메뉴 건너뛰기




Volumn 21, Issue 3, 2011, Pages 530-545

Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice

Author keywords

functional platelets; human embryonic stem cells; in vivo

Indexed keywords

THROMBIN RECEPTOR;

EID: 79952534150     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.8     Document Type: Article
Times cited : (154)

References (44)
  • 1
    • 70749094279 scopus 로고    scopus 로고
    • In vitro megakaryocyte production and platelet biogenesis: State of the art
    • Reems JA, Pineault N, Sun S. In vitro megakaryocyte production and platelet biogenesis: state of the art. Transfus Med Rev 2010;24:33-43.
    • (2010) Transfus Med. Rev. , vol.24 , pp. 33-43
    • Reems, J.A.1    Pineault, N.2    Sun, S.3
  • 2
    • 0013826490 scopus 로고
    • Circulating megakaryocytes and platelet release in the lung
    • Kaufman RM, Airo R, Pollack S, et al. Circulating megakaryocytes and platelet release in the lung. Blood 1965;26:720-731.
    • (1965) Blood , vol.26 , pp. 720-731
    • Kaufman, R.M.1    Airo, R.2    Pollack, S.3
  • 3
    • 0031868521 scopus 로고    scopus 로고
    • Megakaryocyte differentiation events
    • Long MW. Megakaryocyte differentiation events. Semin Hematol 1998;35:192-199. (Pubitemid 28337228)
    • (1998) Seminars in Hematology , vol.35 , Issue.3 , pp. 192-199
    • Long, M.W.1
  • 4
    • 38949153807 scopus 로고    scopus 로고
    • Historical review: Megakaryopoiesis and thrombopoiesis
    • DOI 10.1182/blood-2007-05-088500
    • Kaushansky K. Historical review: megakaryopoiesis and thrombopoiesis. Blood 2008;111:981-986. (Pubitemid 351213374)
    • (2008) Blood , vol.111 , Issue.3 , pp. 981-986
    • Kaushansky, K.1
  • 5
    • 0036792665 scopus 로고    scopus 로고
    • Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: Role of Ets transcription factors
    • Wang X, Crispino JD, Letting DL, et al. Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. EMBO J 2002;21:5225-5234.
    • (2002) EMBO J. , vol.21 , pp. 5225-5234
    • Wang, X.1    Crispino, J.D.2    Letting, D.L.3
  • 6
    • 0034602148 scopus 로고    scopus 로고
    • GATA-1-and FOG-dependent activation of megakaryocytic α IIB gene expression
    • Gaines P, Geiger JN, Knudsen G, et al. GATA-1-and FOG-dependent activation of megakaryocytic α IIB gene expression. J Biol Chem 2000;275:34114-34121.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34114-34121
    • Gaines, P.1    Geiger, J.N.2    Knudsen, G.3
  • 7
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
    • DOI 10.1093/emboj/16.13.3965
    • Shivdasani RA, Fujiwara Y, McDevitt MA, et al. A lineageselective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J 1997;16:3965-3973. (Pubitemid 27281012)
    • (1997) EMBO Journal , vol.16 , Issue.13 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 8
    • 0034762660 scopus 로고    scopus 로고
    • Of mice and men: Comparison of the ultrastructure of megakaryocytes and platelets
    • DOI 10.1016/S0301-472X(01)00733-0, PII S0301472X01007330
    • Schmitt A, Guichard J, Masse JM, et al. Of mice and men: comparison of the ultrastructure of megakaryocytes and platelets. Exp Hematol 2001;29:1295-1302. (Pubitemid 33033306)
    • (2001) Experimental Hematology , vol.29 , Issue.11 , pp. 1295-1302
    • Schmitt, A.1    Guichard, J.2    Masse, J.-M.3    Debili, N.4    Cramer, E.M.5
  • 9
    • 33746508365 scopus 로고    scopus 로고
    • Megakaryocyte development and platelet production
    • DOI 10.1111/j.1365-2141.2006.06215.x
    • Deutsch VR, Tomer A. Megakaryocyte development and platelet production. Br J Haematol 2006;134:453-466. (Pubitemid 44141711)
    • (2006) British Journal of Haematology , vol.134 , Issue.5 , pp. 453-466
