메뉴 건너뛰기




Volumn 165, Issue 2, 2014, Pages 237-247

Ex Vivo production of platelets from stem cells

Author keywords

Megakaryocyte; Megakaryocytopoiesis; Platelet; Stem cells; Transfusion medicine

Indexed keywords

CD34 ANTIGEN;

EID: 84898059442     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12764     Document Type: Review
Times cited : (53)

References (116)
  • 1
    • 84880293423 scopus 로고    scopus 로고
    • Induced regeneration-the progress and promise of direct reprogramming for heart repair
    • Addis, R.C. & Epstein, J.A. (2013) Induced regeneration-the progress and promise of direct reprogramming for heart repair. Nature Medicine, 19, 829-836.
    • (2013) Nature Medicine , vol.19 , pp. 829-836
    • Addis, R.C.1    Epstein, J.A.2
  • 2
    • 84869236762 scopus 로고    scopus 로고
    • Optimizing megakaryocyte polyploidization by targeting multiple pathways of cytokinesis
    • Avanzi, M.P., Chen, A., He, W. & Mitchell, W.B. (2012) Optimizing megakaryocyte polyploidization by targeting multiple pathways of cytokinesis. Transfusion, 52, 2406-2413.
    • (2012) Transfusion , vol.52 , pp. 2406-2413
    • Avanzi, M.P.1    Chen, A.2    He, W.3    Mitchell, W.B.4
  • 3
    • 84896718487 scopus 로고    scopus 로고
    • Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation through MYC and NFE2 downregulation
    • doi: 10.1111/bjh.12709
    • Avanzi, M.P., Goldberg, F., Davila, J., Langhi, D., Chiattone, C. & Mitchell, W.B. (2014) Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation through MYC and NFE2 downregulation. British Journal of Haematology, doi: 10.1111/bjh.12709
    • (2014) British Journal of Haematology
    • Avanzi, M.P.1    Goldberg, F.2    Davila, J.3    Langhi, D.4    Chiattone, C.5    Mitchell, W.B.6
  • 6
    • 79956011582 scopus 로고    scopus 로고
    • Megakaryocytes derived from patients with the classical form of Bernard-Soulier syndrome show no ability to extend proplatelets in vitro
    • Balduini, A., Malara, A., Balduini, C.L. & Noris, P. (2011) Megakaryocytes derived from patients with the classical form of Bernard-Soulier syndrome show no ability to extend proplatelets in vitro. Platelets, 22, 308-311.
    • (2011) Platelets , vol.22 , pp. 308-311
    • Balduini, A.1    Malara, A.2    Balduini, C.L.3    Noris, P.4
  • 8
    • 36249024229 scopus 로고    scopus 로고
    • Cytokinesis: placing and making the final cut
    • Barr, F.A. & Gruneberg, U. (2007) Cytokinesis: placing and making the final cut. Cell, 131, 847-860.
    • (2007) Cell , vol.131 , pp. 847-860
    • Barr, F.A.1    Gruneberg, U.2
  • 9
    • 36448978808 scopus 로고    scopus 로고
    • Transplantation of autologous mononuclear bone marrow stem cells in patients with peripheral arterial disease (the TAM-PAD study)
    • Bartsch, T., Brehm, M., Zeus, T., Kogler, G., Wernet, P. & Strauer, B.E. (2007) Transplantation of autologous mononuclear bone marrow stem cells in patients with peripheral arterial disease (the TAM-PAD study). Clin Res Cardiol, 96, 891-899.
    • (2007) Clin Res Cardiol , vol.96 , pp. 891-899
    • Bartsch, T.1    Brehm, M.2    Zeus, T.3    Kogler, G.4    Wernet, P.5    Strauer, B.E.6
  • 11
    • 0345688868 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets
    • Bergmeier, W., Burger, P.C., Piffath, C.L., Hoffmeister, K.M., Hartwig, J.H., Nieswandt, B. & Wagner, D.D. (2003) Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. Blood, 102, 4229-4235.
