT, Sasiela WJ, Rader DJ. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat Clin Pract Cardiovasc Med. 2008;5:497-505.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, pp. 497-505
-
-
Samaha, F.F.1
McKenney, J.2
Bloedon, L.T.3
Sasiela, W.J.4
Rader, D.J.5
-
9
-
-
84857133310
-
Multiple functions of microsomal triglyceride transfer protein
-
Hussain MM, Rava P, Walsh M, Rana M, Iqbal J. Multiple functions of microsomal triglyceride transfer protein. Nutr Metab (Lond). 2012;9:14.
-
(2012)
Nutr Metab (Lond)
, vol.9
, pp. 14
-
-
Hussain, M.M.1
Rava, P.2
Walsh, M.3
Rana, M.4
Iqbal, J.5
-
10
-
-
50649121449
-
Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition
-
18502767
-
Iqbal J, Rudeland LL, Hussain MM. Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition. J Biol Chem. 2008;283:19967-80.
-
(2008)
J Biol Chem
, vol.283
, pp. 19967-19980
-
-
Iqbal, J.1
Rudeland, L.L.2
Hussain, M.M.3
-
11
-
-
0035081589
-
Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: Structure and function in atherosclerosis
-
11264983
-
Rudel LL, Leeand RG, Cockman TL. Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol. 2001;12:121-7.
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 121-127
-
-
Rudel, L.L.1
Leeand, R.G.2
Cockman, T.L.3
-
13
-
-
0034987223
-
Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2
-
11353332
-
Chang TY, Chang CC, Lin S, Yu C, Li BL, Miyazaki A. Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2. Curr Opin Lipidol. 2001;12:289-96.
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 289-296
-
-
Chang, T.Y.1
Chang, C.C.2
Lin, S.3
Yu, C.4
Li, B.L.5
Miyazaki, A.6
-
14
-
-
0036169936
-
Decreased microsomal triglyceride transfer protein activity contributes to initiation of alcoholic liver steatosis in rats
-
11830326
-
Sugimoto T, Yamashita S, Ishigami M, Sakai N, Hirano K, Tahara M, Matsumoto K, Nakamura T, Matsuzawa Y. Decreased microsomal triglyceride transfer protein activity contributes to initiation of alcoholic liver steatosis in rats. J Hepatol. 2002;36:157-62.
-
(2002)
J Hepatol
, vol.36
, pp. 157-162
-
-
Sugimoto, T.1
Yamashita, S.2
Ishigami, M.3
Sakai, N.4
Hirano, K.5
Tahara, M.6
Matsumoto, K.7
Nakamura, T.8
Matsuzawa, Y.9
-
15
-
-
18244365866
-
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
-
11818366
-
Perlemuter G, Sabile A, Letteron P, Vona G, Topilco A, Chretien Y, Koike K, Pessayre D, Chapman J, Barba G, Brechot C. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. Faseb J. 2002;16:185-94.
-
(2002)
Faseb J
, vol.16
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
Vona, G.4
Topilco, A.5
Chretien, Y.6
Koike, K.7
Pessayre, D.8
Chapman, J.9
Barba, G.10
Brechot, C.11
-
16
-
-
77649312075
-
Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP)
-
Mirandola S, Bowman D, Hussain MM, Alberti A. Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP). Nutr Metab (Lond). 2010;7:13.
-
(2010)
Nutr Metab (Lond)
, vol.7
, pp. 13
-
-
Mirandola, S.1
Bowman, D.2
Hussain, M.M.3
Alberti, A.4
-
17
-
-
34447136796
-
Inhibiting proteasomal degradation of microsomal triglyceride transfer protein prevents CCl4-induced steatosis
-
17405876
-
Pan X, Hussain FN, Iqbal J, Feuerman MH, Hussain MM. Inhibiting proteasomal degradation of microsomal triglyceride transfer protein prevents CCl4-induced steatosis. J Biol Chem. 2007;282:17078-89.
-
(2007)
J Biol Chem
, vol.282
, pp. 17078-17089
-
-
Pan, X.1
Hussain, F.N.2
Iqbal, J.3
Feuerman, M.H.4
Hussain, M.M.5
-
18
-
-
84877914445
-
Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1alpha/cJun to enhance plasma ALT/AST
-
23532846
-
Josekutty J, Iqbal J, Iwawaki T, Kohno K, Hussain MM. Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1alpha/cJun to enhance plasma ALT/AST. J Biol Chem. 2013;288:14372-83.
-
(2013)
J Biol Chem
, vol.288
, pp. 14372-14383
-
-
Josekutty, J.1
Iqbal, J.2
Iwawaki, T.3
Kohno, K.4
Hussain, M.M.5
-
19
-
-
54049150442
-
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
-
Andersonand N, Borlak J. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol Rev. 2008;60:311-57.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 311-357
-
-
Andersonand, N.1
Borlak, J.2
-
20
-
-
84888027087
-
Review of treatment options for nonalcoholic fatty liver disease
-
24266914
-
Corrado RL, Torresand DM, Harrison SA. Review of treatment options for nonalcoholic fatty liver disease. Med Clin N Am. 2014;98:55-72.
-
(2014)
Med Clin N Am
, vol.98
, pp. 55-72
-
-
Corrado, R.L.1
Torresand, D.M.2
Harrison, S.A.3
-
21
-
-
84861543083
-
The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
-
22488764
-
Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M, Sanyal AJ. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology. 2012;55:2005-23.
-
(2012)
Hepatology
, vol.55
, pp. 2005-2023
-
-
Chalasani, N.1
Younossi, Z.2
Lavine, J.E.3
Diehl, A.M.4
Brunt, E.M.5
Cusi, K.6
Charlton, M.7
Sanyal, A.J.8
-
22
-
-
77952529040
-
A position statement on NAFLD/NASH based on the EASL 2009 special conference
-
20494470
-
Ratziu V, Bellentani S, Cortez-Pinto H, Day C, Marchesini G. A position statement on NAFLD/NASH based on the EASL 2009 special conference. J Hepatol. 2010;53:372-84.
-
(2010)
J Hepatol
, vol.53
, pp. 372-384
-
-
Ratziu, V.1
Bellentani, S.2
Cortez-Pinto, H.3
Day, C.4
Marchesini, G.5
-
23
-
-
80052102126
-
Weight reduction for non-alcoholic fatty liver disease
-
Peng L, Wang J, Li F. Weight reduction for non-alcoholic fatty liver disease. Cochrane Database Syst Rev. 2011;(6):CD003619
-
(2011)
Cochrane Database Syst Rev.
, Issue.6
-
-
Peng, L.1
Wang, J.2
Li, F.3
-
24
-
-
83555176039
-
Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review
-
21723839
-
Thoma C, Dayand CP, Trenell MI. Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review. J Hepatol. 2012;56:255-66.
-
(2012)
J Hepatol
, vol.56
, pp. 255-266
-
-
Thoma, C.1
Dayand, C.P.2
Trenell, M.I.3
-
25
-
-
36849090857
-
Review article: Non-alcoholic fatty liver disease in morbidly obese patients and the effect of bariatric surgery
-
18081662
-
De Ridder RJ, Schoon EJ, Smulders JF, van Hout GC, Stockbrugger RW, Koek GH. Review article: non-alcoholic fatty liver disease in morbidly obese patients and the effect of bariatric surgery. Aliment Pharmacol Ther. 2007;26(suppl 2):195-201.
-
(2007)
Aliment Pharmacol Ther
, vol.26
, Issue.SUPPL. 2
, pp. 195-201
-
-
De Ridder, R.J.1
Schoon, E.J.2
Smulders, J.F.3
Van Hout, G.C.4
Stockbrugger, R.W.5
Koek, G.H.6
-
26
-
-
78149283488
-
Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes
-
20664019
-
Lazo M, Solga SF, Horska A, Bonekamp S, Diehl AM, Brancati FL, Wagenknecht LE, Pi-Sunyer FX, Kahn SE, Clark JM. Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes. Diabetes Care. 2010;33:2156-63.
-
(2010)
Diabetes Care
, vol.33
, pp. 2156-2163
-
-
Lazo, M.1
Solga, S.F.2
Horska, A.3
Bonekamp, S.4
Diehl, A.M.5
Brancati, F.L.6
Wagenknecht, L.E.7
Pi-Sunyer, F.X.8
Kahn, S.E.9
Clark, J.M.10
-
27
-
-
66749184903
-
Lifestyle intervention in obese children with non-alcoholic fatty liver disease: 2-year follow-up study
-
19224892
-
Reinehr T, Schmidt C, Toschke AM, Andler W. Lifestyle intervention in obese children with non-alcoholic fatty liver disease: 2-year follow-up study. Arch Dis Child. 2009;94:437-42.
-
(2009)
Arch Dis Child
, vol.94
, pp. 437-442
-
-
Reinehr, T.1
Schmidt, C.2
Toschke, A.M.3
Andler, W.4
-
28
-
-
73449116035
-
Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis
-
19827166
-
Promrat K, Kleiner DE, Niemeier HM, Jackvony E, Kearns M, Wands JR, Fava JL, Wing RR. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis. Hepatology. 2010;51:121-9.
-
(2010)
Hepatology
, vol.51
, pp. 121-129
-
-
Promrat, K.1
Kleiner, D.E.2
Niemeier, H.M.3
Jackvony, E.4
Kearns, M.5
Wands, J.R.6
Fava, J.L.7
Wing, R.R.8
-
29
-
-
58949102847
-
Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial
-
19053049
-
Harrison SA, Fecht W, Brunt EM, Neuschwander-Tetri BA. Orlistat for overweight subjects with nonalcoholic steatohepatitis: a randomized, prospective trial. Hepatology. 2009;49:80-6.
