Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

Nature Neuroscience

Volumn 15, Issue 11, 2012, Pages 1488-1497

  Lagier Tourenne, Clotilde ^a   Polymenidou, Magdalini ^a   Hutt, Kasey R ^a   Vu, Anthony Q ^a   Baughn, Michael ^b   Huelga, Stephanie C ^a   Clutario, Kevin M ^a   Ling, Shuo Chien ^a   Liang, Tiffany Y ^a   Mazur, Curt ^c   Wancewicz, Edward ^c   Kim, Aneeza S ^c   Watt, Andy ^c   Freier, Sue ^c   Hicks, Geoffrey G ^d   Donohue, John Paul ^e   Shiue, Lily ^e   Bennett, C Frank ^c   Ravits, John ^b   Cleveland, Don W ^a   Yeo, Gene W ^a,f   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ISIS PHARMACEUTICALS   (United States)

^d UNIVERSITY OF MANITOBA   (Canada)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

FUSED IN SARCOMA PROTEIN; MESSENGER RNA; MESSENGER RNA PRECURSOR; TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; MOTONEURON; MOUSE; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN RNA BINDING; RNA PROCESSING; RNA SPLICING; RNA TRANSCRIPTION; STEM CELL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; DNA-BINDING PROTEINS; EXCITATORY AMINO ACID TRANSPORTER 2; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; IMMUNOPRECIPITATION; KV CHANNEL-INTERACTING PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR NEURONS; NERVE TISSUE PROTEINS; NEURAL CELL ADHESION MOLECULES; NEURAL STEM CELLS; NEUROFILAMENT PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA PRECURSORS; RNA SPLICING; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-BINDING PROTEIN FUS; SHAL POTASSIUM CHANNELS; SPINAL CORD; TAU PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 84868152371     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3230     Document Type: Article

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