    • (2003) Blood , vol.102 , pp. 4229-4235
    • Bergmeier, W.1    Burger, P.C.2    Piffath, C.L.3    Hoffmeister, K.M.4    Hartwig, J.H.5    Nieswandt, B.6    Wagner, D.D.7
  • 16
    • 29244484283 scopus 로고    scopus 로고
    • Cytokinesis and the spindle midzone
    • Bringmann, H. (2005) Cytokinesis and the spindle midzone. Cell Cycle, 4, 1709-1712.
    • (2005) Cell Cycle , vol.4 , pp. 1709-1712
    • Bringmann, H.1
  • 17
    • 33646364562 scopus 로고    scopus 로고
    • Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes
    • Chanprasert, S., Geddis, A.E., Barroga, C., Fox, N.E. & Kaushansky, K. (2006) Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes. Cellular Signalling, 18, 1212-1218.
    • (2006) Cellular Signalling , vol.18 , pp. 1212-1218
    • Chanprasert, S.1    Geddis, A.E.2    Barroga, C.3    Fox, N.E.4    Kaushansky, K.5
  • 18
    • 38049036483 scopus 로고    scopus 로고
    • Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies
    • Chen, J., Tan, K., Zhou, H., Lo, H.F., Roux, D.T., Liddington, R.C. & Diacovo, T.G. (2008) Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies. Nature Biotechnology, 26, 114-119.
    • (2008) Nature Biotechnology , vol.26 , pp. 114-119
    • Chen, J.1    Tan, K.2    Zhou, H.3    Lo, H.F.4    Roux, D.T.5    Liddington, R.C.6    Diacovo, T.G.7
  • 19
    • 0028928884 scopus 로고
    • Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional
    • Choi, E.S., Nichol, J.L., Hokom, M.M., Hornkohl, A.C. & Hunt, P. (1995) Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional. Blood, 85, 402-413.
    • (1995) Blood , vol.85 , pp. 402-413
    • Choi, E.S.1    Nichol, J.L.2    Hokom, M.M.3    Hornkohl, A.C.4    Hunt, P.5
  • 20
    • 0037450786 scopus 로고    scopus 로고
    • Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
    • Clarke, M.C., Savill, J., Jones, D.B., Noble, B.S. & Brown, S.B. (2003) Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death. Journal of Cell Biology, 160, 577-587.
    • (2003) Journal of Cell Biology , vol.160 , pp. 577-587
    • Clarke, M.C.1    Savill, J.2    Jones, D.B.3    Noble, B.S.4    Brown, S.B.5
  • 21
    • 26244456733 scopus 로고    scopus 로고
    • Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design
    • Cortin, V., Garnier, A., Pineault, N., Lemieux, R., Boyer, L. & Proulx, C. (2005) Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design. Experimental Hematology, 33, 1182-1191.
    • (2005) Experimental Hematology , vol.33 , pp. 1182-1191
    • Cortin, V.1    Garnier, A.2    Pineault, N.3    Lemieux, R.4    Boyer, L.5    Proulx, C.6
  • 22
    • 84872837314 scopus 로고    scopus 로고
    • High doses of romiplostim induce proliferation and reduce proplatelet formation by human megakaryocytes
    • Currao, M., Balduini, C.L. & Balduini, A. (2013) High doses of romiplostim induce proliferation and reduce proplatelet formation by human megakaryocytes. PLoS ONE, 8, e54723.
    • (2013) PLoS ONE , vol.8
    • Currao, M.1    Balduini, C.L.2    Balduini, A.3
  • 24
    • 76349113345 scopus 로고    scopus 로고
    • Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
    • Delaney, C., Heimfeld, S., Brashem-Stein, C., Voorhies, H., Manger, R.L. & Bernstein, I.D. (2010) Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nature Medicine, 16, 232-236.
    • (2010) Nature Medicine , vol.16 , pp. 232-236
    • Delaney, C.1    Heimfeld, S.2    Brashem-Stein, C.3    Voorhies, H.4    Manger, R.L.5    Bernstein, I.D.6
  • 25
    • 33746508365 scopus 로고    scopus 로고
    • Megakaryocyte development and platelet production
    • Deutsch, V.R. & Tomer, A. (2006) Megakaryocyte development and platelet production. British Journal of Haematology, 134, 453-466.
    • (2006) British Journal of Haematology , vol.134 , pp. 453-466
    • Deutsch, V.R.1    Tomer, A.2
  • 26
    • 84878486651 scopus 로고    scopus 로고
    • Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside
    • Deutsch, V.R. & Tomer, A. (2013) Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside. British Journal of Haematology, 161, 778-793.
