-
1
-
-
33644532233
-
The early history of the ubiquitin field
-
Varshavsky A, (2006) The early history of the ubiquitin field. Protein Sci 15: 647-654
-
(2006)
Protein Sci
, vol.15
, pp. 647-654
-
-
Varshavsky, A.1
-
2
-
-
0038434056
-
A superfamily of protein tags: Ubiquitin, SUMO and related modifiers
-
DOI 10.1016/S0968-0004(03)00113-0
-
Schwartz DC, Hochstrasser M, (2003) A superfamily of protein tags: ubiquitin, SUMO and related modifiers. Trends Biochem Sci 28: 321-328 (Pubitemid 36776295)
-
(2003)
Trends in Biochemical Sciences
, vol.28
, Issue.6
, pp. 321-328
-
-
Schwartz, D.C.1
Hochstrasser, M.2
-
3
-
-
11244309014
-
Proteolysis: From the lysosome to ubiquitin and the proteasome
-
Ciechanover A, (2005) Proteolysis: from the lysosome to ubiquitin and the proteasome. Nat Rev Mol Cell Biol 6: 79-87
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 79-87
-
-
Ciechanover, A.1
-
5
-
-
84861783400
-
Ubiquitin-binding proteins: Decoders of ubiquitin-mediated cellular functions
-
Husnjak K, Dikic I, (2012) Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annu Rev Biochem 81: 291-322
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 291-322
-
-
Husnjak, K.1
Dikic, I.2
-
6
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S, (2009) Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 10: 550-563
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
7
-
-
84898614605
-
RBR E3 ligases at work
-
Smit J, Sixma T, (2014) RBR E3 ligases at work. EMBO Rep 15: 142-154
-
(2014)
EMBO Rep
, vol.15
, pp. 142-154
-
-
Smit, J.1
Sixma, T.2
-
8
-
-
33746016268
-
Mitochondria: More Than Just a Powerhouse
-
DOI 10.1016/j.cub.2006.06.054, PII S0960982206017817
-
McBride HM, Neuspiel M, Wasiak S, (2006) Mitochondria: more than just a powerhouse. Curr Biol 16: R551-R560 (Pubitemid 44066793)
-
(2006)
Current Biology
, vol.16
, Issue.14
-
-
McBride, H.M.1
Neuspiel, M.2
Wasiak, S.3
-
9
-
-
79151480727
-
Ubiquitin-proteasome system and mitochondria - Reciprocity
-
Livnat-Levanon N, Glickman MH, (2011) Ubiquitin-proteasome system and mitochondria-reciprocity. Biochim Biophys Acta 1809: 80-87
-
(2011)
Biochim Biophys Acta
, vol.1809
, pp. 80-87
-
-
Livnat-Levanon, N.1
Glickman, M.H.2
-
10
-
-
78649413837
-
Mitochondrial fusion and fission in cell life and death
-
Westermann B, (2010) Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol 11: 872-884
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 872-884
-
-
Westermann, B.1
-
11
-
-
84858376953
-
Mitochondria: In sickness and in health
-
Nunnari J, Suomalainen A, (2012) Mitochondria: in sickness and in health. Cell 148: 1145-1159
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
12
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
Youle RJ, van der Bliek AM, (2012) Mitochondrial fission, fusion, and stress. Science 337: 1062-1065
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
Van Der Bliek, A.M.2
-
13
-
-
84871820635
-
Mechanistic perspective of mitochondrial fusion: Tubulation vs fragmentation
-
Escobar-Henriques M, Anton F, (2013) Mechanistic perspective of mitochondrial fusion: tubulation vs. fragmentation. Biochim Biophys Acta 1833: 162-175
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 162-175
-
-
Escobar-Henriques, M.1
Anton, F.2
-
14
-
-
84871802627
-
Recent advances into the understanding of mitochondrial fission
-
Elgass K, Pakay J, Ryan MT, Palmer CS, (2013) Recent advances into the understanding of mitochondrial fission. Biochim Biophys Acta 1833: 150-161
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 150-161
-
-
Elgass, K.1
Pakay, J.2
Ryan, M.T.3
Palmer, C.S.4
-
15
-
-
67349250817
-
It takes two to tango: Regulation of G proteins by dimerization
-
Gasper R, Meyer S, Gotthardt K, Sirajuddin M, Wittinghofer A, (2009) It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol 10: 423-429
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 423-429
-
-
Gasper, R.1
Meyer, S.2
Gotthardt, K.3
Sirajuddin, M.4
Wittinghofer, A.5
-
16
-
-
0742288598
-
The dynamin superfamily: Universal membrane tubulation and fission molecules?
-
DOI 10.1038/nrm1313
-
Praefcke GJ, McMahon HT, (2004) The dynamin superfamily: universal membrane tubulation and fission molecules? Nat Rev Mol Cell Biol 5: 133-147 (Pubitemid 38160256)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.2
, pp. 133-147
-
-
Praefcke, G.J.K.1
McMahon, H.T.2
-
17
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
Friedman JR, Lackner LL, West M, DiBenedetto JR, Nunnari J, Voeltz GK, (2011) ER tubules mark sites of mitochondrial division. Science 334: 358-362
-
(2011)
Science
, vol.334
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
Dibenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
19
-
-
67749122635
-
An ER-mitochondria tethering complex revealed by a synthetic biology screen
-
Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P, (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325: 477-481
-
(2009)
Science
, vol.325
, pp. 477-481
-
-
Kornmann, B.1
Currie, E.2
Collins, S.R.3
Schuldiner, M.4
Nunnari, J.5
Weissman, J.S.6
Walter, P.7
-
20
-
-
82955237293
-
Role for cER and Mmr1p in anchorage of mitochondria at sites of polarized surface growth in budding yeast
-
Swayne TC, Zhou C, Boldogh IR, Charalel JK, McFaline-Figueroa JR, Thoms S, Yang C, Leung G, McInnes J, Erdmann R, Pon LA, (2011) Role for cER and Mmr1p in anchorage of mitochondria at sites of polarized surface growth in budding yeast. Curr Biol 21: 1994-1999
-
(2011)
Curr Biol
, vol.21
, pp. 1994-1999
-
-
Swayne, T.C.1
Zhou, C.2
Boldogh, I.R.3
Charalel, J.K.4
McFaline-Figueroa, J.R.5
Thoms, S.6
Yang, C.7
Leung, G.8
McInnes, J.9
Erdmann, R.10
Pon, L.A.11
-
21
-
-
84873460115
-
Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria
-
Lackner LL, Ping H, Graef M, Murley A, Nunnari J, (2013) Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria. Proc Natl Acad Sci USA 110: E458-E467
-
(2013)
Proc Natl Acad Sci USA
, vol.110
-
-
Lackner, L.L.1
Ping, H.2
Graef, M.3
Murley, A.4
Nunnari, J.5
-
22
-
-
84880657411
-
The yeast cell cortical protein Num1 integrates mitochondrial dynamics into cellular architecture
-
Klecker T, Scholz D, Fortsch J, Westermann B, (2013) The yeast cell cortical protein Num1 integrates mitochondrial dynamics into cellular architecture. J Cell Sci 126: 2924-2930
-
(2013)
J Cell Sci
, vol.126
, pp. 2924-2930
-
-
Klecker, T.1
Scholz, D.2
Fortsch, J.3
Westermann, B.4
-
23
-
-
84879059164
-
ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
-
Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J, (2013) ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife 2: e00422
-
(2013)
Elife
, vol.2
-
-
Murley, A.1
Lackner, L.L.2
Osman, C.3
West, M.4
Voeltz, G.K.5
Walter, P.6
Nunnari, J.7
-
24
-
-
48749116067
-
Ubiquitin-Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion
-
Cohen MM, Leboucher GP, Livnat-Levanon N, Glickman MH, Weissman AM, (2008) Ubiquitin-Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion. Mol Biol Cell 19: 2457-2464
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2457-2464
-
-
Cohen, M.M.1
Leboucher, G.P.2
Livnat-Levanon, N.3
Glickman, M.H.4
Weissman, A.M.5
-
25
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, Whitworth AJ, (2010) Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci USA 107: 5018-5023
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
26
-
-
79952369437
-
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts
-
Rakovic A, Grunewald A, Kottwitz J, Bruggemann N, Pramstaller PP, Lohmann K, Klein C, (2011) Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS ONE 6: e16746
-
(2011)
PLoS ONE
, vol.6
-
-
Rakovic, A.1
Grunewald, A.2
Kottwitz, J.3
Bruggemann, N.4
Pramstaller, P.P.5
Lohmann, K.6
Klein, C.7
-
27
-
-
73949125579
-
A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover
-
Amiott EA, Cohen MM, Saint-Georges Y, Weissman AM, Shaw JM, (2009) A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover. Mol Biol Cell 20: 5026-5035
-
(2009)
Mol Biol Cell
, vol.20
, pp. 5026-5035
-
-
Amiott, E.A.1
Cohen, M.M.2
Saint-Georges, Y.3
Weissman, A.M.4
Shaw, J.M.5
-
28
-
-
21444442598
-
Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae
-
DOI 10.1074/jbc.M500807200
-
Neutzner A, Youle RJ, (2005) Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae. J Biol Chem 280: 18598-18603 (Pubitemid 41379558)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 18598-18603
-
-
Neutzner, A.1
Youle, R.J.2
-
29
-
-
33747389446
-
Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1
-
DOI 10.1083/jcb.200512079
-
Escobar-Henriques M, Westermann B, Langer T, (2006) Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1. J Cell Biol 173: 645-650 (Pubitemid 46165572)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.5
, pp. 645-650
-
-
Escobar-Henriques, M.1
Westermann, B.2
Langer, T.3
-
30
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L, (2010) The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS ONE 5: e10054
-
(2010)
PLoS ONE
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
31
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW, (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19: 4861-4870
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
32
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ, (2010) Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol 191: 1367-1380
-
(2010)
J Cell Biol
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
33
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser L, Sonnay S, Stafa K, Moore DJ, (2011) Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J Neurochem 118: 636-645
-
(2011)
J Neurochem
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
34
-
-
84865395988
-
Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis
-
Leboucher GP, Tsai YC, Yang M, Shaw KC, Zhou M, Veenstra TD, Glickman MH, Weissman AM, (2012) Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis. Mol Cell 47: 547-557
-
(2012)
Mol Cell
, vol.47
, pp. 547-557
-
-
Leboucher, G.P.1
Tsai, Y.C.2
Yang, M.3
Shaw, K.C.4
Zhou, M.5
Veenstra, T.D.6
Glickman, M.H.7
Weissman, A.M.8
-
35
-
-
67749089562
-
A hyperfused mitochondrial state achieved at G1-S regulates cyclin e buildup and entry into S phase
-
Mitra K, Wunder C, Roysam B, Lin G, Lippincott-Schwartz J, (2009) A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc Natl Acad Sci USA 106: 11960-11965
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11960-11965
-
-
Mitra, K.1
Wunder, C.2
Roysam, B.3
Lin, G.4
Lippincott-Schwartz, J.5
-
36
-
-
84871234101
-
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5
-
Park YY, Cho H, (2012) Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5. Cell Div 7: 25
-
(2012)
Cell Div
, vol.7
, pp. 25
-
-
Park, Y.Y.1
Cho, H.2
-
37
-
-
84878118233
-
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
-
Rana A, Rera M, Walker DW, (2013) Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proc Natl Acad Sci USA 110: 8638-8643
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8638-8643
-
-
Rana, A.1
Rera, M.2
Walker, D.W.3
-
38
-
-
79953132685
-
Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
-
Anton F, Fres JM, Schauss A, Pinson B, Praefcke GJ, Langer T, Escobar-Henriques M, (2011) Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci 124: 1126-1135
-
(2011)
J Cell Sci
, vol.124
, pp. 1126-1135
-
-
Anton, F.1
Fres, J.M.2
Schauss, A.3
Pinson, B.4
Praefcke, G.J.5
Langer, T.6
Escobar-Henriques, M.7
-
39
-
-
79955535769
-
Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion
-
Cohen MM, Amiott EA, Day AR, Leboucher GP, Pryce EN, Glickman MH, McCaffery JM, Shaw JM, Weissman AM, (2011) Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion. J Cell Sci 124: 1403-1410
-
(2011)
J Cell Sci
, vol.124
, pp. 1403-1410
-
-
Cohen, M.M.1
Amiott, E.A.2
Day, A.R.3
Leboucher, G.P.4
Pryce, E.N.5
Glickman, M.H.6
McCaffery, J.M.7
Shaw, J.M.8
Weissman, A.M.9
-
40
-
-
84873433599
-
Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways
-
Anton F, Dittmar G, Langer T, Escobar-Henriques M, (2013) Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways. Mol Cell 49: 487-498
-
(2013)
Mol Cell
, vol.49
, pp. 487-498
-
-
Anton, F.1
Dittmar, G.2
Langer, T.3
Escobar-Henriques, M.4
-
41
-
-
84898664828
-
Small natural molecule uncovers the regulatory mechanism for mitochondrial fusion through inhibition of a deubiquitinase
-
In Press
-
Yue W, Chen Z, Liu H, Yan C, Chen M, Feng D, Yan C, Wu H, Du L, Wang Y, Liu J, Huang X, Xia L, Liu L, Wang X, Jin H, Wang J, Song Z, Hao X, Chen Q, (2013) Small natural molecule uncovers the regulatory mechanism for mitochondrial fusion through inhibition of a deubiquitinase. Cell Res. In Press
-
(2013)
Cell Res
-
-
Yue, W.1
Chen, Z.2
Liu, H.3
Yan, C.4
Chen, M.5
Feng, D.6
Yan, C.7
Wu, H.8
Du, L.9
Wang, Y.10
Liu, J.11
Huang, X.12
Xia, L.13
Liu, L.14
Wang, X.15
Jin, H.16
Wang, J.17
Song, Z.18
Hao, X.19
Chen, Q.20
more..