-
(2009)
Hepatology
, vol.49
, pp. 80-86
-
-
Harrison, S.A.1
Fecht, W.2
Brunt, E.M.3
Neuschwander-Tetri, B.A.4
-
30
-
-
47149086771
-
Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: A randomized, controlled trial
-
18537181
-
Nobili V, Manco M, Devito R, Di Ciommo V, Comparcola D, Sartorelli MR, Piemonte F, Marcellini M, Angulo P. Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: a randomized, controlled trial. Hepatology. 2008;48:119-28.
-
(2008)
Hepatology
, vol.48
, pp. 119-128
-
-
Nobili, V.1
Manco, M.2
Devito, R.3
Di Ciommo, V.4
Comparcola, D.5
Sartorelli, M.R.6
Piemonte, F.7
Marcellini, M.8
Angulo, P.9
-
31
-
-
80051545931
-
Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss
-
21708823
-
Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, Day CP, Trenell MI. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut. 2011;60:1278-83.
-
(2011)
Gut
, vol.60
, pp. 1278-1283
-
-
Hallsworth, K.1
Fattakhova, G.2
Hollingsworth, K.G.3
Thoma, C.4
Moore, S.5
Taylor, R.6
Day, C.P.7
Trenell, M.I.8
-
32
-
-
70350072281
-
Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss
-
19637289
-
Johnson NA, Sachinwalla T, Walton DW, Smith K, Armstrong A, Thompson MW, George J. Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology. 2009;50:1105-12.
-
(2009)
Hepatology
, vol.50
, pp. 1105-1112
-
-
Johnson, N.A.1
Sachinwalla, T.2
Walton, D.W.3
Smith, K.4
Armstrong, A.5
Thompson, M.W.6
George, J.7
-
33
-
-
33646483917
-
A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease
-
16630771
-
Zelber-Sagi S, Kessler A, Brazowsky E, Webb M, Lurie Y, Santo M, Leshno M, Blendis L, Halpern Z, Oren R. A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2006;4:639-44.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 639-644
-
-
Zelber-Sagi, S.1
Kessler, A.2
Brazowsky, E.3
Webb, M.4
Lurie, Y.5
Santo, M.6
Leshno, M.7
Blendis, L.8
Halpern, Z.9
Oren, R.10
-
34
-
-
0141515773
-
The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis
-
14502318
-
Sabuncu T, Nazligul Y, Karaoglanoglu M, Ucar E, Kilic FB. The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis. Rom J Gastroenterol. 2003;12:189-92.
-
(2003)
Rom J Gastroenterol
, vol.12
, pp. 189-192
-
-
Sabuncu, T.1
Nazligul, Y.2
Karaoglanoglu, M.3
Ucar, E.4
Kilic, F.B.5
-
35
-
-
34547423962
-
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
-
17526015
-
Gary-Bobo M, Elachouri G, Gallas JF, Janiak P, Marini P, Ravinet-Trillou C, Chabbert M, Cruccioli N, Pfersdorff C, Roque C, Arnone M, Croci T, Soubrie P, Oury-Donat F, Maffrand JP, Scatton B, Lacheretz F, Le Fur G, Herbert JM, Bensaid M. Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats. Hepatology. 2007;46:122-9.
-
(2007)
Hepatology.
, vol.46
, pp. 122-129
-
-
Gary-Bobo, M.1
Elachouri, G.2
Gallas, J.F.3
Janiak, P.4
Marini, P.5
Ravinet-Trillou, C.6
Chabbert, M.7
Cruccioli, N.8
Pfersdorff, C.9
Roque, C.10
Arnone, M.11
Croci, T.12
Soubrie, P.13
Oury-Donat, F.14
Maffrand, J.P.15
Scatton, B.16
Lacheretz, F.17
Le Fur, G.18
Herbert, J.M.19
Bensaid, M.20
more..
-
36
-
-
50249115145
-
Piperine, the potential functional food for mood and cognitive disorders
-
18639606
-
Wattanathorn J, Chonpathompikunlert P, Muchimapura S, Priprem A, Tankamnerdthai O. Piperine, the potential functional food for mood and cognitive disorders. Food Chem Toxicol. 2008;46:3106-10.
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 3106-3110
-
-
Wattanathorn, J.1
Chonpathompikunlert, P.2
Muchimapura, S.3
Priprem, A.4
Tankamnerdthai, O.5
-
37
-
-
84868461692
-
Piperine, an LXRalpha antagonist, protects against hepatic steatosis and improves insulin signaling in mice fed a high-fat diet
-
23000915
-
Jwa H, Choi Y, Park UH, Um SJ, Yoon SK, Park T. Piperine, an LXRalpha antagonist, protects against hepatic steatosis and improves insulin signaling in mice fed a high-fat diet. Biochem Pharmacol. 2012;84:1501-10.
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 1501-1510
-
-
Jwa, H.1
Choi, Y.2
Park, U.H.3
Um, S.J.4
Yoon, S.K.5
Park, T.6
-
38
-
-
84884540840
-
Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice
-
23993530
-
Choi S, Choi Y, Choi Y, Kim S, Jang J, Park T. Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice. Food Chem. 2013;141:3627-35.
-
(2013)
Food Chem
, vol.141
, pp. 3627-3635
-
-
Choi, S.1
Choi, Y.2
Choi, Y.3
Kim, S.4
Jang, J.5
Park, T.6
-
39
-
-
1642527221
-
Experimental studies of oxymatrine and its mechanisms of action in hepatitis B and C viral infections
-
Wuand XN, Wang GJ. Experimental studies of oxymatrine and its mechanisms of action in hepatitis B and C viral infections. Chin J Dig Dis. 2004;5:12-6.
-
(2004)
Chin J Dig Dis
, vol.5
, pp. 12-16
-
-
Wuand, X.N.1
Wang, G.J.2
-
40
-
-
84879829639
-
Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparalpha)
-
23791610
-
Shi LJ, Shi L, Song GY, Zhang HF, Hu ZJ, Wang C, Zhang DH. Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparalpha). Eur J Pharmacol. 2013;714:89-95.
-
(2013)
Eur J Pharmacol
, vol.714
, pp. 89-95
-
-
Shi, L.J.1
Shi, L.2
Song, G.Y.3
Zhang, H.F.4
Hu, Z.J.5
Wang, C.6
Zhang, D.H.7
-
41
-
-
84876513743
-
Hepatoprotective effects of Juglans regia extract against CCl4-induced oxidative damage in rats
-
23373712
-
Eidi A, Moghadam JZ, Mortazavi P, Rezazadeh S, Olamafar S. Hepatoprotective effects of Juglans regia extract against CCl4-induced oxidative damage in rats. Pharm Biol. 2013;51:558-65.
-
(2013)
Pharm Biol
, vol.51
, pp. 558-565
-
-
Eidi, A.1
Moghadam, J.Z.2
Mortazavi, P.3
Rezazadeh, S.4
Olamafar, S.5
-
42
-
-
84896727966
-
Dietary walnut oil modulates liver steatosis in the obese Zucker rat
-
23942585
-
Fink A, Rufer CE, Le Grandois J, Roth A, Aoude-Werner D, Marchioni E, Bub A, Barth SW. Dietary walnut oil modulates liver steatosis in the obese Zucker rat. Eur J Nutr. 2014;53:645-60.
-
(2014)
Eur J Nutr
, vol.53
, pp. 645-660
-
-
Fink, A.1
Rufer, C.E.2
Le Grandois, J.3
Roth, A.4
Aoude-Werner, D.5
Marchioni, E.6
Bub, A.7
Barth, S.W.8
-
43
-
-
80052021843
-
Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells
-
Zhang J, Grieger JA, Kris-Etherton PM, Thompson JT, Gillies PJ, Fleming JA, Vanden HJ. Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells. Nutr Metab (Lond). 2011;8:61.
-
(2011)
Nutr Metab (Lond)
, vol.8
, pp. 61
-
-
Zhang, J.1
Grieger, J.A.2
Kris-Etherton, P.M.3
Thompson, J.T.4
Gillies, P.J.5
Fleming, J.A.6
Vanden, H.J.7
-
44
-
-
84878246396
-
Acute consumption of walnuts and walnut components differentially affect postprandial lipemia, endothelial function, oxidative stress, and cholesterol efflux in humans with mild hypercholesterolemia
-
23616506
-
Berryman CE, Grieger JA, West SG, Chen CY, Blumberg JB, Rothblat GH, Sankaranarayanan S, Kris-Etherton PM. Acute consumption of walnuts and walnut components differentially affect postprandial lipemia, endothelial function, oxidative stress, and cholesterol efflux in humans with mild hypercholesterolemia. J Nutr. 2013;143:788-94.
-
(2013)
J Nutr
, vol.143
, pp. 788-794
-
-
Berryman, C.E.1
Grieger, J.A.2
West, S.G.3
Chen, C.Y.4
Blumberg, J.B.5
Rothblat, G.H.6
Sankaranarayanan, S.7
Kris-Etherton, P.M.8
-
45
-
-
67649863729
-
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: A meta-analysis and systematic review
-
Baneland DK, Hu FB. Effects of walnut consumption on blood lipids and other cardiovascular risk factors: a meta-analysis and systematic review. Am J Clin Nutr. 2009;90:56-63.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 56-63
-
-
Baneland, D.K.1
Hu, F.B.2
-
46
-
-
75149154306
-
Effects of walnut consumption on endothelial function in type 2 diabetic subjects: A randomized controlled crossover trial
-
19880586
-
Ma Y, Njike VY, Millet J, Dutta S, Doughty K, Treu JA, Katz DL. Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial. Diabetes Care. 2010;33:227-32.