    • (2013) British Journal of Haematology , vol.161 , pp. 778-793
    • Deutsch, V.R.1    Tomer, A.2
  • 27
    • 70349243751 scopus 로고    scopus 로고
    • Exposure of human megakaryocytes to high shear rates accelerates platelet production
    • Dunois-Larde, C., Capron, C., Fichelson, S., Bauer, T., Cramer-Borde, E. & Baruch, D. (2009) Exposure of human megakaryocytes to high shear rates accelerates platelet production. Blood, 114, 1875-1883.
    • (2009) Blood , vol.114 , pp. 1875-1883
    • Dunois-Larde, C.1    Capron, C.2    Fichelson, S.3    Bauer, T.4    Cramer-Borde, E.5    Baruch, D.6
  • 28
    • 0038819114 scopus 로고    scopus 로고
    • RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation
    • Elagib, K.E., Racke, F.K., Mogass, M., Khetawat, R., Delehanty, L.L. & Goldfarb, A.N. (2003) RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation. Blood, 101, 4333-4341.
    • (2003) Blood , vol.101 , pp. 4333-4341
    • Elagib, K.E.1    Racke, F.K.2    Mogass, M.3    Khetawat, R.4    Delehanty, L.L.5    Goldfarb, A.N.6
  • 33
    • 34347382959 scopus 로고    scopus 로고
    • Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices
    • Gadea, G., de Toledo, M., Anguille, C. & Roux, P. (2007) Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. Journal of Cell Biology, 178, 23-30.
    • (2007) Journal of Cell Biology , vol.178 , pp. 23-30
    • Gadea, G.1    de Toledo, M.2    Anguille, C.3    Roux, P.4
  • 34
    • 33645576158 scopus 로고    scopus 로고
    • Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function
    • Gaur, M., Kamata, T., Wang, S., Moran, B., Shattil, S.J. & Leavitt, A.D. (2006) Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. Jornal of Thrombosis and Haemostasis, 4, 436-442.
    • (2006) Jornal of Thrombosis and Haemostasis , vol.4 , pp. 436-442
    • Gaur, M.1    Kamata, T.2    Wang, S.3    Moran, B.4    Shattil, S.J.5    Leavitt, A.D.6
  • 35
    • 79251478398 scopus 로고    scopus 로고
    • Contribution of platelets to tumour metastasis
    • Gay, L.J. & Felding-Habermann, B. (2011) Contribution of platelets to tumour metastasis. Nature Reviews Cancer, 11, 123-134.
    • (2011) Nature Reviews Cancer , vol.11 , pp. 123-134
    • Gay, L.J.1    Felding-Habermann, B.2
  • 39
    • 84875943915 scopus 로고    scopus 로고
    • This niche is a maze; an amazing niche
    • Hanoun, M. & Frenette, P.S. (2013) This niche is a maze; an amazing niche. Cell Stem Cell, 12, 391-392.
    • (2013) Cell Stem Cell , vol.12 , pp. 391-392
    • Hanoun, M.1    Frenette, P.S.2
  • 40
    • 0031014767 scopus 로고    scopus 로고
    • The expression of p-selectin during collection, processing, and storage of platelet concentrates: relationship to loss of in vivo viability
    • Holme, S., Sweeney, J.D., Sawyer, S. & Elfath, M.D. (1997) The expression of p-selectin during collection, processing, and storage of platelet concentrates: relationship to loss of in vivo viability. Transfusion, 37, 12-17.
    • (1997) Transfusion , vol.37 , pp. 12-17
    • Holme, S.1    Sweeney, J.D.2    Sawyer, S.3    Elfath, M.D.4
  • 41
    • 2342451948 scopus 로고    scopus 로고
    • AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
    • Ichikawa, M., Asai, T., Saito, T., Seo, S., Yamazaki, I., Yamagata, T., Mitani, K., Chiba, S., Ogawa, S., Kurokawa, M. & Hirai, H. (2004) AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. Nature Medicine, 10, 299-304.
