-
1
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
Amador-Ortiz, C., Lin, W.L., Ahmed, Z., Personett, D., Davies, P., Duara, R., Graff-Radford, N.R., Hutton, M.L., Dickson, D.W., 2007. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann. Neurol. 61, 435-445.
-
(2007)
Ann. Neurol.
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
2
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai, T., Hasegawa, M., Akiyama, H., Ikeda, K., Nonaka, T., Mori, H., Mann, D., Tsuchiya, K., Yoshida, M., Hashizume, Y., Oda, T., 2006. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351, 602-611.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
3
-
-
0035377241
-
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7
-
Ardley, H.C., Tan, N.G., Rose, S.A., Markham, A.F., Robinson, P.A., 2001. Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7. J. Biol. Chem. 276, 19640-19647.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19640-19647
-
-
Ardley, H.C.1
Tan, N.G.2
Rose, S.A.3
Markham, A.F.4
Robinson, P.A.5
-
4
-
-
17144426507
-
Human, Drosophila, and C. elegans TDP43: Nucleic acid binding properties and splicing regulatory function
-
Ayala, Y.M., Pantano, S., D'Ambrogio, A., Buratti, E., Brindisi, A., Marchetti, C., Romano, M., Baralle, F.E., 2005. Human, Drosophila, and C. elegans TDP43: nucleic acid binding properties and splicing regulatory function. J. Mol. Biol. 348, 575-588.
-
(2005)
J. Mol. Biol.
, vol.348
, pp. 575-588
-
-
Ayala, Y.M.1
Pantano, S.2
D'Ambrogio, A.3
Buratti, E.4
Brindisi, A.5
Marchetti, C.6
Romano, M.7
Baralle, F.E.8
-
5
-
-
0033607801
-
Degradation of alpha-synuclein by proteasome
-
Bennett, M.C., Bishop, J.F., Leng, Y., Chock, P.B., Chase, T.N., Mouradian, M.M., 1999. Degradation of alpha-synuclein by proteasome. J. Biol. Chem. 274, 33855-33858.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33855-33858
-
-
Bennett, M.C.1
Bishop, J.F.2
Leng, Y.3
Chock, P.B.4
Chase, T.N.5
Mouradian, M.M.6
-
6
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti, E., Brindisi, A., Giombi, M., Tisminetzky, S., Ayala, Y.M., Baralle, F.E., 2005. TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J. Biol. Chem. 280, 37572-37584.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
7
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti, E., Baralle, F.E., 2008. Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front. Biosci. 13, 867-878.
-
(2008)
Front. Biosci.
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
8
-
-
68749107083
-
Parkin promotes intracellular Abeta1-42 clearance
-
Burns, M.P., Zhang, L., Rebeck, G.W., Querfurth, H.W., Moussa, C.E., 2009. Parkin promotes intracellular Abeta1-42 clearance. Hum. Mol. Genet. 18, 3206-3216.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3206-3216
-
-
Burns, M.P.1
Zhang, L.2
Rebeck, G.W.3
Querfurth, H.W.4
Moussa, C.E.5
-
9
-
-
70350454798
-
Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability
-
Caccamo, A., Majumder, S., Deng, J.J., Bai, Y., Thornton, F.B., Oddo, S., 2009. Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability. J. Biol. Chem. 284, 27416-27424.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27416-27424
-
-
Caccamo, A.1
Majumder, S.2
Deng, J.J.3
Bai, Y.4
Thornton, F.B.5
Oddo, S.6
-
10
-
-
78149318021
-
Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Abeta oligomers accumulation
-
Caccamo, A., Magri, A., Oddo, S., 2010. Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Abeta oligomers accumulation. Mol. Neurodegener. 5, 51.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 51
-
-
Caccamo, A.1
Magri, A.2
Oddo, S.3
-
11
-
-
0030769092
-
Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
Cook, D.G., Forman, M.S., Sung, J.C., Leight, S., Kolson, D.L., Iwatsubo, T., Lee, V.M., Doms, R.W., 1997. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat. Med. 3, 1021-1023.