-
42
-
-
84873423978
-
Activation and degradation of mitofusins: Two pathways regulate mitochondrial fusion by reversible ubiquitylation
-
Wiedemann N, Stiller SB, Pfanner N, (2013) Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation. Mol Cell 49: 423-425
-
(2013)
Mol Cell
, vol.49
, pp. 423-425
-
-
Wiedemann, N.1
Stiller, S.B.2
Pfanner, N.3
-
43
-
-
84875436206
-
Organelle dynamics: Deubiquitylating mitofusin
-
Wrighton KH, (2013) Organelle dynamics: deubiquitylating mitofusin. Nat Rev Mol Cell Biol 14: 130-131
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 130-131
-
-
Wrighton, K.H.1
-
44
-
-
84898648986
-
Ubiquitylation of mammalian mitofusins promotes mitochondrial fusion
-
In Press
-
Escobar-Henriques M, (2014) Ubiquitylation of mammalian mitofusins promotes mitochondrial fusion. Cell Res. In Press
-
(2014)
Cell Res
-
-
Escobar-Henriques, M.1
-
45
-
-
0038037754
-
Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast
-
DOI 10.1091/mbc.E02-12-0831
-
Fritz S, Weinbach N, Westermann B, (2003) Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. Mol Biol Cell 14: 2303-2313 (Pubitemid 36724322)
-
(2003)
Molecular Biology of the Cell
, vol.14
, Issue.6
, pp. 2303-2313
-
-
Fritz, S.1
Weinbach, N.2
Westermann, B.3
-
46
-
-
33748327051
-
Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast
-
DOI 10.1091/mbc.E06-01-0053
-
Dürr M, Escobar-Henriques M, Merz S, Geimer S, Langer T, Westermann B, (2006) Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. Mol Biol Cell 17: 3745-3755 (Pubitemid 44330862)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.9
, pp. 3745-3755
-
-
Durr, M.1
Escobar-Henriques, M.2
Merz, S.3
Geimer, S.4
Langer, T.5
Westermann, B.6
-
47
-
-
13444287961
-
Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity
-
DOI 10.1242/jcs.01565
-
Ishihara N, Eura Y, Mihara K, (2004) Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity. J Cell Sci 117: 6535-6546 (Pubitemid 40214575)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.26
, pp. 6535-6546
-
-
Ishihara, N.1
Eura, Y.2
Mihara, K.3
-
48
-
-
48249124967
-
Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane
-
Nakamura N, Hirose S, (2008) Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol Biol Cell 19: 1903-1911
-
(2008)
Mol Biol Cell
, vol.19
, pp. 1903-1911
-
-
Nakamura, N.1
Hirose, S.2
-
49
-
-
84867032955
-
The intracellular redox state is a core determinant of mitochondrial fusion
-
Shutt T, Geoffrion M, Milne R, McBride HM, (2012) The intracellular redox state is a core determinant of mitochondrial fusion. EMBO Rep 13: 909-915
-
(2012)
EMBO Rep
, vol.13
, pp. 909-915
-
-
Shutt, T.1
Geoffrion, M.2
Milne, R.3
McBride, H.M.4
-
50
-
-
84871426886
-
The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli
-
Lokireddy S, Wijesoma IW, Teng S, Bonala S, Gluckman PD, McFarlane C, Sharma M, Kambadur R, (2012) The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli. Cell Metab 16: 613-624
-
(2012)
Cell Metab
, vol.16
, pp. 613-624
-
-
Lokireddy, S.1
Wijesoma, I.W.2
Teng, S.3
Bonala, S.4
Gluckman, P.D.5
McFarlane, C.6
Sharma, M.7
Kambadur, R.8
-
51
-
-
84876524198
-
Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
-
Fu M, St-Pierre P, Shankar J, Wang PT, Joshi B, Nabi IR, (2013) Regulation of mitophagy by the Gp78 E3 ubiquitin ligase. Mol Biol Cell 24: 1153-1162
-
(2013)
Mol Biol Cell
, vol.24
, pp. 1153-1162
-
-
Fu, M.1
St-Pierre, P.2
Shankar, J.3
Wang, P.T.4
Joshi, B.5
Nabi, I.R.6
-
52
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N, (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608 (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
53
-
-
84879251778
-
Structure of parkin reveals mechanisms for ubiquitin ligase activation
-
Trempe JF, Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong K, Kozlov G, Nagar B, Fon EA, Gehring K, (2013) Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science 340: 1451-1455
-
(2013)
Science
, vol.340
, pp. 1451-1455
-
-
Trempe, J.F.1
Sauvé, V.2
Grenier, K.3
Seirafi, M.4
Tang, M.Y.5
Ménade, M.6
Al-Abdul-Wahid, S.7
Krett, J.8
Wong, K.9
Kozlov, G.10
Nagar, B.11
Fon, E.A.12
Gehring, K.13
-
54
-
-
84881477223
-
Structure of the human Parkin ligase domain in an autoinhibited state
-
Wauer T, Komander D, (2013) Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J 32: 2099-2112
-
(2013)
EMBO J
, vol.32
, pp. 2099-2112
-
-
Wauer, T.1
Komander, D.2
-
55
-
-
84879674444
-
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
-
Riley BE, Lougheed JC, Callaway K, Velasquez M, Brecht E, Nguyen L, Shaler T, Walker D, Yang Y, Regnstrom K, Diep L, Zhang Z, Chiou S, Bova M, Artis DR, Yao N, Baker J, Yednock T, Johnston JA, (2013) Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nat Commun 4: 1982
-
(2013)
Nat Commun
, vol.4
, pp. 1982
-
-
Riley, B.E.1
Lougheed, J.C.2
Callaway, K.3
Velasquez, M.4
Brecht, E.5
Nguyen, L.6
Shaler, T.7
Walker, D.8
Yang, Y.9
Regnstrom, K.10
Diep, L.11
Zhang, Z.12
Chiou, S.13
Bova, M.14
Artis, D.R.15
Yao, N.16
Baker, J.17
Yednock, T.18
Johnston, J.A.19
-
56
-
-
79551663809
-
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
-
Xu S, Peng G, Wang Y, Fang S, Karbowski M, (2011) The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover. Mol Biol Cell 22: 291-300
-
(2011)
Mol Biol Cell
, vol.22
, pp. 291-300
-
-
Xu, S.1
Peng, G.2
Wang, Y.3
Fang, S.4
Karbowski, M.5
-
57
-
-
78149429951
-
A stress-responsive system for mitochondrial protein degradation
-
Heo JM, Livnat-Levanon N, Taylor EB, Jones KT, Dephoure N, Ring J, Xie J, Brodsky JL, Madeo F, Gygi SP, Ashrafi K, Glickman MH, Rutter J, (2010) A stress-responsive system for mitochondrial protein degradation. Mol Cell 40: 465-480
-
(2010)
Mol Cell
, vol.40
, pp. 465-480
-
-
Heo, J.M.1
Livnat-Levanon, N.2
Taylor, E.B.3
Jones, K.T.4
Dephoure, N.5
Ring, J.6
Xie, J.7
Brodsky, J.L.8
Madeo, F.9
Gygi, S.P.10
Ashrafi, K.11
Glickman, M.H.12
Rutter, J.13
-
58
-
-
84864382366
-
Cdc48p/p97-mediated regulation of mitochondrial morphology is Vms1p-independent
-
Esaki M, Ogura T, (2012) Cdc48p/p97-mediated regulation of mitochondrial morphology is Vms1p-independent. J Struct Biol 179: 112-120
-
(2012)
J Struct Biol
, vol.179
, pp. 112-120
-
-
Esaki, M.1
Ogura, T.2
-
59
-
-
44949231368
-
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
-
Li W, Bengtson MH, Ulbrich A, Matsuda A, Reddy VA, Orth A, Chanda SK, Batalov S, Joazeiro CA, (2008) Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS ONE 3: e1487
-
(2008)
PLoS ONE
, vol.3
-
-
Li, W.1
Bengtson, M.H.2
Ulbrich, A.3
Matsuda, A.4
Reddy, V.A.5
Orth, A.6
Chanda, S.K.7
Batalov, S.8
Joazeiro, C.A.9
-
60
-
-
67650076601
-
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
-
Braschi E, Zunino R, McBride HM, (2009) MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Rep 10: 748-754
-
(2009)
EMBO Rep
, vol.10
, pp. 748-754
-
-
Braschi, E.1
Zunino, R.2
McBride, H.M.3
-
61
-
-
51049095678
-
GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
-
Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB, (2008) GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Res 18: 900-910
-
(2008)
Cell Res
, vol.18
, pp. 900-910
-
-
Zhang, B.1
Huang, J.2
Li, H.L.3
Liu, T.4
Wang, Y.Y.5
Waterman, P.6
Mao, A.P.7
Xu, L.G.8
Zhai, Z.9
Liu, D.10
Marrack, P.11
Shu, H.B.12
-
62
-
-
76649142385
-
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
-
Park YY, Lee S, Karbowski M, Neutzner A, Youle RJ, Cho H, (2010) Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci 123: 619-626