    • (2004) Nature Medicine , vol.10 , pp. 299-304
    • Ichikawa, M.1    Asai, T.2    Saito, T.3    Seo, S.4    Yamazaki, I.5    Yamagata, T.6    Mitani, K.7    Chiba, S.8    Ogawa, S.9    Kurokawa, M.10    Hirai, H.11
  • 45
    • 0345059964 scopus 로고    scopus 로고
    • Role of apoptotic processes in platelet biogenesis
    • Kaluzhny, Y. & Ravid, K. (2004) Role of apoptotic processes in platelet biogenesis. Acta Haematologica, 111, 67-77.
    • (2004) Acta Haematologica , vol.111 , pp. 67-77
    • Kaluzhny, Y.1    Ravid, K.2
  • 46
    • 0036721472 scopus 로고    scopus 로고
    • BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation
    • Kaluzhny, Y., Yu, G., Sun, S., Toselli, P.A., Nieswandt, B., Jackson, C.W. & Ravid, K. (2002) BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation. Blood, 100, 1670-1678.
    • (2002) Blood , vol.100 , pp. 1670-1678
    • Kaluzhny, Y.1    Yu, G.2    Sun, S.3    Toselli, P.A.4    Nieswandt, B.5    Jackson, C.W.6    Ravid, K.7
  • 47
    • 56049113521 scopus 로고    scopus 로고
    • Effects of inhibitor of Src kinases, SU6656, on differentiation of megakaryocytic progenitors and activity of alpha1,6-fucosyltransferase
    • Kaminska, J., Klimczak-Jajor, E., Skierski, J. & Bany-Laszewicz, U. (2008) Effects of inhibitor of Src kinases, SU6656, on differentiation of megakaryocytic progenitors and activity of alpha1, 6-fucosyltransferase. Acta Biochimica Polonica, 55, 499-506.
    • (2008) Acta Biochimica Polonica , vol.55 , pp. 499-506
    • Kaminska, J.1    Klimczak-Jajor, E.2    Skierski, J.3    Bany-Laszewicz, U.4
  • 48
    • 0013826490 scopus 로고
    • Circulating megakaryocytes and platelet release in the lung
    • Kaufman, R.M., Airo, R., Pollack, S. & Crosby, W.H. (1965) Circulating megakaryocytes and platelet release in the lung. Blood, 26, 720-731.
    • (1965) Blood , vol.26 , pp. 720-731
    • Kaufman, R.M.1    Airo, R.2    Pollack, S.3    Crosby, W.H.4
  • 49
    • 33646490285 scopus 로고    scopus 로고
    • Lineage-specific hematopoietic growth factors
    • Kaushansky, K. (2006) Lineage-specific hematopoietic growth factors. New England Journal of Medicine, 354, 2034-2045.
    • (2006) New England Journal of Medicine , vol.354 , pp. 2034-2045
    • Kaushansky, K.1
  • 50
    • 60049099167 scopus 로고    scopus 로고
    • Platelet production by megakaryocytes: protoplatelet theory justifies cytoplasmic fragmentation model
    • Kosaki, G. (2008) Platelet production by megakaryocytes: protoplatelet theory justifies cytoplasmic fragmentation model. International Journal of Hematology, 88, 255-267.
    • (2008) International Journal of Hematology , vol.88 , pp. 255-267
    • Kosaki, G.1
  • 52
    • 84879373708 scopus 로고    scopus 로고
    • Challenges and promises for the development of donor-independent platelet transfusions
    • Lambert, M.P., Sullivan, S.K., Fuentes, R., French, D.L. & Poncz, M. (2013) Challenges and promises for the development of donor-independent platelet transfusions. Blood, 121, 3319-3324.
    • (2013) Blood , vol.121 , pp. 3319-3324
    • Lambert, M.P.1    Sullivan, S.K.2    Fuentes, R.3    French, D.L.4    Poncz, M.5
  • 53
    • 2342571558 scopus 로고    scopus 로고
    • Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors
    • Lannutti, B.J. & Drachman, J.G. (2004) Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors. Blood, 103, 3736-3743.
    • (2004) Blood , vol.103 , pp. 3736-3743
    • Lannutti, B.J.1    Drachman, J.G.2
  • 54
    • 18544379794 scopus 로고    scopus 로고
    • Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656
    • Lannutti, B.J., Blake, N., Gandhi, M.J., Reems, J.A. & Drachman, J.G. (2005) Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656. Blood, 105, 3875-3878.