-
(1997)
Nat. Med.
, vol.3
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
Lee, V.M.7
Doms, R.W.8
-
12
-
-
34247625005
-
Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43
-
DOI 10.1007/s00401-006-0189-y
-
Davidson, Y., Kelley, T., Mackenzie, I.R., Pickering-Brown, S., Du Plessis, D., Neary, D., Snowden, J.S., Mann, D.M., 2007. Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43. Acta Neuropathol. 113, 521-533. (Pubitemid 46672598)
-
(2007)
Acta Neuropathologica
, vol.113
, Issue.5
, pp. 521-533
-
-
Davidson, Y.1
Kelley, T.2
Mackenzie, I.R.A.3
Pickering-Brown, S.4
Du, P.D.5
Neary, D.6
Snowden, J.S.7
Mann, D.M.A.8
-
13
-
-
33744781515
-
Frontotemporal dementia: Clinicopathological correlations
-
Forman, M.S., Farmer, J., Johnson, J.K., Clark, C.M., Arnold, S.E., Coslett, H.B., Chatterjee, A., Hurtig, H.I., Karlawish, J.H., Rosen, H.J., Van Deerlin, V., Lee, V.M., Miller, B.L., Trojanowski, J.Q., Grossman, M., 2006. Frontotemporal dementia: clinicopathological correlations. Ann. Neurol. 59, 952-962.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 952-962
-
-
Forman, M.S.1
Farmer, J.2
Johnson, J.K.3
Clark, C.M.4
Arnold, S.E.5
Coslett, H.B.6
Chatterjee, A.7
Hurtig, H.I.8
Karlawish, J.H.9
Rosen, H.J.10
Van Deerlin, V.11
Lee, V.M.12
Miller, B.L.13
Trojanowski, J.Q.14
Grossman, M.15
-
14
-
-
36949036676
-
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
-
DOI 10.1007/s00401-007-0257-y
-
Geser, F., Winton, M.J., Kwong, L.K., Xu, Y., Xie, S.X., Igaz, L.M., Garruto, R.M., Perl, D.P., Galasko, D., Lee, V.M., Trojanowski, J.Q., 2008. Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. Acta Neuropathol. 115, 133-145. (Pubitemid 350238671)
-
(2008)
Acta Neuropathologica
, vol.115
, Issue.1
, pp. 133-145
-
-
Geser, F.1
Winton, M.J.2
Kwong, L.K.3
Xu, Y.4
Xie, S.X.5
Igaz, L.M.6
Garruto, R.M.7
Perl, D.P.8
Galasko, D.9
Lee, V.M.-Y.10
Trojanowski, J.Q.11
-
15
-
-
41949119043
-
TDP-43 A315T mutation in familial motor neuron disease
-
Gitcho, M.A., Baloh, R.H., Chakraverty, S., Mayo, K., Norton, J.B., Levitch, D., Hatanpaa, K.J., White III, C.L., Bigio, E.H., Caselli, R., Baker, M., Al-Lozi, M.T., Morris, J.C., Pestronk, A., Rademakers, R., Goate, A.M., Cairns, N.J., 2008. TDP-43 A315T mutation in familial motor neuron disease. Ann. Neurol. 63, 535-538.
-
(2008)
Ann. Neurol.
