Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application

Cellular and Molecular Life Sciences

Volumn 69, Issue 20, 2012, Pages 3419-3428

  Takayama, Naoya ^a   Eto, Koji ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Disease specific iPSCs; ES iPS sac; Human ESCs; Human iPSCs; MK; Platelet; Transfusion

Indexed keywords

ABL INTERACTOR 1 PROTEIN; ALPHAIIB BETA3 INTEGRIN; ANTIGEN; BETA3 INTEGRIN; CD34 ANTIGEN; CD41A ANTIGEN; CD42 ANTIGEN; GLYCOPROTEIN IB ALPHA; ILOMASTAT; INTEGRIN; MESSENGER RNA; MYC PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1; VON WILLEBRAND FACTOR; WAVE PROTEIN; WAVE2 PROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN;

BLOOD CLOTTING; CELL DIFFERENTIATION; CELL GRANULE; CELL MATURATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SUBPOPULATION; COCULTURE; CONFOCAL LASER MICROSCOPY; CONGENITAL AMEGAKARYOCYTIC THROMBOCYTOPENIA; CULTURE MEDIUM; CULTURE TECHNIQUE; DEVELOPMENTAL BIOLOGY; EMBRYONIC STEM CELL; FEEDER CELL; HEMANGIOBLAST; HLA MATCHING; HUMAN; IN VITRO STUDY; MEGAKARYOCYTE; MEGAKARYOPOIESIS; NONHUMAN; PATHOGENESIS; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REVIEW; THROMBOCYTE; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

BLOOD PLATELETS; CELL DIFFERENTIATION; DEVELOPMENTAL BIOLOGY; HUMANS; MEGAKARYOCYTES; PLURIPOTENT STEM CELLS;

EID: 84867572157     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-0995-4     Document Type: Review

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