    • (2005) Blood , vol.105 , pp. 3875-3878
    • Lannutti, B.J.1    Blake, N.2    Gandhi, M.J.3    Reems, J.A.4    Drachman, J.G.5
  • 55
    • 33748189345 scopus 로고    scopus 로고
    • Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3
    • Larson, M.K. & Watson, S.P. (2006) Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3. Blood, 108, 1509-1514.
    • (2006) Blood , vol.108 , pp. 1509-1514
    • Larson, M.K.1    Watson, S.P.2
  • 56
    • 80455168289 scopus 로고    scopus 로고
    • Manipulation of oxygenation and flow-induced shear stress can increase the in vitro yield of platelets from cord blood
    • Lasky, L.C. & Sullenbarger, B. (2011) Manipulation of oxygenation and flow-induced shear stress can increase the in vitro yield of platelets from cord blood. Tissue Eng Part C Methods, 17, 1081-1088.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 1081-1088
    • Lasky, L.C.1    Sullenbarger, B.2
  • 57
    • 0032857094 scopus 로고    scopus 로고
    • Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation
    • Lerga, A., Crespo, P., Berciano, M., Delgado, M.D., Canelles, M., Cales, C., Richard, C., Ceballos, E., Gutierrez, P., Ajenjo, N., Gutkind, S. & Leon, J. (1999) Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation. Cell Growth and Differentiation, 10, 639-654.
    • (1999) Cell Growth and Differentiation , vol.10 , pp. 639-654
    • Lerga, A.1    Crespo, P.2    Berciano, M.3    Delgado, M.D.4    Canelles, M.5    Cales, C.6    Richard, C.7    Ceballos, E.8    Gutierrez, P.9    Ajenjo, N.10    Gutkind, S.11    Leon, J.12
  • 58
    • 84879907212 scopus 로고    scopus 로고
    • Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells
    • Lim, W.F., Inoue-Yokoo, T., Tan, K.S., Lai, M.I. & Sugiyama, D. (2013) Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells. Stem Cell Res Ther, 4, 71.
    • (2013) Stem Cell Res Ther , vol.4 , pp. 71
    • Lim, W.F.1    Inoue-Yokoo, T.2    Tan, K.S.3    Lai, M.I.4    Sugiyama, D.5
  • 60
  • 62
    • 84555188409 scopus 로고    scopus 로고
    • Culture of megakaryocytes and platelets from subcutaneous adipose tissue and a preadipocyte cell line
    • Matsubara, Y., Murata, M. & Ikeda, Y. (2012) Culture of megakaryocytes and platelets from subcutaneous adipose tissue and a preadipocyte cell line. Methods in Molecular Biology, 788, 249-258.
    • (2012) Methods in Molecular Biology , vol.788 , pp. 249-258
    • Matsubara, Y.1    Murata, M.2    Ikeda, Y.3
  • 64
    • 0036464649 scopus 로고    scopus 로고
    • Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release
    • Mattia, G., Vulcano, F., Milazzo, L., Barca, A., Macioce, G., Giampaolo, A. & Hassan, H.J. (2002) Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release. Blood, 99, 888-897.
    • (2002) Blood , vol.99 , pp. 888-897
    • Mattia, G.1    Vulcano, F.2    Milazzo, L.3    Barca, A.4    Macioce, G.5    Giampaolo, A.6    Hassan, H.J.7
  • 69
    • 84868608463 scopus 로고    scopus 로고
    • Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf
    • Ono, Y., Wang, Y., Suzuki, H., Okamoto, S., Ikeda, Y., Murata, M., Poncz, M. & Matsubara, Y. (2012) Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf. Blood, 120, 3812-3821.
    • (2012) Blood , vol.120 , pp. 3812-3821
    • Ono, Y.1    Wang, Y.2    Suzuki, H.3    Okamoto, S.4    Ikeda, Y.5    Murata, M.6    Poncz, M.7    Matsubara, Y.8
  • 70
    • 0033796946 scopus 로고    scopus 로고
    • Differences in megakaryocyte expansion potential between CD34(+) stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children
    • van den Oudenrijn, S., von dem Borne, A.E. & de Haas, M. (2000) Differences in megakaryocyte expansion potential between CD34(+) stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children. Experimental Hematology, 28, 1054-1061.