, vol.63
, pp. 535-538
-
-
Gitcho, M.A.1
Baloh, R.H.2
Chakraverty, S.3
Mayo, K.4
Norton, J.B.5
Levitch, D.6
Hatanpaa, K.J.7
White III, C.L.8
Bigio, E.H.9
Caselli, R.10
Baker, M.11
Al-Lozi, M.T.12
Morris, J.C.13
Pestronk, A.14
Rademakers, R.15
Goate, A.M.16
Cairns, N.J.17
-
16
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras, G.K., Tsai, J., Naslund, J., Vincent, B., Edgar, M., Checler, F., Greenfield, J.P., Haroutunian, V., Buxbaum, J.D., Xu, H., Greengard, P., Relkin, N.R., 2000. Intraneuronal Abeta42 accumulation in human brain. Am. J. Pathol. 156, 15-20.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
Greengard, P.11
Relkin, N.R.12
-
17
-
-
0033582159
-
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides
-
Greenfield, J.P., Tsai, J., Gouras, G.K., Hai, B., Thinakaran, G., Checler, F., Sisodia, S.S., Greengard, P., Xu, H., 1999. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proc. Natl Acad. Sci. USA 96, 742-747.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 742-747
-
-
Greenfield, J.P.1
Tsai, J.2
Gouras, G.K.3
Hai, B.4
Thinakaran, G.5
Checler, F.6
Sisodia, S.S.7
Greengard, P.8
Xu, H.9
-
18
-
-
33751250197
-
Genetics of familial and sporadic amyotrophic lateral sclerosis
-
Gros-Louis, F., Gaspar, C., Rouleau, G.A., 2006. Genetics of familial and sporadic amyotrophic lateral sclerosis. Biochim. Biophys. Acta 1762, 956-972.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 956-972
-
-
Gros-Louis, F.1
Gaspar, C.2
Rouleau, G.A.3
-
19
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass, C., Schlossmacher, M.G., Hung, A.Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B.L., Lieberburg, I., Koo, E.H., Schenk, D., Teplow, D.B., et al., 1992. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359, 322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
-
20
-
-
0029097783
-
Distribution of tangles and threads in the cerebral cortex in progressive supranuclear palsy
-
Hanihara, T., Amano, N., Takahashi, T., Nagatomo, H., Yagashita, S., 1995. Distribution of tangles and threads in the cerebral cortex in progressive supranuclear palsy. Neuropathol. Appl. Neurobiol. 21, 319-326.
-
(1995)
Neuropathol. Appl. Neurobiol.
, vol.21
, pp. 319-326
-
-
Hanihara, T.1
Amano, N.2
Takahashi, T.3
Nagatomo, H.4
Yagashita, S.5
-
21
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy, J., Selkoe, D.J., 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
22
-
-
34249709931
-
TDP-43 is deposited in the Guam parkinsonism-dementia complex brains
-
DOI 10.1093/brain/awm065
-
Hasegawa, M., Arai, T., Akiyama, H., Nonaka, T., Mori, H., Hashimoto, T., Yamazaki, M., Oyanagi, K., 2007. TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain 130, 1386-1394. (Pubitemid 47355958)
-
(2007)
Brain
, vol.130
, Issue.5
, pp. 1386-1394
-
-
Hasegawa, M.1
Arai, T.2
Akiyama, H.3
Nonaka, T.4
Mori, H.5
Hashimoto, T.6
Yamazaki, M.7
Oyanagi, K.8
-
23
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa, M., Arai, T., Nonaka, T., Kametani, F., Yoshida, M., Hashizume, Y., Beach, T.G., Buratti, E., Baralle, F., Morita, M., Nakano, I., Oda, T., Tsuchiya, K., Akiyama, H., 2008. Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann. Neurol. 64, 60-70.
-
(2008)
Ann. Neurol.
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
Beach, T.G.7
Buratti, E.8
Baralle, F.9
Morita, M.10
Nakano, I.11
Oda, T.12
Tsuchiya, K.13
Akiyama, H.14
-
24
-
-
0026721235
-
Distribution of cortical neurofibrillary tangles in progressive supranuclear palsy: A quantitative analysis of six cases
-
Hof, P.R., Delacourte, A., Bouras, C., 1992. Distribution of cortical neurofibrillary tangles in progressive supranuclear palsy: a quantitative analysis of six cases. Acta Neuropathol. 84, 45-51.
-
(1992)
Acta Neuropathol.