    • Deutsch, V.R.1    Tomer, A.2
  • 10
    • 20344393378 scopus 로고    scopus 로고
    • In vivo platelet production from mature megakaryocytes: Does platelet release occur via proplatelets?
    • DOI 10.1532/IJH97.04177
    • Kosaki G. In vivo platelet production from mature megakaryocytes: does platelet release occur via proplatelets? Int J Hematol 2005;81:208-219. (Pubitemid 41364486)
    • (2005) International Journal of Hematology , vol.81 , Issue.3 , pp. 208-219
    • Kosaki, G.1
  • 12
    • 0035353204 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1α increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells
    • Guerriero R, Mattia G, Testa U, et al. Stromal cell-derived factor 1α increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells. Blood 2001;97:2587-2595.
    • (2001) Blood , vol.97 , pp. 2587-2595
    • Guerriero, R.1    Mattia, G.2    Testa, U.3
  • 14
    • 33645576158 scopus 로고    scopus 로고
    • Megakaryocytes derived from human embryonic stem cells: A genetically tractable system to study megakaryocytopoiesis and integrin function
    • Gaur M, Kamata T, Wang S, et al. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J Thromb Haemost 2006;4:436-442.
    • (2006) J. Thromb. Haemost. , vol.4 , pp. 436-442
    • Gaur, M.1    Kamata, T.2    Wang, S.3
  • 15
    • 45949091014 scopus 로고    scopus 로고
    • Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors
    • Takayama N, Nishikii H, Usui J, et al. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood 2008;111:5298-5306.
    • (2008) Blood , vol.111 , pp. 5298-5306
    • Takayama, N.1    Nishikii, H.2    Usui, J.3
  • 17
    • 55949133244 scopus 로고    scopus 로고
    • Robust generation of hemangioblastic progenitors from human embryonic stem cells
    • Lu SJ, Luo C, Holton K, et al. Robust generation of hemangioblastic progenitors from human embryonic stem cells. Regen Med 2008;3:693-704.
    • (2008) Regen Med. , vol.3 , pp. 693-704
    • Lu, S.J.1    Luo, C.2    Holton, K.3
  • 18
    • 58149386519 scopus 로고    scopus 로고
    • Biologic properties and enucleation of red blood cells from human embryonic stem cells
    • Lu SJ, Feng Q, Park JS, et al. Biologic properties and enucleation of red blood cells from human embryonic stem cells. Blood 2008;112:4475-4484.
    • (2008) Blood , vol.112 , pp. 4475-4484
    • Lu, S.J.1    Feng, Q.2    Park, J.S.3
  • 19
    • 0035823641 scopus 로고    scopus 로고
    • Disparate effects of interleukin 11 and thrombopoietin on megakaryocytopoiesis in vitro
    • DOI 10.1006/cyto.2001.0928
    • Taguchi K, Saitoh M, Arai Y, et al. Disparate effects of interleukin 11 and thrombopoietin on megakaryocytopoiesis in vitro. Cytokine 2001;15:241-249. (Pubitemid 34587637)
    • (2001) Cytokine , vol.15 , Issue.5 , pp. 241-249
    • Taguchi, K.1    Saitoh, M.2    Arai, Y.3    Momose, K.4    Ogawa, Y.5    Yasuda, S.6    Miyata, K.7
  • 20
    • 0031733040 scopus 로고    scopus 로고
    • The effects of Mpl-ligand, interleukin-6 and interleukin-11 on megakaryocyte and platelet alpha-granule proteins
    • Philipp CS, Remmler J, Zucker-Franklin D. The effects of Mpl-ligand, interleukin-6 and interleukin-11 on megakaryocyte and platelet α-granule proteins. Thromb Haemost 1998;80:968-975. (Pubitemid 28556701)
    • (1998) Thrombosis and Haemostasis , vol.80 , Issue.6 , pp. 968-975
    • Philipp, C.S.1    Remmler, J.2    Zucker-Franklin, D.3
  • 21
    • 0344394521 scopus 로고    scopus 로고
    • Production of functional platelets by differentiated embryonic stem (ES) cells in vitro
    • DOI 10.1182/blood-2003-06-1773
    • Fujimoto TT, Kohata S, Suzuki H, et al. Production of functional platelets by differentiated embryonic stem (ES) cells in vitro. Blood 2003;102:4044-4051. (Pubitemid 37486987)