    • (2000) Experimental Hematology , vol.28 , pp. 1054-1061
    • van den Oudenrijn, S.1    von dem Borne, A.E.2    de Haas, M.3
  • 71
    • 77949534952 scopus 로고    scopus 로고
    • Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis
    • Pallotta, I., Lovett, M., Rice, W., Kaplan, D.L. & Balduini, A. (2009) Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis. PLoS ONE, 4, e8359.
    • (2009) PLoS ONE , vol.4
    • Pallotta, I.1    Lovett, M.2    Rice, W.3    Kaplan, D.L.4    Balduini, A.5
  • 72
    • 82355171766 scopus 로고    scopus 로고
    • Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes
    • Pallotta, I., Lovett, M., Kaplan, D.L. & Balduini, A. (2011) Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes. Tissue Eng Part C Methods, 17, 1223-1232.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 1223-1232
    • Pallotta, I.1    Lovett, M.2    Kaplan, D.L.3    Balduini, A.4
  • 74
    • 84866157852 scopus 로고    scopus 로고
    • Embryonic versus mesenchymal stem cells in cartilage repair
    • Perera, J.R., Jaiswal, P.K., Khan, W.S. & Adesida, A. (2012) Embryonic versus mesenchymal stem cells in cartilage repair. J Stem Cells, 7, 105-111.
    • (2012) J Stem Cells , vol.7 , pp. 105-111
    • Perera, J.R.1    Jaiswal, P.K.2    Khan, W.S.3    Adesida, A.4
  • 76
    • 84871903653 scopus 로고    scopus 로고
    • Ex vivo differentiation of cord blood stem cells into megakaryocytes and platelets
    • Pineault, N., Robert, A., Cortin, V. & Boyer, L. (2013) Ex vivo differentiation of cord blood stem cells into megakaryocytes and platelets. Methods in Molecular Biology, 946, 205-224.
    • (2013) Methods in Molecular Biology , vol.946 , pp. 205-224
    • Pineault, N.1    Robert, A.2    Cortin, V.3    Boyer, L.4
  • 78
    • 0019130547 scopus 로고
    • The mechanism of platelet release
    • Radley, J.M. & Scurfield, G. (1980) The mechanism of platelet release. Blood, 56, 996-999.
    • (1980) Blood , vol.56 , pp. 996-999
    • Radley, J.M.1    Scurfield, G.2
  • 81
    • 14344255112 scopus 로고    scopus 로고
    • A mini-review on platelet refractoriness
    • Rebulla, P. (2005) A mini-review on platelet refractoriness. Haematologica, 90, 247-253.
    • (2005) Haematologica , vol.90 , pp. 247-253
    • Rebulla, P.1
  • 82
    • 70749094279 scopus 로고    scopus 로고
    • In vitro megakaryocyte production and platelet biogenesis: state of the art
    • Reems, J.A., Pineault, N. & Sun, S. (2010) In vitro megakaryocyte production and platelet biogenesis: state of the art. Transfusion Medicine Reviews, 24, 33-43.
    • (2010) Transfusion Medicine Reviews , vol.24 , pp. 33-43
    • Reems, J.A.1    Pineault, N.2    Sun, S.3
  • 83
    • 84878659017 scopus 로고    scopus 로고
    • Platelets as cellular effectors of inflammation in vascular diseases
    • Rondina, M.T., Weyrich, A.S. & Zimmerman, G.A. (2013) Platelets as cellular effectors of inflammation in vascular diseases. Circulation Research, 112, 1506-1519.
    • (2013) Circulation Research , vol.112 , pp. 1506-1519
    • Rondina, M.T.1    Weyrich, A.S.2    Zimmerman, G.A.3
  • 86
    • 0030307598 scopus 로고    scopus 로고
    • The role of transcription factor NF-E2 in megakaryocyte maturation and platelet production
    • Shivdasani, R.A. (1996) The role of transcription factor NF-E2 in megakaryocyte maturation and platelet production. Stem Cells, 14, 112-115.