, vol.84
, pp. 45-51
-
-
Hof, P.R.1
Delacourte, A.2
Bouras, C.3
-
25
-
-
0037047311
-
Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome
-
Hyun, D.H., Lee, M., Hattori, N., Kubo, S., Mizuno, Y., Halliwell, B., Jenner, P., 2002. Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome. J. Biol. Chem. 277, 28572-28577.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28572-28577
-
-
Hyun, D.H.1
Lee, M.2
Hattori, N.3
Kubo, S.4
Mizuno, Y.5
Halliwell, B.6
Jenner, P.7
-
26
-
-
43649103517
-
Astrocytic tau pathology positively correlates with neurofibrillary tangle density in progressive supranuclear palsy
-
Ito, K., Arai, K., Yoshiyama, Y., Kashiwado, K., Sakakibara, Y., Hattori, T., 2008. Astrocytic tau pathology positively correlates with neurofibrillary tangle density in progressive supranuclear palsy. Acta Neuropathol. 115, 623-628.
-
(2008)
Acta Neuropathol.
, vol.115
, pp. 623-628
-
-
Ito, K.1
Arai, K.2
Yoshiyama, Y.3
Kashiwado, K.4
Sakakibara, Y.5
Hattori, T.6
-
27
-
-
78049368074
-
Parkinson-related parkin reduces alpha-Synuclein phosphorylation in a gene transfer model
-
Khandelwal, P.J., Dumanis, S.B., Feng, L.R., Maguire-Zeiss, K., Rebeck, G., Lashuel, H.A., Moussa, C.E., 2010. Parkinson-related parkin reduces alpha-Synuclein phosphorylation in a gene transfer model. Mol. Neurodegener. 5, 47.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 47
-
-
Khandelwal, P.J.1
Dumanis, S.B.2
Feng, L.R.3
Maguire-Zeiss, K.4
Rebeck, G.5
Lashuel, H.A.6
Moussa, C.E.7
-
28
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo, E.H., Squazzo, S.L., 1994. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 269, 17386-17389.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
29
-
-
0031746979
-
A detergent-insoluble membrane compartment contains A beta in vivo
-
Lee, S.J., Liyanage, U., Bickel, P.E., Xia, W., Lansbury Jr., P.T., Kosik, K.S., 1998. A detergent-insoluble membrane compartment contains A beta in vivo. Nat. Med. 4, 730-734.
-
(1998)
Nat. Med.
, vol.4
, pp. 730-734
-
-
Lee, S.J.1
Liyanage, U.2
Bickel, P.E.3
Xia, W.4
Lansbury Jr., P.T.5
Kosik, K.S.6
-
30
-
-
0034940160
-
Neurodegenerative tauopathies
-
Lee, V.M., Goedert, M., Trojanowski, J.Q., 2001. Neurodegenerative tauopathies. Annu. Rev. Neurosci. 24, 1121-1159.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1121-1159
-
-
Lee, V.M.1
Goedert, M.2
Trojanowski, J.Q.3
-
31
-
-
0037044240
-
The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
-
Lomen-Hoerth, C., Anderson, T., Miller, B., 2002. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. Neurology 59, 1077-1079.
-
(2002)
Neurology
, vol.59
, pp. 1077-1079
-
-
Lomen-Hoerth, C.1
Anderson, T.2
Miller, B.3
-
32
-
-
0037426388
-
Are amyotrophic lateral sclerosis patients cognitively normal?
-
Lomen-Hoerth, C., Murphy, J., Langmore, S., Kramer, J.H., Olney, R.K., Miller, B., 2003. Are amyotrophic lateral sclerosis patients cognitively normal? Neurology 60, 1094-1097.
-
(2003)
Neurology
, vol.60
, pp. 1094-1097
-
-
Lomen-Hoerth, C.1
Murphy, J.2
Langmore, S.3
Kramer, J.H.4
Olney, R.K.5
Miller, B.6
-
33
-
-
34249946466
-
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
-
Mackenzie, I.R., Bigio, E.H., Ince, P.G., Geser, F., Neumann, M., Cairns, N.J., Kwong, L.K., Forman, M.S., Ravits, J., Stewart, H., Eisen, A., McClusky, L., Kretzschmar, H.A., Monoranu, C.M., Highley, J.R., Kirby, J., Siddique, T., Shaw, P.J., Lee, V.M., Trojanowski, J.Q., 2007. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann. Neurol. 61, 427-434.
-
(2007)
Ann. Neurol.