-
(2010)
Diabetes Care
, vol.33
, pp. 227-232
-
-
Ma, Y.1
Njike, V.Y.2
Millet, J.3
Dutta, S.4
Doughty, K.5
Treu, J.A.6
Katz, D.L.7
-
47
-
-
84864290671
-
Lipid-lowering agents in nonalcoholic fatty liver disease and steatohepatitis: Human studies
-
22419057
-
Nseir W, Mograbiand J, Ghali M. Lipid-lowering agents in nonalcoholic fatty liver disease and steatohepatitis: human studies. Dig Dis Sci. 2012;57:1773-81.
-
(2012)
Dig Dis Sci
, vol.57
, pp. 1773-1781
-
-
Nseir, W.1
Mograbiand, J.2
Ghali, M.3
-
48
-
-
0036805674
-
Statins as anti-inflammatory agents
-
12368073
-
Weitz-Schmidt G. Statins as anti-inflammatory agents. Trends Pharmacol Sci. 2002;23:482-6.
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 482-486
-
-
Weitz-Schmidt, G.1
-
49
-
-
78349267131
-
Long-term statin therapy affects the severity of chronic gastritis
-
21073607
-
Nseir W, Khateeb J, Tatour I, Haiek S, Samara M, Assy N. Long-term statin therapy affects the severity of chronic gastritis. Helicobacter. 2010;15:510-5.
-
(2010)
Helicobacter
, vol.15
, pp. 510-515
-
-
Nseir, W.1
Khateeb, J.2
Tatour, I.3
Haiek, S.4
Samara, M.5
Assy, N.6
-
51
-
-
34249342305
-
Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: A histopathological follow-up study
-
17400325
-
Ekstedt M, Franzen LE, Mathiesen UL, Holmqvist M, Bodemar G, Kechagias S. Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: a histopathological follow-up study. J Hepatol. 2007;47:135-41.
-
(2007)
J Hepatol
, vol.47
, pp. 135-141
-
-
Ekstedt, M.1
Franzen, L.E.2
Mathiesen, U.L.3
Holmqvist, M.4
Bodemar, G.5
Kechagias, S.6
-
52
-
-
78649890465
-
Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek atorvastatin and coronary heart disease evaluation (GREACE) study: A post-hoc analysis
-
21109302
-
Athyros VG, Tziomalos K, Gossios TD, Griva T, Anagnostis P, Kargiotis K, Pagourelias ED, Theocharidou E, Karagiannis A, Mikhailidis DP. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek atorvastatin and coronary heart disease evaluation (GREACE) study: a post-hoc analysis. Lancet. 2010;376:1916-22.
-
(2010)
Lancet
, vol.376
, pp. 1916-1922
-
-
Athyros, V.G.1
Tziomalos, K.2
Gossios, T.D.3
Griva, T.4
Anagnostis, P.5
Kargiotis, K.6
Pagourelias, E.D.7
Theocharidou, E.8
Karagiannis, A.9
Mikhailidis, D.P.10
-
53
-
-
2342456307
-
Pravastatin in patients with nonalcoholic steatohepatitis: Results of a pilot study
-
15135271
-
Rallidis LS, Drakoulisand CK, Parasi AS. Pravastatin in patients with nonalcoholic steatohepatitis: results of a pilot study. Atherosclerosis. 2004;174:193-6.
-
(2004)
Atherosclerosis
, vol.174
, pp. 193-196
-
-
Rallidis, L.S.1
Drakoulisand, C.K.2
Parasi, A.S.3
-
54
-
-
84856951127
-
Efficacy of pitavastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study
-
21951922
-
Hyogo H, Ikegami T, Tokushige K, Hashimoto E, Inui K, Matsuzaki Y, Tokumo H, Hino F, Tazuma S. Efficacy of pitavastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: an open-label, pilot study. Hepatol Res. 2011;41:1057-65.
-
(2011)
Hepatol Res
, vol.41
, pp. 1057-1065
-
-
Hyogo, H.1
Ikegami, T.2
Tokushige, K.3
Hashimoto, E.4
Inui, K.5
Matsuzaki, Y.6
Tokumo, H.7
Hino, F.8
Tazuma, S.9
-
55
-
-
70350474571
-
Effects of lovastatin and pentoxyphyllin in nonalcoholic steatohepatitis
-
19760953
-
Mihaila RG, Nedelcu L, Fratila O, Rezi EC, Domnariu C, Deac M. Effects of lovastatin and pentoxyphyllin in nonalcoholic steatohepatitis. Hepatogastroenterology. 2009;56:1117-21.
-
(2009)
Hepatogastroenterology
, vol.56
, pp. 1117-1121
-
-
Mihaila, R.G.1
Nedelcu, L.2
Fratila, O.3
Rezi, E.C.4
Domnariu, C.5
Deac, M.6
-
56
-
-
33646553912
-
A pilot study of atorvastatin treatment in dyslipemid, non-alcoholic fatty liver patients
-
16696815
-
Gomez-Dominguez E, Gisbert JP, Moreno-Monteagudo JA, Garcia-Buey L, Moreno-Otero R. A pilot study of atorvastatin treatment in dyslipemid, non-alcoholic fatty liver patients. Aliment Pharmacol Ther. 2006;23:1643-7.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 1643-1647
-
-
Gomez-Dominguez, E.1
Gisbert, J.P.2
Moreno-Monteagudo, J.A.3
Garcia-Buey, L.4
Moreno-Otero, R.5
-
57
-
-
0347917155
-
Ursodeoxycholic acid and atorvastatin in the treatment of nonalcoholic steatohepatitis
-
14679419
-
Kiyici M, Gulten M, Gurel S, Nak SG, Dolar E, Savci G, Adim SB, Yerci O, Memik F. Ursodeoxycholic acid and atorvastatin in the treatment of nonalcoholic steatohepatitis. Can J Gastroenterol. 2003;17:713-8.
-
(2003)
Can J Gastroenterol
, vol.17
, pp. 713-718
-
-
Kiyici, M.1
Gulten, M.2
Gurel, S.3
Nak, S.G.4
Dolar, E.5
Savci, G.6
Adim, S.B.7
Yerci, O.8
Memik, F.9
-
58
-
-
75149137084
-
Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease
-
Abel T, Feher J, Dinya E, Eldin MG, Kovacs A. Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease. Med Sci Monit. 2009;15:S6-11.
-
(2009)
Med Sci Monit
, vol.15
-
-
Abel, T.1
Feher, J.2
Dinya, E.3
Eldin, M.G.4
Kovacs, A.5
-
59
-
-
34047271926
-
Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study
-
Georgescuand EF, Georgescu M. Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study. J Gastrointest Liver Dis. 2007;16:39-46.
-
(2007)
J Gastrointest Liver Dis
, vol.16
, pp. 39-46
-
-
Georgescuand, E.F.1
Georgescu, M.2
-
60
-
-
79959228507
-
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin
-
Samyand W, Hassanian MA. Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin. Arab J Gastroenterol. 2011;12:80-5.
-
(2011)
Arab J Gastroenterol
, vol.12
, pp. 80-85
-
-
Samyand, W.1
Hassanian, M.A.2
-
61
-
-
20444371945
-
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
-
15928087
-
Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HJ, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'Neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci USA. 2005;102:8132-7.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8132-8137
-
-
Garcia-Calvo, M.1
Lisnock, J.2
Bull, H.G.3
Hawes, B.E.4
Burnett, D.A.5
Braun, M.P.6
Crona, J.H.7
Davis, H.J.8
Dean, D.C.9
Detmers, P.A.10
Graziano, M.P.11
Hughes, M.12
Macintyre, D.E.13
Ogawa, A.14
O'Neill, K.A.15
Iyer, S.P.16
Shevell, D.E.17
Smith, M.M.18
Tang, Y.S.19
Makarewicz, A.M.20
Ujjainwalla, F.21
Altmann, S.W.22
Chapman, K.T.23
Thornberry, N.A.24
more..
-
62
-
-
0142043930
-
Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor
-
Jeuand L, Cheng JW. Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor. Clin Ther. 2003;25:2352-87.
-
(2003)
Clin Ther
, vol.25
, pp. 2352-2387
-
-
Jeuand, L.1
Cheng, J.W.2
-
63
-
-
77954366025
-
Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study
-
20412324
-
Yoneda M, Fujita K, Nozaki Y, Endo H, Takahashi H, Hosono K, Suzuki K, Mawatari H, Kirikoshi H, Inamori M, Saito S, Iwasaki T, Terauchi Y, Kubota K, Maeyama S, Nakajima A. Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: an open-label, pilot study. Hepatol Res. 2010;40:566-73.
-
(2010)
Hepatol Res
, vol.40
, pp. 566-573
-
-
Yoneda, M.1
Fujita, K.2
Nozaki, Y.3
Endo, H.4
Takahashi, H.5
Hosono, K.6
Suzuki, K.7
Mawatari, H.8
Kirikoshi, H.9
Inamori, M.10
Saito, S.11
Iwasaki, T.12
Terauchi, Y.13
Kubota, K.14
Maeyama, S.15
Nakajima, A.16
-
64
-
-
84891820153
-
Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in fatty liver Shionogi mouse
-
23510093
-
Wang X, Sugimoto K, Fujisawa T, Shindo N, Minato S, Kamada Y, Hamano M, Ohishi M, Ikegami H, Rakugi H. Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in fatty liver Shionogi mouse. Hepatol Res. 2014;44:102-13.
-
(2014)
Hepatol Res
, vol.44
, pp. 102-113
-
-
Wang, X.1
Sugimoto, K.2
Fujisawa, T.3
Shindo, N.4
Minato, S.5
Kamada, Y.6
Hamano, M.7
Ohishi, M.8
Ikegami, H.9
Rakugi, H.10
-
65
-
-
84884300669
-
The liver X receptor: A master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease
-
23542537
-
Ducheix S, Montagner A, Theodorou V, Ferrier L, Guillou H. The liver X receptor: a master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease. Biochem Pharmacol. 2013;86:96-105.
