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Volumn 946, Issue , 2013, Pages 205-224

Ex vivo differentiation of cord blood stem cells into megakaryocytes and platelets

Author keywords

Cord blood; Flow cytometry; Hematopoietic stem cells; Megakaryocytes; Platelets; Ploidy analysis

Indexed keywords


EID: 84871903653     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-128-8_13     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 31044442504 scopus 로고    scopus 로고
    • Megakaryocyte biology and related disorders
    • Pang L, Weiss MJ, Poncz M (2005) Megakaryocyte biology and related disorders. J Clin Invest 115:3332-3338
    • (2005) J Clin Invest , vol.115 , pp. 3332-3338
    • Pang, L.1    Weiss, M.J.2    Poncz, M.3
  • 2
    • 0031018993 scopus 로고    scopus 로고
    • The development of human megakaryocytes: III. Development of mature megakaryocytes from highly purified committed progenitors in synthetic culture media and inhibition of thrombopoietin-induced polyploidization by interleukin-3
    • Dolzhanskiy A, Basch RS, Karpatkin S (1997) The development of human megakaryocytes: III. Development of mature megakaryocytes from highly purified committed progenitors in synthetic culture media and inhibition of thrombopoietin-induced polyploidization by interleukin-3. Blood 89:426-434
    • (1997) Blood , vol.89 , pp. 426-434
    • Dolzhanskiy, A.1    Basch, R.S.2    Karpatkin, S.3
  • 3
    • 26244456733 scopus 로고    scopus 로고
    • Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design
    • Cortin V, Garnier A, Pineault N, Lemieux R, Boyer L, Proulx C (2005) Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design. Exp Hematol 33:1182-1191
    • (2005) Exp Hematol , vol.33 , pp. 1182-1191
    • Cortin, V.1    Garnier, A.2    Pineault, N.3    Lemieux, R.4    Boyer, L.5    Proulx, C.6
  • 4
    • 0033796946 scopus 로고    scopus 로고
    • Differences in megakaryocyte expansion potential between CD34(+) stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children
    • van den Oudenrijn S, von dem Borne AE, de Haas M (2000) Differences in megakaryocyte expansion potential between CD34(+) stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children. Exp Hematol 28:1054-1061
    • (2000) Exp Hematol , vol.28 , pp. 1054-1061
    • Van Den Oudenrijn, S.1    Von Dem Borne, A.E.2    De Haas, M.3
  • 6
    • 0038076493 scopus 로고    scopus 로고
    • Preferential ex vivo expansion of mega-karyocytes from human cord blood CD34+-enriched cells in the presence of thrombopoietin and limiting amounts of stem cell factor and Flt-3 ligand
    • Proulx C, Boyer L, Hurnanen DR, Lemieux R (2003) Preferential ex vivo expansion of mega-karyocytes from human cord blood CD34+-enriched cells in the presence of thrombopoietin and limiting amounts of stem cell factor and Flt-3 ligand. J Hematother Stem Cell Res 12:179-188
    • (2003) J Hematother Stem Cell Res , vol.12 , pp. 179-188
    • Proulx, C.1    Boyer, L.2    Hurnanen, D.R.3    Lemieux, R.4
  • 7
    • 0032101536 scopus 로고    scopus 로고
    • Thrombopoietin requires additional megakaryocyte-active cytokines for optimal ex vivo expansion of megakaryocyte precursor cells
    • Williams JL, Pipia GG, Datta NS, Long MW (1998) Thrombopoietin requires additional megakaryocyte-active cytokines for optimal ex vivo expansion of megakaryocyte precursor cells. Blood 91:4118-4126
    • (1998) Blood , vol.91 , pp. 4118-4126
    • Williams, J.L.1    Pipia, G.G.2    Datta, N.S.3    Long, M.W.4
  • 9
    • 24144444671 scopus 로고    scopus 로고
    • Ex vivo expansion of megakaryocyte progenitor cells: Cord blood versus mobilized peripheral blood
    • De Bruyn C, Delforge A, Martiat P, Bron D (2005) Ex vivo expansion of megakaryocyte progenitor cells: cord blood versus mobilized peripheral blood. Stem Cells Dev 14:415-424