, vol.61
, pp. 427-434
-
-
Mackenzie, I.R.1
Bigio, E.H.2
Ince, P.G.3
Geser, F.4
Neumann, M.5
Cairns, N.J.6
Kwong, L.K.7
Forman, M.S.8
Ravits, J.9
Stewart, H.10
Eisen, A.11
McClusky, L.12
Kretzschmar, H.A.13
Monoranu, C.M.14
Highley, J.R.15
Kirby, J.16
Siddique, T.17
Shaw, P.J.18
Lee, V.M.19
Trojanowski, J.Q.20
more..
-
34
-
-
0036868476
-
Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein
-
Morales, B., Martinez, A., Gonzalo, I., Vidal, L., Ros, R., Gomez-Tortosa, E., Rabano, A., Ampuero, I., Sanchez, M., Hoenicka, J., Garcia De Yebenes, J., 2002. Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein. Mov. Disord. 17, 1374-1380.
-
(2002)
Mov. Disord.
, vol.17
, pp. 1374-1380
-
-
Morales, B.1
Martinez, A.2
Gonzalo, I.3
Vidal, L.4
Ros, R.5
Gomez-Tortosa, E.6
Rabano, A.7
Ampuero, I.8
Sanchez, M.9
Hoenicka, J.10
Garcia De Yebenes, J.11
-
35
-
-
0033151716
-
A novel transactivation domain in parkin
-
Morett, E., Bork, P., 1999. A novel transactivation domain in parkin. Trends Biochem. Sci. 24, 229-231.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 229-231
-
-
Morett, E.1
Bork, P.2
-
36
-
-
33645062075
-
A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia
-
Morita, M., Al-Chalabi, A., Andersen, P.M., Hosler, B., Sapp, P., Englund, E., Mitchell, J.E., Habgood, J.J., de Belleroche, J., Xi, J., Jongjaroenprasert, W., Horvitz, H.R., Gunnarsson, L.G., Brown Jr., R.H., 2006. A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology 66, 839-844.
-
(2006)
Neurology
, vol.66
, pp. 839-844
-
-
Morita, M.1
Al-Chalabi, A.2
Andersen, P.M.3
Hosler, B.4
Sapp, P.5
Englund, E.6
Mitchell, J.E.7
Habgood, J.J.8
De Belleroche, J.9
Xi, J.10
Jongjaroenprasert, W.11
Horvitz, H.R.12
Gunnarsson, L.G.13
Brown Jr., R.H.14
-
37
-
-
23844445158
-
Clinicopathological features of the tauopathies
-
Murray, B., Lynch, T., Farrell, M., 2005. Clinicopathological features of the tauopathies. Biochem. Soc. Trans. 33, 595-599.
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 595-599
-
-
Murray, B.1
Lynch, T.2
Farrell, M.3
-
38
-
-
34547733547
-
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases
-
DOI 10.1007/s00401-007-0261-2
-
Nakashima-Yasuda, H., Uryu, K., Robinson, J., Xie, S.X., Hurtig, H., Duda, J.E., Arnold, S.E., Siderowf, A., Grossman, M., Leverenz, J.B., Woltjer, R., Lopez, O.L., Hamilton, R., Tsuang, D.W., Galasko, D., Masliah, E., Kaye, J., Clark, C.M., Montine, T.J., Lee, V.M., Trojanowski, J.Q., 2007. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathol. 114, 221-229. (Pubitemid 47226148)
-
(2007)
Acta Neuropathologica
, vol.114
, Issue.3
, pp. 221-229
-
-
Nakashima-Yasuda, H.1
Uryu, K.2
Robinson, J.3
Xie, S.X.4
Hurtig, H.5
Duda, J.E.6
Arnold, S.E.7
Siderowf, A.8
Grossman, M.9
Leverenz, J.B.10
Woltjer, R.11
Lopez, O.L.12
Hamilton, R.13
Tsuang, D.W.14
Galasko, D.15
Masliah, E.16
Kaye, J.17
Clark, C.M.18
Montine, T.J.19
Lee, V.M.-Y.20
Trojanowski, J.Q.21
more..