-
(2013)
Biochem Pharmacol
, vol.86
, pp. 96-105
-
-
Ducheix, S.1
Montagner, A.2
Theodorou, V.3
Ferrier, L.4
Guillou, H.5
-
66
-
-
33644651160
-
Liver X receptors as integrators of metabolic and inflammatory signaling
-
Zelcerand N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest. 2006;116:607-14.
-
(2006)
J Clin Invest
, vol.116
, pp. 607-614
-
-
Zelcerand, N.1
Tontonoz, P.2
-
67
-
-
36348932064
-
Liver X receptor and farnesoid X receptor as therapeutic targets
-
18047847
-
Rader DJ. Liver X receptor and farnesoid X receptor as therapeutic targets. Am J Cardiol. 2007;100:n15-9.
-
(2007)
Am J Cardiol
, vol.100
-
-
Rader, D.J.1
-
68
-
-
44849141405
-
Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men
-
18323516
-
Rigamonti E, Chinetti-Gbaguidiand G, Staels B. Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men. Arterioscler Thromb Vasc Biol. 2008;28:1050-9.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1050-1059
-
-
Rigamonti, E.1
Chinetti-Gbaguidiand, G.2
Staels, B.3
-
69
-
-
34547624651
-
Mouse models for atherosclerosis and pharmaceutical modifiers
-
17541027
-
Zadelaar S, Kleemann R, Verschuren L, de Vries-Van DWJ, van der Hoorn J, Princen HM, Kooistra T. Mouse models for atherosclerosis and pharmaceutical modifiers. Arterioscler Thromb Vasc Biol. 2007;27:1706-21.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1706-1721
-
-
Zadelaar, S.1
Kleemann, R.2
Verschuren, L.3
De Vries-Van, D.W.J.4
Van Der Hoorn, J.5
Princen, H.M.6
Kooistra, T.7
-
70
-
-
33845922351
-
Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis
-
16950764
-
Spann NJ, Kang S, Li AC, Chen AZ, Newberry EP, Davidson NO, Hui ST, Davis RA. Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis. J Biol Chem. 2006;281:33066-77.
-
(2006)
J Biol Chem
, vol.281
, pp. 33066-33077
-
-
Spann, N.J.1
Kang, S.2
Li, A.C.3
Chen, A.Z.4
Newberry, E.P.5
Davidson, N.O.6
Hui, S.T.7
Davis, R.A.8
-
71
-
-
80052765066
-
Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease
-
22977624
-
Higuchi N, Kato M, Tanaka M, Miyazaki M, Takao S, Kohjima M, Kotoh K, Enjoji M, Nakamuta M, Takayanagi R. Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease. Exp Ther Med. 2011;2:1077-81.
-
(2011)
Exp Ther Med
, vol.2
, pp. 1077-1081
-
-
Higuchi, N.1
Kato, M.2
Tanaka, M.3
Miyazaki, M.4
Takao, S.5
Kohjima, M.6
Kotoh, K.7
Enjoji, M.8
Nakamuta, M.9
Takayanagi, R.10
-
72
-
-
84863700580
-
Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology
-
22705711
-
Liu Q, Siloto RM, Lehner R, Stone SJ, Weselake RJ. Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology. Prog Lipid Res. 2012;51:350-77.
-
(2012)
Prog Lipid Res
, vol.51
, pp. 350-377
-
-
Liu, Q.1
Siloto, R.M.2
Lehner, R.3
Stone, S.J.4
Weselake, R.J.5
-
73
-
-
14744304497
-
Inhibition of triglyceride synthesis as a treatment strategy for obesity: Lessons from DGAT1-deficient mice
-
Chenand HC, Farese RJ. Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler Thromb Vasc Biol. 2005;25:482-6.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 482-486
-
-
Chenand, H.C.1
Farese, R.J.2
-
74
-
-
33646128507
-
Enhancing energy and glucose metabolism by disrupting triglyceride synthesis: Lessons from mice lacking DGAT1
-
Chen HC. Enhancing energy and glucose metabolism by disrupting triglyceride synthesis: lessons from mice lacking DGAT1. Nutr Metab (Lond). 2006;3:10.
-
(2006)
Nutr Metab (Lond)
, vol.3
, pp. 10
-
-
Chen, H.C.1
-
75
-
-
23044450772
-
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
-
16001399
-
Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, Song XZ, Kelly S, Chen S, McKay R, Monia BP, Bhanot S. Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology. 2005;42:362-71.
-
(2005)
Hepatology
, vol.42
, pp. 362-371
-
-
Yu, X.X.1
Murray, S.F.2
Pandey, S.K.3
Booten, S.L.4
Bao, D.5
Song, X.Z.6
Kelly, S.7
Chen, S.8
McKay, R.9
Monia, B.P.10
Bhanot, S.11
-
76
-
-
84860284295
-
Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing
-
22355095
-
Tep S, Mihaila R, Freeman A, Pickering V, Huynh F, Tadin-Strapps M, Stracks A, Hubbard B, Caldwell J, Flanagan WM, Kuklin NA, Ason B. Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing. J Lipid Res. 2012;53:859-67.
-
(2012)
J Lipid Res
, vol.53
, pp. 859-867
-
-
Tep, S.1
Mihaila, R.2
Freeman, A.3
Pickering, V.4
Huynh, F.5
Tadin-Strapps, M.6
Stracks, A.7
Hubbard, B.8
Caldwell, J.9
Flanagan, W.M.10
Kuklin, N.A.11
Ason, B.12
-
77
-
-
5644266305
-
Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: Potential role in the regulation of apolipoprotein B secretion
-
15380446
-
Casaschi A, Rubio BK, Maiyoh GK, Theriault AG. Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion. Atherosclerosis. 2004;176:247-53.
-
(2004)
Atherosclerosis
, vol.176
, pp. 247-253
-
-
Casaschi, A.1
Rubio, B.K.2
Maiyoh, G.K.3
Theriault, A.G.4
-
78
-
-
84859157277
-
Roles of PPARs in NAFLD: Potential therapeutic targets
-
22056763
-
Tailleux A, Woutersand K, Staels B. Roles of PPARs in NAFLD: potential therapeutic targets. Biochim Biophys Acta. 2012;1821:809-18.
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 809-818
-
-
Tailleux, A.1
Woutersand, K.2
Staels, B.3
-
79
-
-
33645032081
-
Peroxisome proliferator-activated receptor alpha plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors
-
Motojimaand K, Hirai T. Peroxisome proliferator-activated receptor alpha plays a vital role in inducing a detoxification system against plant compounds with crosstalk with other xenobiotic nuclear receptors. FEBS J. 2006;273:292-300.
-
(2006)
FEBS J
, vol.273
, pp. 292-300
-
-
Motojimaand, K.1
Hirai, T.2
-
80
-
-
33748422385
-
Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha
-
16828988
-
Kane CD, Franconeand OL, Stevens KA. Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha. Gene. 2006;380:84-94.
-
(2006)
Gene
, vol.380
, pp. 84-94
-
-
Kane, C.D.1
Franconeand, O.L.2
Stevens, K.A.3
-
81
-
-
0038643427
-
Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice
-
12829994
-
Ip E, Farrell GC, Robertson G, Hall P, Kirsch R, Leclercq I. Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology. 2003;38:123-32.
-
(2003)
Hepatology
, vol.38
, pp. 123-132
-
-
Ip, E.1
Farrell, G.C.2
Robertson, G.3
Hall, P.4
Kirsch, R.5
Leclercq, I.6
-
82
-
-
33646812161
-
Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver
-
16762007
-
Harano Y, Yasui K, Toyama T, Nakajima T, Mitsuyoshi H, Mimani M, Hirasawa T, Itoh Y, Okanoue T. Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. Liver Int. 2006;26:613-20.
-
(2006)
Liver Int
, vol.26
, pp. 613-620
-
-
Harano, Y.1
Yasui, K.2
Toyama, T.3
Nakajima, T.4
Mitsuyoshi, H.5
Mimani, M.6
Hirasawa, T.7
Itoh, Y.8
Okanoue, T.9
-
83
-
-
33244494398
-
PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes
-
16282640
-
Edvardsson U, Ljungberg A, Linden D, William-Olsson L, Peilot-Sjogren H, Ahnmark A, Oscarsson J. PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes. J Lipid Res. 2006;47:329-40.
-
(2006)
J Lipid Res
, vol.47
, pp. 329-340
-
-
Edvardsson, U.1
Ljungberg, A.2
Linden, D.3
William-Olsson, L.4
Peilot-Sjogren, H.5
Ahnmark, A.6
Oscarsson, J.7
-
84
-
-
0021276830
-
Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man
-
Kesaniemiand YA, Grundy SM. Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man. JAMA. 1984;251:2241-6.
-
(1984)
JAMA
, vol.251
, pp. 2241-2246
-
-
Kesaniemiand, Y.A.1
Grundy, S.M.2
-
85
-
-
0024245703
-
Effects of ciprofibrate and fenofibrate on liver lipids and lipoprotein synthesis in normo- and hyperlipidemic rats
-
3240333
-
Petit D, Bonnefis MT, Rey C, Infante R. Effects of ciprofibrate and fenofibrate on liver lipids and lipoprotein synthesis in normo- and hyperlipidemic rats. Atherosclerosis. 1988;74:215-25.
-
(1988)
Atherosclerosis
, vol.74
, pp. 215-225
-
-
Petit, D.1
Bonnefis, M.T.2
Rey, C.3
Infante, R.4
-
86
-
-
0037025390
-
WY14, 643, a peroxisome proliferator-activated receptor α (PPARα) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice
-
11994294
-
Chou CJ, Haluzik M, Gregory C, Dietz KR, Vinson C, Gavrilova O, Reitman ML. WY14, 643, a peroxisome proliferator-activated receptor α (PPARα) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice. J Biol Chem. 2002;277:24484-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 24484-24489
-
-
Chou, C.J.1
Haluzik, M.2
Gregory, C.3
Dietz, K.R.4
Vinson, C.5
Gavrilova, O.6
Reitman, M.L.7
-
87
-
-
3042791281
-
Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver
-
15200495
-
Akbiyik F, Cinar K, Demirpence E, Ozsullu T, Tunca R, Haziroglu R, Yurdaydin C, Uzunalimoglu O, Bozkaya H. Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver. Eur J Clin Invest. 2004;34:429-35.