    • (2003) Blood , vol.102 , Issue.12 , pp. 4044-4051
    • Fujimoto, T.-T.1    Kohata, S.2    Suzuki, H.3    Miyazaki, H.4    Fujimura, K.5
  • 22
    • 49249092802 scopus 로고    scopus 로고
    • Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells
    • Nishikii H, Eto K, Tamura N, et al. Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. J Exp Med 2008;205:1917-1927.
    • (2008) J. Exp. Med. , vol.205 , pp. 1917-1927
    • Nishikii, H.1    Eto, K.2    Tamura, N.3
  • 24
    • 79952173255 scopus 로고    scopus 로고
    • Glycoprotein Ibα receptor instability is associated with loss of quality in platelets produced in culture
    • Sep. 15. doi:10.1089/scd.2010.0041
    • Robert A, Boyer L, Pineault N. Glycoprotein Ibα receptor instability is associated with loss of quality in platelets produced in culture. Stem Cells Dev 2010 Sep. 15. doi:10.1089/scd.2010.0041
    • (2010) Stem. Cells Dev.
    • Robert, A.1    Boyer, L.2    Pineault, N.3
  • 26
    • 54049152026 scopus 로고    scopus 로고
    • The GPIIb/IIIa (integrin αIIbβ3) odyssey: A technology-driven saga of a receptor with twists, turns, and even a bend
    • Coller BS, Shattil SJ. The GPIIb/IIIa (integrin αIIbβ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend. Blood 2008;112:3011-3025.
    • (2008) Blood , vol.112 , pp. 3011-3025
    • Coller, B.S.1    Shattil, S.J.2
  • 27
    • 0028146157 scopus 로고
    • A point mutation in the integrin β3 cytoplasmic domain (S752→P) impairs bidirectional signaling through αIIbβ3 (platelet glycoprotein IIb-IIIa)
    • Chen YP, O'Toole TE, Ylanne J, et al. A point mutation in the integrin β3 cytoplasmic domain (S752→P) impairs bidirectional signaling through αIIbβ3 (platelet glycoprotein IIb-IIIa). Blood 1994;84:1857-1865.
    • (1994) Blood , vol.84 , pp. 1857-1865
    • Chen, Y.P.1    O'Toole, T.E.2    Ylanne, J.3
  • 28
    • 0034762541 scopus 로고    scopus 로고
    • a-mediated fibrin cross-linking, and facilitates thrombolysis
    • Jirouskova M, Smyth SS, Kudryk B, et al. A hamster antibody to the mouse fibrinogen γ chain inhibits platelet-fibrinogen interactions and FXIIIa-mediated fbrin cross-linking, and facilitates thrombolysis. Thromb Haemost 2001;86:1047-1056. (Pubitemid 32975832)
    • (2001) Thrombosis and Haemostasis , vol.86 , Issue.4 , pp. 1047-1056
    • Jirouskova, M.1    Smyth, S.S.2    Kudryk, B.3    Coller, B.S.4
  • 29
    • 40549084318 scopus 로고    scopus 로고
    • A critical role for extracellular protein disulfide isomerase during thrombus formation in mice
    • DOI 10.1172/JCI34134
    • Cho J, Furie BC, Coughlin SR, et al. A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. J Clin Invest 2008;118:1123-1131. (Pubitemid 351364619)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.3 , pp. 1123-1131
    • Cho, J.1    Furie, B.C.2    Coughlin, S.R.3    Furie, B.4
  • 30
    • 0034918474 scopus 로고    scopus 로고
    • Anti-GPIIb-IIIa drugs: Current strategies and future directions
    • Coller BS. Anti-GPIIb/IIIa drugs: current strategies and future directions. Thromb Haemost 2001;86:427-443. (Pubitemid 32663972)
    • (2001) Thrombosis and Haemostasis , vol.86 , Issue.1 , pp. 427-443
    • Coller, B.S.1
  • 32
    • 34247176342 scopus 로고    scopus 로고
    • In vivo thrombus formation in murine models
    • DOI 10.1161/01.RES.0000261936.85776.5f, PII 0000301220070413000009
    • Sachs UJ, Nieswandt B. In vivo thrombus formation in murine models. Circ Res 2007;100:979-991. (Pubitemid 46598922)
    • (2007) Circulation Research , vol.100 , Issue.7 , pp. 979-991
    • Sachs, U.J.H.1    Nieswandt, B.2
  • 33