    • (2005) Stem Cells Dev , vol.14 , pp. 415-424
    • De Bruyn, C.1    Delforge, A.2    Martiat, P.3    Bron, D.4
  • 10
    • 28844454068 scopus 로고    scopus 로고
    • An effective and simple expansion system for megakaryo-cyte progenitor cells using a combination of heparin with thrombopoietin and interleu-kin-11
    • Feng Y, Zhang L, Xiao ZJ, Li B, Liu B, Fan CG, Yuan XF, Han ZC (2005) An effective and simple expansion system for megakaryo-cyte progenitor cells using a combination of heparin with thrombopoietin and interleu-kin-11. Exp Hematol 33:1537-1543
    • (2005) Exp Hematol , vol.33 , pp. 1537-1543
    • Feng, Y.1    Zhang, L.2    Xiao, Z.J.3    Li, B.4    Liu, B.5    Fan, C.G.6    Yuan, X.F.7    Han, Z.C.8
  • 12
    • 0642339113 scopus 로고    scopus 로고
    • Ex vivo expansion of mega-karyocyte precursors from umbilical cord blood CD34 cells in a closed liquid culture system
    • Shaw PH, Gilligan D, Wang XM, Thall PF, Corey SJ (2003) Ex vivo expansion of mega-karyocyte precursors from umbilical cord blood CD34 cells in a closed liquid culture system. Biol Blood Marrow Transplant 9:151-156
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 151-156
    • Shaw, P.H.1    Gilligan, D.2    Wang, X.M.3    Thall, P.F.4    Corey, S.J.5
  • 14
    • 40649110026 scopus 로고    scopus 로고
    • Increased production of megakaryo-cytes near purity from cord blood CD34+ cells using a short two-phase culture system
    • Boyer L, Robert A, Proulx C, Pineault N (2008) Increased production of megakaryo-cytes near purity from cord blood CD34+ cells using a short two-phase culture system. J Immunol Methods 332:82-91
    • (2008) J Immunol Methods , vol.332 , pp. 82-91
    • Boyer, L.1    Robert, A.2    Proulx, C.3    Pineault, N.4
  • 15
    • 0036118717 scopus 로고    scopus 로고
    • Ex vivo expansion of megakaryocyte progenitor cells from normal bone marrow and peripheral blood and from patients with haematological malignancies
    • Blair A, Baker CL, Pamphilon DH, Judson PA (2002) Ex vivo expansion of megakaryocyte progenitor cells from normal bone marrow and peripheral blood and from patients with haematological malignancies. Br J Haematol 116:912-919
    • (2002) Br J Haematol , vol.116 , pp. 912-919
    • Blair, A.1    Baker, C.L.2    Pamphilon, D.H.3    Judson, P.A.4
  • 16
    • 0029081085 scopus 로고
    • Functional human platelet generation in vitro and regulation of cytoplas-mic process formation
    • Choi ES, Hokom MM, Nichol JL, Hornkohl A, Hunt P (1995) Functional human platelet generation in vitro and regulation of cytoplas-mic process formation. C R Acad Sci III 318:387-393
    • (1995) C R Acad Sci III , vol.318 , pp. 387-393
    • Choi, E.S.1    Hokom, M.M.2    Nichol, J.L.3    Hornkohl, A.4    Hunt, P.5
  • 17
    • 16644379307 scopus 로고    scopus 로고
    • Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment
    • Ungerer M, Peluso M, Gillitzer A, Massberg S, Heinzmann U, Schulz C, Munch G, Gawaz M (2004) Generation of functional culture-derived platelets from CD34+ progenitor cells to study transgenes in the platelet environment. Circ Res 95:e36-e44
    • (2004) Circ Res , vol.95
    • Ungerer, M.1    Peluso, M.2    Gillitzer, A.3    Massberg, S.4    Heinzmann, U.5    Schulz, C.6    Munch, G.7    Gawaz, M.8
  • 19
    • 57549100621 scopus 로고    scopus 로고
    • Prolonged continuous in vitro human platelet production using three-dimensional scaffolds
    • Sullenbarger B, Bahng JH, Gruner R, Kotov N, Lasky LC (2009) Prolonged continuous in vitro human platelet production using three-dimensional scaffolds. Exp Hematol 37:101-110
    • (2009) Exp Hematol , vol.37 , pp. 101-110