-
(2004)
Eur J Clin Invest
, vol.34
, pp. 429-435
-
-
Akbiyik, F.1
Cinar, K.2
Demirpence, E.3
Ozsullu, T.4
Tunca, R.5
Haziroglu, R.6
Yurdaydin, C.7
Uzunalimoglu, O.8
Bozkaya, H.9
-
88
-
-
21644436821
-
Peroxisome proliferator-activated receptor (PPAR)-alpha: A pharmacological target with a promising future
-
15497675
-
van Raalte DH, Li M, Pritchard PH, Wasan KM. Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future. Pharm Res. 2004;21:1531-8.
-
(2004)
Pharm Res
, vol.21
, pp. 1531-1538
-
-
Van Raalte, D.H.1
Li, M.2
Pritchard, P.H.3
Wasan, K.M.4
-
89
-
-
33747584151
-
Improvement of insulin sensitivity after peroxisome proliferator- activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels
-
16740970
-
Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M. Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels. Endocrinology. 2006;147:4517-24.
-
(2006)
Endocrinology
, vol.147
, pp. 4517-4524
-
-
Haluzik, M.M.1
Lacinova, Z.2
Dolinkova, M.3
Haluzikova, D.4
Housa, D.5
Horinek, A.6
Vernerova, Z.7
Kumstyrova, T.8
Haluzik, M.9
-
90
-
-
33645891166
-
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
-
16574099
-
Nagasawa T, Inada Y, Nakano S, Tamura T, Takahashi T, Maruyama K, Yamazaki Y, Kuroda J, Shibata N. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. Eur J Pharmacol. 2006;536:182-91.
-
(2006)
Eur J Pharmacol
, vol.536
, pp. 182-191
-
-
Nagasawa, T.1
Inada, Y.2
Nakano, S.3
Tamura, T.4
Takahashi, T.5
Maruyama, K.6
Yamazaki, Y.7
Kuroda, J.8
Shibata, N.9
-
91
-
-
25444467483
-
Short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation
-
16177634
-
Nakamuta M, Morizono S, Soejima Y, Yoshizumi T, Aishima S, Takasugi S, Yoshimitsu K, Enjoji M, Kotoh K, Taketomi A, Uchiyama H, Shimada M, Nawata H, Maehara Y. Short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation. Transplantation. 2005;80:608-12.
-
(2005)
Transplantation
, vol.80
, pp. 608-612
-
-
Nakamuta, M.1
Morizono, S.2
Soejima, Y.3
Yoshizumi, T.4
Aishima, S.5
Takasugi, S.6
Yoshimitsu, K.7
Enjoji, M.8
Kotoh, K.9
Taketomi, A.10
Uchiyama, H.11
Shimada, M.12
Nawata, H.13
Maehara, Y.14
-
92
-
-
33745501159
-
Saying "yes" to obese living liver donors: Short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation
-
16721781
-
Perkins JD. Saying "Yes" to obese living liver donors: short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation. Liver Transpl. 2006;12:1012-3.
-
(2006)
Liver Transpl
, vol.12
, pp. 1012-1013
-
-
Perkins, J.D.1
-
93
-
-
38749085998
-
A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease
-
18261709
-
Fernandez-Miranda C, Perez-Carreras M, Colina F, Lopez-Alonso G, Vargas C, Solis-Herruzo JA. A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease. Dig Liver Dis. 2008;40:200-5.
-
(2008)
Dig Liver Dis
, vol.40
, pp. 200-205
-
-
Fernandez-Miranda, C.1
Perez-Carreras, M.2
Colina, F.3
Lopez-Alonso, G.4
Vargas, C.5
Solis-Herruzo, J.A.6
-
94
-
-
67649829768
-
Nonalcoholic hepatic steatosis in Zucker diabetic rats: Spontaneous evolution and effects of metformin and fenofibrate
-
Forcheron F, Abdallah P, Basset A, Del CP, Haffar G, Beylot M. Nonalcoholic hepatic steatosis in Zucker diabetic rats: spontaneous evolution and effects of metformin and fenofibrate. Obesity (Silver Spring). 2009;17:1381-9.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1381-1389
-
-
Forcheron, F.1
Abdallah, P.2
Basset, A.3
Del, C.P.4
Haffar, G.5
Beylot, M.6
-
95
-
-
33646192257
-
Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice
-
16477380
-
Srivastava RA, Jahagirdar R, Azhar S, Sharma S, Bisgaier CL. Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. Mol Cell Biochem. 2006;285:35-50.
-
(2006)
Mol Cell Biochem
, vol.285
, pp. 35-50
-
-
Srivastava, R.A.1
Jahagirdar, R.2
Azhar, S.3
Sharma, S.4
Bisgaier, C.L.5
-
96
-
-
0032776856
-
A controlled trial of gemfibrozil in the treatment of patients with nonalcoholic steatohepatitis
-
10453959
-
Basaranoglu M, Acbayand O, Sonsuz A. A controlled trial of gemfibrozil in the treatment of patients with nonalcoholic steatohepatitis. J Hepatol. 1999;31:384.
-
(1999)
J Hepatol
, vol.31
, pp. 384
-
-
Basaranoglu, M.1
Acbayand, O.2
Sonsuz, A.3
-
97
-
-
84933047295
-
Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: A pilot study
-
8675165
-
Laurin J, Lindor KD, Crippin JS, Gossard A, Gores GJ, Ludwig J, Rakela J, McGill DB. Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology. 1996;23:1464-7.
-
(1996)
Hepatology
, vol.23
, pp. 1464-1467
-
-
Laurin, J.1
Lindor, K.D.2
Crippin, J.S.3
Gossard, A.4
Gores, G.J.5
Ludwig, J.6
Rakela, J.7
McGill, D.B.8
-
98
-
-
84885910586
-
Antioxidant therapy in nonalcoholic steatohepatitis
-
23227320
-
Al-Busafi SA, Bhat M, Wong P, Ghali P, Deschenes M. Antioxidant therapy in nonalcoholic steatohepatitis. Hepat Res Treat. 2012;2012:947575.
-
(2012)
Hepat Res Treat
, vol.2012
, pp. 947575
-
-
Al-Busafi, S.A.1
Bhat, M.2
Wong, P.3
Ghali, P.4
Deschenes, M.5
-
99
-
-
27644510537
-
Review article: Role of oxidative stress in the progression of non-alcoholic steatosis
-
16225478
-
Albano E, Mottaran E, Occhino G, Reale E, Vidali M. Review article: role of oxidative stress in the progression of non-alcoholic steatosis. Aliment Pharmacol Ther. 2005;22(suppl 2):71-3.
-
(2005)
Aliment Pharmacol Ther
, vol.22
, Issue.SUPPL. 2
, pp. 71-73
-
-
Albano, E.1
Mottaran, E.2
Occhino, G.3
Reale, E.4
Vidali, M.5
-
100
-
-
84877039529
-
Nonalcoholic fatty liver disease: Current issues and novel treatment approaches
-
23329465
-
Lomonaco R, Sunny NE, Bril F, Cusi K. Nonalcoholic fatty liver disease: current issues and novel treatment approaches. Drugs. 2013;73:1-14.
-
(2013)
Drugs
, vol.73
, pp. 1-14
-
-
Lomonaco, R.1
Sunny, N.E.2
Bril, F.3
Cusi, K.4
-
102
-
-
84881351498
-
Antioxidant therapy and drugs interfering with lipid metabolism: Could they be effective in NAFLD patients?
-
23394094
-
Musso G, Antyand R, Petta S. Antioxidant therapy and drugs interfering with lipid metabolism: could they be effective in NAFLD patients? Curr Pharm Des. 2013;19:5297-313.
-
(2013)
Curr Pharm des
, vol.19
, pp. 5297-5313
-
-
Musso, G.1
Antyand, R.2
Petta, S.3
-
104
-
-
70350627681
-
Antioxidants vitamin e and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice
-
19606393
-
Nan YM, Wu WJ, Fu N, Liang BL, Wang RQ, Li LX, Zhao SX, Zhao JM, Yu J. Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. Scand J Gastroenterol. 2009;44:1121-31.
-
(2009)
Scand J Gastroenterol
, vol.44
, pp. 1121-1131
-
-
Nan, Y.M.1
Wu, W.J.2
Fu, N.3
Liang, B.L.4
Wang, R.Q.5
Li, L.X.6
Zhao, S.X.7
Zhao, J.M.8
Yu, J.9
-
105
-
-
70349332736
-
Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis
-
19578790
-
Phung N, Pera N, Farrell G, Leclercq I, Hou JY, George J. Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. Int J Mol Med. 2009;24:171-80.
-
(2009)
Int J Mol Med
, vol.24
, pp. 171-180
-
-
Phung, N.1
Pera, N.2
Farrell, G.3
Leclercq, I.4
Hou, J.Y.5
George, J.6
-
106
-
-
78249259701
-
Dietary alpha- and gamma-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and inflammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis
-
20138495
-
Chung MY, Yeung SF, Park HJ, Volek JS, Bruno RS. Dietary alpha- and gamma-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and inflammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis. J Nutr Biochem. 2010;21:1200-6.
