Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis

Journal of Neurochemistry

Volumn 129, Issue 2, 2014, Pages 350-361

  Hebron, Michaeline ^a   Chen, Wenqiang ^a,b   Miessau, Matthew J ^c   Lonskaya, Irina ^a   Moussa, Charbel E H ^a,d  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c GEORGETOWN UNIVERSITY   (United States)

^d GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ALS; amino acids; Parkin; TDP 43

Indexed keywords

4 AMINOBUTYRIC ACID; ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; INITIATION FACTOR 4E BINDING PROTEIN; ISOLEUCINE; LACTIC ACID; LENTIVIRUS VECTOR; LEUCINE; PARKIN; TAR DNA BINDING PROTEIN;

AMINO ACID HOMEOSTASIS; AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DEATH; CITRIC ACID CYCLE; CONTROLLED STUDY; HOMEOSTASIS; MALE; METABOLISM; MOTOR CORTEX; MOUSE; NEUROTRANSMITTER METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; TRANSLATION REGULATION;

13C NMR; ALS; AMINO ACIDS; PARKIN; TDP-43;

AMINO ACIDS; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 3; CELL DEATH; CITRIC ACID CYCLE; FLUOROMETRY; GAMMA-AMINOBUTYRIC ACID; GENETIC VECTORS; HOMEOSTASIS; LENTIVIRUS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOTOR CORTEX; NEUROTRANSMITTER AGENTS; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TDP-43 PROTEINOPATHIES; TOR SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84897994248     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12630     Document Type: Article

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