Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

Blood

Volumn 120, Issue 18, 2012, Pages 3812-3821

  Ono, Yukako ^a   Wang, Yuhuan ^b   Suzuki, Hidenori ^c   Okamoto, Shinichiro ^a   Ikeda, Yasuo ^d   Murata, Mitsuru ^a   Poncz, Mortimer ^b,e   Matsubara, Yumiko ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c NIPPON MEDICAL SCHOOL   (Japan)

^d WASEDA UNIVERSITY   (Japan)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; NUCLEAR FACTOR; NUCLEAR FACTOR ERYTHROID DERIVED 2 P45 UNIT; NUCLEAR FACTOR MAF G; NUCLEAR MAF K; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD SAMPLING; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL STRUCTURE; FEMALE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLOIDY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING TEST; THROMBOCYTE; THROMBOCYTOPENIA;

EID: 84868608463     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-02-413617     Document Type: Article

References (50)

1. Stroncek DF, Rebulla P. Platelet transfusions. Lancet. 2007;370(9585):427-438. (Pubitemid 47189674)
2. Freireich EJ. Origins of platelet transfusion therapy. Transfus Med Rev. 2011;25(3):252-256.
3. Reems JA, Pineault N, Sun S. In vitro megakaryocyte production and platelet biogenesis: state of the art. Transfus Med Rev. 2010;24(1): 33-43.
4. Bartley TD, Bogenberger J, Hunt P, et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell. 1994;77(7):1117- 1124.
5. Kaushansky K, Lok S, Holly RD, et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature. 1994;369(6481):568-571. (Pubitemid 24192526)
6. Kuter DJ, Beeler DL, Rosenberg RD. The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci U S A. 1994;91(23):11104- 11108.
7. Kato T, Ogami K, Shimada Y, et al. Purification and characterization of thrombopoietin. J Biochem. 1995;118(1):229-236.
8. Chang Y, Bluteau D, Debili N, Vainchenker W. From hematopoietic stem cells to platelets. J Thromb Haemost. 2007;5:318-327. (Pubitemid 46958849)
9. Kaushansky K. Historical review: megakaryocytopoiesis and thrombopoiesis. Blood. 2008;111(3): 981-986.
10. Fuentes R, Wang Y, Hirsch J, et al. Infusion of mature megakaryocytes into mice yields functional platelets. J Clin Invest. 2010;120(11):3917- 3922.
11. Eto K, Murphy R, Kerrigan SW, et al. Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI integrin signaling. Proc Natl Acad Sci U S A. 2002;99(20):12819-12824.
12. Fujimoto TT, Kohata S, Suzuki H, Miyazaki H, Fujimura K. Production of functional platelets by differentiated embryonic stem (ES) cells in vitro. Blood. 2003;102(12):4044-4051. (Pubitemid 37486987)
13. Gaur M, Kamata T, Wang S, Moran B, Shattil SJ, Leavitt AD. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J Thromb Haemost. 2006;4(2):436-442.
14. Takayama N, Nishikii H, Usui J, et al. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood. 2008;111(11):5298-5306.
15. Takayama N, Nishimura S, Nakamura S, et al. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med. 2010; 207(13):2817-2830.
16. Matsubara Y, Saito E, Suzuki H, Watanabe N, Murata M, Ikeda Y. Generation of megakaryocytes and platelets from human subcutaneous adipose tissues. Biochem Biophys Res Commun. 2009;378(4):716-720.
17. Matsubara Y, Suzuki H, Ikeda Y, Murata M. Generation of megakaryocytes and platelets from preadipocyte cell line 3T3-L1, but not the parent cell line 3T3, in vitro. Biochem Biophys Res Commun. 2010;402(4):796-800.
18. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126(4):663-676. (Pubitemid 44233629)
19. Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131(5): 861-872. (Pubitemid 350138099)
20. Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007;318(5858):1917- 1920.
21. Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 2010;463(7284):1035-1041.
22. Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 2010;142(3): 375-386.
23. Szabo E, Rampalli S, Risueño RM, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature. 2010;468(7323):521- 526.
24. Kerrigan SW, Gaur M, Murphy RP, Shattil SJ, Leavitt AD. Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation. Blood. 2004;104(5): 1327-1334. (Pubitemid 39166507)
25. Mignotte V, Wall L, deBoer E, Grosveld F, Romeo PH. Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene. Nucleic Acids Res. 1989;17(1): 37-54. (Pubitemid 19030017)