-
(2010)
J Cell Sci
, vol.123
, pp. 619-626
-
-
Park, Y.Y.1
Lee, S.2
Karbowski, M.3
Neutzner, A.4
Youle, R.J.5
Cho, H.6
-
63
-
-
33747613595
-
A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics
-
DOI 10.1038/sj.emboj.7601249, PII 7601249
-
Yonashiro R, Ishido S, Kyo S, Fukuda T, Goto E, Matsuki Y, Ohmura-Hoshino M, Sada K, Hotta H, Yamamura H, Inatome R, Yanagi S, (2006) A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics. EMBO J 25: 3618-3626 (Pubitemid 44264872)
-
(2006)
EMBO Journal
, vol.25
, Issue.15
, pp. 3618-3626
-
-
Yonashiro, R.1
Ishido, S.2
Kyo, S.3
Fukuda, T.4
Goto, E.5
Matsuki, Y.6
Ohmura-Hoshino, M.7
Sada, K.8
Hotta, H.9
Yamamura, H.10
Inatome, R.11
Yanagi, S.12
-
64
-
-
33749253910
-
MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology
-
DOI 10.1038/sj.embor.7400790, PII 7400790
-
Nakamura N, Kimura Y, Tokuda M, Honda S, Hirose S, (2006) MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology. EMBO Rep 7: 1019-1022 (Pubitemid 44480517)
-
(2006)
EMBO Reports
, vol.7
, Issue.10
, pp. 1019-1022
-
-
Nakamura, N.1
Kimura, Y.2
Tokuda, M.3
Honda, S.4
Hirose, S.5
-
65
-
-
84885381258
-
Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation
-
Mitra K, (2013) Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation. BioEssays 35: 955-964
-
(2013)
BioEssays
, vol.35
, pp. 955-964
-
-
Mitra, K.1
-
66
-
-
84875273810
-
New insights into the function and regulation of mitochondrial fission
-
Otera H, Ishihara N, Mihara K, (2013) New insights into the function and regulation of mitochondrial fission. Biochim Biophys Acta 1833: 1256-1268
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 1256-1268
-
-
Otera, H.1
Ishihara, N.2
Mihara, K.3
-
67
-
-
79954569219
-
Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability
-
Horn SR, Thomenius MJ, Johnson ES, Freel CD, Wu JQ, Coloff JL, Yang CS, Tang W, An J, Ilkayeva OR, Rathmell JC, Newgard CB, Kornbluth S, (2011) Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability. Mol Biol Cell 22: 1207-1216
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1207-1216
-
-
Horn, S.R.1
Thomenius, M.J.2
Johnson, E.S.3
Freel, C.D.4
Wu, J.Q.5
Coloff, J.L.6
Yang, C.S.7
Tang, W.8
An, J.9
Ilkayeva, O.R.10
Rathmell, J.C.11
Newgard, C.B.12
Kornbluth, S.13
-
68
-
-
77951235489
-
Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1
-
Cui M, Tang X, Christian WV, Yoon Y, Tieu K, (2010) Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J Biol Chem 285: 11740-11752
-
(2010)
J Biol Chem
, vol.285
, pp. 11740-11752
-
-
Cui, M.1
Tang, X.2
Christian, W.V.3
Yoon, Y.4
Tieu, K.5
-
69
-
-
79953231682
-
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: Implication of dysregulated mitochondrial dynamics in Parkinson disease
-
Wang H, Song P, Du L, Tian W, Yue W, Liu M, Li D, Wang B, Zhu Y, Cao C, Zhou J, Chen Q, (2011) Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem 286: 11649-11658
-
(2011)
J Biol Chem
, vol.286
, pp. 11649-11658
-
-
Wang, H.1
Song, P.2
Du, L.3
Tian, W.4
Yue, W.5
Liu, M.6
Li, D.7
Wang, B.8
Zhu, Y.9
Cao, C.10
Zhou, J.11
Chen, Q.12
-
70
-
-
69249096578
-
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF, (2009) Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J Biol Chem 284: 22938-22951
-
(2009)
J Biol Chem
, vol.284
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
Fett, M.E.3
Schlehe, J.S.4
Kloos, K.5
Lämmermann, K.6
Brunner, B.7
Kurz-Drexler, A.8
Vogel, F.9
Reichert, A.S.10
Bouman, L.11
Vogt-Weisenhorn, D.12
Wurst, W.13
Tatzelt, J.14
Haass, C.15
Winklhofer, K.F.16
-
71
-
-
34347398050
-
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
-
DOI 10.1083/jcb.200611064
-
Karbowski M, Neutzner A, Youle RJ, (2007) The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J Cell Biol 178: 71-84 (Pubitemid 47026403)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.1
, pp. 71-84
-
-
Karbowski, M.1
Neutzner, A.2
Youle, R.J.3
-
72
-
-
45749117188
-
Mitochondrial fragmentation in neurodegeneration
-
DOI 10.1038/nrn2417, PII NRN2417
-
Knott AB, Perkins G, Schwarzenbacher R, Bossy-Wetzel E, (2008) Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci 9: 505-518 (Pubitemid 351873464)
-
(2008)
Nature Reviews Neuroscience
, vol.9
, Issue.7
, pp. 505-518
-
-
Knott, A.B.1
Perkins, G.2
Schwarzenbacher, R.3
Bossy-Wetzel, E.4
-
74
-
-
84871821848
-
The meaning of mitochondrial movement to a neuron's life
-
Lovas JR, Wang X, (2013) The meaning of mitochondrial movement to a neuron's life. Biochim Biophys Acta 1833: 184-194
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 184-194
-
-
Lovas, J.R.1
Wang, X.2
-
75
-
-
23044432581
-
The GTPase dMiro is required for axonal transport of mitochondria to drosophila synapses
-
DOI 10.1016/j.neuron.2005.06.027, PII S0896627305005337
-
Guo X, Macleod GT, Wellington A, Hu F, Panchumarthi S, Schoenfield M, Marin L, Charlton MP, Atwood HL, Zinsmaier KE, (2005) The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron 47: 379-393 (Pubitemid 41073879)
-
(2005)
Neuron
, vol.47
, Issue.3
, pp. 379-393
-
-
Guo, X.1
Macleod, G.T.2
Wellington, A.3
Hu, F.4
Panchumarthi, S.5
Schoenfield, M.6
Marin, L.7
Charlton, M.P.8
Atwood, H.L.9
Zinsmaier, K.E.10
-
76
-
-
33646117742
-
The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking
-
Fransson S, Ruusala A, Aspenstrom P, (2006) The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking. Biochem Biophys Res Commun 344: 500-510
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 500-510
-
-
Fransson, S.1
Ruusala, A.2
Aspenstrom, P.3
-
77
-
-
33646768127
-
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent
-
DOI 10.1083/jcb.200601067
-
Glater EE, Megeath LJ, Stowers RS, Schwarz TL, (2006) Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol 173: 545-557 (Pubitemid 43765201)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.4
, pp. 545-557
-
-
Glater, E.E.1
Megeath, L.J.2
Stowers, R.S.3
Schwarz, T.L.4
-
78
-
-
64549112144
-
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking
-
Weihofen A, Thomas KJ, Ostaszewski BL, Cookson MR, Selkoe DJ, (2009) Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry 48: 2045-2052
-
(2009)
Biochemistry
, vol.48
, pp. 2045-2052
-
-
Weihofen, A.1
Thomas, K.J.2
Ostaszewski, B.L.3
Cookson, M.R.4
Selkoe, D.J.5
-
79
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL, (2011) PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147: 893-906
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
Lavoie, M.J.9
Schwarz, T.L.10
-
80
-
-
84859237566
-
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
-
Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B, (2012) Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet 8: e1002537
-
(2012)
PLoS Genet
, vol.8
-
-
Liu, S.1
Sawada, T.2
Lee, S.3
Yu, W.4
Silverio, G.5
Alapatt, P.6
Millan, I.7
Shen, A.8
Saxton, W.9
Kanao, T.10
Takahashi, R.11
Hattori, N.12
Imai, Y.13
Lu, B.14
-
81
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
-
Misko A, Jiang S, Wegorzewska I, Milbrandt J, Baloh RH, (2010) Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci 30: 4232-4240
-
(2010)
J Neurosci
, vol.30
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
82
-
-
77955865509
-
Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity
-
Twig G, Liu X, Liesa M, Wikstrom JD, Molina AJ, Las G, Yaniv G, Hajnoczky G, Shirihai OS, (2010) Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity. Am J Physiol Cell Physiol 299: C477-C487