-
(2010)
J Nutr Biochem
, vol.21
, pp. 1200-1206
-
-
Chung, M.Y.1
Yeung, S.F.2
Park, H.J.3
Volek, J.S.4
Bruno, R.S.5
-
107
-
-
34548319072
-
Subcutaneous vitamin e ameliorates liver injury in an in vivo model of steatocholestasis
-
17659596
-
Soden JS, Devereaux MW, Haas JE, Gumpricht E, Dahl R, Gralla J, Traber MG, Sokol RJ. Subcutaneous vitamin E ameliorates liver injury in an in vivo model of steatocholestasis. Hepatology. 2007;46:485-95.
-
(2007)
Hepatology
, vol.46
, pp. 485-495
-
-
Soden, J.S.1
Devereaux, M.W.2
Haas, J.E.3
Gumpricht, E.4
Dahl, R.5
Gralla, J.6
Traber, M.G.7
Sokol, R.J.8
-
108
-
-
67349163719
-
Effect of alpha-tocopherol on carbon tetrachloride intoxication in the rat liver
-
19066852
-
Iida C, Fujii K, Koga E, Washino Y, Kitamura Y, Ichi I, Abe K, Matsura T, Kojo S. Effect of alpha-tocopherol on carbon tetrachloride intoxication in the rat liver. Arch Toxicol. 2009;83:477-83.
-
(2009)
Arch Toxicol
, vol.83
, pp. 477-483
-
-
Iida, C.1
Fujii, K.2
Koga, E.3
Washino, Y.4
Kitamura, Y.5
Ichi, I.6
Abe, K.7
Matsura, T.8
Kojo, S.9
-
109
-
-
33947400987
-
Effects of vitamin e treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: Results of a pilot study
-
17388862
-
Yakaryilmaz F, Guliter S, Savas B, Erdem O, Ersoy R, Erden E, Akyol G, Bozkaya H, Ozenirler S. Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. Intern Med J. 2007;37:229-35.
-
(2007)
Intern Med J
, vol.37
, pp. 229-235
-
-
Yakaryilmaz, F.1
Guliter, S.2
Savas, B.3
Erdem, O.4
Ersoy, R.5
Erden, E.6
Akyol, G.7
Bozkaya, H.8
Ozenirler, S.9
-
110
-
-
3142634597
-
Vitamin e treatment in pediatric obesity-related liver disease: A randomized study
-
14676594
-
Vajro P, Mandato C, Franzese A, Ciccimarra E, Lucariello S, Savoia M, Capuano G, Migliaro F. Vitamin E treatment in pediatric obesity-related liver disease: a randomized study. J Pediatr Gastroenterol Nutr. 2004;38:48-55.
-
(2004)
J Pediatr Gastroenterol Nutr
, vol.38
, pp. 48-55
-
-
Vajro, P.1
Mandato, C.2
Franzese, A.3
Ciccimarra, E.4
Lucariello, S.5
Savoia, M.6
Capuano, G.7
Migliaro, F.8
-
111
-
-
0034799895
-
Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: A pilot study
-
11564008
-
Hasegawa T, Yoneda M, Nakamura K, Makino I, Terano A. Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther. 2001;15:1667-72.
-
(2001)
Aliment Pharmacol Ther
, vol.15
, pp. 1667-1672
-
-
Hasegawa, T.1
Yoneda, M.2
Nakamura, K.3
Makino, I.4
Terano, A.5
-
112
-
-
84858622244
-
Ursodeoxycholic acid with vitamin e in patients with nonalcoholic steatohepatitis: Long-term results
-
22154224
-
Pietu F, Guillaud O, Walter T, Vallin M, Hervieu V, Scoazec JY, Dumortier J. Ursodeoxycholic acid with vitamin E in patients with nonalcoholic steatohepatitis: long-term results. Clin Res Hepatol Gastroenterol. 2012;36:146-55.
-
(2012)
Clin Res Hepatol Gastroenterol
, vol.36
, pp. 146-155
-
-
Pietu, F.1
Guillaud, O.2
Walter, T.3
Vallin, M.4
Hervieu, V.5
Scoazec, J.Y.6
Dumortier, J.7
-
113
-
-
33845336554
-
Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis
-
17162245
-
Dufour JF, Oneta CM, Gonvers JJ, Bihl F, Cerny A, Cereda JM, Zala JF, Helbling B, Steuerwald M, Zimmermann A. Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2006;4:1537-43.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 1537-1543
-
-
Dufour, J.F.1
Oneta, C.M.2
Gonvers, J.J.3
Bihl, F.4
Cerny, A.5
Cereda, J.M.6
Zala, J.F.7
Helbling, B.8
Steuerwald, M.9
Zimmermann, A.10
-
114
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
20427778
-
Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010;362:1675-85.
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
McCullough, A.4
Diehl, A.M.5
Bass, N.M.6
Neuschwander-Tetri, B.A.7
Lavine, J.E.8
Tonascia, J.9
Unalp, A.10
Van Natta, M.11
Clark, J.12
Brunt, E.M.13
Kleiner, D.E.14
Hoofnagle, J.H.15
Robuck, P.R.16
-
115
-
-
79955446251
-
Effect of vitamin e or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: The TONIC randomized controlled trial
-
21521847
-
Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Unalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA. 2011;305:1659-68.
-
(2011)
JAMA
, vol.305
, pp. 1659-1668
-
-
Lavine, J.E.1
Schwimmer, J.B.2
Van Natta, M.L.3
Molleston, J.P.4
Murray, K.F.5
Rosenthal, P.6
Abrams, S.H.7
Scheimann, A.O.8
Sanyal, A.J.9
Chalasani, N.10
Tonascia, J.11
Unalp, A.12
Clark, J.M.13
Brunt, E.M.14
Kleiner, D.E.15
Hoofnagle, J.H.16
Robuck, P.R.17
-
116
-
-
2942706241
-
Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
Araya J, Rodrigo R, Videla LA, Thielemann L, Orellana M, Pettinelli P, Poniachik J. Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. Clin Sci (Lond). 2004;106:635-43.
-
(2004)
Clin Sci (Lond)
, vol.106
, pp. 635-643
-
-
Araya, J.1
Rodrigo, R.2
Videla, L.A.3
Thielemann, L.4
Orellana, M.5
Pettinelli, P.6
Poniachik, J.7
-
117
-
-
33646882162
-
Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: A pilot study
-
Cappani M, Callelaand F, Biagini MR. Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study. Aliment Pharmacol. 2006;23:1143-51.
-
(2006)
Aliment Pharmacol
, vol.23
, pp. 1143-1151
-
-
Cappani, M.1
Callelaand, F.2
Biagini, M.R.3
-
118
-
-
38749115791
-
Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease
-
18054848
-
Spadaro L, Magliocco O, Spampinato D, Piro S, Oliveri C, Alagona C, Papa G, Rabuazzo AM, Purrello F. Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease. Dig Liver Dis. 2008;40:194-9.
-
(2008)
Dig Liver Dis
, vol.40
, pp. 194-199
-
-
Spadaro, L.1
Magliocco, O.2
Spampinato, D.3
Piro, S.4
Oliveri, C.5
Alagona, C.6
Papa, G.7
Rabuazzo, A.M.8
Purrello, F.9
-
119
-
-
41349102802
-
Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis
-
18277895
-
Tanaka N, Sano K, Horiuchi A, Tanaka E, Kiyosawa K, Aoyama T. Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis. J Clin Gastroenterol. 2008;42:413-8.
-
(2008)
J Clin Gastroenterol
, vol.42
, pp. 413-418
-
-
Tanaka, N.1
Sano, K.2
Horiuchi, A.3
Tanaka, E.4
Kiyosawa, K.5
Aoyama, T.6
-
120
-
-
78649823911
-
Effects of a 1-year dietary intervention with n-3 polyunsaturated fatty acid-enriched olive oil on non-alcoholic fatty liver disease patients: A preliminary study
-
20465434
-
Sofi F, Giangrandi I, Cesari F, Corsani I, Abbate R, Gensini GF, Casini A. Effects of a 1-year dietary intervention with n-3 polyunsaturated fatty acid-enriched olive oil on non-alcoholic fatty liver disease patients: a preliminary study. Int J Food Sci Nutr. 2010;61:792-802.
-
(2010)
Int J Food Sci Nutr
, vol.61
, pp. 792-802
-
-
Sofi, F.1
Giangrandi, I.2
Cesari, F.3
Corsani, I.4
Abbate, R.5
Gensini, G.F.6
Casini, A.7
-
121
-
-
63449137594
-
Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia
-
19009658
-
Zhu FS, Liu S, Chen XM, Huang ZG, Zhang DW. Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia. World J Gastroenterol. 2008;14:6395-400.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 6395-6400
-
-
Zhu, F.S.1
Liu, S.2
Chen, X.M.3
Huang, Z.G.4
Zhang, D.W.5
-
122
-
-
84924040502
-
ω-3 fatty acids prevent hepatic steatosis, independent of PPAR-α activity, in a murine model of parenteral nutrition-associated liver disease
-
Jun 11 [Epub ahead of print]
-
Prince E, Lazare FB, Treem WR, Xu J, Iqbal J, Pan X, Josekutty J, Walsh M, Anderson V, Hussain MM, Schwarz SM. ω-3 fatty acids prevent hepatic steatosis, independent of PPAR-α activity, in a murine model of parenteral nutrition-associated liver disease. JPEN J Parenter Enteral Nutr. 2013 Jun 11 [Epub ahead of print].
-
(2013)
JPEN J Parenter Enteral Nutr.