    • (1996) Stem Cells , vol.14 , pp. 112-115
    • Shivdasani, R.A.1
  • 88
    • 34147185235 scopus 로고    scopus 로고
    • Megakaryocyte size and concentration in the bone marrow of thrombocytopenic and nonthrombocytopenic neonates
    • Sola-Visner, M.C., Christensen, R.D., Hutson, A.D. & Rimsza, L.M. (2007) Megakaryocyte size and concentration in the bone marrow of thrombocytopenic and nonthrombocytopenic neonates. Pediatric Research, 61, 479-484.
    • (2007) Pediatric Research , vol.61 , pp. 479-484
    • Sola-Visner, M.C.1    Christensen, R.D.2    Hutson, A.D.3    Rimsza, L.M.4
  • 89
    • 30144433626 scopus 로고    scopus 로고
    • Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1
    • Stachura, D.L., Chou, S.T. & Weiss, M.J. (2006) Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. Blood, 107, 87-97.
    • (2006) Blood , vol.107 , pp. 87-97
    • Stachura, D.L.1    Chou, S.T.2    Weiss, M.J.3
  • 92
    • 0034687212 scopus 로고    scopus 로고
    • Microtubules, membranes and cytokinesis
    • Straight, A.F. & Field, C.M. (2000) Microtubules, membranes and cytokinesis. Current Biology, 10, R760-R770.
    • (2000) Current Biology , vol.10
    • Straight, A.F.1    Field, C.M.2
  • 93
    • 57549100621 scopus 로고    scopus 로고
    • Prolonged continuous in vitro human platelet production using three-dimensional scaffolds
    • Sullenbarger, B., Bahng, J.H., Gruner, R., Kotov, N. & Lasky, L.C. (2009) Prolonged continuous in vitro human platelet production using three-dimensional scaffolds. Experimental Hematology, 37, 101-110.
    • (2009) Experimental Hematology , vol.37 , pp. 101-110
    • Sullenbarger, B.1    Bahng, J.H.2    Gruner, R.3    Kotov, N.4    Lasky, L.C.5
  • 94
    • 33847027593 scopus 로고    scopus 로고
    • Blood collection and transfusion in the United States in 2001
    • Sullivan, M.T., Cotten, R., Read, E.J. & Wallace, E.L. (2007) Blood collection and transfusion in the United States in 2001. Transfusion, 47, 385-394.
    • (2007) Transfusion , vol.47 , pp. 385-394
    • Sullivan, M.T.1    Cotten, R.2    Read, E.J.3    Wallace, E.L.4
  • 95
    • 84879694584 scopus 로고    scopus 로고
    • Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation
    • Suzuki, N., Yamazaki, S., Yamaguchi, T., Okabe, M., Masaki, H., Takaki, S., Otsu, M. & Nakauchi, H. (2013) Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. Molecular Therapy, 21, 1424-1431.
    • (2013) Molecular Therapy , vol.21 , pp. 1424-1431
    • Suzuki, N.1    Yamazaki, S.2    Yamaguchi, T.3    Okabe, M.4    Masaki, H.5    Takaki, S.6    Otsu, M.7    Nakauchi, H.8
  • 96
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K. & Yamanaka, S. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131, 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 97
    • 84867572157 scopus 로고    scopus 로고
    • Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application
    • Takayama, N. & Eto, K. (2012) Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application. Cellular and Molecular Life Sciences, 69, 3419-3428.
    • (2012) Cellular and Molecular Life Sciences , vol.69 , pp. 3419-3428
    • Takayama, N.1    Eto, K.2
  • 98
    • 45949091014 scopus 로고    scopus 로고
    • Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors
    • Takayama, N., Nishikii, H., Usui, J., Tsukui, H., Sawaguchi, A., Hiroyama, T., Eto, K. & Nakauchi, H. (2008) Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood, 111, 5298-5306.
