Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

Journal of Lipid Research

Volumn 53, Issue 5, 2012, Pages 859-867

  Tep, Samnang ^a   Mihaila, Radu ^a   Freeman, Alexander ^a   Pickering, Victoria ^a   Huyhn, Felicia ^a   Tadin Strapps, Marija ^a   Stracks, Allison ^a   Hubbard, Brian ^a   Caldwell, Jeremy ^a   Flanagan, W Michael ^a   Kuklin, Nelly A ^a   Ason, Brandon ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b AMGEN INC   (United States)

Author keywords

Atherosclerosis; Combination therapies; Dyslipidemia; Low density lipoprotein cholesterol; RNAi

Indexed keywords

CHOLESTEROL; DIACYLGLYCEROL ACYLTRANSFERASE 2; FATTY ACID; KETONE; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; SMALL INTERFERING RNA; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; FATTY LIVER; GENE SILENCING; LIPOGENESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

ANIMALS; APOLIPOPROTEINS B; CARRIER PROTEINS; CHOLESTEROL; DIACYLGLYCEROL O-ACYLTRANSFERASE; FATTY LIVER; GENE SILENCING; LIVER; MALE; MICE; RNA, SMALL INTERFERING; TRIGLYCERIDES;

EID: 84860284295     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M021063     Document Type: Article

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