26. Ney PA, Sorrentino BP, Lowrey CH, Nienhuis AW. Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res. 1990;18(20):6011-6017.
27. Ney PA, Andrews NC, Jane SM, et al. Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol. 1993;13(9):5604-5412.
28. Peters LL, Andrews NC, Eicher EM, Davidson MB, Orkin SH, Lux SE. Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NFE2. Nature. 1993;362(6422):768-770. (Pubitemid 23125984)
29. Chan JY, Han X-L, Kan YW. Isolation of cDNA encoding the human NF-E2 protein. Proc Natl Acad Sci U S A. 1993;90(23):11366-11370. (Pubitemid 23354430)
30. Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH. Erythroid transcription factor NF-E2 is a haematopoieticspecific basic-leucine zipper protein. Nature. 1993;362(6422):722-728. (Pubitemid 23125974)
31. Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature. 1994; 367(6463):568-572. (Pubitemid 24055517)
32. Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, et al. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell. 1995;81(5): 695-704.
33. Suzuki M, Murata M, Matsubara Y, et al. Detection of von Willebrand factor-cleaving protease (ADAMTS-13) in human platelets. Biochem Biophys Res Commun. 2004;313(1):212-216. (Pubitemid 37524045)
34. Freytag SO, Paielli DL, Gilbert JD. Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev. 1994; 8(14): 1654-1663. (Pubitemid 24236244)
35. Matsubara Y, Murata M, Ikeda Y. Culture of megakaryocytes and platelets from subcutaneous adipose tissue and a preadipocyte cell line. Methods Mol Biol. 2012;788:249-258.
36. Suzuki H, Kaneko T, Sakamoto T, et al. Redistribution of alpha-granule membrane glycoprotein IIb/IIIa (integrin alpha IIb beta 3) to the surface membrane of human platelets during the release reaction. J Electron Microsc. 1994;43:282-289.
37. Aslan JE, Itakura A, Gertz JM, McCarty OJT. Platelet shape change and spreading. Methods Mol Biol. 2012;788:91-100.
38. Shivdasani RA, Schulze H. Culture, expansion, and differentiation of murine megakaryocytes. Curr Protoc Immunol. 2005;Chapter 22:Unit 22F.6.
39. Hosokawa K, Ohnishi T, Kondo T, et al. A novel automated microchip flow-chamber system to quantitatively evaluate thrombus formation and antithrombotic agents under blood flow conditions. J Thromb Haemost. 2011;9(10):2029-2037.
40. Hosokawa K, Ohnishi T, Fukasawa M, et al. A microchip flow-chamber system for quantitative assessment of the platelet thrombus formation process. Microvasc Res. 2012;83(2):154-161.
41. Cowherd RM, Lyle RE, McGehee RE Jr. Molecular regulation of adipocyte differentiation. Semin Cell Dev Biol. 1999;10(1):3-10. (Pubitemid 129505533)
42. Lecine P, Italiano JE Jr., Kim SW, Villeval JL, Shivdasani RA. Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NFE2. Blood. 2000;96(4):1366-1373. (Pubitemid 30658465)
43. Chen TW, Hwang SM, Chu IM, Hsu SC, Hsieh TB, Yao CL. Characterization and transplantation of induced megakaryocytes from hematopoietic stem cells for rapid platelet recovery by a two-step serum-free procedure. Exp Hematol. 2009;37(11):1330-1339.
44. Shen Y, Romo GM, Dong JF, et al. Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. Blood. 2000;95(3):903-910. (Pubitemid 30062712)
45. Fock EL, Yan F, Pan S, Chong BH. NF-E2- mediated enhancement of megakaryocytic differentiation and platelet production in vitro and in vivo. Exp Hematol. 2008;36(1):78-92. (Pubitemid 350266967)
46. Weintraub H, Tapscott SJ, Davis RL, et al. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci U S A. 1989;86(14):5434-5438. (Pubitemid 19185563)
47. Boylan B, Berndt MC, Kahn ML, Newman PJ. Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of antihuman platelet agents. Blood. 2006;108(3):908- 914.
48. Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods. 1994;174(1-2):83-93.
49. Schmitt A, Guichard J, Massé JM, Debili N, Cramer EM. Of mice and men: comparison of the ultrastructure of megakaryocytes and platelets. Exp Hematol. 2001;29(11):1295-1302. (Pubitemid 33033306)
50. Jirouskova M, Shet AS, Johnson GJ. A guide to murine platelet structure, function, assays, and genetic alterations. J Thromb Haemost. 2007; 5(4):661-669. (Pubitemid 46563562)