    • 34250788226 scopus 로고    scopus 로고
    • In vivo thrombus formation
    • DOI 10.1111/j.1538-7836.2006.02262.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • Furie B, Furie BC. In vivo thrombus formation. J Thromb Haemost 2007;5 Suppl 1:12-17. (Pubitemid 46958811)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 12-17
    • Furie, B.1    Furie, B.C.2
  • 34
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 35
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 36
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu J, Hu J, Smuga-Otto K, et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009;324:797-801.
    • (2009) Science , vol.324 , pp. 797-801
    • Yu, J.1    Hu, J.2    Smuga-Otto, K.3
  • 37
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009;4:472-476.
    • (2009) Cell. Stem. Cell. , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 38
    • 33645639226 scopus 로고    scopus 로고
    • Enhancement of thrombogenesis by plasma fibronectin cross-linked to fbrin and assembled in platelet thrombi
    • Cho J, Mosher DF. Enhancement of thrombogenesis by plasma fibronectin cross-linked to fbrin and assembled in platelet thrombi. Blood 2006;107:3555-3563.
    • (2006) Blood , vol.107 , pp. 3555-3563
    • Cho, J.1    Mosher, D.F.2
  • 39
    • 47149112769 scopus 로고    scopus 로고
    • Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules
    • Patel-Hett S, Richardson JL, Schulze H, et al. Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood 2008;111:4605-4616.
    • (2008) Blood , vol.111 , pp. 4605-4616
    • Patel-Hett, S.1    Richardson, J.L.2    Schulze, H.3
  • 40
    • 28844492181 scopus 로고    scopus 로고
    • Mechanisms of organelle transport and capture along proplatelets during platelet production
    • DOI 10.1182/blood-2005-06-2206
    • Richardson JL, Shivdasani RA, Boers C, et al. Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood 2005;106:4066-4075. (Pubitemid 41775911)
    • (2005) Blood , vol.106 , Issue.13 , pp. 4066-4075
    • Richardson, J.L.1    Shivdasani, R.A.2    Boers, C.3    Hartwig, J.H.4    Italiano Jr., J.E.5
  • 41
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: Pro- and antiangiogenic proteins are organized into separate platelet α granules and differentially released
    • DOI 10.1182/blood-2007-09-113837
    • Italiano JE Jr, Richardson JL, Patel-Hett S, et al. Angiogenesis is regulated by a novel mechanism: pro-and antiangiogenic proteins are organized into separate platelet α granules and differentially released. Blood 2008;111:1227-1233. (Pubitemid 351213404)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1227-1233
    • Italiano Jr., J.E.1    Richardson, J.L.2    Patel-Hett, S.3    Battinelli, E.4    Zaslavsky, A.5    Short, S.6    Ryeom, S.7    Folkman, J.8    Klement, G.L.9
  • 43
    • 33749317677 scopus 로고    scopus 로고
    • Impact of fibronectin assembly on platelet thrombus formation in response to type I collagen and von Willebrand factor
    • DOI 10.1182/blood-2006-02-002063
    • Cho J, Mosher DF. Impact of fibronectin assembly on platelet thrombus formation in response to type I collagen and von Willebrand factor. Blood 2006;108:2229-2236. (Pubitemid 44497504)
    • (2006) Blood , vol.108 , Issue.7 , pp. 2229-2236
    • Cho, J.1    Mosher, D.F.2
  • 44
    • 0036799775 scopus 로고    scopus 로고
    • Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse
    • Falati S, Gross P, Merrill-Skoloff G, et al. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med 2002;8:1175-1181.
    • (2002) Nat. Med. , vol.8 , pp. 1175-1181
    • Falati, S.1    Gross, P.2    Merrill-Skoloff, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.