-
(2010)
Am J Physiol Cell Physiol
, vol.299
-
-
Twig, G.1
Liu, X.2
Liesa, M.3
Wikstrom, J.D.4
Molina, A.J.5
Las, G.6
Yaniv, G.7
Hajnoczky, G.8
Shirihai, O.S.9
-
83
-
-
33846224191
-
Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations
-
DOI 10.1523/JNEUROSCI.4798-06.2007
-
Baloh RH, Schmidt RE, Pestronk A, Milbrandt J, (2007) Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. J Neurosci 27: 422-430 (Pubitemid 46106016)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.2
, pp. 422-430
-
-
Baloh, R.H.1
Schmidt, R.E.2
Pestronk, A.3
Milbrandt, J.4
-
84
-
-
0025273937
-
Phospholipid synthesis in a membrane fraction associated with mitochondria
-
Vance JE, (1990) Phospholipid synthesis in a membrane fraction associated with mitochondria. J Biol Chem 265: 7248-7256
-
(1990)
J Biol Chem
, vol.265
, pp. 7248-7256
-
-
Vance, J.E.1
-
85
-
-
84871726622
-
Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)
-
Raturi A, Simmen T, (2013) Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM). Biochim Biophys Acta 1833: 213-224
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 213-224
-
-
Raturi, A.1
Simmen, T.2
-
86
-
-
55849094909
-
A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p
-
Ota K, Kito K, Okada S, Ito T, (2008) A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p. Genes Cells 13: 1075-1085
-
(2008)
Genes Cells
, vol.13
, pp. 1075-1085
-
-
Ota, K.1
Kito, K.2
Okada, S.3
Ito, T.4
-
87
-
-
0036198860
-
Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae
-
DOI 10.1091/mbc.01-12-0588
-
Dimmer KS, Fritz S, Fuchs F, Messerschmitt M, Weinbach N, Neupert W, Westermann B, (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13: 847-853 (Pubitemid 34250350)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.3
, pp. 847-853
-
-
Dimmer, K.S.1
Fritz, S.2
Fuchs, F.3
Messerschmitt, M.4
Weinbach, N.5
Neupert, W.6
Westermann, B.7
-
88
-
-
33748316457
-
The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast
-
DOI 10.1091/mbc.E06-02-0145
-
Kondo-Okamoto N, Ohkuni K, Kitagawa K, McCaffery JM, Shaw JM, Okamoto K, (2006) The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. Mol Biol Cell 17: 3756-3767 (Pubitemid 44330863)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.9
, pp. 3756-3767
-
-
Kondo-Okamoto, N.1
Ohkuni, K.2
Kitagawa, K.3
McCaffery, J.M.4
Shaw, J.M.5
Okamoto, K.6
-
89
-
-
20144385980
-
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
-
DOI 10.1038/sj.emboj.7600559
-
Simmen T, Aslan JE, Blagoveshchenskaya AD, Thomas L, Wan L, Xiang Y, Feliciangeli SF, Hung CH, Crump CM, Thomas G, (2005) PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J 24: 717-729 (Pubitemid 40396102)
-
(2005)
EMBO Journal
, vol.24
, Issue.4
, pp. 717-729
-
-
Simmen, T.1
Aslan, J.E.2
Blagoveshchenskaya, A.D.3
Thomas, L.4
Wan, L.5
Xiang, Y.6
Feliciangeli, S.F.7
Hung, C.-H.8
Crump, C.M.9
Thomas, G.10
-
90
-
-
33845692166
-
2+ channels
-
DOI 10.1083/jcb.200608073
-
Szabadkai G, Bianchi K, Varnai P, De Stefani D, Wieckowski MR, Cavagna D, Nagy AI, Balla T, Rizzuto R, (2006) Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol 175: 901-911 (Pubitemid 44969196)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.6
, pp. 901-911
-
-
Szabadkai, G.1
Bianchi, K.2
Varnai, P.3
De Stefani, D.4
Wieckowski, M.R.5
Cavagna, D.6
Nagy, A.I.7
Balla, T.8
Rizzuto, R.9
-
91
-
-
35549006797
-
2+ Signaling and Cell Survival
-
DOI 10.1016/j.cell.2007.08.036, PII S0092867407010999
-
Hayashi T, Su TP, (2007) Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 131: 596-610 (Pubitemid 350017760)
-
(2007)
Cell
, vol.131
, Issue.3
, pp. 596-610
-
-
Hayashi, T.1
Su, T.-P.2
-
92
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito OM, Scorrano L, (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456: 605-610
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
De Brito, O.M.1
Scorrano, L.2
-
93
-
-
84891685535
-
MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2
-
Sugiura A, Nagashima S, Tokuyama T, Amo T, Matsuki Y, Ishido S, Kudo Y, McBride HM, Fukuda T, Matsushita N, Inatome R, Yanagi S, (2013) MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2. Mol Cell 51: 20-34
-
(2013)
Mol Cell
, vol.51
, pp. 20-34
-
-
Sugiura, A.1
Nagashima, S.2
Tokuyama, T.3
Amo, T.4
Matsuki, Y.5
Ishido, S.6
Kudo, Y.7
McBride, H.M.8
Fukuda, T.9
Matsushita, N.10
Inatome, R.11
Yanagi, S.12
-
94
-
-
84863346611
-
HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction
-
Huang CY, Chiang SF, Lin TY, Chiou SH, Chow KC, (2012) HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction. PLoS ONE 7: e33657
-
(2012)
PLoS ONE
, vol.7
-
-
Huang, C.Y.1
Chiang, S.F.2
Lin, T.Y.3
Chiou, S.H.4
Chow, K.C.5
-
95
-
-
79960716413
-
Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
-
Karbowski M, Youle RJ, (2011) Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation. Curr Opin Cell Biol 23: 476-482
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 476-482
-
-
Karbowski, M.1
Youle, R.J.2
-
96
-
-
84879001260
-
The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins
-
Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A, (2013) The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins. Mol Cell Biol 33: 2136-2148
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2136-2148
-
-
Bragoszewski, P.1
Gornicka, A.2
Sztolsztener, M.E.3
Chacinska, A.4
-
97
-
-
84871821553
-
Proteolytic control of mitochondrial function and morphogenesis
-
Anand R, Langer T, Baker MJ, (2013) Proteolytic control of mitochondrial function and morphogenesis. Biochim Biophys Acta 1833: 195-204
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 195-204
-
-
Anand, R.1
Langer, T.2
Baker, M.J.3
-
98
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ, (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183: 795-803
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
99
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W, (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12: 119-131
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
100
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
Chan NC, Salazar AM, Pham AH, Sweredoski MJ, Kolawa NJ, Graham RL, Hess S, Chan DC, (2011) Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20: 1726-1737
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
Hess, S.7
Chan, D.C.8
-
101
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW, (2013) Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 496: 372-376
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
Harper, J.W.7
-
103
-
-
84862605918
-
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage
-
Kageyama Y, Zhang Z, Roda R, Fukaya M, Wakabayashi J, Wakabayashi N, Kensler TW, Reddy PH, Iijima M, Sesaki H, (2012) Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage. J Cell Biol 197: 535-551
-
(2012)
J Cell Biol
, vol.197
, pp. 535-551
-
-
Kageyama, Y.1
Zhang, Z.2
Roda, R.3
Fukaya, M.4
Wakabayashi, J.5
Wakabayashi, N.6
Kensler, T.W.7
Reddy, P.H.8
Iijima, M.9
Sesaki, H.10
-
104
-
-
84871005673
-
The pathways of mitophagy for quality control and clearance of mitochondria
-
Ashrafi G, Schwarz TL, (2013) The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ 20: 31-42
-
(2013)
Cell Death Differ
, vol.20
, pp. 31-42
-
-
Ashrafi, G.1
Schwarz, T.L.2
-
105
-
-
84876475662
-
Programming cancer cells for high expression levels of Mcl1
-
Ertel F, Nguyen M, Roulston A, Shore GC, (2013) Programming cancer cells for high expression levels of Mcl1. EMBO Rep 14: 328-336