-
-
Prince, E.1
Lazare, F.B.2
Treem, W.R.3
Xu, J.4
Iqbal, J.5
Pan, X.6
Josekutty, J.7
Walsh, M.8
Anderson, V.9
Hussain, M.M.10
Schwarz, S.M.11
-
123
-
-
39149132072
-
Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation
-
17868330
-
Larter CZ, Yeh MM, Cheng J, Williams J, Brown S, Dela PA, Bell-Anderson KS, Farrell GC. Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation. J Gastroenterol Hepatol. 2008;23:267-75.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 267-275
-
-
Larter, C.Z.1
Yeh, M.M.2
Cheng, J.3
Williams, J.4
Brown, S.5
Dela, P.A.6
Bell-Anderson, K.S.7
Farrell, G.C.8
-
124
-
-
46449124024
-
Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol
-
18049900
-
Merat S, Aduli M, Kazemi R, Sotoudeh M, Sedighi N, Sohrabi M, Malekzadeh R. Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol. Dig Dis Sci. 2008;53:2246-50.
-
(2008)
Dig Dis Sci
, vol.53
, pp. 2246-2250
-
-
Merat, S.1
Aduli, M.2
Kazemi, R.3
Sotoudeh, M.4
Sedighi, N.5
Sohrabi, M.6
Malekzadeh, R.7
-
125
-
-
0037383865
-
Probucol in the treatment of non-alcoholic steatohepatitis: A double-blind randomized controlled study
-
12663231
-
Merat S, Malekzadeh R, Sohrabi MR, Sotoudeh M, Rakhshani N, Sohrabpour AA, Naserimoghadam S. Probucol in the treatment of non-alcoholic steatohepatitis: a double-blind randomized controlled study. J Hepatol. 2003;38:414-8.
-
(2003)
J Hepatol
, vol.38
, pp. 414-418
-
-
Merat, S.1
Malekzadeh, R.2
Sohrabi, M.R.3
Sotoudeh, M.4
Rakhshani, N.5
Sohrabpour, A.A.6
Naserimoghadam, S.7
-
126
-
-
84898776728
-
Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study
-
Apr 17 [Epub ahead of print]
-
Ishitobi T, Hyogo H, Tokumo H, Arihiro K, Chayama K. Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: an open-label pilot study. Hepatol Res. 2013 Apr 17 [Epub ahead of print].
-
(2013)
Hepatol Res.
-
-
Ishitobi, T.1
Hyogo, H.2
Tokumo, H.3
Arihiro, K.4
Chayama, K.5
-
127
-
-
70350568228
-
Where are we with probucol: A new life for an old drug?
-
Yamashitaand S, Matsuzawa Y. Where are we with probucol: a new life for an old drug? Atherosclerosis. 2009;207:16-23.
-
(2009)
Atherosclerosis
, vol.207
, pp. 16-23
-
-
Yamashitaand, S.1
Matsuzawa, Y.2
-
128
-
-
34249829862
-
Efficacy and safety of dirlotapide in the management of obese dogs evaluated in two placebo-controlled, masked clinical studies in North America
-
17567518
-
Wren JA, Ramudo AA, Campbell SL, King VL, Eagleson JS, Gossellin J, Sunderland SJ. Efficacy and safety of dirlotapide in the management of obese dogs evaluated in two placebo-controlled, masked clinical studies in North America. J Vet Pharmacol Ther. 2007;30(suppl 1):81-9.
-
(2007)
J Vet Pharmacol Ther
, vol.30
, Issue.SUPPL. 1
, pp. 81-89
-
-
Wren, J.A.1
Ramudo, A.A.2
Campbell, S.L.3
King, V.L.4
Eagleson, J.S.5
Gossellin, J.6
Sunderland, S.J.7
-
129
-
-
34249781964
-
An evaluation of dirlotapide to reduce body weight of client-owned dogs in two placebo-controlled clinical studies in Europe
-
17567517
-
Gossellin J, McKelvie J, Sherington J, Wren JA, Eagleson JS, Rowan TG, Sunderland SJ. An evaluation of dirlotapide to reduce body weight of client-owned dogs in two placebo-controlled clinical studies in Europe. J Vet Pharmacol Ther. 2007;30(suppl 1):73-80.
-
(2007)
J Vet Pharmacol Ther
, vol.30
, Issue.SUPPL. 1
, pp. 73-80
-
-
Gossellin, J.1
McKelvie, J.2
Sherington, J.3
Wren, J.A.4
Eagleson, J.S.5
Rowan, T.G.6
Sunderland, S.J.7
-
130
-
-
79956202758
-
A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: Biochemical, pharmacodynamic, pharmacokinetic, and safety profile
-
21406547
-
Kim E, Campbell S, Schueller O, Wong E, Cole B, Kuo J, Ellis J, Ferkany J, Sweetnam P. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther. 2011;337:775-85.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 775-785
-
-
Kim, E.1
Campbell, S.2
Schueller, O.3
Wong, E.4
Cole, B.5
Kuo, J.6
Ellis, J.7
Ferkany, J.8
Sweetnam, P.9
-
131
-
-
78751531122
-
Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4- [(4'-trifluoromethylbiphenyl-2-carbonyl)amino]p henyl}acetyloxymethyl)-2- phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein
-
20974698
-
Mera Y, Odani N, Kawai T, Hata T, Suzuki M, Hagiwara A, Katsushima T, Kakutani M. Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl- 4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]p henyl}acetyloxymethyl)-2- phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein. J Pharmacol Exp Ther. 2011;336:321-7.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 321-327
-
-
Mera, Y.1
Odani, N.2
Kawai, T.3
Hata, T.4
Suzuki, M.5
Hagiwara, A.6
Katsushima, T.7
Kakutani, M.8
-
132
-
-
26844580001
-
JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
-
16188040
-
Aggarwal D, West KL, Zern TL, Shrestha S, Vergara-Jimenez M, Fernandez ML. JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs. BMC Cardiovasc Disord. 2005;5:30.
-
(2005)
BMC Cardiovasc Disord
, vol.5
, pp. 30
-
-
Aggarwal, D.1
West, K.L.2
Zern, T.L.3
Shrestha, S.4
Vergara-Jimenez, M.5
Fernandez, M.L.6
-
133
-
-
84874289874
-
Non-alcoholic fatty liver disease and insulin resistance: From bench to bedside
-
23266468
-
Gariani K, Philippeand J, Jornayvaz FR. Non-alcoholic fatty liver disease and insulin resistance: from bench to bedside. Diabetes Metab. 2013;39:16-26.
-
(2013)
Diabetes Metab
, vol.39
, pp. 16-26
-
-
Gariani, K.1
Philippeand, J.2
Jornayvaz, F.R.3
-
134
-
-
84877854022
-
Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease
-
23666091
-
Gaggini M, Morelli M, Buzzigoli E, DeFronzo RA, Bugianesi E, Gastaldelli A. Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease. Nutrients. 2013;5:1544-60.
-
(2013)
Nutrients
, vol.5
, pp. 1544-1560
-
-
Gaggini, M.1
Morelli, M.2
Buzzigoli, E.3
Defronzo, R.A.4
Bugianesi, E.5
Gastaldelli, A.6
-
135
-
-
73949147212
-
Insulin sensitizers in nonalcoholic fatty liver disease and steatohepatitis: Current status
-
19921118
-
Stein LL, Dongand MH, Loomba R. Insulin sensitizers in nonalcoholic fatty liver disease and steatohepatitis: current status. Adv Ther. 2009;26:893-907.
-
(2009)
Adv Ther
, vol.26
, pp. 893-907
-
-
Stein, L.L.1
Dongand, M.H.2
Loomba, R.3
-
136
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
7623903
-
Stumvoll M, Nurjhan N, Perriello G, Dailey G, Gerich JE. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med. 1995;333:550-4.
-
(1995)
N Engl J Med
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
Dailey, G.4
Gerich, J.E.5
-
137
-
-
84864062799
-
Overview of metformin: Special focus on metformin extended release
-
Aliand S, Fonseca V. Overview of metformin: special focus on metformin extended release. Expert Opin Pharmacother. 2012;13:1797-805.
-
(2012)
Expert Opin Pharmacother
, vol.13
, pp. 1797-1805
-
-
Aliand, S.1
Fonseca, V.2
-
138
-
-
1642296465
-
Metformin in the treatment of patients with non-alcoholic steatohepatitis
-
14987322
-
Uygun A, Kadayifci A, Isik AT, Ozgurtas T, Deveci S, Tuzun A, Yesilova Z, Gulsen M, Dagalp K. Metformin in the treatment of patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2004;19:537-44.
-
(2004)
Aliment Pharmacol Ther
, vol.19
, pp. 537-544
-
-
Uygun, A.1
Kadayifci, A.2
Isik, A.T.3
Ozgurtas, T.4
Deveci, S.5
Tuzun, A.6
Yesilova, Z.7
Gulsen, M.8
Dagalp, K.9
-
139
-
-
3142670354
-
Metformin in the treatment of non-alcoholic steatohepatitis: A pilot open label trial
-
15225167
-
Nair S, Diehl AM, Wiseman M, Farr GJ, Perrillo RP. Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open label trial. Aliment Pharmacol Ther. 2004;20:23-8.
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 23-28
-
-
Nair, S.1
Diehl, A.M.2
Wiseman, M.3
Farr, G.J.4
Perrillo, R.P.5
-
140
-
-
24144444669
-
Histopathology of pediatric nonalcoholic fatty liver disease
-
16116629
-
Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, Lavine JE. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005;42:641-9.
-
(2005)
Hepatology
, vol.42
, pp. 641-649
-
-
Schwimmer, J.B.1
Behling, C.2
Newbury, R.3
Deutsch, R.4
Nievergelt, C.5
Schork, N.J.6
Lavine, J.E.7
-
141
-
-
33747077203
-
NAFLD in children: A prospective clinical-pathological study and effect of lifestyle advice
-
16871574
-
Nobili V, Marcellini M, Devito R, Ciampalini P, Piemonte F, Comparcola D, Sartorelli MR, Angulo P. NAFLD in children: a prospective clinical-pathological study and effect of lifestyle advice. Hepatology. 2006;44:458-65.
