Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy

EMBO Reports

Volumn 15, Issue 1, 2014, Pages 86-93

  Fedorowicz, Maja A ^a,b   De Vries Schneider, Rosa L A ^a,b   Ru'b, Cornelia ^c   Becker, Dorothea ^c   Huang, Yong ^d   Zhou, Chun ^e   Wolken, Dana M Alessi ^b   Voos, Wolfgang ^c   Liu, Yuhui ^a,b   Przedborski, Serge ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e NONE   (United States)

Author keywords

Autophagy cell death; Mitochondria; Mitophagy; Parkin; Parkinson's disease; PINK1 Subject Categories Membrane Intracellular Transport

Indexed keywords

BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; LEUPEPTIN; PARKIN; PROTEASOME INHIBITOR; PROTEIN BINDING; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE; VALINOMYCIN;

CYTOSOL; ENZYMOLOGY; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MITOPHAGY; PARKINSON DISEASE; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN TRANSPORT;

CYTOSOL; HEK293 CELLS; HELA CELLS; HUMANS; LEUPEPTINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL MEMBRANES; PARKINSON DISEASE; PROTEASOME INHIBITORS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASES; PROTEIN TRANSPORT; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; VALINOMYCIN;

EID: 84894599877     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1002/embr.201337294     Document Type: Article

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