Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models

Experimental Neurology

Volumn 235, Issue 1, 2012, Pages 297-305

  Herman, Alexander M ^a   Khandelwal, Preeti J ^a   Rebeck, G William ^a   Moussa, Charbel E H ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

secretase; Alzheimer's disease; Amyloid precursor protein; Fronto temporal lobar dementia; Neurodegeneration; Transactivation DNA binding protein 43

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CALCIUM BINDING PROTEIN; DNA BINDING PROTEIN; INTERLEUKIN 6; TRANSACTIVATION DNA BINDING PROTEIN 43; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION; GENE TRANSFER; IMMUNOHISTOLOGY; LENTIVIRINAE; MALE; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RAT; TRANSACTIVATION; UBIQUITINATION; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; DNA-BINDING PROTEINS; ENCEPHALITIS; GENE TRANSFER TECHNIQUES; INTERLEUKIN-6; LENTIVIRUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859913759     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.02.011     Document Type: Article

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