-
39
-
-
0025014964
-
Frontal lobe dementia and motor neuron disease
-
Neary, D., Snowden, J.S., Mann, D.M., Northen, B., Goulding, P.J., Macdermott, N., 1990. Frontal lobe dementia and motor neuron disease. J. Neurol. Neurosurg. Psychiatry 53, 23-32.
-
(1990)
J. Neurol. Neurosurg. Psychiatry
, vol.53
, pp. 23-32
-
-
Neary, D.1
Snowden, J.S.2
Mann, D.M.3
Northen, B.4
Goulding, P.J.5
Macdermott, N.6
-
40
-
-
0034528007
-
Classification and description of frontotemporal dementias
-
Neary, D., Snowden, J.S., Mann, D.M., 2000. Classification and description of frontotemporal dementias. Ann. NY Acad. Sci. 920, 46-51.
-
(2000)
Ann. NY Acad. Sci.
, vol.920
, pp. 46-51
-
-
Neary, D.1
Snowden, J.S.2
Mann, D.M.3
-
41
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1126/science.1134108
-
Neumann, M., Sampathu, D.M., Kwong, L.K., Truax, A.C., Micsenyi, M.C., Chou, T.T., Bruce, J., Schuck, T., Grossman, M., Clark, C.M., McCluskey, L.F., Miller, B.L., Masliah, E., Mackenzie, I.R., Feldman, H., Feiden, W., Kretzschmar, H.A., Trojanowski, J.Q., Lee, V.M., 2006. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133. (Pubitemid 44547757)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.-Y.19
-
42
-
-
35348853257
-
TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: Protein misfolding diseases without amyloidosis
-
Neumann, M., Kwong, L.K., Sampathu, D.M., Trojanowski, J.Q., Lee, V.M., 2007a. TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: protein misfolding diseases without amyloidosis. Arch. Neurol. 64, 1388-1394.
-
(2007)
Arch. Neurol.
, vol.64
, pp. 1388-1394
-
-
Neumann, M.1
Kwong, L.K.2
Sampathu, D.M.3
Trojanowski, J.Q.4
Lee, V.M.5
-
43
-
-
33846815066
-
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations
-
Neumann, M., Mackenzie, I.R., Cairns, N.J., Boyer, P.J., Markesbery, W.R., Smith, C.D., Taylor, J.P., Kretzschmar, H.A., Kimonis, V.E., Forman, M.S., 2007b. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. J. Neuropathol. Exp. Neurol. 66, 152-157.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 152-157
-
-
Neumann, M.1
Mackenzie, I.R.2
Cairns, N.J.3
Boyer, P.J.4
Markesbery, W.R.5
Smith, C.D.6
Taylor, J.P.7
Kretzschmar, H.A.8
Kimonis, V.E.9
Forman, M.S.10
-
44
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
-
Pasinelli, P., Brown, R.H., 2006. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7, 710-723.
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
45
-
-
0037062609
-
The prevalence of frontotemporal dementia
-
Ratnavalli, E., Brayne, C., Dawson, K., Hodges, J.R., 2002. The prevalence of frontotemporal dementia. Neurology 58, 1615-1621. (Pubitemid 34602891)
-
(2002)
Neurology
, vol.58
, Issue.11
, pp. 1615-1621
-
-
Ratnavalli, E.1
Brayne, C.2
Dawson, K.3
Hodges, J.R.4
-
46
-
-
77951226607
-
Beta-Amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss
-
Rebeck, G.W., Hoe, H.S., Moussa, C.E., 2010. beta]-Amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss. J. Biol. Chem.
-
(2010)
J. Biol. Chem.
-
-
Rebeck, G.W.1
Hoe, H.S.2
Moussa, C.E.3
-
47
-
-
40749134969
-
Parkin polymorphisms in progressive supranuclear palsy
-
Ros, R., Ampuero, I., Garcia de Yebenes, J., 2008. Parkin polymorphisms in progressive supranuclear palsy. J. Neurol. Sci. 268, 176-178.