    • Sullenbarger, B.1    Bahng, J.H.2    Gruner, R.3    Kotov, N.4    Lasky, L.C.5
  • 20
    • 21544461264 scopus 로고    scopus 로고
    • A novel strategy for generating platelet-like fragments from megakaryocytic cell lines and human progenitor cells
    • Gandhi MJ, Drachman JG, Reems JA, Thorning D, Lannutti BJ (2005) A novel strategy for generating platelet-like fragments from megakaryocytic cell lines and human progenitor cells. Blood Cells Mol Dis 35:70-73
    • (2005) Blood Cells Mol Dis , vol.35 , pp. 70-73
    • Gandhi, M.J.1    Drachman, J.G.2    Reems, J.A.3    Thorning, D.4    Lannutti, B.J.5
  • 21
    • 33644845477 scopus 로고    scopus 로고
    • The expansion of mega-karyocyte progenitors from CD34+-enriched mobilized peripheral blood stem cells is inhibited by Flt3-L
    • Case J, Hicks C, Trickett A, Kwan YL, Manoharan A (2006) The expansion of mega-karyocyte progenitors from CD34+-enriched mobilized peripheral blood stem cells is inhibited by Flt3-L. J Interferon Cytokine Res 26:76-82
    • (2006) J Interferon Cytokine Res , vol.26 , pp. 76-82
    • Case, J.1    Hicks, C.2    Trickett, A.3    Kwan, Y.L.4    Manoharan, A.5
  • 22
    • 0034912524 scopus 로고    scopus 로고
    • Expansion of megakaryocyte precursors and stem cells from umbilical cord blood CD34+ cells in collagen and liquid culture media
    • Shaw PH, Olszewski M, Kletzel M (2001) Expansion of megakaryocyte precursors and stem cells from umbilical cord blood CD34+ cells in collagen and liquid culture media. J Hematother Stem Cell Res 10:391-403
    • (2001) J Hematother Stem Cell Res , vol.10 , pp. 391-403
    • Shaw, P.H.1    Olszewski, M.2    Kletzel, M.3
  • 24
    • 70749094279 scopus 로고    scopus 로고
    • In vitro megakaryocyte production and platelet biogenesis: State of the art
    • Reems JA, Pineault N, Sun S (2010) In vitro megakaryocyte production and platelet biogenesis: state of the art. Transfus Med Rev 24:33-43
    • (2010) Transfus Med Rev , vol.24 , pp. 33-43
    • Reems, J.A.1    Pineault, N.2    Sun, S.3
  • 25
    • 34648833029 scopus 로고    scopus 로고
    • Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
    • Battinelli EM, Hartwig JH, Italiano JE Jr (2007) Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis. Curr Opin Hematol 14:419-426
    • (2007) Curr Opin Hematol , vol.14 , pp. 419-426
    • Battinelli, E.M.1    Hartwig, J.H.2    Italiano, Jr.J.E.3
  • 28
    • 54049128933 scopus 로고    scopus 로고
    • Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling
    • Lordier L, Jalil A, Aurade F, Larbret F, Larghero J, Debili N, Vainchenker W, Chang Y (2008) Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling. Blood 112:3164-3174
    • (2008) Blood , vol.112 , pp. 3164-3174
    • Lordier, L.1    Jalil, A.2    Aurade, F.3    Larbret, F.4    Larghero, J.5    Debili, N.6    Vainchenker, W.7    Chang, Y.8
  • 29
  • 30
    • 0033552631 scopus 로고    scopus 로고
    • Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes
    • Italiano JE Jr, Lecine P, Shivdasani RA, Hartwig JH (1999) Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol 147:1299-1312
    • (1999) J Cell Biol , vol.147 , pp. 1299-1312
    • Italiano, Jr.J.E.1    Lecine, P.2    Shivdasani, R.A.3    Hartwig, J.H.4
  • 31
    • 79952173255 scopus 로고    scopus 로고
    • Glycoprotein Ib a receptor instability is associated with loss of quality in platelets produced in culture
    • Robert A, Boyer L, Pineault N (2011) Glycoprotein Ib a receptor instability is associated with loss of quality in platelets produced in culture. Stem Cells Dev 20:379-390
    • (2011) Stem Cells Dev , vol.20 , pp. 379-390
    • Robert, A.1    Boyer, L.2    Pineault, N.3
  • 32
    • 59749097948 scopus 로고    scopus 로고
    • Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells
    • Cortin V, Pineault N, Garnier A (2009) Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells. Methods Mol Biol 482:109-126
    • (2009) Methods Mol Biol , vol.482 , pp. 109-126
    • Cortin, V.1    Pineault, N.2    Garnier, A.3
  • 33
    • 70349637498 scopus 로고    scopus 로고
    • Collingan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (eds) Wiley, New York
    • Darzynkiewick Z, Huang X (2004) In: Collingan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (eds) Current protocols in immunology. Wiley, New York, pp 5.7.1-5.7.18
    • (2004) Current Protocols in Immunology , pp. 571-5718
    • Darzynkiewick, Z.1    Huang, X.2
  • 34
    • 0034890257 scopus 로고    scopus 로고
    • Cord blood megakaryo-cytes do not complete maturation, as indicated by impaired establishment of endomitosis and low expression of G1/S cyclins upon throm-bopoietin-induced differentiation
    • Bornstein R, Garcia-Vela J, Gilsanz F, Auray C, Cales C (2001) Cord blood megakaryo-cytes do not complete maturation, as indicated by impaired establishment of endomitosis and low expression of G1/S cyclins upon throm-bopoietin-induced differentiation. Br J Haematol 114:458-465
    • (2001) Br J Haematol , vol.114 , pp. 458-465
    • Bornstein, R.1    Garcia-Vela, J.2    Gilsanz, F.3    Auray, C.4    Cales, C.5
  • 35
    • 0036464649 scopus 로고    scopus 로고
    • Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release
    • Mattia G, Vulcano F, Milazzo L, Barca A, Macioce G, Giampaolo A, Hassan HJ (2002) Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release. Blood 99:888-897
    • (2002) Blood , vol.99 , pp. 888-897
    • Mattia, G.1    Vulcano, F.2    Milazzo, L.3    Barca, A.4    MacIoce, G.5    Giampaolo, A.6    Hassan, H.J.7
  • 36
    • 20144381266 scopus 로고    scopus 로고
    • Increased megakaryopoie-sis in cultures of CD34-enriched cord blood cells maintained at 39 degrees C
    • Proulx C, Dupuis N, St-Amour I, Boyer L, Lemieux R (2004) Increased megakaryopoie-sis in cultures of CD34-enriched cord blood cells maintained at 39 degrees C. Biotechnol Bioeng 88:675-680
    • (2004) Biotechnol Bioeng , vol.88 , pp. 675-680
    • Proulx, C.1    Dupuis, N.2    St-Amour, I.3    Boyer, L.4    Lemieux, R.5
  • 37
    • 46749113054 scopus 로고    scopus 로고
    • Characterization of the effects and potential mechanisms leading to increased megakaryo-cytic differentiation under mild hyperthermia
    • Pineault N, Boucher J-F, Cayer M-P, Palmqvist L, Boyer L, Lemieux R, Proulx C (2008) Characterization of the effects and potential mechanisms leading to increased megakaryo-cytic differentiation under mild hyperthermia. Stem Cells Dev 17:483-494
    • (2008) Stem Cells Dev , vol.17 , pp. 483-494
    • Pineault, N.1    Boucher, J.-F.2    Cayer, M.-P.3    Palmqvist, L.4    Boyer, L.5    Lemieux, R.6    Proulx, C.7
  • 38
    • 0345688868 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets
    • Bergmeier W, Burger PC, Piffath CL, Hoffmeister KM, Hartwig JH, Nieswandt B, Wagner DD (2003) Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. Blood 102:4229-4235
    • (2003) Blood , vol.102 , pp. 4229-4235
    • Bergmeier, W.1    Burger, P.C.2    Piffath, C.L.3    Hoffmeister, K.M.4    Hartwig, J.H.5    Nieswandt, B.6    Wagner, D.D.7
  • 39
    • 34250006259 scopus 로고    scopus 로고
    • Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization
    • Muntean AG, Pang L, Poncz M, Dowdy SF, Blobel GA, Crispino JD (2007) Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood 109:5199-5207
    • (2007) Blood , vol.109 , pp. 5199-5207
    • Muntean, A.G.1    Pang, L.2    Poncz, M.3    Dowdy, S.F.4    Blobel, G.A.5    Crispino, J.D.6


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