-
(2013)
EMBO Rep
, vol.14
, pp. 328-336
-
-
Ertel, F.1
Nguyen, M.2
Roulston, A.3
Shore, G.C.4
-
106
-
-
77956090193
-
Mitochondrial protein import: From proteomics to functional mechanisms
-
Schmidt O, Pfanner N, Meisinger C, (2010) Mitochondrial protein import: from proteomics to functional mechanisms. Nat Rev Mol Cell Biol 11: 655-667
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 655-667
-
-
Schmidt, O.1
Pfanner, N.2
Meisinger, C.3
-
107
-
-
78651487830
-
Regulation of mitochondrial protein import by cytosolic kinases
-
Schmidt O, Harbauer AB, Rao S, Eyrich B, Zahedi RP, Stojanovski D, Schönfisch B, Guiard B, Sickmann A, Pfanner N, Meisinger C, (2011) Regulation of mitochondrial protein import by cytosolic kinases. Cell 144: 227-239
-
(2011)
Cell
, vol.144
, pp. 227-239
-
-
Schmidt, O.1
Harbauer, A.B.2
Rao, S.3
Eyrich, B.4
Zahedi, R.P.5
Stojanovski, D.6
Schönfisch, B.7
Guiard, B.8
Sickmann, A.9
Pfanner, N.10
Meisinger, C.11
-
108
-
-
0041706156
-
A proteomics approach to understanding protein ubiquitination
-
DOI 10.1038/nbt849
-
Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP, (2003) A proteomics approach to understanding protein ubiquitination. Nat Biotechnol 21: 921-926 (Pubitemid 36936199)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.8
, pp. 921-926
-
-
Peng, J.1
Schwartz, D.2
Elias, J.E.3
Thoreen, C.C.4
Cheng, D.5
Marsischky, G.6
Roelofs, J.7
Finley, D.8
Gygi, S.P.9
-
109
-
-
0242300110
-
A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery
-
DOI 10.1073/pnas.2135500100
-
Hitchcock AL, Auld K, Gygi SP, Silver PA, (2003) A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery. Proc Natl Acad Sci USA 100: 12735-12740 (Pubitemid 37339968)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.22
, pp. 12735-12740
-
-
Hitchcock, A.L.1
Auld, K.2
Gygi, S.P.3
Silver, P.A.4
-
110
-
-
82455179484
-
Systematic and quantitative assessment of the ubiquitin-modified proteome
-
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP, (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell 44: 325-340
-
(2011)
Mol Cell
, vol.44
, pp. 325-340
-
-
Kim, W.1
Bennett, E.J.2
Huttlin, E.L.3
Guo, A.4
Li, J.5
Possemato, A.6
Sowa, M.E.7
Rad, R.8
Rush, J.9
Comb, M.J.10
Harper, J.W.11
Gygi, S.P.12
-
111
-
-
84879613791
-
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation
-
Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villen J, (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10: 676-682
-
(2013)
Nat Methods
, vol.10
, pp. 676-682
-
-
Swaney, D.L.1
Beltrao, P.2
Starita, L.3
Guo, A.4
Rush, J.5
Fields, S.6
Krogan, N.J.7
Villen, J.8
-
112
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ, (2010) Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol 191: 933-942
-
(2010)
J Cell Biol
, vol.191
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
113
-
-
84887453820
-
PINK1 is degraded through the N-end rule pathway
-
Yamano K, Youle RJ, (2013) PINK1 is degraded through the N-end rule pathway. Autophagy 9: 1758-1769
-
(2013)
Autophagy
, vol.9
, pp. 1758-1769
-
-
Yamano, K.1
Youle, R.J.2
-
114
-
-
84873045973
-
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
-
Lazarou M, Narendra DP, Jin SM, Tekle E, Banerjee S, Youle RJ, (2013) PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J Cell Biol 200: 163-172
-
(2013)
J Cell Biol
, vol.200
, pp. 163-172
-
-
Lazarou, M.1
Narendra, D.P.2
Jin, S.M.3
Tekle, E.4
Banerjee, S.5
Youle, R.J.6
-
115
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y, Park J, Kim S, Song S, Kwon SK, Lee SH, Kitada T, Kim JM, Chung J, (2008) PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem Biophys Res Commun 377: 975-980
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
116
-
-
84894599877
-
Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy
-
Fedorowicz MA, de Vries-Schneider RL, Rüb C, Becker D, Huang Y, Zhou C, Alessi Wolken DM, Voos W, Liu Y, Przedborski S, (2014) Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy. EMBO Rep 15: 86-93
-
(2014)
EMBO Rep
, vol.15
, pp. 86-93
-
-
Fedorowicz, M.A.1
De Vries-Schneider, R.L.2
Rüb, C.3
Becker, D.4
Huang, Y.5
Zhou, C.6
Alessi Wolken, D.M.7
Voos, W.8
Liu, Y.9
Przedborski, S.10
-
117
-
-
84894546200
-
The many faces of mitophagy
-
Ivatt RM, Whitworth AJ, (2014) The many faces of mitophagy. EMBO Rep 15: 5-6
-
(2014)
EMBO Rep
, vol.15
, pp. 5-6
-
-
Ivatt, R.M.1
Whitworth, A.J.2
-
118
-
-
84890429468
-
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
-
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ, (2013) High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. Nature 504: 291-295
-
(2013)
Nature
, vol.504
, pp. 291-295
-
-
Hasson, S.A.1
Kane, L.A.2
Yamano, K.3
Huang, C.H.4
Sliter, D.A.5
Buehler, E.6
Wang, C.7
Heman-Ackah, S.M.8
Hessa, T.9
Guha, R.10
Martin, S.E.11
Youle, R.J.12
-
119
-
-
84857032953
-
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
-
Lazarou M, Jin SM, Kane LA, Youle RJ, (2012) Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell 22: 320-333
-
(2012)
Dev Cell
, vol.22
, pp. 320-333
-
-
Lazarou, M.1
Jin, S.M.2
Kane, L.A.3
Youle, R.J.4
-
120
-
-
77952326081
-
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
-
Lee JY, Nagano Y, Taylor JP, Lim KL, Yao TP, (2010) Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. J Cell Biol 189: 671-679
-
(2010)
J Cell Biol
, vol.189
, pp. 671-679
-
-
Lee, J.Y.1
Nagano, Y.2
Taylor, J.P.3
Lim, K.L.4
Yao, T.P.5
-
121
-
-
77956252454
-
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming
-
Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB, Dorn GW II, Yin XM, (2010) Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J Biol Chem 285: 27879-27890
-
(2010)
J Biol Chem
, vol.285
, pp. 27879-27890
-
-
Ding, W.X.1
Ni, H.M.2
Li, M.3
Liao, Y.4
Chen, X.5
Stolz, D.B.6
Dorn, I.I.G.W.7
Yin, X.M.8
-
122
-
-
84870013071
-
Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy
-
Sun Y, Vashisht AA, Tchieu J, Wohlschlegel JA, Dreier L, (2012) Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy. J Biol Chem 287: 40652-40660
-
(2012)
J Biol Chem
, vol.287
, pp. 40652-40660
-
-
Sun, Y.1
Vashisht, A.A.2
Tchieu, J.3
Wohlschlegel, J.A.4
Dreier, L.5
-
123
-
-
84876213313
-
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
-
Vincow ES, Merrihew G, Thomas RE, Shulman NJ, Beyer RP, MacCoss MJ, Pallanck LJ, (2013) The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo. Proc Natl Acad Sci USA 110: 6400-6405
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6400-6405
-
-
Vincow, E.S.1
Merrihew, G.2
Thomas, R.E.3
Shulman, N.J.4
Beyer, R.P.5
Maccoss, M.J.6
Pallanck, L.J.7
-
124
-
-
84888163960
-
Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
-
Abeliovich H, Zarei M, Rigbolt KT, Youle RJ, Dengjel J, (2013) Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy. Nat Commun 4: 2789
-
(2013)
Nat Commun
, vol.4
, pp. 2789
-
-
Abeliovich, H.1
Zarei, M.2
Rigbolt, K.T.3
Youle, R.J.4
Dengjel, J.5
-
125
-
-
84862789618
-
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
-
Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S, Chen Q, (2012) Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol 14: 177-185
-
(2012)
Nat Cell Biol
, vol.14
, pp. 177-185
-
-
Liu, L.1
Feng, D.2
Chen, G.3
Chen, M.4
Zheng, Q.5
Song, P.6
Ma, Q.7
Zhu, C.8
Wang, R.9
Qi, W.10
Huang, L.11
Xue, P.12
Li, B.13
Wang, X.14
Jin, H.15
Wang, J.16
Yang, F.17
Liu, P.18
Zhu, Y.19
Sui, S.20
Chen, Q.21
more..