-
(2006)
Hepatology
, vol.44
, pp. 458-465
-
-
Nobili, V.1
Marcellini, M.2
Devito, R.3
Ciampalini, P.4
Piemonte, F.5
Comparcola, D.6
Sartorelli, M.R.7
Angulo, P.8
-
142
-
-
57649229536
-
Clinical trial: Pilot study of metformin for the treatment of non-alcoholic steatohepatitis
-
18945255
-
Loomba R, Lutchman G, Kleiner DE, Ricks M, Feld JJ, Borg BB, Modi A, Nagabhyru P, Sumner AE, Liang TJ, Hoofnagle JH. Clinical trial: pilot study of metformin for the treatment of non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2009;29:172-82.
-
(2009)
Aliment Pharmacol Ther
, vol.29
, pp. 172-182
-
-
Loomba, R.1
Lutchman, G.2
Kleiner, D.E.3
Ricks, M.4
Feld, J.J.5
Borg, B.B.6
Modi, A.7
Nagabhyru, P.8
Sumner, A.E.9
Liang, T.J.10
Hoofnagle, J.H.11
-
143
-
-
38049131878
-
Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis
-
18197877
-
de Oliveira CP, Stefano JT, de Siqueira ER, Silva LS, de Campos MD, Lima VM, Furuya CK, Mello ES, Souza FG, Rabello F, Santos TE, Nogueira MA, Caldwell SH, Alves VA, Carrilho FJ. Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis. Hepatol Res. 2008;38:159-65.
-
(2008)
Hepatol Res
, vol.38
, pp. 159-165
-
-
De Oliveira, C.P.1
Stefano, J.T.2
De Siqueira, E.R.3
Silva, L.S.4
De Campos, M.D.5
Lima, V.M.6
Furuya, C.K.7
Mello, E.S.8
Souza, F.G.9
Rabello, F.10
Santos, T.E.11
Nogueira, M.A.12
Caldwell, S.H.13
Alves, V.A.14
Carrilho, F.J.15
-
144
-
-
77955470801
-
Metformin versus dietary treatment in nonalcoholic hepatic steatosis: A randomized study
-
Garinis GA, Fruci B, Mazza A, De Siena M, Abenavoli S, Gulletta E, Ventura V, Greco M, Abenavoli L, Belfiore A. Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study. Int J Obes (Lond). 2010;34:1255-64.
-
(2010)
Int J Obes (Lond)
, vol.34
, pp. 1255-1264
-
-
Garinis, G.A.1
Fruci, B.2
Mazza, A.3
De Siena, M.4
Abenavoli, S.5
Gulletta, E.6
Ventura, V.7
Greco, M.8
Abenavoli, L.9
Belfiore, A.10
-
145
-
-
0026029277
-
Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
-
1900072
-
Landin K, Tengbornand L, Smith U. Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors. J Intern Med. 1991;229:181-7.
-
(1991)
J Intern Med
, vol.229
, pp. 181-187
-
-
Landin, K.1
Tengbornand, L.2
Smith, U.3
-
146
-
-
0029919722
-
Acute sympathoinhibitory actions of metformin in spontaneously hypertensive rats
-
Petersenand JS, DiBona GF. Acute sympathoinhibitory actions of metformin in spontaneously hypertensive rats. Hypertension. 1996;27:619-25.
-
(1996)
Hypertension
, vol.27
, pp. 619-625
-
-
Petersenand, J.S.1
Dibona, G.F.2
-
147
-
-
84862517200
-
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of randomised trials
-
22278337
-
Musso G, Cassader M, Rosina F, Gambino R. Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials. Diabetologia. 2012;55:885-904.
-
(2012)
Diabetologia
, vol.55
, pp. 885-904
-
-
Musso, G.1
Cassader, M.2
Rosina, F.3
Gambino, R.4
-
148
-
-
79959554252
-
The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis
-
Van Wagnerand LB, Rinella ME. The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis. Ther Adv Gastroenterol. 2011;4:249-63.
-
(2011)
Ther Adv Gastroenterol
, vol.4
, pp. 249-263
-
-
Van Wagnerand, L.B.1
Rinella, M.E.2
-
149
-
-
0035120396
-
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis
-
11232700
-
Caldwell SH, Hespenheide EE, Redick JA, Iezzoni JC, Battle EH, Sheppard BL. A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol. 2001;96:519-25.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 519-525
-
-
Caldwell, S.H.1
Hespenheide, E.E.2
Redick, J.A.3
Iezzoni, J.C.4
Battle, E.H.5
Sheppard, B.L.6
-
150
-
-
10744227512
-
Journeys of the circle: A culturally congruent life skills intervention for adolescent Indian drinking
-
12966331
-
Marlatt GA, Larimer ME, Mail PD, Hawkins EH, Cummins LH, Blume AW, Lonczak HS, Burns KM, Chan KK, Cronce JM, La Marr CJ, Radin S, Forquera R, Gonzales R, Tetrick C, Gallion S. Journeys of the circle: a culturally congruent life skills intervention for adolescent Indian drinking. Alcohol Clin Exp Res. 2003;27:1327-9.
-
(2003)
Alcohol Clin Exp Res
, vol.27
, pp. 1327-1329
-
-
Marlatt, G.A.1
Larimer, M.E.2
Mail, P.D.3
Hawkins, E.H.4
Cummins, L.H.5
Blume, A.W.6
Lonczak, H.S.7
Burns, K.M.8
Chan, K.K.9
Cronce, J.M.10
La Marr, C.J.11
Radin, S.12
Forquera, R.13
Gonzales, R.14
Tetrick, C.15
Gallion, S.16
-
151
-
-
3242745192
-
Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
-
15277403
-
Tiikkainen M, Hakkinen AM, Korsheninnikova E, Nyman T, Makimattila S, Yki-Jarvinen H. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes. 2004;53:2169-76.
-
(2004)
Diabetes
, vol.53
, pp. 2169-2176
-
-
Tiikkainen, M.1
Hakkinen, A.M.2
Korsheninnikova, E.3
Nyman, T.4
Makimattila, S.5
Yki-Jarvinen, H.6
-
152
-
-
46349088361
-
Rosiglitazone for nonalcoholic steatohepatitis: One-year results of the randomized placebo-controlled fatty liver improvement with rosiglitazone therapy (FLIRT) trial
-
18503774
-
Ratziu V, Giral P, Jacqueminet S, Charlotte F, Hartemann-Heurtier A, Serfaty L, Podevin P, Lacorte JM, Bernhardt C, Bruckert E, Grimaldi A, Poynard T. Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled fatty liver improvement with rosiglitazone therapy (FLIRT) trial. Gastroenterology. 2008;135:100-10.
-
(2008)
Gastroenterology
, vol.135
, pp. 100-110
-
-
Ratziu, V.1
Giral, P.2
Jacqueminet, S.3
Charlotte, F.4
Hartemann-Heurtier, A.5
Serfaty, L.6
Podevin, P.7
Lacorte, J.M.8
Bernhardt, C.9
Bruckert, E.10
Grimaldi, A.11
Poynard, T.12
-
153
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissenand SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356:2457-71.
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2471
-
-
Nissenand, S.E.1
Wolski, K.2
-
154
-
-
84855572961
-
The role of metformin in the management of NAFLD
-
22194737
-
Mazza A, Fruci B, Garinis GA, Giuliano S, Malaguarnera R, Belfiore A. The role of metformin in the management of NAFLD. Exp Diabetes Res. 2012;2012:716404.
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 716404
-
-
Mazza, A.1
Fruci, B.2
Garinis, G.A.3
Giuliano, S.4
Malaguarnera, R.5
Belfiore, A.6
-
155
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
17135584
-
Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, Balas B, Gastaldelli A, Tio F, Pulcini J, Berria R, Ma JZ, Dwivedi S, Havranek R, Fincke C, DeFronzo R, Bannayan GA, Schenker S, Cusi K. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 2006;355:2297-307.
-
(2006)
N Engl J Med
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
Balas, B.7
Gastaldelli, A.8
Tio, F.9
Pulcini, J.10
Berria, R.11
Ma, J.Z.12
Dwivedi, S.13
Havranek, R.14
Fincke, C.15
Defronzo, R.16
Bannayan, G.A.17
Schenker, S.18
Cusi, K.19
-
156
-
-
84881190165
-
The effect of pioglitazone and metformin on liver function tests, insulin resistance, and liver fat content in nonalcoholic fatty liver disease: A randomized double blinded clinical trial
-
23930133
-
Razavizade M, Jamali R, Arj A, Matini SM, Moraveji A, Taherkhani E. The effect of pioglitazone and metformin on liver function tests, insulin resistance, and liver fat content in nonalcoholic fatty liver disease: a randomized double blinded clinical trial. Hepat Mon. 2013;13:e9270.
-
(2013)
Hepat Mon
, vol.13
, pp. 9270
-
-
Razavizade, M.1
Jamali, R.2
Arj, A.3
Matini, S.M.4
Moraveji, A.5
Taherkhani, E.6
-
157
-
-
77649144555
-
Pioglitazone: Side effect and safety profile
-
Shahand P, Mudaliar S. Pioglitazone: side effect and safety profile. Expert Opin Drug Saf. 2010;9:347-54.
-
(2010)
Expert Opin Drug Saf
, vol.9
, pp. 347-354
-
-
Shahand, P.1
Mudaliar, S.2
-
158
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrelland GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 2006;43:S99-112.
-
(2006)
Hepatology
, vol.43
-
-
Farrelland, G.C.1
Larter, C.Z.2
-
159
-
-
84863985184
-
Nonalcoholic fatty liver disease and lipids
-
Wierzbickiand AS, Oben J. Nonalcoholic fatty liver disease and lipids. Curr Opin Lipidol. 2012;23:345-52.
-
(2012)
Curr Opin Lipidol
, vol.23
, pp. 345-352
-
-
Wierzbickiand, A.S.1
Oben, J.2
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