    • (2008) Blood , vol.111 , pp. 5298-5306
    • Takayama, N.1    Nishikii, H.2    Usui, J.3    Tsukui, H.4    Sawaguchi, A.5    Hiroyama, T.6    Eto, K.7    Nakauchi, H.8
  • 101
    • 0029836239 scopus 로고    scopus 로고
    • Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization
    • Thompson, A., Zhang, Y., Kamen, D., Jackson, C.W., Cardiff, R.D. & Ravid, K. (1996) Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization. Journal of Biological Chemistry, 271, 22976-22982.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 22976-22982
    • Thompson, A.1    Zhang, Y.2    Kamen, D.3    Jackson, C.W.4    Cardiff, R.D.5    Ravid, K.6
  • 103
    • 84876166603 scopus 로고    scopus 로고
    • Transcription factors in late megakaryopoiesis and related platelet disorders
    • Tijssen, M.R. & Ghevaert, C. (2013) Transcription factors in late megakaryopoiesis and related platelet disorders. Jornal of Thrombosis and Haemostasis, 11, 593-604.
    • (2013) Jornal of Thrombosis and Haemostasis , vol.11 , pp. 593-604
    • Tijssen, M.R.1    Ghevaert, C.2
  • 106
    • 16644379307 scopus 로고    scopus 로고
    • Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment
    • Ungerer, M., Peluso, M., Gillitzer, A., Massberg, S., Heinzmann, U., Schulz, C., Munch, G. & Gawaz, M. (2004) Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment. Circulation Research, 95, e36-e44.
    • (2004) Circulation Research , vol.95
    • Ungerer, M.1    Peluso, M.2    Gillitzer, A.3    Massberg, S.4    Heinzmann, U.5    Schulz, C.6    Munch, G.7    Gawaz, M.8
  • 107
    • 84882993448 scopus 로고    scopus 로고
    • Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions
    • Wang, Y., Chou, B.K., Dowey, S., He, C., Gerecht, S. & Cheng, L. (2013) Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Res, 11, 1103-1116.
    • (2013) Stem Cell Res , vol.11 , pp. 1103-1116
    • Wang, Y.1    Chou, B.K.2    Dowey, S.3    He, C.4    Gerecht, S.5    Cheng, L.6
  • 108
    • 0028233760 scopus 로고
    • Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells
    • Weiss, M.J., Keller, G. & Orkin, S.H. (1994) Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes and Development, 8, 1184-1197.
    • (1994) Genes and Development , vol.8 , pp. 1184-1197
    • Weiss, M.J.1    Keller, G.2    Orkin, S.H.3
  • 109
    • 0032832532 scopus 로고    scopus 로고
    • Thrombopoietin: its role from early hematopoiesis to platelet production
    • Wendling, F. (1999) Thrombopoietin: its role from early hematopoiesis to platelet production. Haematologica, 84, 158-166.
    • (1999) Haematologica , vol.84 , pp. 158-166
    • Wendling, F.1
  • 111
    • 77953891657 scopus 로고    scopus 로고
    • Apoptotic processes in megakaryocytes and platelets
    • White, M.J. & Kile, B.T. (2010) Apoptotic processes in megakaryocytes and platelets. Seminars in Hematology, 47, 227-234.
    • (2010) Seminars in Hematology , vol.47 , pp. 227-234
    • White, M.J.1    Kile, B.T.2
  • 113
    • 84878054886 scopus 로고    scopus 로고
    • Challenges in the management of the blood supply
    • Williamson, L.M. & Devine, D.V. (2013) Challenges in the management of the blood supply. Lancet, 381, 1866-1875.
    • (2013) Lancet , vol.381 , pp. 1866-1875
    • Williamson, L.M.1    Devine, D.V.2
  • 115
    • 84880947792 scopus 로고    scopus 로고
    • Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors
    • Ye, L., Muench, M.O., Fusaki, N., Beyer, A.I., Wang, J., Qi, Z., Yu, J. & Kan, Y.W. (2013) Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors. Stem Cells Transl Med, 2, 558-566.
    • (2013) Stem Cells Transl Med , vol.2 , pp. 558-566
    • Ye, L.1    Muench, M.O.2    Fusaki, N.3    Beyer, A.I.4    Wang, J.5    Qi, Z.6    Yu, J.7    Kan, Y.W.8
  • 116
    • 0033869985 scopus 로고    scopus 로고
    • Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept
    • Zucker-Franklin, D. & Philipp, C.S. (2000) Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept. American Journal of Pathology, 157, 69-74.
    • (2000) American Journal of Pathology , vol.157 , pp. 69-74
    • Zucker-Franklin, D.1    Philipp, C.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.