-
126
-
-
84889100159
-
Loss of iron triggers PINK1/Parkin-independent mitophagy
-
Allen GF, Toth R, James J, Ganley IG, (2013) Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep 14: 1127-1135
-
(2013)
EMBO Rep
, vol.14
, pp. 1127-1135
-
-
Allen, G.F.1
Toth, R.2
James, J.3
Ganley, I.G.4
-
127
-
-
79955623510
-
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
-
Gomes LC, Di Benedetto G, Scorrano L, (2011) During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat Cell Biol 13: 589-598
-
(2011)
Nat Cell Biol
, vol.13
, pp. 589-598
-
-
Gomes, L.C.1
Di Benedetto, G.2
Scorrano, L.3
-
128
-
-
67049089786
-
SLP-2 is required for stress-induced mitochondrial hyperfusion
-
Tondera D, Grandemange S, Jourdain A, Karbowski M, Mattenberger Y, Herzig S, Da Cruz S, Clerc P, Raschke I, Merkwirth C, Ehses S, Krause F, Chan DC, Alexander C, Bauer C, Youle R, Langer T, Martinou JC, (2009) SLP-2 is required for stress-induced mitochondrial hyperfusion. EMBO J 28: 1589-1600
-
(2009)
EMBO J
, vol.28
, pp. 1589-1600
-
-
Tondera, D.1
Grandemange, S.2
Jourdain, A.3
Karbowski, M.4
Mattenberger, Y.5
Herzig, S.6
Da Cruz, S.7
Clerc, P.8
Raschke, I.9
Merkwirth, C.10
Ehses, S.11
Krause, F.12
Chan, D.C.13
Alexander, C.14
Bauer, C.15
Youle, R.16
Langer, T.17
Martinou, J.C.18
-
129
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
DOI 10.1038/sj.emboj.7601963, PII 7601963
-
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS, (2008) Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 27: 433-446 (Pubitemid 351161653)
-
(2008)
EMBO Journal
, vol.27
, Issue.2
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.A.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
130
-
-
70350324917
-
Mitochondrial "kiss-and-run": Interplay between mitochondrial motility and fusion-fission dynamics
-
Liu X, Weaver D, Shirihai O, Hajnoczky G, (2009) Mitochondrial "kiss-and-run": interplay between mitochondrial motility and fusion-fission dynamics. EMBO J 28: 3074-3089
-
(2009)
EMBO J
, vol.28
, pp. 3074-3089
-
-
Liu, X.1
Weaver, D.2
Shirihai, O.3
Hajnoczky, G.4
-
131
-
-
84871464055
-
The missing link: Mul1 signals mitophagy and muscle wasting
-
Attaix D, Taillandier D, (2012) The missing link: mul1 signals mitophagy and muscle wasting. Cell Metab 16: 551-552
-
(2012)
Cell Metab
, vol.16
, pp. 551-552
-
-
Attaix, D.1
Taillandier, D.2
-
132
-
-
84876531457
-
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
-
Chen Y, Dorn GW II, (2013) PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria. Science 340: 471-475
-
(2013)
Science
, vol.340
, pp. 471-475
-
-
Chen, Y.1
Dorn, I.I.G.W.2
-
134
-
-
84859732716
-
Classic and new animal models of Parkinson's disease
-
Blesa J, Phani S, Jackson-Lewis V, Przedborski S, (2012) Classic and new animal models of Parkinson's disease. J Biomed Biotechnol 2012: 845618
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 845618
-
-
Blesa, J.1
Phani, S.2
Jackson-Lewis, V.3
Przedborski, S.4
-
135
-
-
84864150600
-
Mitochondrial dysfunction in Parkinson's disease: Molecular mechanisms and pathophysiological consequences
-
Exner N, Lutz AK, Haass C, Winklhofer KF, (2012) Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J 31: 3038-3062
-
(2012)
EMBO J
, vol.31
, pp. 3038-3062
-
-
Exner, N.1
Lutz, A.K.2
Haass, C.3
Winklhofer, K.F.4
-
136
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
Van Laar VS, Arnold B, Cassady SJ, Chu CT, Burton EA, Berman SB, (2011) Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum Mol Genet 20: 927-940
-
(2011)
Hum Mol Genet
, vol.20
, pp. 927-940
-
-
Van Laar, V.S.1
Arnold, B.2
Cassady, S.J.3
Chu, C.T.4
Burton, E.A.5
Berman, S.B.6
-
137
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
Rakovic A, Shurkewitsch K, Seibler P, Grunewald A, Zanon A, Hagenah J, Krainc D, Klein C, (2013) Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J Biol Chem 288: 2223-2237
-
(2013)
J Biol Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
Krainc, D.7
Klein, C.8
-
139
-
-
58149149970
-
Parkin deficiency increases vulnerability to inflammation-related nigral degeneration
-
Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Treviño I, O'Brien DE, Casey B, Goldberg MS, Tansey MG, (2008) Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci 28: 10825-10834
-
(2008)
J Neurosci
, vol.28
, pp. 10825-10834
-
-
Frank-Cannon, T.C.1
Tran, T.2
Ruhn, K.A.3
Martinez, T.N.4
Hong, J.5
Marvin, M.6
Hartley, M.7
Treviño, I.8
O'Brien, D.E.9
Casey, B.10
Goldberg, M.S.11
Tansey, M.G.12
-
140
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky FH, Lee S, Wibom R, Olson L, Larsson NG, (2011) Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc Natl Acad Sci USA 108: 12937-12942
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
141
-
-
79952303794
-
PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease
-
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troconso JC, Dawson VL, Dawson TM, (2011) PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell 144: 689-702
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
Troconso, J.C.7
Dawson, V.L.8
Dawson, T.M.9
-
142
-
-
84883492814
-
Parkin- and PINK1-dependent mitophagy in neurons: Will the real pathway please stand up?
-
Grenier K, McLelland GL, Fon EA, (2013) Parkin- and PINK1-dependent mitophagy in neurons: will the real pathway please stand up? Front Neurol 4: 100
-
(2013)
Front Neurol
, vol.4
, pp. 100
-
-
Grenier, K.1
McLelland, G.L.2
Fon, E.A.3
-
143
-
-
84868087279
-
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
-
Joselin AP, Hewitt SJ, Callaghan SM, Kim RH, Chung YH, Mak TW, Shen J, Slack RS, Park DS, (2012) ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Hum Mol Genet 21: 4888-4903
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4888-4903
-
-
Joselin, A.P.1
Hewitt, S.J.2
Callaghan, S.M.3
Kim, R.H.4
Chung, Y.H.5
Mak, T.W.6
Shen, J.7
Slack, R.S.8
Park, D.S.9
-
144
-
-
84876886863
-
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
-
Müller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn PH, Lichtenthaler SF, Motori E, Hrelia S, Wurst W, Trümbach D, Langer T, Krappmann D, Dittmar G, Tatzelt J, Winklhofer KF, (2013) The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell 49: 908-921
-
(2013)
Mol Cell
, vol.49
, pp. 908-921
-
-
Müller-Rischart, A.K.1
Pilsl, A.2
Beaudette, P.3
Patra, M.4
Hadian, K.5
Funke, M.6
Peis, R.7
Deinlein, A.8
Schweimer, C.9
Kuhn, P.H.10
Lichtenthaler, S.F.11
Motori, E.12
Hrelia, S.13
Wurst, W.14
Trümbach, D.15
Langer, T.16
Krappmann, D.17
Dittmar, G.18
Tatzelt, J.19
Winklhofer, K.F.20
more..