-
(2008)
J. Neurol. Sci.
, vol.268
, pp. 176-178
-
-
Ros, R.1
Ampuero, I.2
Garcia De Yebenes, J.3
-
48
-
-
0027164824
-
Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis (Nature (1993) 362 (59-62))
-
Rosen, D.R., 1993. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 364, 362. (Pubitemid 23265284)
-
(1993)
Nature
, vol.364
, Issue.6435
, pp. 362
-
-
Rosen, D.R.1
-
49
-
-
0036812559
-
Progressive supranuclear palsy and tau hyperphosphorylation in a patient with a C212Y parkin mutation
-
Sanchez, M.P., Gonzalo, I., Avila, J., De Yebenes, J.G., 2002. Progressive supranuclear palsy and tau hyperphosphorylation in a patient with a C212Y parkin mutation. J. Alzheimers Dis. 4, 399-404. (Pubitemid 35397805)
-
(2002)
Journal of Alzheimer's Disease
, vol.4
, Issue.5
, pp. 399-404
-
-
Sanchez, M.P.1
Gonzalo, I.2
Avila, J.3
De Yebenes, J.G.4
-
50
-
-
0031781642
-
Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture
-
DOI 10.1083/jcb.141.4.1031
-
Skovronsky, D.M., Doms, R.W., Lee, V.M., 1998. Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture. J. Cell Biol. 141, 1031-1039. (Pubitemid 28243969)
-
(1998)
Journal of Cell Biology
, vol.141
, Issue.4
, pp. 1031-1039
-
-
Skovronsky, D.M.1
Doms, R.W.2
Lee, V.M.-Y.3
-
51
-
-
0036160338
-
Frontotemporal dementia
-
DOI 10.1192/bjp.180.2.140
-
Snowden, J.S., Neary, D., Mann, D.M., 2002. Frontotemporal dementia. Br. J. Psychiatry 180, 140-143. (Pubitemid 34142785)
-
(2002)
British Journal of Psychiatry
, vol.180
, Issue.FEB.
, pp. 140-143
-
-
Snowden, J.S.1
Neary, D.2
Mann, D.M.A.3
-
52
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
DOI 10.1126/science.1154584
-
Sreedharan, J., Blair, I.P., Tripathi, V.B., Hu, X., Vance, C., Rogelj, B., Ackerley, S., Durnall, J.C., Williams, K.L., Buratti, E., Baralle, F., de Belleroche, J., Mitchell, J.D., Leigh, P.N., Al-Chalabi, A., Miller, C.C., Nicholson, G., Shaw, C.E., 2008. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 319, 1668-1672. (Pubitemid 351432505)
-
(2008)
Science
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
De Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
53
-
-
33749002522
-
Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: Common pathways in neurodegenerative disease
-
Talbot, K., Ansorge, O., 2006. Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease. Hum. Mol. Genet. 15 Spec No 2, R182-R187.
