Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors

Stem Cells Translational Medicine

Volumn 2, Issue 8, 2013, Pages 558-566

  Ye, Lin ^a   Muench, Marcus O ^a,b,c   Fusaki, Noemi ^d,e,f   Beyer, Ashley I ^c   Wang, Jiaming ^a   Qi, Zhongxia ^a   Yu, Jingwei ^a   Wai Kan, Yuet ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BLOOD SYSTEMS RESEARCH INSTITUTE   (United States)

^d DNAVEC Corporation   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f KEIO UNIVERSITY   (Japan)

Author keywords

Differentiation; Hematopoietic progenitors; Reprogramming

Indexed keywords

ANTIGEN; BONE MORPHOGENETIC PROTEIN 4; BREAST CANCER RESISTANCE PROTEIN; CD34 ANTIGEN; DEXAMETHASONE; DNA METHYLTRANSFERASE 3B; FLT3 LIGAND; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 3; INTERLEUKIN 6; KRUPPEL LIKE FACTOR 4; LEUKOSIALIN; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; REX PROTEIN; SENDAI VIRUS VECTOR; SOMATOMEDIN B; STAGE SPECIFIC EMBRYO ANTIGEN 3; STAGE SPECIFIC EMBRYO ANTIGEN 4; STEM CELL FACTOR; TELOMERASE REVERSE TRANSCRIPTASE; THROMBOPOIETIN; TRA 1 60 ANTIGEN; TRA 1 81 ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE REARRANGEMENT; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KARYOTYPING; MALE; MICROARRAY ANALYSIS; MOUSE; MUTATION; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOMA;

EID: 84880947792     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0006     Document Type: Article

References (40)

1. Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872.
2. Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318: 1917-1920.
3. Carvajal-Vergara X, Sevilla A, D'Souza SL et al. Patient-specific induced pluripotent stemcell-derived models of LEOPARD syndrome. Nature 2010;465:808-812.
4. Hargus G, Cooper O, Deleidi M et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc Natl Acad Sci USA 2010;107: 15921-15926.
5. Yazawa M, Hsueh B, Jia X et al. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 2011;471:230-234.
6. Hanna J, Wernig M, Markoulaki S et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007;318:1920-1923.
7. Lee G, Papapetrou EP, Kim H et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009;461:402-406.
8. Marchetto MC, Carromeu C, Acab A et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 2010;143:527-539.
9. Stadtfeld M, Nagaya M, Utikal J et al. Induced pluripotent stem cells generated without viral integration. Science 2008;322:945-949.
10. Yu J, Hu K, Smuga-Otto K et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009;324: 797-801.
11. Okita K, Nakagawa M, Hyenjong H et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008; 322:949-953.
12. Kaji K, Norrby K, Paca A et al. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009; 458:771-775.
13. Jia F, Wilson KD, Sun N et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 2010;7:197-199.
14. Warren L, Manos PD, Ahfeldt T et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010;7:618-630.
15. Anokye-Danso F, Trivedi CM, Juhr D et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 2011;8:376-388.
16. Kim D, Kim CH, Moon JI et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009;4:472-476.
17. Zhou H, Wu S, Joo JY et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-384.
18. Bar-Nur O, Russ HA, Efrat S et al. Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 2011;9:17-23.
19. Kim K, Doi A, Wen B et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010;467:285-290.
20. Kim K, Zhao R, Doi A et al. Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol 2011;29:1117-1119.
21. Staerk J, Dawlaty MM, Gao Q et al. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell 2010;7:20-24.
22. Loh YH, Agarwal S, Park IH et al. Generation of induced pluripotent stem cells from human blood. Blood 2009;113:5476-5479.
23. Seki T, Yuasa S, Oda M et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 2010;7:11-14.
24. Chou BK, Mali P, Huang X et al. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 2011;21:518-529.
25. Li HO, Zhu YF, Asakawa M et al. A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression. J Virol 2000;74:6564-6569.
26. Fusaki N, Ban H, Nishiyama A et al. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009;85:348-362.
27. Ban H, Nishishita N, Fusaki N et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci USA 2011;108:14234-14239.
28. Ye L, Chang JC, Lin C et al. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc Natl Acad Sci USA 2009;106:9826-9830.
29. Ye Z, Zhan H, Mali P et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 2009;114:5473-5480.
30. Ye L, Chang JC, Lin C et al. Generation of induced pluripotent stem cells using site-specific integration with phage integrase. Proc Natl Acad Sci USA 2010;107:19467-19472.
31. Ng ES, Davis RP, Azzola L et al. Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood 2005;106:1601-1603.
32. Ng ES, Davis R, Stanley EG et al. A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies. Nat Protoc 2008;3:768-776.
33. Loh YH, Hartung O, Li H et al. Reprogramming of T cells from human peripheral blood. Cell Stem Cell 2010;7:15-19.
34. Cashen AF, Lazarus, HM, Devine SM. Mobilizing stem cells from normal donors: Is it possible to improve upon G-CSF? Bone Marrow Transplant 2007;39:577-588.
35. Mayshar Y, Ben-David U, Lavon N et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 2010;7:521-531.
36. Taapken SM, Nisler BS, NewtonMAet al. Karotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells. Nat Biotechnol 2011;29:313-314.
37. Martins-Taylor K, Nisler BS, Taapken SM et al. Recurrent copy number variations in human induced pluripotent stem cells. Nat Biotechnol 2011;29:488-491.
38. Martins-Taylor K, Xu RH. Concise review: Genomic stability of human induced pluripotent stem cells. STEM CELLS 2012;30:22-27.
39. Nagler A, Korenstein-Ilan A, Amiel A et al. Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells. Exp Hematol 2004;32:122-130.
40. Mack AA, Kroboth S, Rajesh D et al. Generation of induced pluripotent stem cells from CD34_cells across blood drawn from multiple donors with non-integrating episomal vectors. PLoS One 2011;6:e27956.