JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs

BMC Cardiovascular Disorders

Volumn 5, Issue , 2005, Pages

  Aggarwal, Dimple ^a   West, Kristy L ^a   Zern, Tosca L ^a   Shrestha, Sudeep ^a   Vergara Jimenez, Marcela ^b   Fernandez, Maria Luz ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b University of Sinaloa   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CHOLESTEROL ESTER TRANSFER PROTEIN; JTT 130; LIPOPROTEIN; LIVER ENZYME; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTILIPEMIC AGENT; CARRIER PROTEIN; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PYRROLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; FATTY LIVER; GUINEA PIG; HOMEOSTASIS; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; RANDOMIZATION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; LIPID METABOLISM; LIVER; METABOLISM; PARTICLE SIZE;

ANIMALS; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; LIVER; MALE; MODELS, ANIMAL; PARTICLE SIZE; PYRROLES; TRIGLYCERIDES;

EID: 26844580001     PISSN: 14712261     EISSN: 14712261     Source Type: Journal    
DOI: 10.1186/1471-2261-5-30     Document Type: Article

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