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.SPEC NO 2
-
-
Talbot, K.1
Ansorge, O.2
-
54
-
-
34247606414
-
TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation
-
DOI 10.1007/s00401-007-0206-9
-
Tan, C.F., Eguchi, H., Tagawa, A., Onodera, O., Iwasaki, T., Tsujino, A., Nishizawa, M., Kakita, A., Takahashi, H., 2007. TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol. 113, 535-542. (Pubitemid 46672599)
-
(2007)
Acta Neuropathologica
, vol.113
, Issue.5
, pp. 535-542
-
-
Tan, C.-F.1
Eguchi, H.2
Tagawa, A.3
Onodera, O.4
Iwasaki, T.5
Tsujino, A.6
Nishizawa, M.7
Kakita, A.8
Takahashi, H.9
-
55
-
-
0035976835
-
alpha-Synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome
-
DOI 10.1016/S0014-5793(01)03115-5, PII S0014579301031155
-
Tofaris, G.K., Layfield, R., Spillantini, M.G., 2001. alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome. FEBS Lett. 509, 22-26. (Pubitemid 33153074)
-
(2001)
FEBS Letters
, vol.509
, Issue.1
, pp. 22-26
-
-
Tofaris, G.K.1
Layfield, R.2
Spillantini, M.G.3
-
56
-
-
0035957112
-
Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations
-
van de Warrenburg, B.P., Lammens, M., Lucking, C.B., Denefle, P., Wesseling, P., Booij, J., Praamstra, P., Quinn, N., Brice, A., Horstink, M.W., 2001. Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations. Neurology 56, 555-557. (Pubitemid 32172889)
-
(2001)
Neurology
, vol.56
, Issue.4
, pp. 555-557
-
-
Van De, W.B.P.C.1
Lammens, M.2
Lucking, C.B.3
Denefle, P.4
Wesseling, P.5
Booij, J.6
Praamstra, P.7
Quinn, N.8
Brice, A.9
Horstink, M.W.I.M.10
-
57
-
-
0344256486
-
Structural diversity and functional implications of the eukaryotic TDP gene family
-
DOI 10.1016/S0888-7543(03)00214-3
-
Wang, H.Y., Wang, I.F., Bose, J., Shen, C.K., 2004. Structural diversity and functional implications of the eukaryotic TDP gene family. Genomics 83, 130-139. (Pubitemid 37518267)
-
(2004)
Genomics
, vol.83
, Issue.1
, pp. 130-139
-
-
Wang, H.-Y.1
Wang, I.-F.2
Bose, J.3
Shen, C.-K.J.4
-
58
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska, I., Bell, S., Cairns, N.J., Miller, T.M., Baloh, R.H., 2009. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl Acad. Sci. USA 106, 18809-18814.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
59
-
-
0032800818
-
Intracellular APP processing and A beta production in Alzheimer disease
-
Wilson, C.A., Doms, R.W., Lee, V.M., 1999. Intracellular APP processing and A beta production in Alzheimer disease. J. Neuropathol. Exp. Neurol. 58, 787-794.
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 787-794
-
-
Wilson, C.A.1
Doms, R.W.2
Lee, V.M.3
-
60
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton, M.J., Igaz, L.M., Wong, M.M., Kwong, L.K., Trojanowski, J.Q., Lee, V.M., 2008. Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem. 283, 13302-13309.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
61
-
-
0030963605
-
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
-
Xu, H., Sweeney, D., Wang, R., Thinakaran, G., Lo, A.C., Sisodia, S.S., Greengard, P., Gandy, S., 1997. Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation. Proc. Natl Acad. Sci. USA 94, 3748-3752.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3748-3752
-
-
Xu, H.1
Sweeney, D.2
Wang, R.3
Thinakaran, G.4
Lo, A.C.5
Sisodia, S.S.6
Greengard, P.7
Gandy, S.8
-
62
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
DOI 10.1523/JNEUROSCI.3421-07.2007
-
Zhang, Y.J., Xu, Y.F., Dickey, C.A., Buratti, E., Baralle, F., Bailey, R., Pickering-Brown, S., Dickson, D., Petrucelli, L., 2007. Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 27, 10530-10534. (Pubitemid 47501990)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.39
, pp. 10530-10534
-
-
Zhang, Y.-J.1
Xu, Y.-F.2
Dickey, C.A.3
Buratti, E.4
Baralle, F.5
Bailey, R.6
Pickering-Brown, S.7
Dickson, D.8
Petrucelli, L.9
-
63
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang, Y.J., Xu, Y.F., Cook, C., Gendron, T.F., Roettges, P., Link, C.D., Lin, W.L., Tong, J., Castanedes-Casey, M., Ash, P., Gass, J., Rangachari, V., Buratti, E., Baralle, F., Golde, T.E., Dickson, D.W., Petrucelli, L., 2009. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc. Natl Acad. Sci. USA 106, 7607-7612.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
Link, C.D.6
Lin, W.L.7
Tong, J.8
Castanedes-Casey, M.9
Ash, P.10
Gass, J.11
Rangachari, V.12
Buratti, E.13
Baralle, F.14
Golde, T.E.15
Dickson, D.W.16
Petrucelli, L.17
|