-
145
-
-
84877834622
-
Maternal inheritance of mitochondrial DNA by diverse mechanisms to eliminate paternal mitochondrial DNA
-
Sato M, Sato K, (2013) Maternal inheritance of mitochondrial DNA by diverse mechanisms to eliminate paternal mitochondrial DNA. Biochim Biophys Acta 1833: 1979-1984
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 1979-1984
-
-
Sato, M.1
Sato, K.2
-
146
-
-
84872395711
-
Mitochondria, maternal inheritance, and asymmetric fitness: Why males die younger
-
Wolff JN, Gemmell NJ, (2013) Mitochondria, maternal inheritance, and asymmetric fitness: why males die younger. BioEssays 35: 93-99
-
(2013)
BioEssays
, vol.35
, pp. 93-99
-
-
Wolff, J.N.1
Gemmell, N.J.2
-
147
-
-
0037406742
-
Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132
-
DOI 10.1095/biolreprod.102.012799
-
Sutovsky P, McCauley TC, Sutovsky M, Day BN, (2003) Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132. Biol Reprod 68: 1793-1800 (Pubitemid 36519787)
-
(2003)
Biology of Reproduction
, vol.68
, Issue.5
, pp. 1793-1800
-
-
Sutovsky, P.1
McCauley, T.C.2
Sutovsky, M.3
Day, B.N.4
-
148
-
-
0033883489
-
Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos
-
Sutovsky P, Moreno RD, Ramalho-Santos J, Dominko T, Simerly C, Schatten G, (2000) Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos. Biol Reprod 63: 582-590 (Pubitemid 30639950)
-
(2000)
Biology of Reproduction
, vol.63
, Issue.2
, pp. 582-590
-
-
Sutovsky, P.1
Moreno, R.D.2
Ramalho-Santos, J.3
Dominko, T.4
Simerly, C.5
Schatten, G.6
-
149
-
-
82255192465
-
Degradation of paternal mitochondria by fertilization-triggered autophagy in C elegans embryos
-
Sato M, Sato K, (2011) Degradation of paternal mitochondria by fertilization-triggered autophagy in C. elegans embryos. Science 334: 1141-1144
-
(2011)
Science
, vol.334
, pp. 1141-1144
-
-
Sato, M.1
Sato, K.2
-
150
-
-
82255183165
-
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission
-
Al Rawi S, Louvet-Vallee S, Djeddi A, Sachse M, Culetto E, Hajjar C, Boyd L, Legouis R, Galy V, (2011) Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission. Science 334: 1144-1147
-
(2011)
Science
, vol.334
, pp. 1144-1147
-
-
Al Rawi, S.1
Louvet-Vallee, S.2
Djeddi, A.3
Sachse, M.4
Culetto, E.5
Hajjar, C.6
Boyd, L.7
Legouis, R.8
Galy, V.9
-
151
-
-
84881410399
-
Unique insights into maternal mitochondrial inheritance in mice
-
Luo SM, Ge ZJ, Wang ZW, Jiang ZZ, Wang ZB, Ouyang YC, Hou Y, Schatten H, Sun QY, (2013) Unique insights into maternal mitochondrial inheritance in mice. Proc Natl Acad Sci USA 110: 13038-13043
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 13038-13043
-
-
Luo, S.M.1
Ge, Z.J.2
Wang, Z.W.3
Jiang, Z.Z.4
Wang, Z.B.5
Ouyang, Y.C.6
Hou, Y.7
Schatten, H.8
Sun, Q.Y.9
-
152
-
-
84871807864
-
Mitochondrial-mediated antiviral immunity
-
Koshiba T, (2013) Mitochondrial-mediated antiviral immunity. Biochim Biophys Acta 1833: 225-232
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 225-232
-
-
Koshiba, T.1
-
153
-
-
84873702210
-
Structural basis of innate immune recognition of viral RNA
-
Berke IC, Li Y, Modis Y, (2013) Structural basis of innate immune recognition of viral RNA. Cell Microbiol 15: 386-394
-
(2013)
Cell Microbiol
, vol.15
, pp. 386-394
-
-
Berke, I.C.1
Li, Y.2
Modis, Y.3
-
154
-
-
59749085907
-
MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease
-
Baril M, Racine ME, Penin F, Lamarre D, (2009) MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease. J Virol 83: 1299-1311
-
(2009)
J Virol
, vol.83
, pp. 1299-1311
-
-
Baril, M.1
Racine, M.E.2
Penin, F.3
Lamarre, D.4
-
155
-
-
80052295420
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
(vol 146, pg 448, 2011).
-
Hou FJ, Sun LJ, Zheng H, Skaug B, Jiang QX, Chen ZJ, (2011) MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response (vol 146, pg 448, 2011). Cell 146: 841-841
-
(2011)
Cell
, vol.146
, pp. 841-841
-
-
Hou, F.J.1
Sun, L.J.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
156
-
-
84874346601
-
A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer
-
Sasaki O, Yoshizumi T, Kuboyama M, Ishihara T, Suzuki E, Kawabata S, Koshiba T, (2013) A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer. Biochim Biophys Acta 1833: 1017-1027
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 1017-1027
-
-
Sasaki, O.1
Yoshizumi, T.2
Kuboyama, M.3
Ishihara, T.4
Suzuki, E.5
Kawabata, S.6
Koshiba, T.7
-
157
-
-
84882705934
-
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
-
Liu S, Chen J, Cai X, Wu J, Chen X, Wu YT, Sun L, Chen ZJ, (2013) MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2: e00785
-
(2013)
Elife
, vol.2
-
-
Liu, S.1
Chen, J.2
Cai, X.3
Wu, J.4
Chen, X.5
Wu, Y.T.6
Sun, L.7
Chen, Z.J.8
-
158
-
-
70449726455
-
PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
-
You F, Sun H, Zhou X, Sun W, Liang S, Zhai Z, Jiang Z, (2009) PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nat Immunol 10: 1300-1308
-
(2009)
Nat Immunol
, vol.10
, pp. 1300-1308
-
-
You, F.1
Sun, H.2
Zhou, X.3
Sun, W.4
Liang, S.5
Zhai, Z.6
Jiang, Z.7
-
159
-
-
77953445772
-
The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation
-
Zhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB, (2010) The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. J Immunol 184: 6249-6255
-
(2010)
J Immunol
, vol.184
, pp. 6249-6255
-
-
Zhong, B.1
Zhang, Y.2
Tan, B.3
Liu, T.T.4
Wang, Y.Y.5
Shu, H.B.6
-
160
-
-
77955496554
-
The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein
-
Wei C, Ni C, Song T, Liu Y, Yang X, Zheng Z, Jia Y, Yuan Y, Guan K, Xu Y, Cheng X, Zhang Y, Yang X, Wang Y, Wen C, Wu Q, Shi W, Zhong H, (2010) The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J Immunol 185: 1158-1168
-
(2010)
J Immunol
, vol.185
, pp. 1158-1168
-
-
Wei, C.1
Ni, C.2
Song, T.3
Liu, Y.4
Yang, X.5
Zheng, Z.6
Jia, Y.7
Yuan, Y.8
Guan, K.9
Xu, Y.10
Cheng, X.11
Zhang, Y.12
Yang, X.13
Wang, Y.14
Wen, C.15
Wu, Q.16
Shi, W.17
Zhong, H.18
-
161
-
-
84876980686
-
UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS
-
Wang P, Yang L, Cheng G, Yang G, Xu Z, You F, Sun Q, Lin R, Fikrig E, Sutton RE, (2013) UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS. Cell Rep 3: 1057-1070
-
(2013)
Cell Rep
, vol.3
, pp. 1057-1070
-
-
Wang, P.1
Yang, L.2
Cheng, G.3
Yang, G.4
Xu, Z.5
You, F.6
Sun, Q.7
Lin, R.8
Fikrig, E.9
Sutton, R.E.10
-
162
-
-
70350468688
-
Mitofusin 2 inhibits mitochondrial antiviral signaling
-
Yasukawa K, Oshiumi H, Takeda M, Ishihara N, Yanagi Y, Seya T, Kawabata S, Koshiba T, (2009) Mitofusin 2 inhibits mitochondrial antiviral signaling. Sci Signal 2: ra47
-
(2009)
Sci Signal
, vol.2
-
-
Yasukawa, K.1
Oshiumi, H.2
Takeda, M.3
Ishihara, N.4
Yanagi, Y.5
Seya, T.6
Kawabata, S.7
Koshiba, T.8
-
163
-
-
82555187810
-
Image-based genome-wide siRNA screen identifies selective autophagy factors
-
Orvedahl A, Sumpter R Jr, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B, (2011) Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 480: 113-117
-
(2011)
Nature
, vol.480
, pp. 113-117
-
-
Orvedahl, A.1
Sumpter, Jr.R.2
Xiao, G.3
Ng, A.4
Zou, Z.5
Tang, Y.6
Narimatsu, M.7
Gilpin, C.8
Sun, Q.9
Roth, M.10
Forst, C.V.11
Wrana, J.L.12
Zhang, Y.E.13
Luby-Phelps, K.14
Xavier, R.J.15
Xie, Y.16
Levine, B.17
-
164
-
-
84885576570
-
The ubiquitin ligase parkin mediates resistance to intracellular pathogens
-
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS, (2013) The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature 501: 512-516
-
(2013)
Nature
, vol.501
, pp. 512-516
-
-
Manzanillo, P.S.1
Ayres, J.S.2
Watson, R.O.3
Collins, A.C.4
Souza, G.5
Rae, C.S.6
Schneider, D.S.7
Nakamura, K.8
Shiloh, M.U.9
Cox, J.S.10
|